WO2009037725A1 - Ms/ms型質量分析装置 - Google Patents

Ms/ms型質量分析装置 Download PDF

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Publication number
WO2009037725A1
WO2009037725A1 PCT/JP2007/001010 JP2007001010W WO2009037725A1 WO 2009037725 A1 WO2009037725 A1 WO 2009037725A1 JP 2007001010 W JP2007001010 W JP 2007001010W WO 2009037725 A1 WO2009037725 A1 WO 2009037725A1
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WO
WIPO (PCT)
Prior art keywords
ion
collision cell
gas
ions
conductance
Prior art date
Application number
PCT/JP2007/001010
Other languages
English (en)
French (fr)
Inventor
Hiroto Itoi
Daisuke Okumura
Original Assignee
Shimadzu Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shimadzu Corporation filed Critical Shimadzu Corporation
Priority to PCT/JP2007/001010 priority Critical patent/WO2009037725A1/ja
Priority to JP2009532961A priority patent/JP4957805B2/ja
Priority to US12/678,452 priority patent/US8242437B2/en
Priority to EP07827791.0A priority patent/EP2187204B1/en
Publication of WO2009037725A1 publication Critical patent/WO2009037725A1/ja
Priority to JP2012016332A priority patent/JP5229404B2/ja
Priority to US13/455,228 priority patent/US8698074B2/en

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Classifications

    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/004Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
    • H01J49/0045Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn characterised by the fragmentation or other specific reaction

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  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)

Abstract

 コリジョンセル(20)のイオン入射開口(23)、(25)を2段とすることで、イオン入射側のガスコンダクタンスをイオン出射側のガスコンダクタンスよりも小さくする。このガスコンダクタンスの差により、ガス供給管(31)を通して供給されたCIDガスはコリジョンセル(20)内部で全体的にイオン入射側からイオン出射側に向かうように、つまりイオンの進行方向と同方向に流れる。このため、コリジョンセル(20)内に入射したイオンはCIDガスとの接触により減速するものの、ガス琉の助けを受けてその進行が促進されるので、コリジョンセル(20)内での遅延が軽減される。これにより、目的とするプロダクトイオンの検出感度の低下を回避し、イオンの停滞によるゴーストピークの出現も防止することができる。
PCT/JP2007/001010 2007-09-18 2007-09-18 Ms/ms型質量分析装置 WO2009037725A1 (ja)

Priority Applications (6)

Application Number Priority Date Filing Date Title
PCT/JP2007/001010 WO2009037725A1 (ja) 2007-09-18 2007-09-18 Ms/ms型質量分析装置
JP2009532961A JP4957805B2 (ja) 2007-09-18 2007-09-18 Ms/ms型質量分析装置
US12/678,452 US8242437B2 (en) 2007-09-18 2007-09-18 MS/MS mass spectrometer
EP07827791.0A EP2187204B1 (en) 2007-09-18 2007-09-18 Ms/ms mass spectrometer
JP2012016332A JP5229404B2 (ja) 2007-09-18 2012-01-30 Ms/ms型質量分析装置
US13/455,228 US8698074B2 (en) 2007-09-18 2012-04-25 MS/MS mass spectrometer

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/JP2007/001010 WO2009037725A1 (ja) 2007-09-18 2007-09-18 Ms/ms型質量分析装置

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US13/455,228 Continuation US8698074B2 (en) 2007-09-18 2012-04-25 MS/MS mass spectrometer

Publications (1)

Publication Number Publication Date
WO2009037725A1 true WO2009037725A1 (ja) 2009-03-26

Family

ID=40467558

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2007/001010 WO2009037725A1 (ja) 2007-09-18 2007-09-18 Ms/ms型質量分析装置

Country Status (4)

Country Link
US (2) US8242437B2 (ja)
EP (1) EP2187204B1 (ja)
JP (2) JP4957805B2 (ja)
WO (1) WO2009037725A1 (ja)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014076766A1 (ja) * 2012-11-13 2014-05-22 株式会社島津製作所 タンデム四重極型質量分析装置
WO2014080493A1 (ja) * 2012-11-22 2014-05-30 株式会社島津製作所 タンデム四重極型質量分析装置
US10984998B2 (en) 2017-10-26 2021-04-20 Shimadzu Corporation Mass spectrometer

