WO2007111386A1 - Cathéter de traitement pour un cancer du poumon et méthode de traitement d'un cancer du poumon - Google Patents

Cathéter de traitement pour un cancer du poumon et méthode de traitement d'un cancer du poumon Download PDF

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Publication number
WO2007111386A1
WO2007111386A1 PCT/JP2007/057513 JP2007057513W WO2007111386A1 WO 2007111386 A1 WO2007111386 A1 WO 2007111386A1 JP 2007057513 W JP2007057513 W JP 2007057513W WO 2007111386 A1 WO2007111386 A1 WO 2007111386A1
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WO
WIPO (PCT)
Prior art keywords
shaft
lung cancer
cancer treatment
catheter
tip
Prior art date
Application number
PCT/JP2007/057513
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English (en)
Japanese (ja)
Inventor
Kenji Tsushima
Tadatsugu Onuma
Original Assignee
Shinshu University
Japan Lifeline Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shinshu University, Japan Lifeline Co., Ltd. filed Critical Shinshu University
Publication of WO2007111386A1 publication Critical patent/WO2007111386A1/fr

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • A61B18/1492Probes or electrodes therefor having a flexible, catheter-like structure, e.g. for heart ablation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00541Lung or bronchi
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636Sensing and controlling the application of energy
    • A61B2018/00773Sensed parameters
    • A61B2018/00791Temperature

