WO2006038255A1 - 観察装置及びステージユニット - Google Patents
観察装置及びステージユニット Download PDFInfo
- Publication number
- WO2006038255A1 WO2006038255A1 PCT/JP2004/014339 JP2004014339W WO2006038255A1 WO 2006038255 A1 WO2006038255 A1 WO 2006038255A1 JP 2004014339 W JP2004014339 W JP 2004014339W WO 2006038255 A1 WO2006038255 A1 WO 2006038255A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- stage member
- observation
- stage
- main body
- holder
- Prior art date
Links
- 238000012806 monitoring device Methods 0.000 title abstract 2
- 239000000463 material Substances 0.000 claims description 20
- 230000008602 contraction Effects 0.000 claims description 8
- 238000010438 heat treatment Methods 0.000 claims description 5
- 230000002093 peripheral effect Effects 0.000 claims description 4
- 230000000149 penetrating effect Effects 0.000 claims 1
- 238000012544 monitoring process Methods 0.000 abstract 2
- 239000011521 glass Substances 0.000 description 6
- 230000007935 neutral effect Effects 0.000 description 5
- 238000000034 method Methods 0.000 description 4
- 239000004033 plastic Substances 0.000 description 4
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 2
- 229910052782 aluminium Inorganic materials 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 239000003153 chemical reaction reagent Substances 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- 239000013307 optical fiber Substances 0.000 description 2
- 230000002265 prevention Effects 0.000 description 2
- 239000011347 resin Substances 0.000 description 2
- 229920005989 resin Polymers 0.000 description 2
- 239000004065 semiconductor Substances 0.000 description 2
- 239000004696 Poly ether ether ketone Substances 0.000 description 1
- JUPQTSLXMOCDHR-UHFFFAOYSA-N benzene-1,4-diol;bis(4-fluorophenyl)methanone Chemical compound OC1=CC=C(O)C=C1.C1=CC(F)=CC=C1C(=O)C1=CC=C(F)C=C1 JUPQTSLXMOCDHR-UHFFFAOYSA-N 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 210000005260 human cell Anatomy 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 229920002530 polyetherether ketone Polymers 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 239000010453 quartz Substances 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N silicon dioxide Inorganic materials O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/24—Base structure
- G02B21/30—Base structure with heating device
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B7/00—Mountings, adjusting means, or light-tight connections, for optical elements
- G02B7/008—Mountings, adjusting means, or light-tight connections, for optical elements with means for compensating for changes in temperature or for controlling the temperature; thermal stabilisation
Definitions
- the present invention relates to an observation apparatus used as a microscope, a scientific instrument, a medical instrument, or the like.
- an observation object is placed on a stage, and focusing is performed by adjusting the relative positional relationship between the objective lens and the stage. Observations are made.
- a human cell or the like is used as an observation object, it is desirable to observe the observation object while maintaining the observation object at a temperature close to the human body (about 37 degrees Celsius).
- the observation apparatus reaches the predetermined temperature in a constant temperature controlled temperature controlled room for a certain period of time, or the entire observation apparatus is used.
- the object to be observed is heated to a predetermined temperature after being covered with a constant temperature hood.
- Japanese Patent Laid-Open No. 200-200707 Japanese Laid-Open Patent Publication No. 3-43373 proposes a technique for constructing an observation apparatus with a material having a low coefficient of thermal expansion.
- Japanese Patent Application Laid-Open No. 2002-207175 proposes that the observation apparatus is composed of a plurality of types of members having different coefficients of thermal expansion. However, in either case, there is a problem that the cost of the material is increased or the processing is not easy.
- An object of the present invention is to prevent defocusing relatively easily.
- the stage unit includes the first stage member on which the observation target is set and the first stage member. And a second stage member that supports the first stage member, the observation surface of the observation object set on the first stage member, and the placement unit An observation device is provided in which the contact surface between the first stage member and the second stage member is set on substantially the same horizontal plane.
- the first stage member on which the observation object is set and the placement portion on which the first stage member is placed are supported to support the first stage member.
- the observation surface of the observation object set on the first stage member is substantially the same as the contact surface between the first stage member and the second stage member in the mounting portion.
- the observation surface is positioned on the neutral plane of thermal strain of the first stage member. Therefore, the position of the observation surface does not change even if the first stage member is subjected to thermal strain. With this principle, it is possible to prevent focus deviation relatively easily.
