WO2009102191A1 - Health supplement composition of sea cucumber - Google Patents

Health supplement composition of sea cucumber Download PDF

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Publication number
WO2009102191A1
WO2009102191A1 PCT/MY2009/000030 MY2009000030W WO2009102191A1 WO 2009102191 A1 WO2009102191 A1 WO 2009102191A1 MY 2009000030 W MY2009000030 W MY 2009000030W WO 2009102191 A1 WO2009102191 A1 WO 2009102191A1
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WIPO (PCT)
Prior art keywords
sea cucumber
extract
composition
present
composition according
Prior art date
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PCT/MY2009/000030
Other languages
French (fr)
Inventor
Mohd Effendy Abd Wahid
Peng Kin Tan
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Universiti Malaysia Terengganu
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Publication of WO2009102191A1 publication Critical patent/WO2009102191A1/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/616—Echinodermata, e.g. starfish, sea cucumbers or sea urchins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L17/00—Food-from-the-sea products; Fish products; Fish meal; Fish-egg substitutes; Preparation or treatment thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/42—Cucurbitaceae (Cucumber family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Definitions

  • the present invention relates to a health supplement composition.
  • the present invention relates to a medicinal composition comprising sea cucumber (gamat) and chicory, to be taken orally as general health supplement.
  • the sea cucumber is an echinoderm of the class Holothuroidea, which is always found on the sea floor. It possesses an elongated body with leathery skin. Generally, 90% of the sea cucumber's tissues including the body walls, muscles, gonads and intestine are edible.
  • sea cucumber The increase of the market demand for sea cucumber relates directly to the progression of pharmaceutical industries. Its high contents of polysaccharide sulphate, glycoprotein, fucans and lectins are suitable for the development of therapeutic drugs for arthritis, cancer or HIV treatments.
  • the chemical contents in sea cucumber are capable of enhancing blood circulation, reducing high blood pressure, soothing joint inflammation, reducing weariness and others.
  • This composition can be a product of external preparation or a food and beverage which is capable of exhibiting high beautiful skin effect and preventing aging symptoms such as wrinkles, flabbiness or chapped skin.
  • compositions containing sea cucumber for treating bone and joint inflammation disclosed in PCT publication No. WO9852583.
  • the composition also possesses one or any combination of a mucopolysaccharide, proteolytic enzymes, herbs of the genus Withenia, genus Panax and genus Salix, chondroitin, black currant oil and others.
  • the external preparations or edible products made from sea cucumber are increasingly gaining its popularity over the world year after year.
  • sea cucumber contains a lot of active compounds responsible for its therapeutic properties, especially its wound-healing effect
  • an innovative formulation of the products made of sea cucumber is thus desirable. This can be achieved by adding other herbs into its formulation to enhance its effectiveness as well as its taste so that the products can benefit more consumers.
  • An innovative preparation method is also needed so as to conserve the active compounds in the sea cucumber.
  • the primary object of the present invention is to develop a medicinal composition comprising sea cucumber (gamat) and chicory as a general health supplement.
  • Another object of the present invention is to improve the nutritional or medicinal values as well as enhancing the taste of the sea cucumber health supplement by the addition of an extract of chicory into the composition.
  • Yet another object of the present invention is to develop a preparation method for sea cucumber products which is capable of conserving active compounds in the sea cucumbers.
  • At least one of the preceding objects is met, in whole or in part, by the present invention, in which one of the embodiments of the present invention describes a health supplement composition comprising an extract of sea cucumber and an extract of a herb of the genus Cichorium.
  • Another embodiment of the present invention is a health supplement composition further comprising a sweetener and a preservative.
  • FIG. 1 is a schematic diagram of a health supplement composition
  • FIG. 1 is a schematic diagram of a health supplement composition
  • FIG. 1 is a schematic diagram of a health supplement composition
  • FIG. 1 is a schematic diagram of a health supplement composition
  • the present invention relates to a health supplement composition.
  • the present invention relates to a nutritious composition comprising sea cucumber and chicory, to be taken orally as general health supplement.
  • the present invention discloses a health supplement composition
  • a health supplement composition comprising an extract of sea cucumber and an extract of a herb of the genus Cichorium.
  • the sea cucumber used is selected from the species of Stichopus horrens, Stichopus variegatus,
  • the sea cucumber used in this health supplement composition is Stichopus variegatus. It is one of the several species of golden sea cucumber which is also known as gamat emas.
  • the extract of the sea cucumber is commercially obtained.
  • the dried body parts of sea cucumber, including the body walls, muscles and others are employed to acquire the gamat extract.