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8242437B2 (en) * 2007-09-18 2012-08-14 Shimadzu Corporation MS/MS mass spectrometer
GB0723183D0 (en) * 2007-11-23 2008-01-09 Micromass Ltd Mass spectrometer
US20110248157A1 (en) * 2008-10-14 2011-10-13 Masuyuki Sugiyama Mass spectrometer and mass spectrometry method
EP2395538B1 (en) * 2009-02-05 2019-01-02 Shimadzu Corporation Ms/ms mass spectrometer
JP5637311B2 (ja) * 2011-06-28 2014-12-10 株式会社島津製作所 三連四重極型質量分析装置
US9583321B2 (en) 2013-12-23 2017-02-28 Thermo Finnigan Llc Method for mass spectrometer with enhanced sensitivity to product ions
US10699330B2 (en) 2018-11-28 2020-06-30 Capital One Services, Llc System and apparatus for geo-location based data analysis
US11501962B1 (en) 2021-06-17 2022-11-15 Thermo Finnigan Llc Device geometries for controlling mass spectrometer pressures

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05159741A (ja) * 1991-12-05 1993-06-25 Shimadzu Corp 開裂イオン質量分析装置
JPH07201304A (ja) 1993-12-29 1995-08-04 Shimadzu Corp Ms/ms型質量分析装置
JPH08124519A (ja) 1994-10-21 1996-05-17 Shimadzu Corp Ms/ms質量分析装置用データ処理装置
US5847386A (en) 1995-08-11 1998-12-08 Mds Inc. Spectrometer with axial field
JP2003525515A (ja) * 1999-06-11 2003-08-26 パーセプティブ バイオシステムズ,インコーポレイテッド 衝突室中での減衰を伴うタンデム飛行時間型質量分析計およびその使用のための方法
JP2004507875A (ja) * 2000-08-30 2004-03-11 エムディーエス インコーポレイテッド ドゥーイング ビジネス アズ エムディーエス サイエックス 質量分析において反応/衝突セルへのイオン源ガスの進入を防止するための装置及び方法
US6812453B2 (en) 2001-06-25 2004-11-02 Micromass Uk Limited Mass spectrometer

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2765890B2 (ja) * 1988-12-09 1998-06-18 株式会社日立製作所 プラズマイオン源微量元素質量分析装置
US5349186A (en) * 1993-06-25 1994-09-20 The Governors Of The University Of Alberta Electrospray interface for mass spectrometer and method of supplying analyte to a mass spectrometer
US6140638A (en) * 1997-06-04 2000-10-31 Mds Inc. Bandpass reactive collision cell
JPH1151096A (ja) * 1997-07-31 1999-02-23 Toyota Motor Corp 車両用ディスクブレーキにおけるディスクロータの防錆カバー
US6525314B1 (en) * 1999-09-15 2003-02-25 Waters Investments Limited Compact high-performance mass spectrometer
US6800846B2 (en) * 2002-05-30 2004-10-05 Micromass Uk Limited Mass spectrometer
US6781117B1 (en) * 2002-05-30 2004-08-24 Ross C Willoughby Efficient direct current collision and reaction cell
US7034292B1 (en) * 2002-05-31 2006-04-25 Analytica Of Branford, Inc. Mass spectrometry with segmented RF multiple ion guides in various pressure regions
JP2004050875A (ja) * 2002-07-17 2004-02-19 Daihatsu Motor Co Ltd 車両走行制御装置及び制御方法
WO2004083805A2 (en) * 2003-03-19 2004-09-30 Thermo Finnigan Llc Obtaining tandem mass spectrometry data for multiple parent ions in an ion population
US6977371B2 (en) * 2003-06-10 2005-12-20 Micromass Uk Limited Mass spectrometer
EP1676291B1 (en) * 2003-10-20 2013-04-24 Ionwerks, Inc. Ion mobility tof/maldi/ms using drift cell alternating high and low electric field regions
GB2414855A (en) * 2004-03-30 2005-12-07 Thermo Finnigan Llc Ion fragmentation by electron capture
GB0612503D0 (en) * 2006-06-23 2006-08-02 Micromass Ltd Mass spectrometer
GB0613900D0 (en) * 2006-07-13 2006-08-23 Micromass Ltd Mass spectrometer
WO2008044290A1 (fr) * 2006-10-11 2008-04-17 Shimadzu Corporation Spectroscope de masse ms/ms
GB0705730D0 (en) * 2007-03-26 2007-05-02 Micromass Ltd Mass spectrometer
US7868289B2 (en) * 2007-04-30 2011-01-11 Ionics Mass Spectrometry Group Inc. Mass spectrometer ion guide providing axial field, and method
US8080785B2 (en) * 2007-09-10 2011-12-20 Ionic Mass Spectrometry Group High pressure collision cell for mass spectrometer
US8242437B2 (en) * 2007-09-18 2012-08-14 Shimadzu Corporation MS/MS mass spectrometer

