WO2009037394A3 - DERIVES DE 6-CYCLOAMINO-S-(PYRIDAZIN-YL)IMIDAZO[1,2-b]-PYRIDAZINE, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE. - Google Patents
DERIVES DE 6-CYCLOAMINO-S-(PYRIDAZIN-YL)IMIDAZO[1,2-b]-PYRIDAZINE, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE. Download PDFInfo
- Publication number
- WO2009037394A3 WO2009037394A3 PCT/FR2008/001057 FR2008001057W WO2009037394A3 WO 2009037394 A3 WO2009037394 A3 WO 2009037394A3 FR 2008001057 W FR2008001057 W FR 2008001057W WO 2009037394 A3 WO2009037394 A3 WO 2009037394A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- optionally substituted
- cycloamino
- pyridazin
- imidazo
- pyridazine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/5025—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Anesthesiology (AREA)
- Pain & Pain Management (AREA)
- Addiction (AREA)
- Psychology (AREA)
- Hematology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
Priority Applications (11)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES08831515T ES2429765T3 (es) | 2007-07-19 | 2008-07-18 | 6-Cicloamino-S-(piridazin-il)imidazo[1,2-B]-piridazina y sus derivados, su preparación y su aplicación en terapéutica |
JP2010516539A JP5431319B2 (ja) | 2007-07-19 | 2008-07-18 | 6−シクロアミノ−3−(ピリダジン−4−イル)イミダゾ[1,2−b]−ピリダジンおよびこれらの誘導体、これらの調製および治療上の用途 |
EP08831515.5A EP2178879B1 (fr) | 2007-07-19 | 2008-07-18 | DERIVES DE 6-CYCLOAMINO-S-(PYRIDAZIN-YL)IMIDAZO[1,2-b]-PYRIDAZINE, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE. |
CN200880103986A CN101784552A (zh) | 2007-07-19 | 2008-07-18 | 6-环氨基-3-(哒嗪-4-基)咪唑并[1,2-b]哒嗪的衍生物、其制备和其治疗学用途 |
EA201070161A EA016376B1 (ru) | 2007-07-19 | 2008-07-18 | ПРОИЗВОДНЫЕ 6-ЦИКЛОАМИНО-3-(ПИРИДАЗИН-4-ИЛ)ИМИДАЗО[1,2-b]ПИРИДАЗИНА, ИХ ПОЛУЧЕНИЕ И ИХ ПРИМЕНЕНИЕ В ТЕРАПИИ |
CA2693116A CA2693116A1 (fr) | 2007-07-19 | 2008-07-18 | Derives de 6-cycloamino-3-(pyridazin-4-yl)imidazo[1,2-b]-pyridazine, leur preparation et leur application en therapeutique |
NZ582683A NZ582683A (en) | 2007-07-19 | 2008-07-18 | 6-cycloamino-s-(pyridazin-4-yl)imidazo[1,2-b]-pyridazine and derivatives thereof preparation and therapeutic application thereof |
BRPI0814510-5A2A BRPI0814510A2 (pt) | 2007-07-19 | 2008-07-18 | Derivados de 6-cicloamino-3-(piridazin-4-il)imidazol[1,2-b]-piridazina, sua preparação e sua aplicação em terapêutica |
AU2008300449A AU2008300449A1 (en) | 2007-07-19 | 2008-07-18 | 6-cycloamino-s-(pyridazin-4-yl)imidazo[1,2-b]-pyridazine and derivatives thereof preparation and therapeutic application thereof |
US12/685,030 US8455491B2 (en) | 2007-07-19 | 2010-01-11 | 6-cycloamino-3-(pyridazin-4-yl)imidazo[1,2-b]pyridazine and derivatives and pharmaceutical compositions comprising the same |
US13/887,845 US9108971B2 (en) | 2007-07-19 | 2013-05-06 | 6-cycloamino-3-(pyridazin-4-yl)imidazo[1,2-b]-pyridazine and derivatives thereof preparation and therapeutic application thereof |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US95071107P | 2007-07-19 | 2007-07-19 | |
US60/950,711 | 2007-07-19 | ||
