WO2005107809A8 - Composition pharmaceutique antimycobacterienne - Google Patents

Composition pharmaceutique antimycobacterienne

Info

Publication number
WO2005107809A8
WO2005107809A8 PCT/IN2004/000266 IN2004000266W WO2005107809A8 WO 2005107809 A8 WO2005107809 A8 WO 2005107809A8 IN 2004000266 W IN2004000266 W IN 2004000266W WO 2005107809 A8 WO2005107809 A8 WO 2005107809A8
Authority
WO
WIPO (PCT)
Prior art keywords
pharmaceutical composition
antimycobacterial
antitubercular drug
antimycobacterial pharmaceutical
methyl
Prior art date
Application number
PCT/IN2004/000266
Other languages
English (en)
Other versions
WO2005107809A3 (fr
WO2005107809A2 (fr
Inventor
Sudershan Kumar Arora
Neelima Sinha
Rakesh Sinha
Ram Shankar Upadhyaya
Original Assignee
Lupin Ltd
Sudershan Kumar Arora
Neelima Sinha
Rakesh Sinha
Ram Shankar Upadhyaya
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to EA200601952A priority Critical patent/EA009694B1/ru
Priority to CN2004800431312A priority patent/CN1956732B/zh
Application filed by Lupin Ltd, Sudershan Kumar Arora, Neelima Sinha, Rakesh Sinha, Ram Shankar Upadhyaya filed Critical Lupin Ltd
Priority to MXPA06012984A priority patent/MXPA06012984A/es
Priority to DE602004009113T priority patent/DE602004009113T2/de
Priority to UAA200612258A priority patent/UA82782C2/uk
Priority to BRPI0418770-9A priority patent/BRPI0418770A/pt
Priority to DK04816650T priority patent/DK1750765T3/da
Priority to CA002566440A priority patent/CA2566440C/fr
Priority to EP04816650A priority patent/EP1750765B1/fr
Priority to JP2007512723A priority patent/JP2007537242A/ja
Priority to YUP-2006/0624A priority patent/RS20060624A/sr
Priority to AP2006003807A priority patent/AP1994A/xx
Priority to PL04816650T priority patent/PL1750765T3/pl
Priority to NZ550892A priority patent/NZ550892A/en
Priority to AU2004319259A priority patent/AU2004319259A1/en
Publication of WO2005107809A2 publication Critical patent/WO2005107809A2/fr
Publication of WO2005107809A3 publication Critical patent/WO2005107809A3/fr
Publication of WO2005107809A8 publication Critical patent/WO2005107809A8/fr
Priority to IL178858A priority patent/IL178858A/en
Priority to IS8559A priority patent/IS8559A/is
Priority to TNP2006000349A priority patent/TNSN06349A1/en
Priority to NO20065725A priority patent/NO20065725L/no
Priority to HK07106405A priority patent/HK1098962A1/xx
Priority to HR20070574T priority patent/HRP20070574T3/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/131—Amines acyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4409—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 4, e.g. isoniazid, iproniazid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/49—Cinchonan derivatives, e.g. quinine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

La présente invention concerne d'une combinaison d'une composition antimycobactérienne destinée à traiter la tuberculose. Les composés utilisés sont N-(3-[[4-(3-trifluorométhylphényl)piperazinyl]méthyl]-2-méthyl-5-phényl-pyrrolyl)-4-pyridylcarboxamide représentés par la formule (I) ou un sel non toxique répondant aux normes pharmaceutiques de ces composés et une quantité d'un ou de plusieurs médicaments antituberculeux de première lignée.
PCT/IN2004/000266 2004-05-12 2004-08-27 Composition pharmaceutique antimycobacterienne WO2005107809A2 (fr)

Priority Applications (21)

