WO2006131231A1 - Azolopyridin-2-on-derivate als inhibitoren von lipasen und phospholipasen - Google Patents
Azolopyridin-2-on-derivate als inhibitoren von lipasen und phospholipasen Download PDFInfo
- Publication number
- WO2006131231A1 WO2006131231A1 PCT/EP2006/005095 EP2006005095W WO2006131231A1 WO 2006131231 A1 WO2006131231 A1 WO 2006131231A1 EP 2006005095 W EP2006005095 W EP 2006005095W WO 2006131231 A1 WO2006131231 A1 WO 2006131231A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- formula
- alkyl
- compounds
- alkylene
- hydrogen
- Prior art date
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/424—Oxazoles condensed with heterocyclic ring systems, e.g. clavulanic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Abstract
Description
Claims
Priority Applications (19)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
MX2007015347A MX2007015347A (es) | 2005-06-09 | 2006-05-27 | Derivados de azolopiridin -2- ona como inhibidores de lipasas y fosfolipasas. |
SI200630748T SI1896485T1 (sl) | 2005-06-09 | 2006-05-27 | Derivati azolopiridin ona kot inhibitorji lipazin fosfolipaz |
DK06753937.9T DK1896485T3 (da) | 2005-06-09 | 2006-05-27 | Azolopyridin-2-on-derivater som inhibitorer af lipaser og phospholipaser |
EP06753937A EP1896485B1 (de) | 2005-06-09 | 2006-05-27 | Azolopyridin-2-on-derivate als inhibitoren von lipasen und phospholipasen |
JP2008515095A JP2008542410A (ja) | 2005-06-09 | 2006-05-27 | リパーゼ及びホスホリパーゼ阻害剤としてのアゾロピリジン−2−オン誘導体 |
RSP-2010/0270A RS51268B (sr) | 2005-06-09 | 2006-05-27 | Derivati azolopiridina-2-on-a kao inhibitori lipaza i fosfolipaza |
AU2006257022A AU2006257022A1 (en) | 2005-06-09 | 2006-05-27 | Azolopyridine-2-on derivatives as lipase and phospholipase inhibitors |
BRPI0611688-4A BRPI0611688A2 (pt) | 2005-06-09 | 2006-05-27 | derivados azolopiridina-2-ona como inibidores de lipase e fosfolipase |
CA002610325A CA2610325A1 (en) | 2005-06-09 | 2006-05-27 | Azolopyridine-2-on derivatives as lipase and phospholipase inhibitors |
NZ564063A NZ564063A (en) | 2005-06-09 | 2006-05-27 | Azolopyridine-2-one derivatives as lipase and phospholipase inhibitors |
PL06753937T PL1896485T3 (pl) | 2005-06-09 | 2006-05-27 | Pochodne azolopirydyn-2-onu jako inhibitory lipaz i fosfolipaz |
DE502006006986T DE502006006986D1 (de) | 2005-06-09 | 2006-05-27 | Azolopyridin-2-on-derivate als inhibitoren von lipasen und phospholipasen |
AT06753937T ATE468342T1 (de) | 2005-06-09 | 2006-05-27 | Azolopyridin-2-on-derivate als inhibitoren von lipasen und phospholipasen |
IL187730A IL187730A0 (en) | 2005-06-09 | 2007-11-28 | Azolopyridine-2-on derivatives as lipase and phospholipase inhibitors |
US11/950,932 US7846943B2 (en) | 2005-06-09 | 2007-12-05 | Azolopyridin-2-one derivatives as lipase and phospholipase inhibitors |
NO20080133A NO20080133L (no) | 2005-06-09 | 2008-01-08 | Azolopyridin-2-on derivater som lipase og fosfolipaseinhibitorer |
CY20101100675T CY1110213T1 (el) | 2005-06-09 | 2010-07-20 | Παραγωγα αζολοπυριδιν-2-ονης ως αναστολεις λιπασων και φωσφολιπασων |
HR20100409T HRP20100409T1 (hr) | 2005-06-09 | 2010-07-23 | Derivati azolopiridin-2-ona kao inhibitori fosfolipaze |
US12/914,045 US20110039883A1 (en) | 2005-06-09 | 2010-10-28 | Azolopyridin-2-one derivatives as lipase and phospholipase inhibitors |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102005026762.9 | 2005-06-09 | ||
DE102005026762A DE102005026762A1 (de) | 2005-06-09 | 2005-06-09 | Azolopyridin-2-on-derivate als Inhibitoren von Lipasen und Phospholipasen |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US11/950,932 Continuation US7846943B2 (en) | 2005-06-09 | 2007-12-05 | Azolopyridin-2-one derivatives as lipase and phospholipase inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2006131231A1 true WO2006131231A1 (de) | 2006-12-14 |
Family
ID=37076291
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2006/005095 WO2006131231A1 (de) | 2005-06-09 | 2006-05-27 | Azolopyridin-2-on-derivate als inhibitoren von lipasen und phospholipasen |
Country Status (30)
Country | Link |
---|---|
US (2) | US7846943B2 (de) |
EP (1) | EP1896485B1 (de) |
JP (1) | JP2008542410A (de) |
KR (1) | KR20080019215A (de) |
CN (1) | CN101193896A (de) |
AR (1) | AR054132A1 (de) |
AT (1) | ATE468342T1 (de) |
AU (1) | AU2006257022A1 (de) |
BR (1) | BRPI0611688A2 (de) |
CA (1) | CA2610325A1 (de) |
CY (1) | CY1110213T1 (de) |
