WO2009041651A1 - 速崩壊性固形製剤 - Google Patents
速崩壊性固形製剤 Download PDFInfo
- Publication number
- WO2009041651A1 WO2009041651A1 PCT/JP2008/067549 JP2008067549W WO2009041651A1 WO 2009041651 A1 WO2009041651 A1 WO 2009041651A1 JP 2008067549 W JP2008067549 W JP 2008067549W WO 2009041651 A1 WO2009041651 A1 WO 2009041651A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- solid preparation
- disintegrating solid
- rapidly disintegrating
- sugar
- rapidly
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Nutrition Science (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Medicinal Preparation (AREA)
Abstract
口腔内の唾液または少量の水の存在下において速やかに崩壊する固形製剤、とりわけ口腔内崩壊性固形製剤として有用な速崩壊性固形製剤を提供する。 具体的には、平均粒子径75μm以上、かつ、溶解速度の速い糖類または糖アルコールをセルロース類で被覆した被覆造粒物を含有する速崩壊性固形製剤、並びに、a)活性成分、b)平均粒子径400μm以上の糖または糖アルコール、c)セルロース類およびd)崩壊剤を含有する速崩壊性固形製剤を提供する。
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP08834316A EP2196221A4 (en) | 2007-09-27 | 2008-09-26 | SOLID PREPARATION WITH QUICK DISINTEGRATION |
US12/733,900 US20100233278A1 (en) | 2007-09-27 | 2008-09-26 | Rapidly disintegrating solid preparation |
JP2009534441A JP5537943B2 (ja) | 2007-09-27 | 2008-09-26 | 速崩壊性固形製剤 |
US13/419,847 US20120171296A1 (en) | 2007-09-27 | 2012-03-14 | Rapidly disintegrating solid preparation |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2007-250920 | 2007-09-27 | ||
JP2007250920 | 2007-09-27 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US13/419,847 Continuation US20120171296A1 (en) | 2007-09-27 | 2012-03-14 | Rapidly disintegrating solid preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2009041651A1 true WO2009041651A1 (ja) | 2009-04-02 |
Family
ID=40511531
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2008/067549 WO2009041651A1 (ja) | 2007-09-27 | 2008-09-26 | 速崩壊性固形製剤 |
Country Status (4)
Country | Link |
---|---|
US (2) | US20100233278A1 (ja) |
EP (1) | EP2196221A4 (ja) |
JP (1) | JP5537943B2 (ja) |
WO (1) | WO2009041651A1 (ja) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010137613A1 (ja) * | 2009-05-28 | 2010-12-02 | 第一三共株式会社 | 貯蔵安定性が改善された固形製剤 |
JP2011213695A (ja) * | 2010-04-02 | 2011-10-27 | Taisho Pharm Ind Ltd | ドネペジル塩酸塩含有口腔内速崩壊錠 |
WO2012005359A1 (ja) * | 2010-07-09 | 2012-01-12 | 帝人ファーマ株式会社 | 口腔内崩壊錠剤 |
JP2014210746A (ja) * | 2013-04-19 | 2014-11-13 | マイクロフーズジャパン株式会社 | 直打用エリスリトール球形顆粒及びその製造方法並びに該エリスリトール顆粒を薬効成分又は栄養成分とともに打錠する製造方法及びその製造方法で得られた錠剤または一般飲食錠菓 |
JP5995284B2 (ja) * | 2010-12-03 | 2016-09-21 | 日本曹達株式会社 | 固形製剤 |
WO2019131411A1 (ja) * | 2017-12-27 | 2019-07-04 | 物産フードサイエンス株式会社 | 口腔内崩壊錠用エリスリトール顆粒およびその製造方法ならびにそれを用いた口腔内崩壊錠 |
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AUPQ899700A0 (en) | 2000-07-25 | 2000-08-17 | Borody, Thomas Julius | Probiotic recolonisation therapy |
AUPS088702A0 (en) * | 2002-03-04 | 2002-03-28 | Borody, Thomas Julius | Electrolyte purgative |
US9308226B2 (en) | 2010-08-04 | 2016-04-12 | Thomas Julius Borody | Compositions for fecal floral transplantation and methods for making and using them and devices for delivering them |