Definitions

  • the present invention relates to a lung cancer treatment catheter. More specifically, the present invention relates to a lung cancer treatment catheter that can be delivered to the bronchus, placed in a jigsaw Pf under observation in combination with an internal fistula, and capable of cauterizing cancer cells by high-frequency energization.
  • the present invention relates to a method for treating vaginal cancer. Background
  • Lung cancer occurs when cells in the trachea, bronchus, and alveoli lose their normal function and increase. Cancer grows by destroying the surrounding paper organs and spreads to other) ⁇ s, forming many moons. The number of people with flf cancer is increasing worldwide. The number of deaths from lung cancer in Japan in 1999 was about 52,000, but this is expected to increase in the future.
  • the lunar cancer screening is generally performed by chest x-ray suppression and sputum cytology, but: X-ray tomography of the lung called helical CT has become widespread, and smaller vaginal cancer has been discovered. Talk. Shelf Moon F (F cancer is an effective treatment method for cancer. For example, the 5-year survival rate of stage I month summary is said to be 70%. Let's go.
  • ⁇ Acupuncture is a treatment in which a needle is pierced into a crest and cauterized;
  • With the i3 ⁇ 4 sensor at the tip of the needle, it can be controlled to control bleeding Since it can be repeated repeatedly with little risk, a therapeutic effect can be expected even for a large ffl3 ⁇ 4.
  • the needle itself is hard and lacks flexibility, it cannot be used for long and wrinkled folds such as blood vessels. Disclosure of the invention
  • An object of the present invention is to provide a lung cancer treatment catheter that can reach the bronchial shrimp, and can be placed under treatment in combination with internal fibrils, and can treat cancer cells by high-frequency energization. Is.
  • the present inventors penetrated a catheter having a tip heel into the inner neck to reach the tumor in the bronchial region, and outside the patient's body.
  • By inductively heating the affected area in the high-frequency electric field consisting of the installed anti-protrusion and the tip of the catheter it is possible to safely and reliably produce monthly cells;
  • the present invention has been made based on the findings.
  • the Shore hardness of Tatsumi Deistano 1 ⁇ 3 ⁇ 4 is 2 0-6 5 HSD
  • the ffflB proximal part has a Shore hardness of 40 to 80 HSD (1) to (4) or a vaginal cancer treatment catheter according to item 1,
  • a lung cancer treatment catheter equipped with a catheter is passed through an endoscope to reach the end of the bronchial region, and the affected part is induction heated by applying a high frequency m between the opposite side of the patient's body and Satoshi Tsutomu Treatment of acupuncture cancer with ablation of ablating cancer cells; ⁇
  • Fig. 1 is an example of an endoscope used in combination with the monthly therapy catheter of the present invention.
  • the # 1 view and the distal end of the endoscope are shown! 3 ⁇ 4 view, Fig. 2 ⁇ : Bfl3 ⁇ 4) S, side view and schematic cross-sectional view of 3 ⁇ 4 of therapeutic power, and Fig. Fig. 4,
  • Fig. 4 is an explanatory view of the treatment using the vaginal cancer treatment catheter of the present invention
  • Fig. 5 shows the distribution in the body of the subject
  • Fig. 6 shows the distribution of the subject
  • Fig. 6 shows the catheter of the present invention
  • reference numeral 1 is an operation
  • 2 is an insertion port
  • 4 is an opening
  • 5 and 6 are light distribution lenses
  • 7 is a condenser lens
  • 8 is an operation unit
  • 9 is a tip H ⁇
  • 1 0 is shaft
  • 1 0 a is daistano V3 ⁇ 45
  • 1 0 b is proxy mano ⁇
  • 1 1 is lead
  • 1 2 sensor
  • 1 3 is solder
  • 1 4 is channel
  • 1 6 is light guide
  • 1 7 is CCD
  • 1 8 is ⁇ 3 line
  • 1 9 is thread tube
  • 2 0 drain pipe
  • 2 1 is subject
  • 2 2 is CT scanning device
  • 2 3 is bed
  • 2 4 is endoscope
  • 2 5 is internal Endoscopic image monitor
  • 26 is a catheter
  • 27 is a CT image monitor
  • 28 is a CT image monitor
  • the lunar therapeutic power Tetenole of the present invention is a force Tetenole that is thinned in combination with the inner part in the treatment of lunar cancer, with manipulation at the proximal end (pro X ima 1) and X-rays at itf3 ⁇ 4 (dista 1). It has a tip ⁇ composed of a non-conductive material, and ⁇ and ⁇ are connected by a shaft with at least one channel, and the shaft position 3 ⁇ 4 ⁇ rule flexible bend and the proximal end rule Oka I ⁇
  • the shaft is made up of the Oka I part, and the shaft has a lead wire that transmits high-frequency energy to the tip, and a fig sensor that uses a strict slogan and power manipulation, and cooling leaks inside the channel.
  • the catheter is equipped with a high-frequency energization for tip comfort.
  • Therapeutic power Tetenor can be used not only for the treatment of cancer, which is a malignant tumor of the lung, but also for the treatment of good life in Tsukiichi.
  • the vaginal cancer treatment catheter of the present invention can be used particularly in combination with the trachea.
  • the TO in combination with the lung cancer treatment catheter of the present invention includes a finer scope using glass finer, an electronic inner surface using CCD, and the like. Among these, inside the electronic! ⁇ Can be preferably used.
  • Fig. 1 is a # 4 view of an aspect of an electronic net shelved in combination with the monthly summary treatment catheter of the present invention and a portion of the distant view thereof.
  • the electronic interior of the main body is provided with the operation ⁇ 1 and the insertion port 2 force s at the proximal end, and the remote operation dial 3 force s for operation.