DE (2) | DE102005026762A1 (de) |
DK (1) | DK1896485T3 (de) |
ES (1) | ES2346561T3 (de) |
HR (1) | HRP20100409T1 (de) |
IL (1) | IL187730A0 (de) |
MA (1) | MA29481B1 (de) |
MX (1) | MX2007015347A (de) |
MY (1) | MY142792A (de) |
NO (1) | NO20080133L (de) |
NZ (1) | NZ564063A (de) |
PL (1) | PL1896485T3 (de) |
PT (1) | PT1896485E (de) |
RS (1) | RS51268B (de) |
RU (1) | RU2414473C2 (de) |
SI (1) | SI1896485T1 (de) |
TW (1) | TW200716653A (de) |
UY (1) | UY29593A1 (de) |
WO (1) | WO2006131231A1 (de) |
ZA (1) | ZA200709501B (de) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007110215A1 (en) * | 2006-03-28 | 2007-10-04 | Sanofi-Aventis | Imidazopyridin-2-one derivatives as inhibitors of endothelial lipase |
WO2009021740A2 (de) | 2007-08-15 | 2009-02-19 | Sanofis-Aventis | Substituierte tetrahydronaphthaline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
WO2010003624A2 (en) | 2008-07-09 | 2010-01-14 | Sanofi-Aventis | Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof |
WO2011157827A1 (de) | 2010-06-18 | 2011-12-22 | Sanofi | Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen |
US8754113B2 (en) | 2009-12-15 | 2014-06-17 | Shionogi & Co., Ltd. | Oxadiazole derivative having endothelial lipase inhibitory activity |
US8957219B2 (en) | 2008-10-17 | 2015-02-17 | Shionogi & Co., Ltd. | Acetic acid amide derivative having inhibitory activity on endothelial lipase |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9556201B2 (en) * | 2009-10-29 | 2017-01-31 | Glaxosmithkline Llc | Bicyclic pyridines and analogs as sirtuin modulators |
CN114560873B (zh) * | 2021-12-27 | 2023-02-28 | 浙江日出药业有限公司 | 一种3-氯甲基-6-氯-噁唑[4,5-b]吡啶-2(3H)酮的制备方法 |
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DE3835576A1 (de) * | 1988-03-25 | 1989-10-12 | Bayer Ag | 3,7-disubstituierte benzthiazolone |
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2005
- 2005-06-09 DE DE102005026762A patent/DE102005026762A1/de not_active Withdrawn
-
2006
- 2006-05-27 PT PT06753937T patent/PT1896485E/pt unknown
- 2006-05-27 DK DK06753937.9T patent/DK1896485T3/da active
- 2006-05-27 RS RSP-2010/0270A patent/RS51268B/sr unknown
- 2006-05-27 SI SI200630748T patent/SI1896485T1/sl unknown
- 2006-05-27 RU RU2007145499/04A patent/RU2414473C2/ru not_active IP Right Cessation
- 2006-05-27 CN CNA2006800202416A patent/CN101193896A/zh active Pending
- 2006-05-27 WO PCT/EP2006/005095 patent/WO2006131231A1/de active Application Filing
- 2006-05-27 EP EP06753937A patent/EP1896485B1/de active Active
- 2006-05-27 CA CA002610325A patent/CA2610325A1/en not_active Abandoned
- 2006-05-27 PL PL06753937T patent/PL1896485T3/pl unknown
- 2006-05-27 NZ NZ564063A patent/NZ564063A/en not_active IP Right Cessation
- 2006-05-27 ES ES06753937T patent/ES2346561T3/es active Active
- 2006-05-27 AU AU2006257022A patent/AU2006257022A1/en not_active Abandoned
- 2006-05-27 JP JP2008515095A patent/JP2008542410A/ja not_active Abandoned
- 2006-05-27 AT AT06753937T patent/ATE468342T1/de active
- 2006-05-27 KR KR1020077028710A patent/KR20080019215A/ko not_active Application Discontinuation
- 2006-05-27 BR BRPI0611688-4A patent/BRPI0611688A2/pt not_active IP Right Cessation
- 2006-05-27 DE DE502006006986T patent/DE502006006986D1/de active Active
- 2006-05-27 MX MX2007015347A patent/MX2007015347A/es active IP Right Grant
- 2006-06-07 TW TW095120135A patent/TW200716653A/zh unknown
- 2006-06-07 AR ARP060102373A patent/AR054132A1/es not_active Application Discontinuation
- 2006-06-07 MY MYPI20062625A patent/MY142792A/en unknown
- 2006-06-09 UY UY29593A patent/UY29593A1/es not_active Application Discontinuation
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2007
- 2007-11-05 ZA ZA200700950A patent/ZA200709501B/xx unknown
- 2007-11-22 MA MA30415A patent/MA29481B1/fr unknown
- 2007-11-28 IL IL187730A patent/IL187730A0/en unknown
- 2007-12-05 US US11/950,932 patent/US7846943B2/en not_active Expired - Fee Related
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2008
- 2008-01-08 NO NO20080133A patent/NO20080133L/no not_active Application Discontinuation
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2010
- 2010-07-20 CY CY20101100675T patent/CY1110213T1/el unknown
- 2010-07-23 HR HR20100409T patent/HRP20100409T1/hr unknown
- 2010-10-28 US US12/914,045 patent/US20110039883A1/en not_active Abandoned
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