ECSP066965A - Una composicion farmacéutica antibacterial - Google Patents

Una composicion farmacéutica antibacterial

Info

Publication number
ECSP066965A
ECSP066965A EC2006006965A ECSP066965A ECSP066965A EC SP066965 A ECSP066965 A EC SP066965A EC 2006006965 A EC2006006965 A EC 2006006965A EC SP066965 A ECSP066965 A EC SP066965A EC SP066965 A ECSP066965 A EC SP066965A
Authority
EC
Ecuador
Prior art keywords
pharmaceutical composition
antibacterial pharmaceutical
methyl
formula
composition
Prior art date
Application number
EC2006006965A
Other languages
English (en)
Inventor
Sudershan Kumar Arora
Neelima Sinha
Ram Shankar Upadhayaya
Rakesh Kumar Sinha
Original Assignee
Lupin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lupin Ltd filed Critical Lupin Ltd
Publication of ECSP066965A publication Critical patent/ECSP066965A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/131Amines acyclic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4409Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 4, e.g. isoniazid, iproniazid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/49Cinchonan derivatives, e.g. quinine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965Non-condensed pyrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • A61P31/06Antibacterial agents for tuberculosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

Se describe una combinación antimicrobacteriana y una composición para tratar la tuberculosis. Los compuestos usados son N-3-[[4-3-trifluorometilfenil)piperacinil]metil]-2-(metil-5-fenil-pirrolil)-4-piridilcarboxamida de fórmula I o una sal farmacéuticamente aceptable por tanto no tóxica, y una cantidad de uno o mas fármacos antituberculosas de primera línea.FORMULA I:
EC2006006965A 2004-05-12 2006-10-30 Una composicion farmacéutica antibacterial ECSP066965A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10/844,992 US7491721B2 (en) 2004-05-12 2004-05-12 Antimycobacterial pharmaceutical composition

Publications (1)

Publication Number Publication Date
ECSP066965A true ECSP066965A (es) 2006-12-20

Family

ID=34960626

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2006006965A ECSP066965A (es) 2004-05-12 2006-10-30 Una composicion farmacéutica antibacterial

Country Status (45)

Country Link
US (1) US7491721B2 (es)
EP (1) EP1750765B1 (es)
JP (1) JP2007537242A (es)
KR (1) KR100854309B1 (es)
CN (1) CN1956732B (es)
AP (1) AP1994A (es)
AR (1) AR048948A1 (es)
AT (1) ATE373488T1 (es)
AU (1) AU2004319259A1 (es)
BR (1) BRPI0418770A (es)
CA (1) CA2566440C (es)
CR (1) CR8748A (es)
DE (1) DE602004009113T2 (es)
DK (1) DK1750765T3 (es)
DO (1) DOP2005000085A (es)
EA (1) EA009694B1 (es)
EC (1) ECSP066965A (es)
ES (1) ES2294577T3 (es)
GE (1) GEP20094805B (es)
HK (1) HK1098962A1 (es)
HN (1) HN2005000210A (es)
HR (1) HRP20070574T3 (es)
IL (1) IL178858A (es)
IS (1) IS8559A (es)
JO (1) JO2471B1 (es)
MA (1) MA28603B1 (es)
MX (1) MXPA06012984A (es)
MY (1) MY139187A (es)
NI (1) NI200600270A (es)
NO (1) NO20065725L (es)
NZ (1) NZ550892A (es)
PA (1) PA8633001A1 (es)
PE (1) PE20060353A1 (es)
PL (1) PL1750765T3 (es)
PT (1) PT1750765E (es)
RS (1) RS20060624A (es)
SA (1) SA05260130B1 (es)
SI (1) SI1750765T1 (es)
SM (1) SM200500011B (es)
SV (1) SV2006002109A (es)
TN (1) TNSN06349A1 (es)
UA (1) UA82782C2 (es)
UY (1) UY28893A1 (es)
WO (1) WO2005107809A2 (es)
ZA (1) ZA200608843B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1871742A1 (en) * 2005-04-11 2008-01-02 Lupin Ltd. Preparation of ý2-methyl-5-phenyl-3-(piperazin-1-ylmethyl)¨pyrrole derivatives
JP5339840B2 (ja) * 2008-10-02 2013-11-13 公益財団法人微生物化学研究会 抗xdr−tb薬、抗mdr−tb薬、及び併用抗結核薬
US9198913B2 (en) * 2009-07-31 2015-12-01 Global Alliance For Tb Drug Development Nitroimidazooxazines and their uses in anti-tubercular therapy
CN102655865A (zh) * 2009-09-11 2012-09-05 沃泰克斯药物股份有限公司 N-苄基-3-(4-氯苯基)-2-[甲基-[2-氧代-2-(3,4,5-三甲氧基苯基)乙酰基]氨基]-n-[3-(4-吡啶基)-1-[2-(4-吡啶基)乙基]丙酰胺的组合物及其用途
HUP1000033A2 (en) * 2010-01-21 2011-07-28 Uratim Kft Piperazine derivatives useful against mycobacteriums
KR102462751B1 (ko) * 2021-10-20 2022-11-03 순천향대학교 산학협력단 신규한 페디오코커스 균주 및 이를 포함하는 결핵 예방, 치료, 또는 개선용 조성물
US11977085B1 (en) 2023-09-05 2024-05-07 Elan Ehrlich Date rape drug detection device and method of using same

