WO2007111386A1

WO2007111386A1 - Lung cancer treatment catheter and method of lung cancer treatment

Info

Publication number: WO2007111386A1
Application number: PCT/JP2007/057513
Authority: WO
Inventors: Kenji Tsushima; Tadatsugu Onuma
Original assignee: Shinshu University; Japan Lifeline Co., Ltd.
Priority date: 2006-03-28
Filing date: 2007-03-28
Publication date: 2007-10-04
Also published as: JP2007289674A

Abstract

A lung cancer treatment catheter characterized by including shaft (10) provided with flexible distal part (10a) and proximal part (10b) disposed nearer to the proximal end than the distal part and having rigidity higher than that of the distal part, the shaft (10) having a lumen formed through the distal part and proximal part; electrode (9) fitted to the distal part of the shaft; temperature sensor (12) disposed in the vicinity of the electrode; and conductor wire (11) drawn through the interior of the lumen and having its one end connected to the electrode. Further, there is provided a method of lung cancer treatment using this catheter. The lung cancer treatment catheter can reach the periphery of the bronchi, and can be disposed in a treatment site under observation in combination with an endoscope, and can cauterize the lung cancer cells by high-frequency current passage.

Description

Description Lung cancer treatment catheter and cancer treatment;

The present invention relates to a lung cancer treatment catheter. More specifically, the present invention relates to a lung cancer treatment catheter that can be delivered to the bronchus, placed in a jigsaw Pf under observation in combination with an internal fistula, and capable of cauterizing cancer cells by high-frequency energization. The present invention relates to a method for treating vaginal cancer. Background

Lung cancer occurs when cells in the trachea, bronchus, and alveoli lose their normal function and increase. Cancer grows by destroying the surrounding paper organs and spreads to other) βs, forming many moons. The number of people with flf cancer is increasing worldwide. The number of deaths from lung cancer in Japan in 1999 was about 52,000, but this is expected to increase in the future.

1 9 8 Monthly cancer screening has been introduced in each municipality Neo since «f. In 1 9 1 year, the number of lung cancer screenings exceeded 55 million, of which 2, 2 to 0 were diagnosed with lunar iff cancer. The proportion of lung cancer found at screening is less than 10% of the summary, but the vaginal cancer discovered at screening is earlier than the lung seats found with subjective symptoms such as hemorrhoids, hemorrhoids, and blood clots. There are many.

The lunar cancer screening is generally performed by chest x-ray suppression and sputum cytology, but: X-ray tomography of the lung called helical CT has become widespread, and smaller vaginal cancer has been discovered. Talk. Shelf Moon F (F cancer is an effective treatment method for cancer. For example, the 5-year survival rate of stage I month summary is said to be 70%. Let's go.

Conventionally, as an external method for cancer, the affected area of the lung: ^ 0 removal, moonctomy, unilateral lung removal, lymph node dissection, and so on. However, small moon cakes have been discovered, and it has become necessary to remove small parts of the lungs and perform cauterization. The excision with a snare used for excision in the extremity 1¾ field is applicable only to a moon crane with a lot of bleeding from the treatment ^: and the small size found. A trial of ablation of the bronchial moon crane with a laser has been tried, but because of the inability to control the treatment, bleeding caused by excessive caloric fever has occurred. Also, because the FINO-KUI that leads the laser cannot be powered, the targeted treatment 眘 | 5f

Radical skin with a proven track record in the treatment of liver cancer; ^ Acupuncture (RFA) is a treatment in which a needle is pierced into a crest and cauterized; ^: With the i¾ sensor at the tip of the needle, it can be controlled to control bleeding Since it can be repeated repeatedly with little risk, a therapeutic effect can be expected even for a large ffl¾. However, because the needle itself is hard and lacks flexibility, it cannot be used for long and wrinkled folds such as blood vessels. Disclosure of the invention

An object of the present invention is to provide a lung cancer treatment catheter that can reach the bronchial shrimp, and can be placed under treatment in combination with internal fibrils, and can treat cancer cells by high-frequency energization. Is.