  • the sea cucumber is present in an amount of 18% to 22% by weight of the composition. Most preferably, the percentage of sea cucumber in this composition is 20%. As described by the most preferred embodiment of the present invention, 3g of the extract of Stichopus variegatus is required to be dissolved in sterilized reverse osmosis water for acquiring a 15ml gamat solution.
  • the active compounds contained in Stichopus variegatus possesses a lot of medicinal and nutritional values.
  • the polysaccharide condroition sulphate is capable of reducing athritic pain.
  • its glycoprotein, fucans and lectins content are also useful for the development of therapeutic drugs for arthritis, cancer or HFV treatments.
  • the active compounds help enhancing blood circulation, reducing high blood pressure, soothing joint inflammation, reducing weariness and providing other therapeutic effects.
  • the Stichopus variegatus also possesses eicopentaenoic acid (EPA), Docosahexanoic acid (DHA) and vitamins which are crucial for wound healing and anti-aging. Since wound is a discruption of the anatomic structure that responsible for a particular function, treating wound is essential as it is the first root for bacteria and virus infection. A chronic disease condition such as diabetic case could create further complications to the would-healing process.
  • the composition of the present invention is capable of hasten the healing process as it also contains holothurin which helps to enhance the immunity of the body system. The collagen content in this composition also helps in rebuilding and increasing the elasticity of skin tissues.
  • the sea cucumber extract is anti-thrombotic and helps to reduce the risks of stroke by preventing the arteries from blood clots and blood fat. Besides, it also contains 18 types of amino acids, including asparagic, acid theorine, serine, glutamic acid, praline, phenylalanine, lysine, ammonia, histidine, arginine and others. Some essential minerals such as selenium, calcium and zinc also present in the extract.
  • an extract of a herb of the genus Cichorium is employed.
  • the herb used is Cichorium intybus.
  • It is a flowering plant generally known as chicory.
  • Chicory is capable of enhancing the growth of probiotics, such as Lactobacillus spp. which are beneficial to the human digestive system.
  • Chicory is also a remedy for dyspnea, loss of appetite, kidney and gall stone problems, intestinal worm and type II diabetes. Being an inulin producer, chicory is deemed as a dietary fibre suitable for the children.
  • chicory of the present invention also functions as a natural sweetener and glucose level balancer. With the addition of chicory, the health supplement product of the present invention can also helps in the elimination of intestine worm among the kids.
  • the extract of Cichorium intybus used is derived from its radix or root which is available in powder form.
  • the Cichorium intybus is present in an amount of 1.5% to 2.0% by weight of the composition.
  • the percentage of Cichorium extract in this composition is 1.8%.
  • 0.27g of the extract of Cichorium intybus is dissolved in sterilized reverse osmosis water when a 15ml gamat solution is prepared.
  • Another embodiment of the present invention is a health supplement composition which further comprises a sweetener and a preservative.
  • the sweetener is present in an amount of 0.5% to 1.0% by weight of the composition. Most preferably, the percentage of melon extract in this composition is 0.8%.
  • the preferred sweetener of this health supplement invented is melon extract.
  • the preservative used in the present invention can be sodium benzoate, potassium sorbate or the combination thereof.
  • the preservative used in the present invention is a combination of sodium benzoate and potassium sorbate.
  • Another embodiment of the present invention is a method for preparing a health supplement composition comprising dissolving an extract of sea cucumber and an extract of a herb of the genus Cichorium in sterilized reverse osmosis water.
  • the method for preparing the health supplement of the present invention is initiated by choosing the raw materials from proper channel.
  • a general quality control scheme is applied to the raw materials, including examination of their colour, pH and sterility.
  • the raw materials, extract of sea cucumber, extract of chicory, sweetener and preservatives are weighed respectively to obtain an appropriate quantity for a product of gamat.
  • the reverse osmosis water to be used in the present invention is undergone a double- sterilization process before it is used.
  • the reverse osmosis water is sterilized by ozone and then by ultraviolet to give a bacterial-free solvent for the preparation of the gamat solution. All raw materials are water-based and soluble in this sterilized reverse osmosis water. Finally, the dissolved sea cucumber extract and the additives are subjected to bottling, packaging and labeling.
  • the health supplement composition invented is in the form of solution which is golden yellow in colour.
  • the solution is preferably taken orally.
  • Experimental results of the product's effectiveness have shown that the extract of sea cucumber is capable of healing cut in a shorter period when the solution is taken orally than when it is applied on the surface of the cut.
  • the consumption of this health supplement will increase the elasticity of the skin tissue due to their collagen content but will not result in any toxicity in the liver nor kidney.
  • This product is suitable for the consumption of the post-operation patients, mothers after birth, elderlys, patients with menopause problems, premenstrual syndromes or sexual difficulties, type II diabetes, depression, or weariness.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Botany (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Pain & Pain Management (AREA)
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Abstract