  • an aperture 4 At the remote end, an aperture 4, two light distribution lenses 5, 6 and a condenser lens 7 are provided.
  • the system consists of a combination of an electronic network, a light source processor device and a monitor.
  • the electronic housing has a body insertion portion, a control lever 151, a connection cable, and a connector (not shown).
  • a condensing lens 7 and an opening 4 are provided at the distal end of the body cavity insertion portion.
  • C CD 17 arranged opposite to the condenser lens 7, ⁇ BHl 8 connected to the C CD 17, and light distribution lenses 5 and 6 with their tips at the ends.
  • Opposed light guides 1 6 forces S are provided.
  • channel 1 4 force S connected to opening 4 is formed.
  • a curved tree (not shown) force S is formed.
  • connection cable is connected to the surface opposite to the operation dial 3 of the remote control dial 5 [5 1].
  • Connection cable rules include connectors Force S is provided.
  • the light guide 16 and wiring 18 are passed through the connection cable.
  • the wiring 18 is connected to a terminal provided on the connector.
  • the light guide 16 faces the window provided in the connector.
  • the original processor unit is composed of hard and video processor units. It is provided on the side of the crane that can be connected to the connector for electronic endoscopy.
  • the apparatus is an apparatus that emits visible light, ultraviolet light, and the like on a scale.
  • the video processor device is a device that converts an image signal generated by the CCD 17 into a video signal that can be displayed on a monitor. When connected to the connector force S connection, the video processor device and the CCD 17 are electrically connected. For this purpose, the image signal generated by the CCD 17 is input to the video processor device and converted into a signal that can be displayed on the monitor.
  • the light source processor device is designed such that when it is connected to the connector force S connection, the light from the optical butterfly is placed on the window provided in the connector.
  • the raw image can be displayed on the monitor by the electronic internal system.
  • FIG. 2 is a side view and an enormous cross-sectional view of one of the 11 vaginal cancer treatment catheters of the present invention.
  • the force tensioner of this aspect has an operating portion 8 at the near vertical end and a tip electrode 9 made of X-ray failure material 1 at the vertical end, and the operating rod 8 and the distal end rod 9 are at least one.
  • the shaft 10 is composed of a flexible distal portion 10a with a distal-law rule and a proxy mano 0b with a3 ⁇ 4-rigidity, which is a near-law rule.
  • ⁇ ⁇ ⁇ 0 b has a braid, that is, a net force s built in, a squeezing force s preferred, etc.
  • the Shore hardness measured according to JISZ 2246 is preferably 20 to 65 HSD, 30 It is more preferred to be 55 HSD
  • the material of the shelf that forms the Proxymano Vf 10b should have a shore hardness measured according to JISZ 2246 of 40-80 HSD S, preferably 55-75 HSD In this paper, the Shore hardness is measured using only the resin material, that is, the above Shore hardness is the resin material itself before incorporating the braid. The Shore hardness.
  • the flT cancer therapeutic power Tetenole of the present invention comprises a shaft 10; a flexible distorter on the heel side 3 ⁇ 4 1 0 a and a proxy mano 3 ⁇ 4 1 0 b with proximal 3 ⁇ 4S stiffness and a 3 ⁇ 4S stiffness
  • the shaft ⁇ (law can be bent freely, and the tip ®f3 ⁇ 4 9 can be turned into healing.
  • the shaft 10 is pushed into the bronchus and rolled, it becomes a flexible distano!
  • a lead wire 1 1 for transmitting high-frequency energy to the tip ®f ⁇ 9 and a sensor 1 2 disposed in the vicinity of the tip rod 9 are passed through the bow I.
  • Lead wire 1 The view of 1 and sensor 1 2 is drawn to the inside of the nearest operation 8. The far end of conductor 1 1 and the upright end of sensor 1 2 are soldered inside tip 9. It is fixed by 1 3.
  • “Men may be duplicated in the shaft 10, for example, 3 screws in the shaft 10! It is also possible to install a mandrel and pass the lead wire 1, sensor 1 2, and back operation wire separately in each notch.
  • examples of the X-ray non-material constituting the tip fistula include platinum, gold, platinum-iridium alloy having a high XH ⁇ property.
  • the position of the tip of the catheter can be easily identified by X 3 ⁇ 4M images, CT, etc. offshore.
  • Platinum, gold, platinum iridium alloys, etc. have good biocompatibility and high appreciation, so they can be said accurately.
  • a soft plastic or the like can be used as the resin material constituting the shaft 10, and examples of the soft plastic include polyurethane and nylon elastomer. it can.
  • examples of the material constituting the conductive wire 11 include copper, copper alloy, aluminum, platinum, and gold. These ⁇ S materials are electric Since the conductivity is high, high-frequency energy can be efficiently i3 ⁇ 4f even if the wire diameter is reduced to pass through the shaft 10.
  • a thermistor can be used as the sensor 12 used in the lung cancer treatment catheter of the present invention. If a thermal m3 ⁇ 4f thermistor meter is used as the sensor 12, the accuracy near the body temperature is high, and it can be made thin enough to pass through the shaft, so that it can be used as a monthly therapeutic catheter. This sensor 12 can perform 3 ⁇ 4T operation while measuring the thickness of the tip 9, so that it can be applied to.
  • Fig. 3 is a partial partial cross-sectional view of an impact showing a glimpse of the inverted state of the lung cancer treatment catheter of the present invention.