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US9968638B2 (en) | 2011-03-09 | 2018-05-15 | Regents Of The University Of Minnesota | Compositions and methods for transplantation of colon microbiota |
US9719144B2 (en) | 2012-05-25 | 2017-08-01 | Arizona Board Of Regents | Microbiome markers and therapies for autism spectrum disorders |
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CN105307654B (zh) | 2013-04-30 | 2022-06-07 | 托马斯·朱利叶斯·波洛迪 | 用于治疗微生物区系相关的精神病况和疾病的组合物和方法 |
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EP3352773A4 (en) | 2015-09-24 | 2019-03-27 | San Diego State University (SDSU) Foundation DBA San Diego State University Research Foundation | ANTIBACTERIAL AND PROTECTIVE BACTERIOPHAGE FORMULATIONS AND PROCESS FOR THE PREPARATION AND USE THEREOF |
US20170360848A1 (en) | 2016-06-15 | 2017-12-21 | Arizona Board Of Regents On Behalf Of Arizona State University | Methods for treating autism spectrum disorder and associated symptoms |
WO2017217491A1 (ja) * | 2016-06-16 | 2017-12-21 | 東和薬品株式会社 | 口腔内崩壊錠 |
US10849936B2 (en) | 2016-07-01 | 2020-12-01 | Regents Of The University Of Minnesota | Compositions and methods for C. difficile treatment |
US20180036352A1 (en) | 2016-08-03 | 2018-02-08 | Crestovo Holdings Llc | Methods for treating ulcerative colitis |
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US11433102B2 (en) | 2017-04-05 | 2022-09-06 | Finch Therapeutics Holdings Llc | Compositions and methods for treating Parkinson's disease (PD) and related disorders |
CN110996917A (zh) | 2017-05-26 | 2020-04-10 | 克雷斯顿沃控股公司 | 包含基于粪便微生物的治疗剂的冻干组合物及其制造和使用方法 |
AU2018313766A1 (en) | 2017-08-07 | 2020-02-20 | Finch Therapeutics, Inc. | Compositions and methods for maintaining and restoring a healthy gut barrier |
US11166990B2 (en) | 2018-07-13 | 2021-11-09 | Finch Therapeutics Holdings Llc | Methods and compositions for treating ulcerative colitis |
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CN113876730A (zh) * | 2021-10-12 | 2022-01-04 | 合肥远志医药科技开发有限公司 | 一种舒必利制剂及其制备方法 |
CN117652655A (zh) * | 2023-12-06 | 2024-03-08 | 浙江贝灵生物医药有限公司 | 一种闪释辅料及其制备方法和应用 |
Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997047287A1 (fr) | 1996-06-14 | 1997-12-18 | Kyowa Hakko Kogyo Co., Ltd. | Comprime intra-oral a desintegration rapide |
JP2000178183A (ja) * | 1998-12-17 | 2000-06-27 | Lion Corp | 固形製剤及びその製造方法 |
JP2001058944A (ja) | 1999-06-18 | 2001-03-06 | Takeda Chem Ind Ltd | 速崩壊性固形製剤 |
WO2004064810A1 (ja) | 2003-01-21 | 2004-08-05 | Nippon Shinyaku Co., Ltd. | 口腔内速崩性錠剤 |
JP2004315483A (ja) | 2003-02-28 | 2004-11-11 | Towa Yakuhin Kk | 口腔内崩壊錠剤 |
JP2006022040A (ja) * | 2004-07-08 | 2006-01-26 | Towa Yakuhin Kk | 高い安定性を有するシンバスタチン固形製剤 |
JP2007197438A (ja) | 2005-12-28 | 2007-08-09 | Dainippon Sumitomo Pharma Co Ltd | 口腔内速崩壊錠剤 |