As a result of intensive efforts to solve the above-mentioned concessions, the present inventors penetrated a catheter having a tip heel into the inner neck to reach the tumor in the bronchial region, and outside the patient's body. By inductively heating the affected area in the high-frequency electric field consisting of the installed anti-protrusion and the tip of the catheter, it is possible to safely and reliably produce monthly cells; The present invention has been made based on the findings.

That is, the present invention

(1) Flexible ["Distano with life! ^ And formed on the near side of the distanno l ^, Oka IJ is higher than the distal part, and has a proximal part. , Knitting distano 1 ^ 5 and iJlS proxy, ^

The lift on the shaft of the lift shaft itself,

With a sensor installed near me,

Lung cancer treatment catheter with one end connected to «ίίΙ5« ί 亟 and a lead wire led inside the ΙίίΒ men,

(2) In the selfish shaft, an operation wire for bending far is provided, and the moon fff cancer described in (1), therapeutic power Tetenole,

(3) The lung cancer treatment catheter according to (1) or (2), wherein the shaft outer diameter is 2.0 mm or less,

(4) The cooling mechanism that cools the f & f itself is further provided inside the tin shaft (1) to (3)! /, Lung cancer treatment catheter according to claim 1,

(5) The Shore hardness of Tatsumi Deistano 1 ^ ¾ is 2 0-6 5 HSD, The ffflB proximal part has a Shore hardness of 40 to 80 HSD (1) to (4) or a vaginal cancer treatment catheter according to item 1,

(6) The lung cancer treatment catheter according to any one of (1) to (5), wherein the tiff shaft is used by being inserted into the inner channel.

(7) The vaginal cancer treatment catheter according to (6), wherein the inner path of disgust is a bronchoscope, and

(8) It is formed on the proximal end side of the distal part having flexibility and the proximal part, and has a higher rigidity than the distano ι ^ and has a proximal part. Ίί || Prox ^^^ / Tomenka s formed with a shaft,

tin self shaft distano! ^ |

tfit me with a sensor near mse,

One end of it is connected to disgust, dislike 5 ^ "

A lung cancer treatment catheter equipped with a catheter is passed through an endoscope to reach the end of the bronchial region, and the affected part is induction heated by applying a high frequency m between the opposite side of the patient's body and Satoshi Tsutomu Treatment of acupuncture cancer with ablation of ablating cancer cells; ^

It is something to do. Brief Description of Drawings

Fig. 1 is an example of an endoscope used in combination with the monthly therapy catheter of the present invention. The # 1 view and the distal end of the endoscope are shown! ¾ view, Fig. 2 ίΐφ: Bfl¾) S, side view and schematic cross-sectional view of ¾ of therapeutic power, and Fig. Fig. 4, Fig. 4 is an explanatory view of the treatment using the vaginal cancer treatment catheter of the present invention, Fig. 5 shows the distribution in the body of the subject, Fig. 6 shows the distribution of the subject, Fig. 6 shows the catheter of the present invention FIG. 4 is an example of a graph showing ¾¾ of a previous case, heating Λ, and a change with time of impedance between a pair and a tip electrode when heated by using. In the figure, reference numeral 1 is an operation, 2 is an insertion port, 3 i¾t4 ^ operation dial, 4 is an opening, 5 and 6 are light distribution lenses, 7 is a condenser lens, 8 is an operation unit, 9 is a tip H 亟, 1 0 is shaft, 1 0 a is daistano V¾5, 1 0 b is proxy mano ^, 1 1 is lead, 1 2 is sensor, 1 3 is solder, 1 4 is channel, 1 6 is light guide, 1 7 is CCD, 1 8 is 酉 3 line, 1 9 is thread tube, 2 0 is drain pipe, 2 1 is subject, 2 2 is CT scanning device, 2 3 is bed, 2 4 is endoscope, 2 5 is internal Endoscopic image monitor, 26 is a catheter, 27 is a CT image monitor, 28 is a counter electrode, 29 is a generator (Best Mode for Carrying Out the Invention

