WO2009041381A1 - シリンジ用ポリプロピレン樹脂およびこれを原料として得られるシリンジ並びにプレフィルドシリンジ製剤 - Google Patents

シリンジ用ポリプロピレン樹脂およびこれを原料として得られるシリンジ並びにプレフィルドシリンジ製剤 Download PDF

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Publication number
WO2009041381A1
WO2009041381A1 PCT/JP2008/067074 JP2008067074W WO2009041381A1 WO 2009041381 A1 WO2009041381 A1 WO 2009041381A1 JP 2008067074 W JP2008067074 W JP 2008067074W WO 2009041381 A1 WO2009041381 A1 WO 2009041381A1
Authority
WO
WIPO (PCT)
Prior art keywords
syringe
weight
polypropylene resin
dinsol
dsol
Prior art date
Application number
PCT/JP2008/067074
Other languages
English (en)
French (fr)
Inventor
Takashi Arai
Hiroyuki Uekita
Keita Itakura
Satoshi Hashizume
Original Assignee
Mitsui Chemicals, Inc.
Prime Polymer Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40511266&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=WO2009041381(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Mitsui Chemicals, Inc., Prime Polymer Co., Ltd. filed Critical Mitsui Chemicals, Inc.
Priority to US12/680,319 priority Critical patent/US20100234810A1/en
Priority to KR1020107009200A priority patent/KR101161969B1/ko
Priority to CN200880108405A priority patent/CN101809052A/zh
Priority to EP08834086A priority patent/EP2196483B1/en
Priority to JP2009534314A priority patent/JP5514550B2/ja
Publication of WO2009041381A1 publication Critical patent/WO2009041381A1/ja

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F297/00—Macromolecular compounds obtained by successively polymerising different monomer systems using a catalyst of the ionic or coordination type without deactivating the intermediate polymer
    • C08F297/06—Macromolecular compounds obtained by successively polymerising different monomer systems using a catalyst of the ionic or coordination type without deactivating the intermediate polymer using a catalyst of the coordination type
    • C08F297/08—Macromolecular compounds obtained by successively polymerising different monomer systems using a catalyst of the ionic or coordination type without deactivating the intermediate polymer using a catalyst of the coordination type polymerising mono-olefins
    • C08F297/083—Macromolecular compounds obtained by successively polymerising different monomer systems using a catalyst of the ionic or coordination type without deactivating the intermediate polymer using a catalyst of the coordination type polymerising mono-olefins the monomers being ethylene or propylene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3129—Syringe barrels

Landscapes

  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Health & Medical Sciences (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Graft Or Block Polymers (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Containers Having Bodies Formed In One Piece (AREA)
  • Wrappers (AREA)
  • Injection Moulding Of Plastics Or The Like (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)

Abstract

　本発明は、衛生性、耐熱性および透明性に優れ、低分子量物質の溶出もほとんどないシリンジの原料となる、成形時の気泡発生抑制とロングラン成形性、更には射出成形時のコア金型抜き取り時の傷付抑制の全てを従来成し得なかったレベルで満足したシリンジ用ポリプロピレン樹脂を提供することを目的とする。 　本発明のシリンジ用ポリプロピレン樹脂は、メルトフローレート（ASTM D 1238，230°C、2.16kg荷重）が１０～６０ｇ／１０分であり、室温ｎ－デカンに不溶な部分（Ｄinsol）８５～９７重量％と室温ｎ－デカンに可溶な部分（Dsol）３～１５重量％とから構成され（ただし前記ＤinsolとDsolとの合計は１００重量％である）、前記Ｄinsolおよび前記Dsolが特定の要件を満たすエチレンプロピレンブロック共重合体（Ａ）からなることを特徴としている。
PCT/JP2008/067074 2007-09-28 2008-09-22 シリンジ用ポリプロピレン樹脂およびこれを原料として得られるシリンジ並びにプレフィルドシリンジ製剤 WO2009041381A1 (ja)

Priority Applications (5)

Application Number Priority Date Filing Date Title
US12/680,319 US20100234810A1 (en) 2007-09-28 2008-09-22 Polypropylene resin for syringe, syringe produced from the same as raw material, and prefilled syringe preparation
KR1020107009200A KR101161969B1 (ko) 2007-09-28 2008-09-22 주사기용 폴리프로필렌 수지 및 이것을 원료로 하여 얻어지는 주사기 및 프리필드 주사기 제제
CN200880108405A CN101809052A (zh) 2007-09-28 2008-09-22 注射器用聚丙烯树脂及用其作为原料而得到的注射器和预填充注射器制剂
EP08834086A EP2196483B1 (en) 2007-09-28 2008-09-22 Polypropylene resin for syringe, syringe obtained by using the same as raw material, and pre-filled syringe preparation
JP2009534314A JP5514550B2 (ja) 2007-09-28 2008-09-22 シリンジ用ポリプロピレン樹脂およびこれを原料として得られるシリンジ並びにプレフィルドシリンジ製剤

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007254735 2007-09-28
JP2007-254735 2007-09-28

Publications (1)

Publication Number Publication Date
WO2009041381A1 true WO2009041381A1 (ja) 2009-04-02