- FIG. 1 is a cross-sectional view showing the structure of an observation apparatus A according to a first embodiment of the present invention.
- FIG. 2 is a partially enlarged view of the observation apparatus A in FIG. 1, and the positional relationship between the observation surface Z ′ and the upper surface of the mounting portion 32b (the contact surface between the first stage member 31 and the second stage member 32).
- FIG. 3 is an external view of an observation apparatus B according to a second embodiment of the present invention.
- FIG. 4 is a plan view of the observation apparatus B with the holder 1312 removed.
- FIG. 5 is a plan view of the observation apparatus B with the first stage member 131 removed.
- FIG. 6 is a cross-sectional view of stage unit 103 along line XI—XI in FIG.
- FIG. 7 is a cross-sectional view of the stage unit 103 taken along line X2-X2 in FIG.
- FIG. 8 A cross-sectional view of the main body portion 1311 along the line X3—X3 of FIG. 4, showing the configuration of the groove portion 131 lc.
- FIG. 9 is a cross-sectional view showing a main part of the structure of the observation apparatus B, and is a cross-sectional view showing a main part along the same line as X 2 -X 2 in FIG.
- FIG. 1 is a cross-sectional view showing the structure of an observation apparatus A according to the first embodiment of the present invention.
- This observation apparatus A includes a housing 1 that is open at the top, an objective lens 2 that is housed inside the housing 1, and a stage unit 3 that is mounted on the top surface of the housing 1.
- the stage unit 3 includes a first stage member 31 and a second stage member 32.
- the second stage member 32 is composed of a plate-like member having an opening 32a at the center thereof, and a mounting portion 32b on which the first stage member 31 is mounted around the opening 32a. Is formed.
- the first stage member 31 is mounted on the upper surface of the mounting portion 32b and the peripheral force of the bottom surface thereof is supported horizontally by the second stage member 32. That is, the upper surface of the mounting portion 32 b is a contact surface between the first stage member 31 and the second stage member 32.
- the first stage member 31 also includes a plate-shaped member having a recess 31a at the center thereof.
- An opening 31b is provided at the center of the recess 31a, and the bottom surface of the first stage member 31 is opened by the opening 31b.
- the observation object X is placed on the placement member Z and set on the bottom surface of the recess 31a from above the recess 31a in a state where the protection plate Y is placed thereon. At this time, the observation object X is set so as to be positioned above the opening 31b.
- the mounting member Z is a transparent or translucent member, and is composed of, for example, a plastic plate or glass plate force that hardly causes thermal expansion or contraction.
- the protective plate Y is composed of a plastic plate, a glass plate, or a semiconductor glass plate.
- the objective lens 2 is disposed below the opening 31b, and the observation object X is observed through the mounting member Z by the objective lens 2, and The plane Z ′ becomes the observation plane of the observation object X.
- a heater 4 is provided on the bottom surface of the first stage member 31.
- the heater 4 is disposed so as to surround the opening 3 lb.
- the heater 4 generates heat when energized, for example.
- This heater 4 functions as a heating means for heating the first stage member 31 and maintains the observation object X on the mounting member Z at a target temperature.
- the housing 1 and the second stage member 32 are made of a material having a low thermal conductivity, thermal expansion coefficient, and thermal contraction rate.
- the thermal expansion coefficient is low.
- Ishihide is the material
- resin is the material with low thermal conductivity.
- the first stage member 31 be made of a material having a high thermal conductivity so that the temperature can be adjusted effectively by the heater 4, for example, aluminum.
- the objective lens 2 can be moved in the direction of the arrow dl according to the operation of the observer by a mechanism (not shown), but may be moved by automatic control. By moving the objective lens 2 in the direction of the arrow dl, the distance between the observation object X and the objective lens 2 is adjusted and focusing is performed. Further, the objective lens 2 is provided with, for example, an image sensor such as a CCD or an optical fiber cable, so that an observation image from the objective lens 2 can be viewed on a monitor outside the apparatus.
- FIG. 2 is a partially enlarged view of the observation apparatus A in FIG. 1, and shows the positional relationship between the observation surface Z ′ and the upper surface of the mounting portion 32b (the contact surface between the first stage member 31 and the second stage member 32).