The lunar therapeutic power Tetenole of the present invention is a force Tetenole that is thinned in combination with the inner part in the treatment of lunar cancer, with manipulation at the proximal end (pro X ima 1) and X-rays at itf¾ (dista 1). It has a tip 亟 composed of a non-conductive material, and 遍 and 近 are connected by a shaft with at least one channel, and the shaft position ¾ί rule flexible bend and the proximal end rule Oka I 胜The shaft is made up of the Oka I part, and the shaft has a lead wire that transmits high-frequency energy to the tip, and a fig sensor that uses a strict slogan and power manipulation, and cooling leaks inside the channel. The catheter is equipped with a high-frequency energization for tip comfort. Monthly summary of the present invention

Therapeutic power Tetenor can be used not only for the treatment of cancer, which is a malignant tumor of the lung, but also for the treatment of good life in Tsukiichi.

The vaginal cancer treatment catheter of the present invention can be used particularly in combination with the trachea. There is no particular limitation on the TO in combination with the lung cancer treatment catheter of the present invention, and examples thereof include a finer scope using glass finer, an electronic inner surface using CCD, and the like. Among these, inside the electronic! ^ Can be preferably used.

Fig. 1 is a # 4 view of an aspect of an electronic net shelved in combination with the monthly summary treatment catheter of the present invention and a portion of the distant view thereof. The electronic interior of the main body is provided with the operation β 1 and the insertion port 2 force s at the proximal end, and the remote operation dial 3 force s for operation. At the remote end, an aperture 4, two light distribution lenses 5, 6 and a condenser lens 7 are provided.

Electronic inside! The system consists of a combination of an electronic network, a light source processor device and a monitor. The electronic housing has a body insertion portion, a control lever 151, a connection cable, and a connector (not shown). At the distal end of the body cavity insertion portion, light distribution lenses 5 and 6, a condensing lens 7 and an opening 4 are provided. At the far end of the body cavity insertion portion, there are C CD 17 arranged opposite to the condenser lens 7, 酉 BHl 8 connected to the C CD 17, and light distribution lenses 5 and 6 with their tips at the ends. Opposed light guides 1 6 forces S are provided. In addition, channel 1 4 force S connected to opening 4 is formed. Furthermore, a curved tree (not shown) force S is formed. In operation, 揷 inlet 2 force S connected to channel 1 is formed. In addition, an upright operation dial 3 is provided for bending the distal portion of the body cavity insertion portion. The connection cable is connected to the surface opposite to the operation dial 3 of the remote control dial 5 [5 1]. Connection cable rules include connectors Force S is provided. The light guide 16 and wiring 18 are passed through the connection cable. The wiring 18 is connected to a terminal provided on the connector. In addition, the light guide 16 faces the window provided in the connector.

The original processor unit is composed of hard and video processor units. It is provided on the side of the crane that can be connected to the connector for electronic endoscopy. The apparatus is an apparatus that emits visible light, ultraviolet light, and the like on a scale. The video processor device is a device that converts an image signal generated by the CCD 17 into a video signal that can be displayed on a monitor. When connected to the connector force S connection, the video processor device and the CCD 17 are electrically connected. For this purpose, the image signal generated by the CCD 17 is input to the video processor device and converted into a signal that can be displayed on the monitor. In addition, the light source processor device is designed such that when it is connected to the connector force S connection, the light from the optical butterfly is placed on the window provided in the connector. Therefore, when light is emitted from the original processor unit, light is emitted through the light guide 16 to the finished product. The light that is reflected on the raw # and weave is collected on the CCD 17 by the condenser lens 7, and an image of the raw foliage is formed on the CCD 17. For this reason, the raw image can be displayed on the monitor by the electronic internal system.