  • the light lit by the light guide 16 illuminates the affected area by irradiating the treatment eye through the light distribution lenses 5 and 6.
  • the image of the affected area is collected by the condenser lens 7, converted from an optical signal to an electrical signal by the CCD 17 and sent to the light source processor device via ⁇ 3H18 and reproduced as an image on the monitor. Is visually recognized.
  • the vaginal cancer treatment catheter of the present invention includes cooling: a fine fistula for cooling the tip electrode.
  • a thread ⁇ pipe 19 that needles from the near end to the distal end in the shaft and a drain pipe 20 force S at the proximal end are provided.
  • the tip temporary suspension 9 can be cooled by pouring water into the lung cancer treatment catheter from the thread fek tube 19 and draining water from the drain tube 20!].
  • a cooling water piping (For example, the thing using the water supply pipe 19 and the water pipe 20 etc.), a Peltier device, a heat pipe, etc. can be mentioned.
  • the cooling water pipe can be suitably used because the tip comfort 9 can be efficiently cooled by passing the thin steel pipe through the shaft.
  • the tip ⁇ 9 can be prevented from overheating and the desired cancer cells can be removed.
  • the cooling mechanism P is used only for a highly admirable attachment such as gold, anoremi, copper, copper alloy, etc., fixed to the tip comfort chamber 9, It ’s not possible to bypass the sensor.
  • Fig. 4 is an explanatory diagram of the treatment method using the catheter of the present invention.
  • the pipe that branches in the inner net image shows multiple holes at the branch point on the screen. Select and guide IKiiii ⁇ to the desired treatment.
  • the catheter 26 is inserted into the endoscope channel 14 and the inner! ⁇ Observe (visually) the image and place a storm stand with a force tensioner near the affected area.
  • the CT image monitor 27 it is determined whether the distal end (tip electrode 9) of the catheter made of the X-ray defect 1 substance is positioned in the vicinity of the targeted cancer cell. Since it is difficult to determine whether a cancer cell is normal or normal if it is only the inner neon image, it is preferable to always view it as a CT image.
  • the inner tube 24 is stopped before the position where the cancer cell is located, and the inner channel 14 The top end can be pushed further. In this ⁇ , guide the inner tip to the vicinity of the cancer cell while viewing the inner image, and then guide the tip 9 to the cancer cell while viewing the CT image.
  • the catheter according to the present invention since the flexibility of the Distano is increased, the diameter of the distal end of the endoscope 24 is thin, and the distal end of the catheter can be easily guided to the bronchial periphery. You can.
  • the physiology of 0 ⁇ 25 ° C-y usually 4 ° C of physiology 3 ⁇ 43 ⁇ 47] is sent as cooling water from the ⁇ _k pipe 19 of the force tenor shown in Fig. 2.
  • water is passed through the catheter. It is preferable to dispose of water completely as wastewater instead of circulation.
  • By completely throwing away (b) 7_) Even if the surface is scratched and the subject's ⁇ is ⁇ ! ⁇ inside the catheter, it can prevent secondary infection. It should be noted that the catheter used for heart examination, etc.
  • the test subject to 3 ⁇ 413 ⁇ 4 is equipped with anti-28, and the test conduction to tip comfort 9 and anti-healing 28 is performed with low ®E, resulting in impedance! ⁇ , Do. Impedance is too high ⁇ 1 If the tip m ⁇ 9 and the treatment site (tumor tissue) are considered to be transversal, (the tip comfort 9 is from the treatment sound), Again the treatment of tip consolation 9! 5 (Adjust the position of the One dance ability S Make it low enough. If the impedance is too high, the tissue cannot be heated sufficiently even when energized.
  • the lead wire 1 that transmits high frequency energy to the tip ⁇ 9 in the catheter shaft 1 ⁇ is connected to the generator 2 9 via the catheter operation section 8, and the counter 2 8 is also connected to the generator 29. ing.
  • the anti-needles can also be placed on the subject's back.
  • the cancer treatment catheter of the present invention can be provided with an operation wire (not shown) for bending the distal end.
  • the operation wire include stainless steel and NiTi alloy. Since these wires have high breakage, they can be threaded through shaft 10 with thin fibers. Using the operation wire, it is possible to remove the tip comforter 9 with high accuracy by using the internal bending and the bending of the force tail in two directions.
  • the catheter itself is bent by the operation wire and the operation rod 15 8 and the shaft 10 are rotated to move to the desired bronchus (branch) direction.
  • the catheter's ⁇ (right end can be pointed. If the catheter is pushed in as it is, the catheter will be inserted into the desired bronchus and force 5 will be inserted into the bronchus. You can lead tip consolation 9 to.
  • the catheter for treating lung cancer of the present invention has a shaft: force that m ⁇ is 2 ⁇ 0 mm or less S, preferably 1.7 mm or less.
  • Many bronchoscopes are ⁇ 6-7 mm, so if the catheter shaft bottle exceeds 2. O mm, it may be difficult to insert and operate the tracheostomy channel. is there.
  • Fig. 5 is a diagram showing the distribution in the body of the subject. The reason is the distance from the catheter tip 9 toward the inside of the paper weave, and the vertical axis is the separation in the S .
  • a high frequency is oscillated by the generator 29 in the state shown in FIG. 4, a high frequency m force S that spreads from the tip 9 to the f healing 28 is formed. Therefore, the dielectric constant of the tissue in the body Assuming that is constant, the distribution in the body is the distribution indicated by the dot of Fig. 5 that gradually decreases from tip comfort to 3 ⁇ 43 ⁇ 43 ⁇ 4. At this time, when cooling the tip comfort with the cooling leak side, as in the solid line of Fig. 5,