FR0705224A FR2918986B1 (fr) | 2007-07-19 | 2007-07-19 | Derives de 6-cycloamino-3-(pyridazin-4-yl)imidazo[1,2-b]- pyridazine, leur preparation et leur application en therapeutique |
FR0705224 | 2007-07-19 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US12/685,030 Continuation US8455491B2 (en) | 2007-07-19 | 2010-01-11 | 6-cycloamino-3-(pyridazin-4-yl)imidazo[1,2-b]pyridazine and derivatives and pharmaceutical compositions comprising the same |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2009037394A2 WO2009037394A2 (fr) | 2009-03-26 |
WO2009037394A3 true WO2009037394A3 (fr) | 2009-06-18 |
Family
ID=39183122
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/FR2008/001057 WO2009037394A2 (fr) | 2007-07-19 | 2008-07-18 | DERIVES DE 6-CYCLOAMINO-S-(PYRIDAZIN-YL)IMIDAZO[1,2-b]-PYRIDAZINE, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE. |
Country Status (22)
Country | Link |
---|---|
US (2) | US8455491B2 (fr) |
EP (1) | EP2178879B1 (fr) |
JP (1) | JP5431319B2 (fr) |
KR (1) | KR20100041771A (fr) |
CN (1) | CN101784552A (fr) |
AR (1) | AR069272A1 (fr) |
AU (1) | AU2008300449A1 (fr) |
BR (1) | BRPI0814510A2 (fr) |
CA (1) | CA2693116A1 (fr) |
CL (1) | CL2008002138A1 (fr) |
CO (1) | CO6290690A2 (fr) |
EA (1) | EA016376B1 (fr) |
ES (1) | ES2429765T3 (fr) |
FR (1) | FR2918986B1 (fr) |
MA (1) | MA31616B1 (fr) |
NZ (1) | NZ582683A (fr) |
PA (1) | PA8789901A1 (fr) |
PE (1) | PE20090493A1 (fr) |
TW (1) | TW200914456A (fr) |
UY (1) | UY31236A1 (fr) |
WO (1) | WO2009037394A2 (fr) |
ZA (1) | ZA201001214B (fr) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8846675B2 (en) | 2007-07-19 | 2014-09-30 | Cymabay Therapeutics, Inc. | N-linked heterocyclic receptor agonists for the treatment of diabetes and metabolic disorders |
US8921350B2 (en) | 2006-12-28 | 2014-12-30 | Cymabay Therapeutics, Inc. | Heterocyclic receptor agonists for the treatment of diabetes and metabolic disorders |
US9150567B2 (en) | 2009-10-01 | 2015-10-06 | Cymabay Therapeutics, Inc. | Substituted tetrazol-1-yl-phenoxymethyl-thiazol-2-yl-piperidinyl-pyrimidine salts |
US9241924B2 (en) | 2010-06-23 | 2016-01-26 | Cymabay Therapeutics, Inc. | Compositions of 5-ethyl-2-{4-[4-(4-tetrazol-1-yl-phenoxymethyl)-thiazol-2-yl]-piperidin-1-yl}-pyrimidine |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7868001B2 (en) * | 2007-11-02 | 2011-01-11 | Hutchison Medipharma Enterprises Limited | Cytokine inhibitors |
FR2939134A1 (fr) * | 2008-12-01 | 2010-06-04 | Sanofi Aventis | Derives de 6-cycloamino-3-(1h-pyrrolo°2,3-b!pyridin-4-yl) imidazo°1,2-b!-pyridazine, leur preparation et leur application en therapeutique |
FR2940284B1 (fr) * | 2008-12-19 | 2011-02-18 | Sanofi Aventis | Derives de 6-cycloamino-2,3-di-pyridinyl-imidazo°1,2-b!- pyridazine,leur preparation et leur application en therapeutique |
FR2940285A1 (fr) | 2008-12-19 | 2010-06-25 | Sanofi Aventis | Derives de 6-cycloamino-2-thienyl-3-(pyridin-4-yl)imidazo °1,2-b!-pyridazine et 6-cycloamino-2-furanyl-3- (pyridin-4-yl)imidazo°1,2-b!-pyridazine, leur preparation et leur application en therapeutique |
US9062044B2 (en) | 2009-10-23 | 2015-06-23 | Janssen Pharmaceutica Nv | Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators |
MX2012004753A (es) | 2009-10-23 | 2012-09-07 | Janssen Pharmaceutica Nv | Octahidropirrolo[3,4-c]pirrolos disustituidos como moduladores del receptor de orexina. |
EP2491034B1 (fr) | 2009-10-23 | 2013-12-18 | Janssen Pharmaceutica, N.V. | Composés hétérocycliques condensés en tant que modulateurs de récepteur d'orexine |
EP2493889B1 (fr) | 2009-10-30 | 2017-09-06 | Janssen Pharmaceutica, N.V. | Dérivés d'imidazo[1,2-b]pyridazine et leur utilisation en tant qu'inhibiteurs pde10 |
AR080754A1 (es) | 2010-03-09 | 2012-05-09 | Janssen Pharmaceutica Nv | Derivados de imidazo (1,2-a) pirazina y su uso como inhibidores de pde10 |
RU2562833C2 (ru) * | 2010-08-09 | 2015-09-10 | НБ Хелс Лаборатори Ко. Лтд. | Ингибитор казеинкиназы 1 дельта и казеинкиназы 1 е |
WO2012080729A2 (fr) | 2010-12-14 | 2012-06-21 | Electrophoretics Limited | Inhibiteurs de caséine kinase 1δ (ck1δ) |
WO2012145581A1 (fr) | 2011-04-20 | 2012-10-26 | Janssen Pharmaceutica Nv | Octahydropyrrolo [3,4-c] pyrroles disubstitués utilisés comme modulateurs du récepteur de l'orexine |
EA027418B1 (ru) | 2011-06-27 | 2017-07-31 | Янссен Фармацевтика Нв | ПРОИЗВОДНЫЕ 1-АРИЛ-4-МЕТИЛ[1,2,4]ТРИАЗОЛО[4,3-a]ХИНОКСАЛИНА, ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ НА ИХ ОСНОВЕ, СПОСОБЫ ПОЛУЧЕНИЯ И ПРИМЕНЕНИЯ ИХ, ПРОМЕЖУТОЧНЫЕ СОЕДИНЕНИЯ |
CA2872216C (fr) | 2012-06-26 | 2021-07-20 | Janssen Pharmaceutica Nv | Combinaisons comprenant des inhibiteurs de la pde 2 tels que des composes 1-aryl-4-methyl-[1,2,4]triazolo [4,3-a]-quinoxaline et des inhibiteurs de la pde 10 pour utilisation dans le traitement de troublesneurologiques ou metaboliques |
US9550784B2 (en) | 2012-07-09 | 2017-01-24 | Beerse Pharmaceutica NV | Inhibitors of phosphodiesterase 10 enzyme |
US9556179B2 (en) | 2012-12-21 | 2017-01-31 | Bristol-Myers Squibb Company | Substituted imidazoles as casein kinase 1 D/E inhibitors |
EP2935272B1 (fr) * | 2012-12-21 | 2017-02-22 | Bristol-Myers Squibb Company | Pyrazole imidazopyrazines substitues par pyrazole comme inhibiteurs de casein kinase 1 d/e |
GB201321734D0 (en) * | 2013-12-09 | 2014-01-22 | Ucb Pharma Sa | Therapeutic Agents |
EP3091982B1 (fr) * | 2014-01-09 | 2019-04-17 | Intra-Cellular Therapies, Inc. | Composés organiques |
MA43817B1 (fr) | 2016-03-10 | 2022-04-29 | Janssen Pharmaceutica Nv | Méthodes de traitement de la dépression à l'aide d'antagonistes de récepteurs de l'orexine-2 |
WO2018026890A1 (fr) | 2016-08-03 | 2018-02-08 | Cymabay Therapeutics | Composés d'aryle d'oxyméthylène pour le traitement de maladies gastro-intestinales inflammatoires ou de troubles gastro-intestinaux |
KR102007135B1 (ko) | 2017-03-20 | 2019-08-02 | 포르마 세라퓨틱스 인크. | 피루베이트 키나제 (pkr) 활성화제로서의 피롤로피롤 조성물 |
CA3090385A1 (fr) | 2018-02-05 | 2019-08-08 | Alkermes, Inc. | Composes pour le traitement de la douleur |
CN113166060B (zh) | 2018-09-19 | 2024-01-09 | 诺沃挪第克健康护理股份公司 | 用丙酮酸激酶激活化合物治疗镰状细胞病 |
JP7450610B2 (ja) | 2018-09-19 | 2024-03-15 | ノヴォ・ノルディスク・ヘルス・ケア・アーゲー | ピルビン酸キナーゼrの活性化 |
TW202112368A (zh) | 2019-06-13 | 2021-04-01 | 荷蘭商法西歐知識產權股份有限公司 | 用於治療有關dux4表現之疾病的抑制劑組合 |