FIG. 2 is a side view and an enormous cross-sectional view of one of the 11 vaginal cancer treatment catheters of the present invention. The force tensioner of this aspect has an operating portion 8 at the near vertical end and a tip electrode 9 made of X-ray failure material 1 at the vertical end, and the operating rod 8 and the distal end rod 9 are at least one. The shaft 10 is composed of a flexible distal portion 10a with a distal-law rule and a proxy mano 0b with a¾-rigidity, which is a near-law rule. Λ ^ Ι 0 b has a braid, that is, a net force s built in, a squeezing force s preferred, etc. By incorporating the braid, while having flexibility, pushability, torquey ¾¾raw, etc. Destor Λ ^ Ι 0 a and Proxy Mano 1 <¾10 b are the power of being continuously integrated ^ S is preferable. The Shore hardness measured according to JISZ 2246 is preferably 20 to 65 HSD, 30 It is more preferred to be 55 HSD The material of the shelf that forms the Proxymano Vf 10b should have a shore hardness measured according to JISZ 2246 of 40-80 HSD S, preferably 55-75 HSD In this paper, the Shore hardness is measured using only the resin material, that is, the above Shore hardness is the resin material itself before incorporating the braid. The Shore hardness.

The flT cancer therapeutic power Tetenole of the present invention comprises a shaft 10; a flexible distorter on the heel side ¾ 1 0 a and a proxy mano ¾ 1 0 b with proximal ¾S stiffness and a ¾S stiffness As a result, the shaft ^ (law can be bent freely, and the tip ®f¾ 9 can be turned into healing. In other words, when the shaft 10 is pushed into the bronchus and rolled, it becomes a flexible distano! ^ 1 0 a Force S Bends along the curve of the tracheal branch When the shaft 1 0 is further pushed in, the proximal part 1 0 b also bends along the curve of the bronchus following the distant portion 1 0 a In addition, since Distano 1 ^ ¾ 1 0 b has rigidity, it can easily push shaft 1 0. Therefore, treatment is bronchial (ie, one female branch from bronchus). Even after passing through a carp). Yore The ether and Ru, a HONORS 1 0 a since it is possible to push it along a curve of the bronchial can be 撤虫 tip ¾ 亟 9 to the treatment 咅啦.

Inside the sleeve of the shaft 10, a lead wire 1 1 for transmitting high-frequency energy to the tip ®f 亟 9 and a sensor 1 2 disposed in the vicinity of the tip rod 9 are passed through the bow I. Lead wire 1 The view of 1 and sensor 1 2 is drawn to the inside of the nearest operation 8. The far end of conductor 1 1 and the upright end of sensor 1 2 are soldered inside tip 9. It is fixed by 1 3. It should be noted that “Men may be duplicated in the shaft 10, for example, 3 screws in the shaft 10! It is also possible to install a mandrel and pass the lead wire 1, sensor 1 2, and back operation wire separately in each notch.

In the vaginal cancer treatment catheter of the present invention, examples of the X-ray non-material constituting the tip fistula include platinum, gold, platinum-iridium alloy having a high XH ^ property. By constructing the tip ¾ί 亟 with X ¾i material, the position of the tip of the catheter can be easily identified by X ¾M images, CT, etc. offshore. Platinum, gold, platinum iridium alloys, etc. have good biocompatibility and high appreciation, so they can be said accurately.

In the lupus treatment catheter of the present invention, a soft plastic or the like can be used as the resin material constituting the shaft 10, and examples of the soft plastic include polyurethane and nylon elastomer. it can.

In the moon treatment catheter of the present invention, examples of the material constituting the conductive wire 11 include copper, copper alloy, aluminum, platinum, and gold. These ^ S materials are electric Since the conductivity is high, high-frequency energy can be efficiently i¾f even if the wire diameter is reduced to pass through the shaft 10.