A health supplement composition comprising an extract of sea cucumber and an extract of a herb of the genus Cichorium.

Description

HEALTH SUPPLEMENT COMPOSITION OF SEA CUCUMBER
FIELD OF INVENTION
The present invention relates to a health supplement composition. In more particular, the present invention relates to a medicinal composition comprising sea cucumber (gamat) and chicory, to be taken orally as general health supplement.
BACKGROUND OF THE INVENTION
The sea cucumber is an echinoderm of the class Holothuroidea, which is always found on the sea floor. It possesses an elongated body with leathery skin. Generally, 90% of the sea cucumber's tissues including the body walls, muscles, gonads and intestine are edible.
Several species of this animal are often used as the main ingredient in medicinal remedies, which is called gamat in Malay word. Gamat is highly demanded in Malaysia as well as other Asia regions due to the public's belief of its excellent therapeutic value. Gamat usually refers to the dried, powdered bodies of sea cucumbers made into various types of nutritious food or cosmetic products, such as supplement, tea, lotion, salve, facial mask and others. The main beneficial effect of sea cucumber is the property to heal cuts, skin eruptions and ulcers. Apart from their antibacterial and antifungal properties, sea cucumbers are also believed to be endowed with aphrodisiac powers.
The increase of the market demand for sea cucumber relates directly to the progression of pharmaceutical industries. Its high contents of polysaccharide sulphate, glycoprotein, fucans and lectins are suitable for the development of therapeutic drugs for arthritis, cancer or HIV treatments. The chemical contents in sea cucumber are capable of enhancing blood circulation, reducing high blood pressure, soothing joint inflammation, reducing weariness and others.
There are various types of health products made from sea cucumbers patented in the prior arts. These patented technologies include a wide variation in their formulations and product qualities.
Of interest in connection with a composition for beautiful skin comprising sea cucumber in combination with sea squirt is Japanese Patent No. JP2006089385. This composition can be a product of external preparation or a food and beverage which is capable of exhibiting high beautiful skin effect and preventing aging symptoms such as wrinkles, flabbiness or chapped skin.
There is another natural composition containing sea cucumber for treating bone and joint inflammation disclosed in PCT publication No. WO9852583. Besides sea cucumber, the composition also possesses one or any combination of a mucopolysaccharide, proteolytic enzymes, herbs of the genus Withenia, genus Panax and genus Salix, chondroitin, black currant oil and others.
In another PCT publication No. WO2007005349, an improved method for processing sea cucumber with a new composition produced are disclosed. This patent aims to provide a composition of matter produced from sea cucumber intestinal mass, and a method for producing same. The extract of sea cucumber produced can be used as raw material in the nutritious health sector to be further developed into other products.
The external preparations or edible products made from sea cucumber are increasingly gaining its popularity over the world year after year. As the sea cucumber contains a lot of active compounds responsible for its therapeutic properties, especially its wound-healing effect, an innovative formulation of the products made of sea cucumber is thus desirable. This can be achieved by adding other herbs into its formulation to enhance its effectiveness as well as its taste so that the products can benefit more consumers. An innovative preparation method is also needed so as to conserve the active compounds in the sea cucumber.
SUMMARY OF INVENTION
The primary object of the present invention is to develop a medicinal composition comprising sea cucumber (gamat) and chicory as a general health supplement.
Another object of the present invention is to improve the nutritional or medicinal values as well as enhancing the taste of the sea cucumber health supplement by the addition of an extract of chicory into the composition.
Yet another object of the present invention is to develop a preparation method for sea cucumber products which is capable of conserving active compounds in the sea cucumbers.
At least one of the preceding objects is met, in whole or in part, by the present invention, in which one of the embodiments of the present invention describes a health supplement composition comprising an extract of sea cucumber and an extract of a herb of the genus Cichorium.