Application Number Priority Date Filing Date Title
PL04816650T PL1750765T3 (pl) 2004-05-12 2004-08-27 Przeciwprątkowa kompozycja farmaceutyczna zawierająca lek przeciwgruźliczy
AP2006003807A AP1994A (en) 2004-05-12 2004-08-27 An antimycobacterial pharmaceutical composition
MXPA06012984A MXPA06012984A (es) 2004-05-12 2004-08-27 Una composicion farmaceutica antimicobacteriana.
CN2004800431312A CN1956732B (zh) 2004-05-12 2004-08-27 含有抗结核药物的抗分支杆菌药物组合物
UAA200612258A UA82782C2 (uk) 2004-05-12 2004-08-27 Антимікобактеріальна фармакологічна композиція та спосіб її одержання
BRPI0418770-9A BRPI0418770A (pt) 2004-05-12 2004-08-27 combinação antimicobacteriana, composição farmacêutica antimicobacteriana e processo para a preparação de uma composição farmacêutica antimicobacteriana
NZ550892A NZ550892A (en) 2004-05-12 2004-08-27 Antimycobacterial pharmaceutical composition comprising an antitubercular drug
CA002566440A CA2566440C (fr) 2004-05-12 2004-08-27 Composition pharmaceutique antimycobacterienne
EP04816650A EP1750765B1 (fr) 2004-05-12 2004-08-27 Composition pharmaceutique antimycobacterienne comprenant un medicament antituberculeux
JP2007512723A JP2007537242A (ja) 2004-05-12 2004-08-27 抗マイコバクテリア医薬組成物
YUP-2006/0624A RS20060624A (en) 2004-05-12 2004-08-27 Antimycobacterial pharmaceutical composition
EA200601952A EA009694B1 (ru) 2004-05-12 2004-08-27 Антимикобактериальная фармакологическая композиция
DE602004009113T DE602004009113T2 (de) 2004-05-12 2004-08-27 Antimykobakterielle pharmazeutische zusammensetzung mit einem arzneimittel gegen tuberkulose
DK04816650T DK1750765T3 (da) 2004-05-12 2004-08-27 Farmaceutisk antimykobakteriesammensætning omfattende et antituberkulöst lægemiddel
AU2004319259A AU2004319259A1 (en) 2004-05-12 2004-08-27 Antimycobacterial pharmaceutical composition comprising an antitubercular drug
IL178858A IL178858A (en) 2004-05-12 2006-10-25 Antimycobacterial pharmaceutical composition comprising an antitubercular drug
IS8559A IS8559A (is) 2004-05-12 2006-10-26 Lyfjasamsetning gegn sveppagerlum
TNP2006000349A TNSN06349A1 (en) 2004-05-12 2006-10-30 An antimycobacterial pharmaceutical composition
NO20065725A NO20065725L (no) 2004-05-12 2006-12-12 En antimycobakteriell farmasoytisk sammensetning.
HK07106405A HK1098962A1 (en) 2004-05-12 2007-06-14 Antimycobacterial pharmaceutical composition comprising an antitubercular drug
HR20070574T HRP20070574T3 (en) 2004-05-12 2007-12-19 Antimycobacterial pharmaceutical composition comprising an antitubercular drug

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/844,992 US7491721B2 (en) 2004-05-12 2004-05-12 Antimycobacterial pharmaceutical composition
US10/844,992 2004-05-12

Publications (3)

Publication Number Publication Date
WO2005107809A2 WO2005107809A2 (fr) 2005-11-17
WO2005107809A3 WO2005107809A3 (fr) 2006-01-26
WO2005107809A8 true WO2005107809A8 (fr) 2006-05-18

Family

ID=34960626

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2004/000266 WO2005107809A2 (fr) 2004-05-12 2004-08-27 Composition pharmaceutique antimycobacterienne

Country Status (45)

Country Link
US (1) US7491721B2 (fr)
EP (1) EP1750765B1 (fr)
JP (1) JP2007537242A (fr)
KR (1) KR100854309B1 (fr)
CN (1) CN1956732B (fr)
AP (1) AP1994A (fr)
AR (1) AR048948A1 (fr)
AT (1) ATE373488T1 (fr)
AU (1) AU2004319259A1 (fr)
BR (1) BRPI0418770A (fr)
CA (1) CA2566440C (fr)
CR (1) CR8748A (fr)
DE (1) DE602004009113T2 (fr)
DK (1) DK1750765T3 (fr)
DO (1) DOP2005000085A (fr)
EA (1) EA009694B1 (fr)
EC (1) ECSP066965A (fr)
ES (1) ES2294577T3 (fr)
GE (1) GEP20094805B (fr)
HK (1) HK1098962A1 (fr)
HN (1) HN2005000210A (fr)
HR (1) HRP20070574T3 (fr)
IL (1) IL178858A (fr)
IS (1) IS8559A (fr)
JO (1) JO2471B1 (fr)
MA (1) MA28603B1 (fr)
MX (1) MXPA06012984A (fr)
MY (1) MY139187A (fr)
NI (1) NI200600270A (fr)
NO (1) NO20065725L (fr)
NZ (1) NZ550892A (fr)
PA (1) PA8633001A1 (fr)
PE (1) PE20060353A1 (fr)
PL (1) PL1750765T3 (fr)
PT (1) PT1750765E (fr)
RS (1) RS20060624A (fr)
SA (1) SA05260130B1 (fr)
SI (1) SI1750765T1 (fr)
SM (1) SM200500011A (fr)
SV (1) SV2006002109A (fr)
TN (1) TNSN06349A1 (fr)
UA (1) UA82782C2 (fr)
UY (1) UY28893A1 (fr)
WO (1) WO2005107809A2 (fr)
ZA (1) ZA200608843B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006109323A1 (fr) * 2005-04-11 2006-10-19 Lupin Limited Préparation de dérivés de [2-méthyl-5-phényl-3-(pipérazine-1-ylméthyl)] pyrrole
JP5339840B2 (ja) * 2008-10-02 2013-11-13 公益財団法人微生物化学研究会 抗ｘｄｒ−ｔｂ薬、抗ｍｄｒ−ｔｂ薬、及び併用抗結核薬
US9198913B2 (en) * 2009-07-31 2015-12-01 Global Alliance For Tb Drug Development Nitroimidazooxazines and their uses in anti-tubercular therapy
AU2010292148A1 (en) * 2009-09-11 2012-04-12 Vertex Pharmaceuticals Incorporated Compositions of N-benzyl-3-(4-chlorophenyl)-2- [methyl-[2-oxo-2-(3,4,5-trimethoxyphenyl) acetyl]amino]-N- [3-(4-pyridyl)-1-[2-[4-pyridyl)ethy]propyl]propanamide and uses thereof
HUP1000033A2 (en) * 2010-01-21 2011-07-28 Uratim Kft Piperazine derivatives useful against mycobacteriums
KR102462751B1 (ko) * 2021-10-20 2022-11-03 순천향대학교 산학협력단 신규한 페디오코커스 균주 및 이를 포함하는 결핵 예방, 치료, 또는 개선용 조성물
US11977085B1 (en) 2023-09-05 2024-05-07 Elan Ehrlich Date rape drug detection device and method of using same