JP2007250920A (ja) | 2006-03-17 | 2007-09-27 | Sanyo Electric Co Ltd | 固体電解コンデンサの製造方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69218687T2 (de) * | 1991-07-26 | 1997-07-10 | Mitsubishi Chem Corp | Verfahren zur Herstellung von Erythritolkristallen |
US5607697A (en) * | 1995-06-07 | 1997-03-04 | Cima Labs, Incorporated | Taste masking microparticles for oral dosage forms |
US5958453A (en) * | 1996-10-31 | 1999-09-28 | Takeda Chemical Industries, Ltd. | Solid pharmaceutical preparation with improved buccal disintegrability and/or dissolubility |
DK1561458T3 (da) * | 1998-07-28 | 2010-10-25 | Takeda Pharmaceutical | Hurtigt henfaldende fast middel |
-
2008
- 2008-09-26 EP EP08834316A patent/EP2196221A4/en not_active Withdrawn
- 2008-09-26 WO PCT/JP2008/067549 patent/WO2009041651A1/ja active Application Filing
- 2008-09-26 US US12/733,900 patent/US20100233278A1/en not_active Abandoned
- 2008-09-26 JP JP2009534441A patent/JP5537943B2/ja not_active Expired - Fee Related
-
2012
- 2012-03-14 US US13/419,847 patent/US20120171296A1/en not_active Abandoned
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997047287A1 (fr) | 1996-06-14 | 1997-12-18 | Kyowa Hakko Kogyo Co., Ltd. | Comprime intra-oral a desintegration rapide |
JP2000178183A (ja) * | 1998-12-17 | 2000-06-27 | Lion Corp | 固形製剤及びその製造方法 |
JP2001058944A (ja) | 1999-06-18 | 2001-03-06 | Takeda Chem Ind Ltd | 速崩壊性固形製剤 |
WO2004064810A1 (ja) | 2003-01-21 | 2004-08-05 | Nippon Shinyaku Co., Ltd. | 口腔内速崩性錠剤 |
JP2004315483A (ja) | 2003-02-28 | 2004-11-11 | Towa Yakuhin Kk | 口腔内崩壊錠剤 |
JP2006022040A (ja) * | 2004-07-08 | 2006-01-26 | Towa Yakuhin Kk | 高い安定性を有するシンバスタチン固形製剤 |
JP2007197438A (ja) | 2005-12-28 | 2007-08-09 | Dainippon Sumitomo Pharma Co Ltd | 口腔内速崩壊錠剤 |
JP2007250920A (ja) | 2006-03-17 | 2007-09-27 | Sanyo Electric Co Ltd | 固体電解コンデンサの製造方法 |
Non-Patent Citations (1)
Title |
---|
See also references of EP2196221A4 * |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010137613A1 (ja) * | 2009-05-28 | 2010-12-02 | 第一三共株式会社 | 貯蔵安定性が改善された固形製剤 |
JP2011213695A (ja) * | 2010-04-02 | 2011-10-27 | Taisho Pharm Ind Ltd | ドネペジル塩酸塩含有口腔内速崩壊錠 |
WO2012005359A1 (ja) * | 2010-07-09 | 2012-01-12 | 帝人ファーマ株式会社 | 口腔内崩壊錠剤 |
CN102958514A (zh) * | 2010-07-09 | 2013-03-06 | 帝人制药株式会社 | 口腔内崩解片剂 |
JP5995284B2 (ja) * | 2010-12-03 | 2016-09-21 | 日本曹達株式会社 | 固形製剤 |
JP2014210746A (ja) * | 2013-04-19 | 2014-11-13 | マイクロフーズジャパン株式会社 | 直打用エリスリトール球形顆粒及びその製造方法並びに該エリスリトール顆粒を薬効成分又は栄養成分とともに打錠する製造方法及びその製造方法で得られた錠剤または一般飲食錠菓 |
WO2019131411A1 (ja) * | 2017-12-27 | 2019-07-04 | 物産フードサイエンス株式会社 | 口腔内崩壊錠用エリスリトール顆粒およびその製造方法ならびにそれを用いた口腔内崩壊錠 |
JPWO2019131411A1 (ja) * | 2017-12-27 | 2020-12-10 | 物産フードサイエンス株式会社 | 口腔内崩壊錠用エリスリトール顆粒およびその製造方法ならびにそれを用いた口腔内崩壊錠 |
Also Published As
Publication number | Publication date |
---|---|
JP5537943B2 (ja) | 2014-07-02 |
US20100233278A1 (en) | 2010-09-16 |
US20120171296A1 (en) | 2012-07-05 |
EP2196221A1 (en) | 2010-06-16 |
EP2196221A4 (en) | 2011-12-28 |
JPWO2009041651A1 (ja) | 2011-01-27 |
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