As the sensor 12 used in the lung cancer treatment catheter of the present invention, for example,

A thermistor can be used. If a thermal m¾f thermistor meter is used as the sensor 12, the accuracy near the body temperature is high, and it can be made thin enough to pass through the shaft, so that it can be used as a monthly therapeutic catheter. This sensor 12 can perform ¾T operation while measuring the thickness of the tip 9, so that it can be applied to.

Fig. 3 is a partial partial cross-sectional view of an impact showing a glimpse of the inverted state of the lung cancer treatment catheter of the present invention. In the main weaving, the light lit by the light guide 16 illuminates the affected area by irradiating the treatment eye through the light distribution lenses 5 and 6. The image of the affected area is collected by the condenser lens 7, converted from an optical signal to an electrical signal by the CCD 17 and sent to the light source processor device via 酉 3H18 and reproduced as an image on the monitor. Is visually recognized.

The vaginal cancer treatment catheter of the present invention includes cooling: a fine fistula for cooling the tip electrode. In H shown in FIG. 2, a thread ΒτΚ pipe 19 that needles from the near end to the distal end in the shaft and a drain pipe 20 force S at the proximal end are provided. The tip temporary suspension 9 can be cooled by pouring water into the lung cancer treatment catheter from the thread fek tube 19 and draining water from the drain tube 20!]. In addition, there is no restriction | limiting in particular in the cooling tree to be used, For example, a cooling water piping (For example, the thing using the water supply pipe 19 and the water pipe 20 etc.), a Peltier device, a heat pipe, etc. can be mentioned. Among these, the cooling water pipe can be suitably used because the tip comfort 9 can be efficiently cooled by passing the thin steel pipe through the shaft. By providing a cooling tree and cooling the tip 冓 9, even if a large amount of high-frequency energy is output, the tip 出力 9 can be prevented from overheating and the desired cancer cells can be removed. . In the moon cancer treatment catheter according to the present invention, the cooling mechanism P is used only for a highly admirable attachment such as gold, anoremi, copper, copper alloy, etc., fixed to the tip comfort chamber 9, It ’s not possible to bypass the sensor.

Fig. 4 is an explanatory diagram of the treatment method using the catheter of the present invention. Lay the Neighbor 2 1 on the CT Scanning Device 2 2 Force S Bed 2 3 installed. Insert the ^ 2 of the electronic inside 2 4 through the subject's nose or mouth, guide the key end to the bronchi while viewing the inner ¾ image monitor 2 5, and «I end in front of the cancer cell To stop. Note that the pipe that branches in the inner net image shows multiple holes at the branch point on the screen. Select and guide IKiiii 耑 to the desired treatment.

Next, as shown in Fig. 3, the catheter 26 is inserted into the endoscope channel 14 and the inner! ^ Observe (visually) the image and place a storm stand with a force tensioner near the affected area. At this time, while looking at the CT image monitor 27, it is determined whether the distal end (tip electrode 9) of the catheter made of the X-ray defect 1 substance is positioned in the vicinity of the targeted cancer cell. Since it is difficult to determine whether a cancer cell is normal or normal if it is only the inner neon image, it is preferable to always view it as a CT image.

In addition, at the age of cancer cells with a trachea that is narrower than the tip of the inner tube 24, the inner tube 24 is stopped before the position where the cancer cell is located, and the inner channel 14 The top end can be pushed further. In this ^^, guide the inner tip to the vicinity of the cancer cell while viewing the inner image, and then guide the tip 9 to the cancer cell while viewing the CT image. As shown in ¾6, according to the catheter according to the present invention, since the flexibility of the Distano is increased, the diameter of the distal end of the endoscope 24 is thin, and the distal end of the catheter can be easily guided to the bronchial periphery. You can.