Another embodiment of the present invention is a health supplement composition further comprising a sweetener and a preservative.
Further embodiment of the present invention is a method for preparing a health supplement composition comprising dissolving an extract of sea cucumber and an extract of a herb of the genus Cichorium in sterilized reverse osmosis water. One skilled in the art will readily appreciate that the present invention is well adapted to carry out the objects and obtain the ends and advantages mentioned, as well as those inherent therein. The embodiments described herein are not intended as limitations on the scope of the invention.
DETAILED DESCRIPTION OF THE INVENTION
The present invention relates to a health supplement composition. In more particular, the present invention relates to a nutritious composition comprising sea cucumber and chicory, to be taken orally as general health supplement.
Hereinafter, the invention shall be described according to the preferred embodiments of the present invention and by referring to the accompanying description. However, it is to be understood that limiting the description to the preferred embodiments of the invention is merely to facilitate discussion of the present invention and it is envisioned that those skilled in the art may devise various modifications without departing from the scope of the appended claim.
The present invention discloses a health supplement composition comprising an extract of sea cucumber and an extract of a herb of the genus Cichorium.
According to the preferred embodiment of the present invention, the sea cucumber used is selected from the species of Stichopus horrens, Stichopus variegatus,
Stichopus hermanii, Stichopus chloronotus, Stichopus badionotus or Holothuria spp.
In the most preferred embodiment of the present invention, the sea cucumber used in this health supplement composition is Stichopus variegatus. It is one of the several species of golden sea cucumber which is also known as gamat emas. The extract of the sea cucumber is commercially obtained. The dried body parts of sea cucumber, including the body walls, muscles and others are employed to acquire the gamat extract.
Preferably, the sea cucumber is present in an amount of 18% to 22% by weight of the composition. Most preferably, the percentage of sea cucumber in this composition is 20%. As described by the most preferred embodiment of the present invention, 3g of the extract of Stichopus variegatus is required to be dissolved in sterilized reverse osmosis water for acquiring a 15ml gamat solution.
The active compounds contained in Stichopus variegatus possesses a lot of medicinal and nutritional values. The polysaccharide condroition sulphate is capable of reducing athritic pain. In addition, its glycoprotein, fucans and lectins content are also useful for the development of therapeutic drugs for arthritis, cancer or HFV treatments. The active compounds help enhancing blood circulation, reducing high blood pressure, soothing joint inflammation, reducing weariness and providing other therapeutic effects.
The Stichopus variegatus also possesses eicopentaenoic acid (EPA), Docosahexanoic acid (DHA) and vitamins which are crucial for wound healing and anti-aging. Since wound is a discruption of the anatomic structure that responsible for a particular function, treating wound is essential as it is the first root for bacteria and virus infection. A chronic disease condition such as diabetic case could create further complications to the would-healing process. The composition of the present invention is capable of hasten the healing process as it also contains holothurin which helps to enhance the immunity of the body system. The collagen content in this composition also helps in rebuilding and increasing the elasticity of skin tissues.
The sea cucumber extract is anti-thrombotic and helps to reduce the risks of stroke by preventing the arteries from blood clots and blood fat. Besides, it also contains 18 types of amino acids, including asparagic, acid theorine, serine, glutamic acid, praline, phenylalanine, lysine, ammonia, histidine, arginine and others. Some essential minerals such as selenium, calcium and zinc also present in the extract.