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5227383A (en) * 1991-06-14 1993-07-13 The University Of Mississippi Compounds and compositions useful as antifungal and antimycobacterial agents
US7691837B2 (en) * 2002-09-20 2010-04-06 Lupin Limited Pyrrole derivatives as antimycobacterial compounds

Also Published As

Publication number Publication date
NZ550892A (en) 2009-12-24
CR8748A (es) 2008-06-02
AP1994A (en) 2009-04-09
AP2006003807A0 (en) 2006-12-31
NO20065725L (no) 2006-12-12
EP1750765B1 (en) 2007-09-19
EA200601952A1 (ru) 2007-02-27
PE20060353A1 (es) 2006-07-08
GEP20094805B (en) 2009-10-26
IL178858A0 (en) 2007-03-08
PT1750765E (pt) 2007-12-31
KR20070007920A (ko) 2007-01-16
MY139187A (en) 2009-08-28
IS8559A (is) 2006-10-26
DOP2005000085A (es) 2007-01-15
DE602004009113D1 (de) 2007-10-31
DE602004009113T2 (de) 2008-06-19
CN1956732A (zh) 2007-05-02
DK1750765T3 (da) 2008-01-28
BRPI0418770A (pt) 2007-10-09
EP1750765A2 (en) 2007-02-14
AR048948A1 (es) 2006-06-14
CA2566440A1 (en) 2005-11-17
AU2004319259A1 (en) 2005-11-17
SV2006002109A (es) 2006-04-18
CA2566440C (en) 2009-08-04
US7491721B2 (en) 2009-02-17
ES2294577T3 (es) 2008-04-01
MXPA06012984A (es) 2007-04-23
IL178858A (en) 2010-06-16
TNSN06349A1 (en) 2008-02-22
CN1956732B (zh) 2010-04-28
KR100854309B1 (ko) 2008-08-26
US20050256128A1 (en) 2005-11-17
JP2007537242A (ja) 2007-12-20
HN2005000210A (es) 2009-03-17
RS20060624A (en) 2008-09-29
HK1098962A1 (en) 2007-08-03
MA28603B1 (fr) 2007-05-02
SI1750765T1 (sl) 2008-04-30
NI200600270A (es) 2007-12-11
JO2471B1 (en) 2009-01-20
PA8633001A1 (es) 2006-12-07
WO2005107809A3 (en) 2006-01-26
WO2005107809A8 (en) 2006-05-18
SA05260130B1 (ar) 2008-05-04
UA82782C2 (uk) 2008-05-12
SM200500011A (it) 2005-11-16
ATE373488T1 (de) 2007-10-15
HRP20070574T3 (en) 2008-01-31
EA009694B1 (ru) 2008-02-28
SM200500011B (it) 2005-11-16
WO2005107809A2 (en) 2005-11-17
ZA200608843B (en) 2008-07-30
UY28893A1 (es) 2005-12-30
PL1750765T3 (pl) 2008-02-29

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