- the first stage member 31 is preferably a material having a high thermal conductivity so that the temperature can be easily adjusted by the heater 4.
- a material has a high thermal conductivity, and the material is generally heated. The coefficient of expansion and heat shrinkage tend to be high, and heat distortion is likely to occur.
- the neutral surface of the thermal strain of the first stage member 31 is the upper surface of the placement portion 32b.
- the observation surface Z ′ and the upper surface of the placement portion 32b are disposed on substantially the same horizontal plane. Therefore, the observation plane Z ′ is positioned on the neutral plane of the thermal strain of the first stage member 31.
- the thickness of the mounting member Z The bottom surface force of the recess 31a is also adjusted to the distance (height) to the line L1, or the depth of the bottom surface of the recess 3 la may be designed according to the thickness of the mounting member Z. .
- the observation surface Z ′ and the upper surface of the mounting portion 32b are preferably set on the same horizontal plane. For example, if the error is about several millimeters (more preferably about lmm), the focus is substantially out of focus. Because there is little influence, it should be on almost the same horizontal plane
- FIG. 3 is an external view of an observation apparatus B according to the second embodiment of the present invention.
- This observation apparatus B includes a housing 101, an objective lens (not shown) housed in the housing 101, and a stage unit 103 mounted on the upper surface of the housing 101.
- the casing 101 is provided with an operation unit 101a, for example, for adjusting the position of an objective lens (not shown in the figure).
- the housing 101 is provided with a power switch 101b.
- the stage unit 103 includes a first stage member 131 and a second stage member 132.
- the first stage member 131 includes a main body portion 1311, a holder 1312 that is detachably attached to the main body portion 1311, and a cover.
- the main body portion 1311 and the holder 1312 are made of a material having the same thermal expansion coefficient and thermal contraction rate. For example, they can have the same material force.
- FIG. 4 is a plan view of the observation apparatus B with the holder 1312 removed
- FIG. 5 is a plan view of the observation apparatus B with the first stage member 131 removed
- 6 is a cross-sectional view of the stage unit 103 taken along line XI-XI in FIG. 4
- FIG. 7 is a cross-sectional view of the stage unit 103 taken along line X2-X2 in FIG.
- the main body 1311 is a plate-like member having a concave section 131 la having a circular cross section opened upward. Honoreda 1312 ⁇ or 1311a ⁇ 1311a's bottom surface 1311a '[Opening hole 131 lb is provided, and this hole 131 lb penetrates the bottom surface of the main body 1311. On the inner peripheral surface 1311a of the recess 1311a, a bottom surface 1311a of the flange 1311a, and a groove 131lc that is directed upward from the force are formed.
- FIG. 8 is a cross-sectional view of the main body portion 1311 along the line X3-X3 in FIG. 4, and shows the configuration of the groove portion 1311c.
- the groove portion 1311c is provided to the periphery of the hole 131 lb, and air from below the main body portion 1311 can escape from the hole 131 lb through the groove portion 131 lc and above the main body portion 1311. .
- a plurality (four) of the grooves 1311c are provided, and these are arranged radially from the hole 131 lb.
- a heater 104 is provided on the bottom surface of the main body portion 1311.
- the heater 104 is disposed so as to surround the hole 131 lb, and generates heat when energized, for example.
- This heater 4 functions as a heating means for heating the entire first stage member 131, and maintains the observation object X in the holder 1312 described later at a target temperature. It is desirable that the main body 1311 and the holder 1312 are made of a material having high thermal conductivity so that the temperature can be adjusted effectively by the heater 104, for example, aluminum.
- the second stage member 132 is composed of a plate-like member having a circular opening 132a at the center thereof, and the main body 1311 of the first stage member 131 is placed around the opening 132a.
- a mounting portion 132b is formed.
- a plurality of protrusions 132c are formed on the upper surface of the mounting portion 132b, and the main body portion 1311 is mounted on the protruding portion 132c of the peripheral force of the bottom surface of the second stage member 132. Is supported horizontally. That is, the horizontal plane defined by the tips of the plurality of protrusions 132c is the contact surface between the first stage member 131 (main body portion 1311) and the second stage member 132.