Next, the physiology of 0 ~ 25 ° C-y usually 4 ° C of physiology ¾¾7] is sent as cooling water from the ^ _k pipe 19 of the force tenor shown in Fig. 2. By draining water, water is passed through the catheter. It is preferable to dispose of water completely as wastewater instead of circulation. By completely throwing away (b) 7_) Even if the surface is scratched and the subject's ί is ί! Λ inside the catheter, it can prevent secondary infection. It should be noted that the catheter used for heart examination, etc. is | 3 by the blood flow in the blood vessel, so there is little risk of overheating, but in the trachea where the lung cancer treatment catheter of the present invention is used Circulation 1 ~ Ru (e.g., blood) is very hot, so there is no cooling leakage, and if a catheter (e.g., a heart catheter) is used, the tip is extremely heated. There is a fear. On the other hand, this male and female can prevent overheating by cooling the catheter with cooling water (cooling) when performing 纖纖, so that it can be applied to the body.

In addition, the test subject to ¾1¾ is equipped with anti-28, and the test conduction to tip comfort 9 and anti-healing 28 is performed with low ®E, resulting in impedance! ^, Do. Impedance is too high ^ 1 If the tip m 翻 9 and the treatment site (tumor tissue) are considered to be transversal, (the tip comfort 9 is from the treatment sound), Again the treatment of tip consolation 9! 5 (Adjust the position of the One dance ability S Make it low enough. If the impedance is too high, the tissue cannot be heated sufficiently even when energized. The lead wire 1 that transmits high frequency energy to the tip 亟 9 in the catheter shaft 1◦ is connected to the generator 2 9 via the catheter operation section 8, and the counter 2 8 is also connected to the generator 29. ing. The anti-needles can also be placed on the subject's back.

When the subject is wearing a pair of electrodes 28, energization is started, and the impedance of the generator 2.9, ji, and impedance from the generator 29 connected to the catheter is reduced below the predetermined value. End energization. As the tissue is heated, the impedance tends to decrease. However, if the tissue is burnt due to over-baking, the impedance jumps to “^. Therefore, it is preferable to stop energization shortly before the impedance force s jumps up, or at the moment of rising.

The cancer treatment catheter of the present invention can be provided with an operation wire (not shown) for bending the distal end. Examples of the operation wire include stainless steel and NiTi alloy. Since these wires have high breakage, they can be threaded through shaft 10 with thin fibers. Using the operation wire, it is possible to remove the tip comforter 9 with high accuracy by using the internal bending and the bending of the force tail in _two directions. In order to insert the catheter tip to the branch bronchus * r, the catheter itself is bent by the operation wire and the operation rod 15 8 and the shaft 10 are rotated to move to the desired bronchus (branch) direction. The catheter's ^ (right end can be pointed. If the catheter is pushed in as it is, the catheter will be inserted into the desired bronchus and force 5 will be inserted into the bronchus. You can lead tip consolation 9 to.

The catheter for treating lung cancer of the present invention has a shaft: force that m 圣 is 2 · 0 mm or less S, preferably 1.7 mm or less. Many bronchoscopes are 圣 6-7 mm, so if the catheter shaft bottle exceeds 2. O mm, it may be difficult to insert and operate the tracheostomy channel. is there.

Fig. 5 is a diagram showing the distribution in the body of the subject. The reason is the distance from the catheter tip 9 toward the inside of the paper weave, and the vertical axis is the separation in the S . When a high frequency is oscillated by the generator 29 in the state shown in FIG. 4, a high frequency m force S that spreads from the tip 9 to the f healing 28 is formed. Therefore, the dielectric constant of the tissue in the body Assuming that is constant, the distribution in the body is the distribution indicated by the dot of Fig. 5 that gradually decreases from tip comfort to ¾¾¾. At this time, when cooling the tip comfort with the cooling leak side, as in the solid line of Fig. 5,

The distribution is uneven. In this way, by adjusting the strength of the high frequency and the strength of the cooling, it is possible to effectively cauterize cancer cells that control the peak and its position.