US20230192699A1 (en) * | 2020-03-27 | 2023-06-22 | Gritscience Biopharmaceuticals Co., Ltd. | Compounds as casein kinase inhibitors |
WO2021190616A1 (fr) * | 2020-03-27 | 2021-09-30 | Gritscience Biopharmaceuticals Co., Ltd. | Procédés d'inhibition de caséine kinases |
US11939328B2 (en) | 2021-10-14 | 2024-03-26 | Incyte Corporation | Quinoline compounds as inhibitors of KRAS |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1989001333A1 (fr) * | 1987-08-07 | 1989-02-23 | The Australian National University | IMIDAZO[1,2-b]PYRIDAZINES |
WO2005080355A1 (fr) * | 2004-02-12 | 2005-09-01 | Neurogen Corporation | Imidazo-pyridazines, triazolo-pyridazines et ligands associes des recepteurs de benzodiazepine |
WO2007009773A1 (fr) * | 2005-07-21 | 2007-01-25 | Novartis Ag | Derives de pyrazolo[1,5a]pyrimidin-7-yl-amine utilises en tant qu'inhibiteurs des proteines kinases |
WO2007013673A1 (fr) * | 2005-07-29 | 2007-02-01 | Astellas Pharma Inc. | Hétérocycles fusionnés en tant qu’inhibiteurs de lck |
WO2007025540A2 (fr) * | 2005-09-02 | 2007-03-08 | Bayer Schering Pharma Aktiengesellschaft | Imidazo[1,2b]pyridazines substituees constituant des inhibiteurs de kinases, leur production et leur utilisation comme medicaments |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2375450C (fr) | 1999-06-08 | 2009-04-28 | Aventis Pharmaceuticals Inc. | Methodes de criblage visant la modification des proteines du rythme circadien |
CN100439367C (zh) | 2003-12-11 | 2008-12-03 | 安万特药物公司 | 作为酪蛋白激酶Iε抑制剂的取代的1H-吡咯并[3,2-b、3,2-c和2,3-c]吡啶-2-甲酰胺以及相关类似物 |
-
2007
- 2007-07-19 FR FR0705224A patent/FR2918986B1/fr active Active
-
2008
- 2008-07-15 PA PA20088789901A patent/PA8789901A1/es unknown
- 2008-07-17 PE PE2008001220A patent/PE20090493A1/es not_active Application Discontinuation
- 2008-07-17 UY UY31236A patent/UY31236A1/es not_active Application Discontinuation
- 2008-07-17 TW TW097127189A patent/TW200914456A/zh unknown
- 2008-07-18 EA EA201070161A patent/EA016376B1/ru not_active IP Right Cessation
- 2008-07-18 CA CA2693116A patent/CA2693116A1/fr not_active Abandoned
- 2008-07-18 CL CL2008002138A patent/CL2008002138A1/es unknown
- 2008-07-18 CN CN200880103986A patent/CN101784552A/zh active Pending
- 2008-07-18 BR BRPI0814510-5A2A patent/BRPI0814510A2/pt not_active IP Right Cessation
- 2008-07-18 NZ NZ582683A patent/NZ582683A/en not_active IP Right Cessation
- 2008-07-18 AU AU2008300449A patent/AU2008300449A1/en not_active Abandoned
- 2008-07-18 WO PCT/FR2008/001057 patent/WO2009037394A2/fr active Application Filing
- 2008-07-18 AR ARP080103097A patent/AR069272A1/es unknown
- 2008-07-18 ES ES08831515T patent/ES2429765T3/es active Active
- 2008-07-18 JP JP2010516539A patent/JP5431319B2/ja not_active Expired - Fee Related
- 2008-07-18 EP EP08831515.5A patent/EP2178879B1/fr active Active
- 2008-07-18 KR KR1020107001087A patent/KR20100041771A/ko not_active Application Discontinuation
-
2010
- 2010-01-11 US US12/685,030 patent/US8455491B2/en not_active Expired - Fee Related
- 2010-01-19 CO CO10004823A patent/CO6290690A2/es not_active Application Discontinuation