- Holes 131 Id are provided at the four corners of the main body portion 1311, and screw holes 132d are provided at the four corners of the mounting portion 132b. Then, the main body 1311 is placed on the projection 132c, the Bonoleto 105 is inserted by the hole 131 Id force, and the main body 1311 is connected to the main hole 1311 by tying the hole 132d and the Bonoleto 105. The two-stage member 132 is fixed. Even when the main body portion 1311 is fixed to the second stage member 132, the bottom surface of the main body portion 1311 does not come into contact with the upper surface of the placement portion 132b because the protrusion 132c exists.
- the presence of the protrusion 132c The bottom surface of the main body 1311 and the second stage member 132 are in point contact, and the contact area between the two can be reduced. Thereby, the heat of the main body portion 1311 heated by the heater 104 becomes difficult to be transmitted to the second stage member 132, and the thermal strain of the second stage member 132 can be suppressed.
- the protrusion 132c may be formed integrally with the second stage member 132, or may be separately formed and attached to the second stage member 132.
- a material having a lower thermal conductivity than the first stage member 131 is desired, and a material having a particularly low thermal conductivity, such as a PEEK material, is desirable.
- a constant gap is provided between the two so that the side surface of the main body portion 1311 does not contact the second stage member 132.
- This is also a configuration for making it difficult for the heat of the main body portion 1311 to be transferred to the second stage member 132.
- the casing 101, the second stage member 132, and the bolt 105 are all made of a material having a low thermal conductivity, thermal expansion coefficient, and thermal contraction rate. Quartz is the material, and resin is a low thermal conductivity material.
- FIG. 9 is a main part sectional view showing the structure of the observation apparatus B, and is a main part sectional view taken along the same line as line X2-X2 of FIG.
- FIG. 9 shows that the holder 1312 is mounted on the main body 1311!
- the holoreda 1312 has a columnar shape as a whole, and is composed of an upper rod unit 1312a and a lower rod unit 1312d.
- the upper unit 1312a and the lower unit 1312d are configured to be separable, and both are fixed by a clamp mechanism (not shown) during use.
- a recess 1312a ′ having a circular cross section is formed at the center of the upper unit 1312a.
- a reagent or the like to be supplied to the observation object X is stored in the recess 1312a ′.
- the reagent inside the recess 1312a is supplied to the observation object X through a plurality of tubes 1312f extending from the bottom of the recess 1312a ′ to the bottom surface of the upper unit 1312a.
- a lid 1312b is detachably attached to the upper part of the recess 1312a '.
- a temperature sensor 1312c for detecting the temperature of the holder 1312 is provided on the upper surface of the holder 1312.
- the temperature sensor 1312c has a rod-shaped sensor portion 1312c, and the sensor portion 1312c extends through the recess 1312a ′ and below the recess 1312a. He mentioned above The temperature control of the main body portion 1311 and the holder 1312 by the heater 104 is performed based on the detection result of the temperature sensor 1312c.
- the lower unit 1312d has a substantially cylindrical shape, and a hole 1312d 'having a circular cross section is provided at the center of the bottom thereof.
- the hole 1312d ′ is a stepped hole whose upper part has a hole diameter larger than that of the lower part, and a placement member Z on which the observation object X is placed is set in the step part.
- the observation object X is stored in the concave portion of the plate-like holding member Y having a concave portion on the bottom surface and placed on the placement member Z.
- the mounting member Z is a transparent or translucent member, and is composed of, for example, a plastic plate or glass plate force that hardly causes thermal expansion or contraction.
- the holding member Y is composed of a plastic plate, a glass plate, or a semiconductor glass plate.
- the objective lens 102 is disposed below the holder 1312, that is, below the first stage member 131.
- the objective lens 102 may be moved by automatic force control that can be moved in the direction of the arrow d2 in accordance with an operation of the observer with respect to the operation unit 101a by a mechanism (not shown).
- the objective lens 102 is provided with, for example, an image sensor such as a CCD or an optical fiber cable, so that an observation image from the object lens 102 can be viewed on a monitor outside the apparatus.
- the objective lens 102 is disposed below the mounting member Z, and the observation object X is observed by the objective lens 102 through the mounting member Z. Is the observation surface Z ′ of the observation object X.
- the principle of prevention of focus deviation in this embodiment is the same as the principle of prevention of focus deviation in the observation apparatus A.