Fig. 6 is a graph showing the time course of the impedance of the tip dew 9 when heated using the catheter of the present invention, the consumption ¾Λ and the impedance between the tip 28 and the tip 9 It is an example. In this figure, the horizontal axis represents «time (t), and the vertical axis represents tip 9 and treatment (T), consumption« Λ (W) or anti-professional 28 and tip comfort. Impedance between 9 and (Ω). When the high frequency current is worked out, the treatment gradually increases with time. When it is estimated that the treatment dose has reached the prescribed value, the high frequency correction is narrowed down and the 7th order water is rejected. Control the flow rate to keep the treatment at a certain constant value. After the therapeutic value reaches a predetermined value and the high frequency m¾¾ value is narrowed down, the consumption m¾ (w) becomes a substantially constant value. Impedance (Ω) between net 2 28 and tip comfort 9 gradually decreases as the caloric fever progresses, but when it burns too much and the tissue burns, it jumps up as shown by the dotted line in the figure . Therefore, impedance power S is preferable to stop energization shortly before jumping up or at the moment of sudden rise. The age at which cancer is treated using the vaginal cancer treatment catheter of the present invention is cauterized by high-frequency energization of cancer cells using the monthly therapeutic power tenure of the present invention. If the lung cancer treatment catheter of the present invention is used, the distal heel of the cancer treatment catheter that does not damage the bronchi can reach the ridge region of the bronchus, and the tip comfort can be treated accurately | 5 (Nearly ^^^ In addition, stable high-frequency output and SJ control allow the affected area to be removed without any risk of bleeding, and can accommodate large M¾ through repeated cauterization. The vaginal cancer treatment catheter of the present invention can be suitably applied not only to the ablation of B¾¾H "in the bronchi but also to the ablation of ¾¾ in the bronchus.

Hereinafter, the present invention will be described in more detail with reference to examples. However, the present invention is not limited to these examples.

Bell train 1

Nylon elastomer with a length of 1, 10 O mm, 舰 1.7 mm and 4 channels A copper high-frequency conductor, κ-type heat m¾ "(chromel z alumel), stainless steel operation wire and O¾¾ water pipe and drain pipe are inserted into the shaft, and the vertical end is 5 mm long made of platinum-lysium alloy. The tip was attached, and a maneuver was attached to the proximal end, and the needles of the lung cancer treatment catheter shown in FIG. 2 and FIG.

This lung cancer treatment catheter is connected to a high-frequency generator β, passed through a 6 mm tracheal ¾ ^ working channel, inserted into the right bronchus of Hedge, and oscillated at a high frequency of 500 kHz for 30 seconds. The tip & g was controlled at 90 ° C, and cauterization was performed without draining water. T Work marks, bleeding, and scorching were found in the comfort area.

Difficult example 2

The left middle lobe bronchus was cauterized in the same manner as in Example 1 except that the tip comfort was controlled at 60 ° C. There was a slight burning mark in the comfort area, and it was not bleed and scorching.

Example 3

Add cooling water to the cooling water piping to reduce the tip comfort. The left upper lobe bronchus was crushed in the same manner as in Example 1 except that it was controlled at ° c. In the cautery, there was a burnt trace, and no bleeding or scorching was observed.

Difficult example 4

| 3 for water piping? ^ (1) The right lower lobe bronchus was cauterized in the same manner as in Example 1 except that 1 water was passed and the high frequency β output was 30 W. Scar marks were observed in the buttocks. Bleeding and scorching were not observed.

Example 5

The right middle lobe bronchus was crushed in the same manner as in Example 1 except that cooling water was passed through the culvert pipe and the output of the high frequency female was 15 W. In the cautery part, ¾t scar S was observed, and bleeding and scorching were not observed.

The results of Examples 1-5 are shown in Table 1. 1

As seen in Table 1, cauterization by high-frequency energization in the bronchi is possible for + ^. In particular, when tip consolation is used, high frequency can be output stably, and a positive chain effect can be obtained without causing bleeding and scorching.

