WO2009041651A1 - 速崩壊性固形製剤 - Google Patents

速崩壊性固形製剤 Download PDF

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Publication number
WO2009041651A1
WO2009041651A1 PCT/JP2008/067549 JP2008067549W WO2009041651A1 WO 2009041651 A1 WO2009041651 A1 WO 2009041651A1 JP 2008067549 W JP2008067549 W JP 2008067549W WO 2009041651 A1 WO2009041651 A1 WO 2009041651A1
Authority
WO
WIPO (PCT)
Prior art keywords
solid preparation
disintegrating solid
rapidly disintegrating
sugar
rapidly
Prior art date
Application number
PCT/JP2008/067549
Other languages
English (en)
French (fr)
Inventor
Akiko Ookawa
Yasushi Imada
Yasunari Shinkai
Hideaki Matsumoto
Original Assignee
Mitsubishi Tanabe Pharma Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to JP2007250920 priority Critical
Priority to JP2007-250920 priority
Application filed by Mitsubishi Tanabe Pharma Corporation filed Critical Mitsubishi Tanabe Pharma Corporation
Publication of WO2009041651A1 publication Critical patent/WO2009041651A1/ja

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets

Abstract

 口腔内の唾液または少量の水の存在下において速やかに崩壊する固形製剤、とりわけ口腔内崩壊性固形製剤として有用な速崩壊性固形製剤を提供する。  具体的には、平均粒子径75μm以上、かつ、溶解速度の速い糖類または糖アルコールをセルロース類で被覆した被覆造粒物を含有する速崩壊性固形製剤、並びに、a)活性成分、b)平均粒子径400μm以上の糖または糖アルコール、c)セルロース類およびd)崩壊剤を含有する速崩壊性固形製剤を提供する。
PCT/JP2008/067549 2007-09-27 2008-09-26 速崩壊性固形製剤 WO2009041651A1 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2007250920 2007-09-27
JP2007-250920 2007-09-27

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US12/733,900 US20100233278A1 (en) 2007-09-27 2008-09-26 Rapidly disintegrating solid preparation
EP08834316A EP2196221A4 (en) 2007-09-27 2008-09-26 Rapidly disintegrating solid preparation
JP2009534441A JP5537943B2 (ja) 2007-09-27 2008-09-26 速崩壊性固形製剤
US13/419,847 US20120171296A1 (en) 2007-09-27 2012-03-14 Rapidly disintegrating solid preparation

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US13/419,847 Continuation US20120171296A1 (en) 2007-09-27 2012-03-14 Rapidly disintegrating solid preparation

Publications (1)

Publication Number Publication Date
WO2009041651A1 true WO2009041651A1 (ja) 2009-04-02

Family

ID=40511531

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/067549 WO2009041651A1 (ja) 2007-09-27 2008-09-26 速崩壊性固形製剤

Country Status (4)

Country Link
US (2) US20100233278A1 (ja)
EP (1) EP2196221A4 (ja)
JP (1) JP5537943B2 (ja)
WO (1) WO2009041651A1 (ja)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010137613A1 (ja) * 2009-05-28 2010-12-02 第一三共株式会社 貯蔵安定性が改善された固形製剤
JP2011213695A (ja) * 2010-04-02 2011-10-27 Taisho Pharm Ind Ltd ドネペジル塩酸塩含有口腔内速崩壊錠
WO2012005359A1 (ja) * 2010-07-09 2012-01-12 帝人ファーマ株式会社 口腔内崩壊錠剤
JP2014210746A (ja) * 2013-04-19 2014-11-13 マイクロフーズジャパン株式会社 直打用エリスリトール球形顆粒及びその製造方法並びに該エリスリトール顆粒を薬効成分又は栄養成分とともに打錠する製造方法及びその製造方法で得られた錠剤または一般飲食錠菓
JP5995284B2 (ja) * 2010-12-03 2016-09-21 日本曹達株式会社 固形製剤

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPQ899700A0 (en) 2000-07-25 2000-08-17 Borody, Thomas Julius Probiotic recolonisation therapy
AUPS088702A0 (en) * 2002-03-04 2002-03-28 Borody, Thomas Julius Electrolyte purgative
EP3311825A1 (en) 2010-08-04 2018-04-25 Thomas Julius Borody Compositions for fecal floral transplantation and methods for making and using them
EP2651415A4 (en) 2010-12-13 2014-04-23 Borody Thomas J Gastric and colonic formulations and methods for making and using them
EP3135291A1 (en) 2011-03-09 2017-03-01 Regents Of The University Of Minnesota Compositions and methods for transplantation of colon microbiota
WO2014016671A2 (en) 2012-07-27 2014-01-30 Redhill Biopharma Ltd. Formulations and methods of manufacturing formulations for use in colonic evacuation
WO2016183577A1 (en) 2015-05-14 2016-11-17 Crestovo Llc Compositions for fecal floral transplantation and methods for making and using them and devices for delivering them
US20180036352A1 (en) 2016-08-03 2018-02-08 Crestovo Holdings Llc Methods for treating ulcerative colitis
US10092601B2 (en) 2016-10-11 2018-10-09 Crestovo Holdings Llc Compositions and methods for treating multiple sclerosis and related disorders