  • the distribution is uneven. In this way, by adjusting the strength of the high frequency and the strength of the cooling, it is possible to effectively cauterize cancer cells that control the peak and its position.
  • Fig. 6 is a graph showing the time course of the impedance of the tip dew 9 when heated using the catheter of the present invention, the consumption 3 ⁇ 4 ⁇ and the impedance between the tip 28 and the tip 9 It is an example.
  • the horizontal axis represents «time (t)
  • the vertical axis represents tip 9 and treatment (T)
  • consumption « ⁇ (W) or anti-professional 28 and tip comfort. Impedance between 9 and ( ⁇ ).
  • the high frequency current is worked out, the treatment gradually increases with time.
  • the high frequency correction is narrowed down and the 7th order water is rejected. Control the flow rate to keep the treatment at a certain constant value.
  • the consumption m3 ⁇ 4 (w) becomes a substantially constant value.
  • Impedance ( ⁇ ) between net 2 28 and tip comfort 9 gradually decreases as the caloric fever progresses, but when it burns too much and the tissue burns, it jumps up as shown by the dotted line in the figure . Therefore, impedance power S is preferable to stop energization shortly before jumping up or at the moment of sudden rise.
  • the age at which cancer is treated using the vaginal cancer treatment catheter of the present invention is cauterized by high-frequency energization of cancer cells using the monthly therapeutic power tenure of the present invention.
  • the distal heel of the cancer treatment catheter that does not damage the bronchi can reach the ridge region of the bronchus, and the tip comfort can be treated accurately
  • stable high-frequency output and SJ control allow the affected area to be removed without any risk of bleeding, and can accommodate large M3 ⁇ 4 through repeated cauterization.
  • the vaginal cancer treatment catheter of the present invention can be suitably applied not only to the ablation of B3 ⁇ 43 ⁇ 4H "in the bronchi but also to the ablation of 3 ⁇ 43 ⁇ 4 in the bronchus.
  • Nylon elastomer with a length of 1, 10 O mm, ⁇ 1.7 mm and 4 channels
  • a copper high-frequency conductor, ⁇ -type heat m3 ⁇ 4 "(chromel z alumel), stainless steel operation wire and O3 ⁇ 43 ⁇ 4 water pipe and drain pipe are inserted into the shaft, and the vertical end is 5 mm long made of platinum-lysium alloy. The tip was attached, and a maneuver was attached to the proximal end, and the needles of the lung cancer treatment catheter shown in FIG. 2 and FIG.
  • This lung cancer treatment catheter is connected to a high-frequency generator ⁇ , passed through a 6 mm tracheal 3 ⁇ 4 ⁇ working channel, inserted into the right bronchus of Hedge, and oscillated at a high frequency of 500 kHz for 30 seconds.
  • the tip & g was controlled at 90 ° C, and cauterization was performed without draining water. T Work marks, bleeding, and scorching were found in the comfort area.
  • the left middle lobe bronchus was cauterized in the same manner as in Example 1 except that the tip comfort was controlled at 60 ° C. There was a slight burning mark in the comfort area, and it was not bleed and scorching.
  • Example 2 Add cooling water to the cooling water piping to reduce the tip comfort.
  • the left upper lobe bronchus was crushed in the same manner as in Example 1 except that it was controlled at ° c. In the cautery, there was a burnt trace, and no bleeding or scorching was observed.
  • the right middle lobe bronchus was crushed in the same manner as in Example 1 except that cooling water was passed through the culvert pipe and the output of the high frequency female was 15 W. In the cautery part, 3 ⁇ 4t scar S was observed, and bleeding and scorching were not observed.
  • Table 2 shows the adhesive paste for the lung cancer treatment catheter of the present invention, which is ⁇ by m ⁇ to 5, and the treatment by the conventional sickle snare, laser, and RFA (radiofrequency ablation).
  • the snare used for excision of the tumor in the field cannot be applied except for the bleeding of the excision from the treatment wipe and the small size found on the shelf.
  • treatment to cauterize the bronchial moon crane by laser is also being tried, it is impossible to control the treatment request, which causes bleeding and scorching due to excessive calories.
  • the fiber that guides the laser cannot be moved, it is difficult to accurately irradiate the target beam.
  • RF A Radiopo Induction Therapy
  • a metal eddle is pierced and cauterized;
  • With a sensor at the needle tip and control, there is a risk of bleeding Because there is little and can be cauterized repeatedly, it is a force that can be expected to have a therapeutic effect even for large ulcers.Since the needle itself is hard and lacks flexibility, blood vessels ⁇ ; You can't use it.
  • the catheter of the present invention has a thin and flexible shaft, and can reach the moon crane in the shore region beyond the blood vessel branch.
  • a steerable arm is provided to accurately contact the vicinity of the treatment sound stand.
  • it is equipped with a sensor and a cooling ring, and with stable output and control, there is little risk of bleeding, and it is possible to cope with large tumors by repeated cauterization.
  • the distal end of the shaft is configured flexibly, and the f «of the shaft easily bends along the curve of the blood vessel or trachea. You can make the spider reach the tumor in the shout region. Furthermore, by providing an operation wire to bend ⁇ ⁇ ⁇ ⁇ ⁇ , the inside! 3 ⁇ 4 bending and catheter bending