In accordance with the preferred embodiment of the present invention, an extract of a herb of the genus Cichorium is employed. Preferably, the herb used is Cichorium intybus. It is a flowering plant generally known as chicory. Chicory is capable of enhancing the growth of probiotics, such as Lactobacillus spp. which are beneficial to the human digestive system. Chicory is also a remedy for dyspnea, loss of appetite, kidney and gall stone problems, intestinal worm and type II diabetes. Being an inulin producer, chicory is deemed as a dietary fibre suitable for the children. According to the preferred embodiment, chicory of the present invention also functions as a natural sweetener and glucose level balancer. With the addition of chicory, the health supplement product of the present invention can also helps in the elimination of intestine worm among the kids.
The extract of Cichorium intybus used is derived from its radix or root which is available in powder form. Preferably, the Cichorium intybus is present in an amount of 1.5% to 2.0% by weight of the composition. Most preferably, the percentage of Cichorium extract in this composition is 1.8%. As described by the most preferred embodiment of the present invention, 0.27g of the extract of Cichorium intybus is dissolved in sterilized reverse osmosis water when a 15ml gamat solution is prepared.
Another embodiment of the present invention is a health supplement composition which further comprises a sweetener and a preservative. According to the preferred embodiment, the sweetener is present in an amount of 0.5% to 1.0% by weight of the composition. Most preferably, the percentage of melon extract in this composition is 0.8%. The preferred sweetener of this health supplement invented is melon extract. The preservative used in the present invention can be sodium benzoate, potassium sorbate or the combination thereof. Preferably, the preservative used in the present invention is a combination of sodium benzoate and potassium sorbate. When a 15ml of gamat solution is prepared, 0.12g of melon extract, 0.039g of sodium benzoate and 0.009g of potassium sorbate are dissolved in sterilized reverse osmosis water together with the extract of sea cucumber as well as the extract of chicory.
Another embodiment of the present invention is a method for preparing a health supplement composition comprising dissolving an extract of sea cucumber and an extract of a herb of the genus Cichorium in sterilized reverse osmosis water.
The method for preparing the health supplement of the present invention is initiated by choosing the raw materials from proper channel. A general quality control scheme is applied to the raw materials, including examination of their colour, pH and sterility. Then, the raw materials, extract of sea cucumber, extract of chicory, sweetener and preservatives, are weighed respectively to obtain an appropriate quantity for a product of gamat.
The reverse osmosis water to be used in the present invention is undergone a double- sterilization process before it is used. The reverse osmosis water is sterilized by ozone and then by ultraviolet to give a bacterial-free solvent for the preparation of the gamat solution. All raw materials are water-based and soluble in this sterilized reverse osmosis water. Finally, the dissolved sea cucumber extract and the additives are subjected to bottling, packaging and labeling.
According to the preferred embodiment of the present invention, the health supplement composition invented is in the form of solution which is golden yellow in colour. The solution is preferably taken orally. Experimental results of the product's effectiveness have shown that the extract of sea cucumber is capable of healing cut in a shorter period when the solution is taken orally than when it is applied on the surface of the cut. The consumption of this health supplement will increase the elasticity of the skin tissue due to their collagen content but will not result in any toxicity in the liver nor kidney. This product is suitable for the consumption of the post-operation patients, mothers after birth, elderlys, patients with menopause problems, premenstrual syndromes or sexual difficulties, type II diabetes, depression, or weariness.
The present disclosure includes as contained in the appended claims, as well as that of the foregoing description. Although this invention has been described in its preferred form with a degree of particularity, it is understood that the present disclosure of the preferred form has been made only by way of example and that numerous changes in the details of construction and the combination and arrangements of parts may be resorted to without departing from the scope of the invention.