- 2010-02-17 MA MA32629A patent/MA31616B1/fr unknown
- 2010-02-19 ZA ZA2010/01214A patent/ZA201001214B/en unknown
-
2013
- 2013-05-06 US US13/887,845 patent/US9108971B2/en not_active Expired - Fee Related
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1989001333A1 (fr) * | 1987-08-07 | 1989-02-23 | The Australian National University | IMIDAZO[1,2-b]PYRIDAZINES |
WO2005080355A1 (fr) * | 2004-02-12 | 2005-09-01 | Neurogen Corporation | Imidazo-pyridazines, triazolo-pyridazines et ligands associes des recepteurs de benzodiazepine |
WO2007009773A1 (fr) * | 2005-07-21 | 2007-01-25 | Novartis Ag | Derives de pyrazolo[1,5a]pyrimidin-7-yl-amine utilises en tant qu'inhibiteurs des proteines kinases |
WO2007013673A1 (fr) * | 2005-07-29 | 2007-02-01 | Astellas Pharma Inc. | Hétérocycles fusionnés en tant qu’inhibiteurs de lck |
WO2007025540A2 (fr) * | 2005-09-02 | 2007-03-08 | Bayer Schering Pharma Aktiengesellschaft | Imidazo[1,2b]pyridazines substituees constituant des inhibiteurs de kinases, leur production et leur utilisation comme medicaments |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8921350B2 (en) | 2006-12-28 | 2014-12-30 | Cymabay Therapeutics, Inc. | Heterocyclic receptor agonists for the treatment of diabetes and metabolic disorders |
US8975258B2 (en) | 2006-12-28 | 2015-03-10 | Cymabay Therapeutics, Inc. | Heterocyclic receptor agonists for the treatment of diabetes and metabolic disorders |
US8846675B2 (en) | 2007-07-19 | 2014-09-30 | Cymabay Therapeutics, Inc. | N-linked heterocyclic receptor agonists for the treatment of diabetes and metabolic disorders |
US9150567B2 (en) | 2009-10-01 | 2015-10-06 | Cymabay Therapeutics, Inc. | Substituted tetrazol-1-yl-phenoxymethyl-thiazol-2-yl-piperidinyl-pyrimidine salts |
US9241924B2 (en) | 2010-06-23 | 2016-01-26 | Cymabay Therapeutics, Inc. | Compositions of 5-ethyl-2-{4-[4-(4-tetrazol-1-yl-phenoxymethyl)-thiazol-2-yl]-piperidin-1-yl}-pyrimidine |
Also Published As
Publication number | Publication date |
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FR2918986A1 (fr) | 2009-01-23 |
JP2010533686A (ja) | 2010-10-28 |
UY31236A1 (es) | 2009-03-02 |
US20100152157A1 (en) | 2010-06-17 |
CL2008002138A1 (es) | 2009-10-23 |
ZA201001214B (en) | 2011-05-25 |
NZ582683A (en) | 2011-07-29 |
CO6290690A2 (es) | 2011-06-20 |
CA2693116A1 (fr) | 2009-03-26 |
US20130245023A1 (en) | 2013-09-19 |
PA8789901A1 (es) | 2009-02-09 |
FR2918986B1 (fr) | 2009-09-04 |
EA016376B1 (ru) | 2012-04-30 |
KR20100041771A (ko) | 2010-04-22 |
AU2008300449A1 (en) | 2009-03-26 |
CN101784552A (zh) | 2010-07-21 |
BRPI0814510A2 (pt) | 2015-02-03 |
WO2009037394A2 (fr) | 2009-03-26 |
TW200914456A (en) | 2009-04-01 |
US8455491B2 (en) | 2013-06-04 |
US9108971B2 (en) | 2015-08-18 |
PE20090493A1 (es) | 2009-05-27 |
EP2178879A2 (fr) | 2010-04-28 |
EA201070161A1 (ru) | 2010-08-30 |
EP2178879B1 (fr) | 2013-07-03 |
AR069272A1 (es) | 2010-01-13 |
ES2429765T3 (es) | 2013-11-15 |
MA31616B1 (fr) | 2010-08-02 |
JP5431319B2 (ja) | 2014-03-05 |
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