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05159741A (ja) * 1991-12-05 1993-06-25 Shimadzu Corp 開裂イオン質量分析装置
JPH07201304A (ja) 1993-12-29 1995-08-04 Shimadzu Corp Ms/ms型質量分析装置
JPH08124519A (ja) 1994-10-21 1996-05-17 Shimadzu Corp Ms/ms質量分析装置用データ処理装置
US5847386A (en) 1995-08-11 1998-12-08 Mds Inc. Spectrometer with axial field
JPH11510946A (ja) * 1995-08-11 1999-09-21 エムディーエス ヘルス グループ リミテッド 軸電界を有する分光計
JP2003525515A (ja) * 1999-06-11 2003-08-26 パーセプティブ バイオシステムズ,インコーポレイテッド 衝突室中での減衰を伴うタンデム飛行時間型質量分析計およびその使用のための方法
JP2004507875A (ja) * 2000-08-30 2004-03-11 エムディーエス インコーポレイテッド ドゥーイング ビジネス アズ エムディーエス サイエックス 質量分析において反応/衝突セルへのイオン源ガスの進入を防止するための装置及び方法
US6812453B2 (en) 2001-06-25 2004-11-02 Micromass Uk Limited Mass spectrometer

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP2187204A4 *

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014076766A1 (ja) * 2012-11-13 2014-05-22 株式会社島津製作所 タンデム四重極型質量分析装置
JP5892258B2 (ja) * 2012-11-13 2016-03-23 株式会社島津製作所 タンデム四重極型質量分析装置
JPWO2014076766A1 (ja) * 2012-11-13 2016-09-08 株式会社島津製作所 タンデム四重極型質量分析装置
WO2014080493A1 (ja) * 2012-11-22 2014-05-30 株式会社島津製作所 タンデム四重極型質量分析装置
US9269551B2 (en) 2012-11-22 2016-02-23 Shimadzu Corporation Tandem quadrupole mass spectrometer
JP6004002B2 (ja) * 2012-11-22 2016-10-05 株式会社島津製作所 タンデム四重極型質量分析装置
US9761432B2 (en) 2012-11-22 2017-09-12 Shimadzu Corporation Tandem quadrupole mass spectrometer
US10984998B2 (en) 2017-10-26 2021-04-20 Shimadzu Corporation Mass spectrometer

Also Published As

Publication number Publication date
JP2012094543A (ja) 2012-05-17
US20120205536A1 (en) 2012-08-16
JPWO2009037725A1 (ja) 2010-12-24
EP2187204A4 (en) 2013-07-10
JP5229404B2 (ja) 2013-07-03
US8242437B2 (en) 2012-08-14
EP2187204B1 (en) 2017-05-17
US20100288922A1 (en) 2010-11-18
JP4957805B2 (ja) 2012-06-20
US8698074B2 (en) 2014-04-15
EP2187204A1 (en) 2010-05-19

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