Family

ID=40511266

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/067074 WO2009041381A1 (ja) 2007-09-28 2008-09-22 シリンジ用ポリプロピレン樹脂およびこれを原料として得られるシリンジ並びにプレフィルドシリンジ製剤

Country Status (6)

Country Link
US (1) US20100234810A1 (ja)
EP (1) EP2196483B1 (ja)
JP (1) JP5514550B2 (ja)
KR (1) KR101161969B1 (ja)
CN (1) CN101809052A (ja)
WO (1) WO2009041381A1 (ja)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011100648A1 (en) * 2010-02-15 2011-08-18 Mallinckrodt Inc. Syringe products and related methods and uses
JP2015131885A (ja) * 2014-01-10 2015-07-23 日本ポリプロ株式会社 プロピレン−エチレンランダムブロック共重合体およびその製造方法

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120046411A1 (en) 2010-08-20 2012-02-23 Becton, Dickinson And Company Recycled Resin Compositions And Disposable Medical Devices Made Therefrom
US10780228B2 (en) 2012-05-07 2020-09-22 Medline Industries, Inc. Prefilled container systems
CN102764467A (zh) * 2012-07-09 2012-11-07 中国人民解放军第二军医大学 预灌封注射针筒
CN105143279B (zh) * 2013-03-12 2017-10-27 三井化学株式会社 烯烃聚合物的制造方法及烯烃聚合用催化剂
US20160030728A1 (en) * 2014-07-31 2016-02-04 Tekni-Plex, Inc. Extrudable tubing and solvent bonded fitting for delivery of medicinal fluids
CN112451797B (zh) * 2020-11-05 2023-04-18 山东永聚医药科技有限公司 高分子预灌封注射器

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004344423A (ja) * 2003-05-22 2004-12-09 Terumo Corp 注射筒
WO2006068308A1 (ja) * 2004-12-22 2006-06-29 Mitsui Chemicals, Inc. プロピレン系重合体、該重合体を含む組成物及びこれらから得られる成形体
JP2006213800A (ja) * 2005-02-02 2006-08-17 Nipro Corp 薬剤包装用基材、薬剤包装用容器およびこれらを用いた製剤
JP2006212148A (ja) * 2005-02-02 2006-08-17 Nipro Corp 薬剤包装用基材、薬剤包装用容器およびこれらを使用した製剤
WO2007116709A1 (ja) * 2006-03-29 2007-10-18 Mitsui Chemicals, Inc. プロピレン系ランダムブロック共重合体、該共重合体を含む樹脂組成物およびそれからなる成形体

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3195434B2 (ja) * 1991-09-10 2001-08-06 第一製薬株式会社 薬液充填シリンジ製剤
TW272985B (ja) * 1992-09-11 1996-03-21 Hoechst Ag
DE69434709T2 (de) * 1993-06-07 2006-10-19 Mitsui Chemicals, Inc. Propylenelastomere
TW420693B (en) * 1997-04-25 2001-02-01 Mitsui Chemicals Inc Olefin polymerization catalysts, transition metal compounds, and <alpha>-olefin/conjugated diene copolymers
JP4554133B2 (ja) * 1999-10-08 2010-09-29 三井化学株式会社 メタロセン化合物、メタロセン化合物の製造方法、オレフィン重合触媒、ポリオレフィンの製造方法およびポリオレフィン

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004344423A (ja) * 2003-05-22 2004-12-09 Terumo Corp 注射筒
WO2006068308A1 (ja) * 2004-12-22 2006-06-29 Mitsui Chemicals, Inc. プロピレン系重合体、該重合体を含む組成物及びこれらから得られる成形体
JP2006213800A (ja) * 2005-02-02 2006-08-17 Nipro Corp 薬剤包装用基材、薬剤包装用容器およびこれらを用いた製剤
JP2006212148A (ja) * 2005-02-02 2006-08-17 Nipro Corp 薬剤包装用基材、薬剤包装用容器およびこれらを使用した製剤
WO2007116709A1 (ja) * 2006-03-29 2007-10-18 Mitsui Chemicals, Inc. プロピレン系ランダムブロック共重合体、該共重合体を含む樹脂組成物およびそれからなる成形体

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011100648A1 (en) * 2010-02-15 2011-08-18 Mallinckrodt Inc. Syringe products and related methods and uses
CN102844063A (zh) * 2010-02-15 2012-12-26 马林克罗特有限公司 针筒产品及相关的方法和用途
JP2013519453A (ja) * 2010-02-15 2013-05-30 マリンクロッド エルエルシー 注射器製品ならびに関連する方法および使用
CN102844063B (zh) * 2010-02-15 2016-01-20 利贝尔-弗拉施姆有限公司 针筒产品及相关的方法和用途
JP2015131885A (ja) * 2014-01-10 2015-07-23 日本ポリプロ株式会社 プロピレン−エチレンランダムブロック共重合体およびその製造方法

Also Published As

Publication number Publication date
KR20100075965A (ko) 2010-07-05
EP2196483A1 (en) 2010-06-16
JP5514550B2 (ja) 2014-06-04
JPWO2009041381A1 (ja) 2011-01-27
US20100234810A1 (en) 2010-09-16
EP2196483A4 (en) 2011-05-25
CN101809052A (zh) 2010-08-18
EP2196483B1 (en) 2012-10-24
KR101161969B1 (ko) 2012-07-04

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