- the observation surface Z ′ and the tip of the protrusion 132c The defined horizontal plane (the contact surface between the first stage member 131 (main body portion 1311) and the second stage member 132) is set on substantially the same horizontal plane indicated by a broken line L2.
- the first stage member 131 is composed of a main body part 1311 and a holder 1312 that are separable from each other, and both are the same in thermal expansion coefficient and thermal contraction coefficient. Accordingly, as shown in FIG. 9, when the main body 1311 is heated by the heater 104 with the holder 1312 attached to the main body 1311, the holder 1312 is also heated by the heat conduction from the main body 1311, and The holder 1312 has almost the same amount of thermal strain.
- the first stage member Since the main body 1311 is placed and supported on the second stage member 132 (specifically, on the protrusion 132c), and the holder 1312 is mounted on the main body 1311, the first stage member
- the neutral surface of thermal strain of the entire 131 is the same horizontal plane as the horizontal plane defined by the tip of the protrusion 132c.
- the observation plane Z ′ and the horizontal plane defined by the tip of the protrusion 132c are set on substantially the same horizontal plane, so that the observation is performed on the neutral plane of the thermal strain of the first stage member 131.
- Surface Z ' is located.
- the first stage member 131 is composed of a main body portion 1311 and a holder 1312 that can be separated from each other, and the observation object X can be exchanged together with the holder 1312. A good experiment can be done.
- the groove 1311c is provided, so that the warm air heated by the heater 104 and the casing 101 are disposed below the first stage member 131 and around the objective lens 102. Warm air generated by various constituent forces (not shown) is exhausted above the first stage member 131 through the groove 1311c. Therefore, it is possible to suppress a situation where heat accumulates inside the casing 101 and causes thermal distortion of the casing 101 and the second stage member 102 or when the objective lens 102 is clouded.
- the horizontal plane defined by the observation surface Z 'and the tip of the protrusion 132c (the first stage member 131 (main body portion 1311) and the second stage member 132
- the thickness of the mounting member Z is designed to an appropriate thickness, or the protruding portion is set according to the thickness of the mounting member Z.
- the height of 132c should be designed.
- the observation plane Z ′ and the horizontal plane defined by the tip of the protrusion 132c (the contact surface between the first stage member 131 (main body portion 1311) and the second stage member 132) are set on the same horizontal plane.
- the error is about several millimeters (more preferably about lmm)
- the effect of defocusing is substantially small.
Abstract
Description
Claims
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2006539086A JP4550829B2 (ja) | 2004-09-30 | 2004-09-30 | 観察装置のステージユニット及び観察装置 |
EP04788367A EP1795940B1 (en) | 2004-09-30 | 2004-09-30 | Monitoring device and stage unit |
PCT/JP2004/014339 WO2006038255A1 (ja) | 2004-09-30 | 2004-09-30 | 観察装置及びステージユニット |
US11/663,092 US20070291352A1 (en) | 2004-09-30 | 2004-09-30 | Monitoring Device and Stage Unit |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/JP2004/014339 WO2006038255A1 (ja) | 2004-09-30 | 2004-09-30 | 観察装置及びステージユニット |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2006038255A1 true WO2006038255A1 (ja) | 2006-04-13 |
Family
ID=36142346
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2004/014339 WO2006038255A1 (ja) | 2004-09-30 | 2004-09-30 | 観察装置及びステージユニット |
Country Status (4)
Country | Link |