Claims

1. A health supplement composition comprising an extract of sea cucumber and an extract of a herb of the genus Cichorium.
2. A composition according to claim 1 further comprising a sweetener and a preservative.
3. A composition according to claim 1 or claim 2, wherein the sea cucumber is of the species of Stichopus horrens, Stichopus variegatus, Stichopus hermanii,
Stichopus chloronotus, Stichopus badionotus or Holothuria spp.
4. A composition according to any one of claims 1 to 3, wherein the sea cucumber is present in an amount of 18% to 22% by weight of the composition.
5. A composition according to any one of claims 1 to 4, wherein the herb is Cichorium intybus,
6. A composition according to any one of claims 1 to 5, wherein the herb is present in an amount of 1.5% to 2.0% by weight of the composition.
7. A composition according to any one of claims 2 to 6, wherein the sweetener is melon extract.
8. A composition according to any one of claims 2 to 7, wherein the sweetener is present in an amount of 0.5% to 1.0% by weight of the composition.
9. A composition according to any one of claims 2 to 8, wherein the preservative is sodium benzoate, potassium sorbate or the combination thereof.
10. A composition according to any one of claims 1 to 9 is in the form of a solution.
11. A method for preparing a health supplement composition comprising dissolving an extract of sea cucumber and an extract of a herb of the genus Cichorium in sterilized reverse osmosis water.
PCT/MY2009/000030 2008-02-15 2009-02-13 Health supplement composition of sea cucumber WO2009102191A1 (en)

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MYPI20080269 2008-02-15

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102919830A (en) * 2012-10-26 2013-02-13 青岛佳日隆海洋食品有限公司 Sea cucumber oral liquid and preparation technology thereof
CN102940245A (en) * 2012-10-26 2013-02-27 青岛佳日隆海洋食品有限公司 Sea cucumber oral liquid and preparation process thereof
CN102940280A (en) * 2012-10-26 2013-02-27 青岛佳日隆海洋食品有限公司 Sea cucumber capsule and preparation process thereof
CN102940247A (en) * 2012-10-26 2013-02-27 青岛佳日隆海洋食品有限公司 Sea cucumber capsule and preparation process thereof
CN104435359A (en) * 2014-12-09 2015-03-25 山东好当家海洋发展股份有限公司 Liver-protecting stichopus japonicus traditional Chinese medicine oral solution and preparation method thereof

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109699537B (en) * 2018-01-11 2021-11-26 海南大学 Breeding method of stichopus japonicus artificial seedlings

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
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CN102940280A (en) * 2012-10-26 2013-02-27 青岛佳日隆海洋食品有限公司 Sea cucumber capsule and preparation process thereof
CN102940247A (en) * 2012-10-26 2013-02-27 青岛佳日隆海洋食品有限公司 Sea cucumber capsule and preparation process thereof
CN102940245B (en) * 2012-10-26 2014-07-09 青岛佳日隆海洋食品有限公司 Sea cucumber oral liquid and preparation process thereof
CN102919830B (en) * 2012-10-26 2014-07-09 青岛佳日隆海洋食品有限公司 Sea cucumber oral liquid and preparation technology thereof
CN102940280B (en) * 2012-10-26 2014-07-09 青岛佳日隆海洋食品有限公司 Sea cucumber capsule and preparation process thereof
CN104435359A (en) * 2014-12-09 2015-03-25 山东好当家海洋发展股份有限公司 Liver-protecting stichopus japonicus traditional Chinese medicine oral solution and preparation method thereof
CN104435359B (en) * 2014-12-09 2019-03-08 山东好当家海洋发展股份有限公司 A kind of protect liver stichopus japonicus traditional Chinese medicine oral liquid and preparation method thereof

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