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997047287A1 (en) 1996-06-14 1997-12-18 Kyowa Hakko Kogyo Co., Ltd. Intraorally rapidly disintegrable tablet
JP2000178183A (ja) * 1998-12-17 2000-06-27 Lion Corp 固形製剤及びその製造方法
JP2001058944A (ja) 1999-06-18 2001-03-06 Takeda Chem Ind Ltd 速崩壊性固形製剤
WO2004064810A1 (ja) 2003-01-21 2004-08-05 Nippon Shinyaku Co., Ltd. 口腔内速崩性錠剤
JP2004315483A (ja) 2003-02-28 2004-11-11 Towa Yakuhin Kk 口腔内崩壊錠剤
JP2006022040A (ja) * 2004-07-08 2006-01-26 Towa Yakuhin Kk 高い安定性を有するシンバスタチン固形製剤
JP2007197438A (ja) 2005-12-28 2007-08-09 Dainippon Sumitomo Pharma Co Ltd 口腔内速崩壊錠剤
JP2007250920A (ja) 2006-03-17 2007-09-27 Sanyo Electric Co Ltd 固体電解コンデンサの製造方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0525659B1 (en) * 1991-07-26 1997-04-02 Mitsubishi Chemical Corporation Process for preparing erythritol crystals
US5607697A (en) * 1995-06-07 1997-03-04 Cima Labs, Incorporated Taste masking microparticles for oral dosage forms
EP0839526A3 (en) * 1996-10-31 1999-01-07 Takeda Chemical Industries, Ltd. Solid pharmaceutical preparation with fast buccal disintegration or dissolution
CA2525555A1 (en) * 1998-07-28 2000-02-10 Takeda Pharmaceutical Company Limited Rapidly disintegrable solid preparation

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997047287A1 (en) 1996-06-14 1997-12-18 Kyowa Hakko Kogyo Co., Ltd. Intraorally rapidly disintegrable tablet
JP2000178183A (ja) * 1998-12-17 2000-06-27 Lion Corp 固形製剤及びその製造方法
JP2001058944A (ja) 1999-06-18 2001-03-06 Takeda Chem Ind Ltd 速崩壊性固形製剤
WO2004064810A1 (ja) 2003-01-21 2004-08-05 Nippon Shinyaku Co., Ltd. 口腔内速崩性錠剤
JP2004315483A (ja) 2003-02-28 2004-11-11 Towa Yakuhin Kk 口腔内崩壊錠剤
JP2006022040A (ja) * 2004-07-08 2006-01-26 Towa Yakuhin Kk 高い安定性を有するシンバスタチン固形製剤
JP2007197438A (ja) 2005-12-28 2007-08-09 Dainippon Sumitomo Pharma Co Ltd 口腔内速崩壊錠剤
JP2007250920A (ja) 2006-03-17 2007-09-27 Sanyo Electric Co Ltd 固体電解コンデンサの製造方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP2196221A4 *

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010137613A1 (ja) * 2009-05-28 2010-12-02 第一三共株式会社 貯蔵安定性が改善された固形製剤
JP2011213695A (ja) * 2010-04-02 2011-10-27 Taisho Pharm Ind Ltd ドネペジル塩酸塩含有口腔内速崩壊錠
WO2012005359A1 (ja) * 2010-07-09 2012-01-12 帝人ファーマ株式会社 口腔内崩壊錠剤
CN102958514A (zh) * 2010-07-09 2013-03-06 帝人制药株式会社 口腔内崩解片剂
JP5995284B2 (ja) * 2010-12-03 2016-09-21 日本曹達株式会社 固形製剤
JP2014210746A (ja) * 2013-04-19 2014-11-13 マイクロフーズジャパン株式会社 直打用エリスリトール球形顆粒及びその製造方法並びに該エリスリトール顆粒を薬効成分又は栄養成分とともに打錠する製造方法及びその製造方法で得られた錠剤または一般飲食錠菓

Also Published As

Publication number Publication date
JP5537943B2 (ja) 2014-07-02
JPWO2009041651A1 (ja) 2011-01-27
US20100233278A1 (en) 2010-09-16
EP2196221A1 (en) 2010-06-16
EP2196221A4 (en) 2011-12-28
US20120171296A1 (en) 2012-07-05

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