---|---|
US (1) | US20070291352A1 (ja) |
EP (1) | EP1795940B1 (ja) |
JP (1) | JP4550829B2 (ja) |
WO (1) | WO2006038255A1 (ja) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2013213855A (ja) * | 2012-03-30 | 2013-10-17 | Olympus Corp | ステージ構造体および倒立型顕微鏡 |
JP2016194550A (ja) * | 2015-03-31 | 2016-11-17 | キヤノン株式会社 | ステージ装置および顕微鏡 |
JP2016194549A (ja) * | 2015-03-31 | 2016-11-17 | キヤノン株式会社 | ステージ装置および顕微鏡 |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW201716825A (zh) * | 2015-11-13 | 2017-05-16 | 億觀生物科技股份有限公司 | 顯微鏡單元及顯微鏡裝置 |
WO2020056291A1 (en) * | 2018-09-14 | 2020-03-19 | University Of Massachusetts | Heated stage assembly for high temperature fluorescence microscopy |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0029238A1 (de) | 1979-11-17 | 1981-05-27 | Firma Carl Zeiss | Objekthaltersystem für aufrechte Mikroskope |
US6160662A (en) | 1998-05-29 | 2000-12-12 | Nikon Corporation | Inverted microscope having a variable stage position |
US6233093B1 (en) | 1997-11-25 | 2001-05-15 | The Goodyear Tire & Rubber Company | Temperature control for microscopy |
JP2002098909A (ja) * | 2000-09-26 | 2002-04-05 | Tokai Hit:Kk | 顕微鏡観察用温度管理器の本体部 |
JP2002207175A (ja) * | 2001-01-04 | 2002-07-26 | Olympus Optical Co Ltd | 顕微鏡 |
JP2003050358A (ja) * | 2001-08-07 | 2003-02-21 | Tokai Hit:Kk | 検体温度管理器の本体部 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4589741A (en) * | 1984-12-21 | 1986-05-20 | Clegg John E | Universal revolving microscope stage |
US5257128A (en) * | 1988-06-22 | 1993-10-26 | Board Of Regents, The University Of Texas System | Freezing/perfusion microscope stage |
US5181382A (en) * | 1991-08-02 | 1993-01-26 | Middlebrook Thomas F | Heating/cooling or warming stage assembly with coverslip chamber assembly and perfusion fluid preheater/cooler assembly |
JP2743913B2 (ja) * | 1996-06-07 | 1998-04-28 | 日本電気株式会社 | 工程手順検証装置 |
JP3885305B2 (ja) * | 1997-08-27 | 2007-02-21 | 株式会社ニコン | 倒立顕微鏡 |
US7180662B2 (en) * | 2004-04-12 | 2007-02-20 | Applied Scientific Instrumentation Inc. | Stage assembly and method for optical microscope including Z-axis stage and piezoelectric actuator for rectilinear translation of Z stage |
-
2004
- 2004-09-30 EP EP04788367A patent/EP1795940B1/en not_active Expired - Fee Related
- 2004-09-30 JP JP2006539086A patent/JP4550829B2/ja not_active Expired - Fee Related
- 2004-09-30 US US11/663,092 patent/US20070291352A1/en not_active Abandoned
- 2004-09-30 WO PCT/JP2004/014339 patent/WO2006038255A1/ja active Application Filing
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0029238A1 (de) | 1979-11-17 | 1981-05-27 | Firma Carl Zeiss | Objekthaltersystem für aufrechte Mikroskope |
US6233093B1 (en) | 1997-11-25 | 2001-05-15 | The Goodyear Tire & Rubber Company | Temperature control for microscopy |
US6160662A (en) | 1998-05-29 | 2000-12-12 | Nikon Corporation | Inverted microscope having a variable stage position |
JP2002098909A (ja) * | 2000-09-26 | 2002-04-05 | Tokai Hit:Kk | 顕微鏡観察用温度管理器の本体部 |
JP2002207175A (ja) * | 2001-01-04 | 2002-07-26 | Olympus Optical Co Ltd | 顕微鏡 |
JP2003050358A (ja) * | 2001-08-07 | 2003-02-21 | Tokai Hit:Kk | 検体温度管理器の本体部 |
Non-Patent Citations (1)
Title |
---|
See also references of EP1795940A4 |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2013213855A (ja) * | 2012-03-30 | 2013-10-17 | Olympus Corp | ステージ構造体および倒立型顕微鏡 |
JP2016194550A (ja) * | 2015-03-31 | 2016-11-17 | キヤノン株式会社 | ステージ装置および顕微鏡 |
JP2016194549A (ja) * | 2015-03-31 | 2016-11-17 | キヤノン株式会社 | ステージ装置および顕微鏡 |
Also Published As
Publication number | Publication date |
---|---|
EP1795940B1 (en) | 2012-06-13 |
EP1795940A4 (en) | 2010-01-06 |
US20070291352A1 (en) | 2007-12-20 |
JPWO2006038255A1 (ja) | 2008-05-15 |
EP1795940A1 (en) | 2007-06-13 |
JP4550829B2 (ja) | 2010-09-22 |
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