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Abstract

L'invention concerne un cathéter pour le traitement d'un cancer du poumon caractérisé en ce qu'il comprend l'arbre (10) formé d'une partie distale (10a) flexible et d'une partie proximale (10b) disposée au plus près de l'extrémité proximale que la partie distale et ayant une rigidité supérieure à celle de la partie distale, l'arbre (10) ayant une lumière formée à travers la partie distale et la partie proximale ; l'électrode (9) ajustée à la partie distale de l'arbre ; la sonde de température (12) placée à proximité de l'électrode ; et le fil conducteur (11) tiré à l'intérieur de la lumière et ayant sa une extrémité connecté à l'électrode. De plus, une méthode de traitement d'un cancer du poumon est décrite qui utilise ledit cathéter. Le cathéter de traitement d'un cancer du poumon peut atteindre la périphérie des bronches, et peut être disposé dans un site de traitement sous observation en combinaison avec un endoscope, et peut cautériser des cellules de cancer du poumon en passant un courant de haute fréquence.
PCT/JP2007/057513 2006-03-28 2007-03-28 Cathéter de traitement pour un cancer du poumon et méthode de traitement d'un cancer du poumon WO2007111386A1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2006088228 2006-03-28
JP2006-088228 2006-03-28
JP2007-083410 2007-03-28
JP2007083410A JP2007289674A (ja) 2006-03-28 2007-03-28 肺癌治療カテーテル

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WO2007111386A1 true WO2007111386A1 (fr) 2007-10-04

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103800072A (zh) * 2012-11-09 2014-05-21 上海微创电生理医疗科技有限公司 端电极及其与电生理导管的装配方法

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090318943A1 (en) * 2008-06-19 2009-12-24 Tracee Eidenschink Vascular intervention catheters with pacing electrodes
US9037235B2 (en) 2008-06-19 2015-05-19 Cardiac Pacemakers, Inc. Pacing catheter with expandable distal end
JP2015057080A (ja) * 2012-01-12 2015-03-26 テルモ株式会社 体内組織焼灼システム
CN210811484U (zh) 2018-09-14 2020-06-23 杭州堃博生物科技有限公司 利于换热介质分配的射频消融导管

Citations (2)

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Publication number Priority date Publication date Assignee Title
JPH08308853A (ja) * 1995-05-22 1996-11-26 Atsuo Kitano カテーテルアブレーション式治療装置
JP2003534037A (ja) * 2000-03-17 2003-11-18 リタ メディカル システムズ インコーポレイテッド 肺処置装置

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08308853A (ja) * 1995-05-22 1996-11-26 Atsuo Kitano カテーテルアブレーション式治療装置
JP2003534037A (ja) * 2000-03-17 2003-11-18 リタ メディカル システムズ インコーポレイテッド 肺処置装置

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103800072A (zh) * 2012-11-09 2014-05-21 上海微创电生理医疗科技有限公司 端电极及其与电生理导管的装配方法

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