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5227383A (en) * 1991-06-14 1993-07-13 The University Of Mississippi Compounds and compositions useful as antifungal and antimycobacterial agents
JP2006503837A (ja) * 2002-09-20 2006-02-02 ルピン・リミテッド 新規の抗マイコバクテリア化合物

Also Published As

Publication number Publication date
NZ550892A (en) 2009-12-24
SV2006002109A (es) 2006-04-18
EP1750765A2 (fr) 2007-02-14
ATE373488T1 (de) 2007-10-15
CA2566440A1 (fr) 2005-11-17
SM200500011B (it) 2005-11-16
DE602004009113T2 (de) 2008-06-19
CN1956732A (zh) 2007-05-02
US7491721B2 (en) 2009-02-17
PA8633001A1 (es) 2006-12-07
HK1098962A1 (en) 2007-08-03
NO20065725L (no) 2006-12-12
MY139187A (en) 2009-08-28
WO2005107809A3 (fr) 2006-01-26
IS8559A (is) 2006-10-26
IL178858A0 (en) 2007-03-08
KR100854309B1 (ko) 2008-08-26
CN1956732B (zh) 2010-04-28
UA82782C2 (uk) 2008-05-12
WO2005107809A2 (fr) 2005-11-17
PT1750765E (pt) 2007-12-31
MA28603B1 (fr) 2007-05-02
DOP2005000085A (es) 2007-01-15
ES2294577T3 (es) 2008-04-01
BRPI0418770A (pt) 2007-10-09
SA05260130B1 (ar) 2008-05-04
TNSN06349A1 (en) 2008-02-22
AR048948A1 (es) 2006-06-14
SM200500011A (it) 2005-11-16
UY28893A1 (es) 2005-12-30
KR20070007920A (ko) 2007-01-16
EP1750765B1 (fr) 2007-09-19
ZA200608843B (en) 2008-07-30
MXPA06012984A (es) 2007-04-23
NI200600270A (es) 2007-12-11
AP1994A (en) 2009-04-09
RS20060624A (en) 2008-09-29
CR8748A (es) 2008-06-02
GEP20094805B (en) 2009-10-26
SI1750765T1 (sl) 2008-04-30
US20050256128A1 (en) 2005-11-17
IL178858A (en) 2010-06-16
AU2004319259A1 (en) 2005-11-17
HRP20070574T3 (en) 2008-01-31
JP2007537242A (ja) 2007-12-20
HN2005000210A (es) 2009-03-17
EA200601952A1 (ru) 2007-02-27
ECSP066965A (es) 2006-12-20
DK1750765T3 (da) 2008-01-28
EA009694B1 (ru) 2008-02-28
AP2006003807A0 (en) 2006-12-31
CA2566440C (fr) 2009-08-04
JO2471B1 (en) 2009-01-20
DE602004009113D1 (de) 2007-10-31
PL1750765T3 (pl) 2008-02-29
PE20060353A1 (es) 2006-07-08

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