Table 2 shows the adhesive paste for the lung cancer treatment catheter of the present invention, which is β by m ι to 5, and the treatment by the conventional sickle snare, laser, and RFA (radiofrequency ablation).

[Note] ○: Good, Δ :: Bad

The snare used for excision of the tumor in the field cannot be applied except for the bleeding of the excision from the treatment wipe and the small size found on the shelf. Although treatment to cauterize the bronchial moon crane by laser is also being tried, it is impossible to control the treatment request, which causes bleeding and scorching due to excessive calories. In addition, since the fiber that guides the laser cannot be moved, it is difficult to accurately irradiate the target beam.

Responsible for treating liver cancer, RF A (Radiopo Induction Therapy) is a treatment in which a metal eddle is pierced and cauterized; ^ With a sensor at the needle tip and control, there is a risk of bleeding Because there is little and can be cauterized repeatedly, it is a force that can be expected to have a therapeutic effect even for large ulcers.Since the needle itself is hard and lacks flexibility, blood vessels ^; You can't use it.

On the other hand, the catheter of the present invention has a thin and flexible shaft, and can reach the moon crane in the shore region beyond the blood vessel branch. In addition, a steerable arm is provided to accurately contact the vicinity of the treatment sound stand. In addition, it is equipped with a sensor and a cooling ring, and with stable output and control, there is little risk of bleeding, and it is possible to cope with large tumors by repeated cauterization. Industrial applicability

In the lung cancer treatment catheter of the present invention, the distal end of the shaft is configured flexibly, and the f «of the shaft easily bends along the curve of the blood vessel or trachea. You can make the spider reach the tumor in the shout region. Furthermore, by providing an operation wire to bend 窗設ける ^, the inside! ¾ bending and catheter bending

'You can remove insects in the vicinity of the treatment sound with high accuracy using the fold. Also, equipped with a sensor and a cool link, stable output and ^ g control, there is little risk of bleeding, and the affected area can be cauterized. Repeated cauterization can handle large moon cranes. It comes out.

Claims

The scope of the claims

1. Permanent I "Distal part with life, and the Distano! ^ Harimo Kyoji] is formed according to the 則 ¾ί rule, Oka (higher J characteristics, Proxyma Λ ^, A shaft that has been developed and opened in the self-disaster Λ ^ and fijf self-proxy mano V¾,

The comfort provided on the distal part of the shaft,

a sensor provided near tftlB¾¾fi,

• One end is connected to

The moon fj? Cancer treatment power Tetenore with glue. .

2. The table-top treatment catheter according to claim 1, further comprising an operation wire for bending the stand in the shaft. .

3. The moon width treatment catheter according to claim 1 or claim 2, wherein the shaft 圣 is 2.0 mm or less.

4. The lung cancer treatment catheter according to any one of claims 1 to 3, further comprising a cooling mechanism that cools the it itself within the tiff shaft.

5. The shore hardness of the self-stall is 20 ~ 6 5 H SD

The lung cancer treatment catheter according to claim 1, wherein the Shore hardness of the self-proximator is 40 to 8 OHSD.

6. The catheter for treating hemorrhoid cancer according to claim 1, wherein the shaft is inserted into the inner channel and used.

7. The lung cancer treatment catheter according to claim 6, wherein ttjf is a bronchoscope.

8. Dedicated I "Distor with life / | 5, and more distant than the Dista, the Distano! ^ Harimooka I 胜 has a high level, Proxyma, Distant Λ¾ and tirt self proxyma

ftlt comfort provided in the distal part of the shaft

tin me with a sensor near miifi,

One end of the knitting rod is connected to the tiilB / "

A pair of vaginal cancer treatment catheters equipped with an internal penetrator to reach the bronchial region and placed outside the patient's body; A method for treating lung cancer, which is based on cauterizing cancer cells by induction heating.