WO2003072820A3 - Methode et acides nucleiques permettant d'analyser les troubles associes a la proliferation des cellules du colon - Google Patents

Methode et acides nucleiques permettant d'analyser les troubles associes a la proliferation des cellules du colon Download PDF

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Publication number
WO2003072820A3
WO2003072820A3 PCT/EP2003/002034 EP0302034W WO03072820A3 WO 2003072820 A3 WO2003072820 A3 WO 2003072820A3 EP 0302034 W EP0302034 W EP 0302034W WO 03072820 A3 WO03072820 A3 WO 03072820A3
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WO
WIPO (PCT)
Prior art keywords
cell proliferative
analysis
nucleic acids
proliferative disorders
colon cell
Prior art date
Application number
PCT/EP2003/002034
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English (en)
Other versions
WO2003072820A2 (fr
Inventor
Peter Adorjan
Matthias Burger
Sabine Maier
Ralf Lesche
Susan Cottrell
Suzanne Mooney
Original Assignee
Epigenomics Ag
Peter Adorjan
Matthias Burger
Sabine Maier
Ralf Lesche
Susan Cottrell
Suzanne Mooney
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Epigenomics Ag, Peter Adorjan, Matthias Burger, Sabine Maier, Ralf Lesche, Susan Cottrell, Suzanne Mooney filed Critical Epigenomics Ag
Priority to US10/506,089 priority Critical patent/US20060234224A1/en
Priority to AT03742964T priority patent/ATE491038T1/de
Priority to EP03742964A priority patent/EP1481095B1/fr
Priority to DE60335245T priority patent/DE60335245D1/de
Priority to JP2003571500A priority patent/JP2005518219A/ja
Priority to AU2003248349A priority patent/AU2003248349B2/en
Publication of WO2003072820A2 publication Critical patent/WO2003072820A2/fr
Publication of WO2003072820A3 publication Critical patent/WO2003072820A3/fr
Priority to US12/794,449 priority patent/US9988683B2/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/154—Methylation markers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)

Abstract

L'invention concerne des méthodes et des acides nucléiques de détection, de différenciation, ou de distinction des troubles associés à la prolifération des cellules du côlon par analyse d'un ou de plusieurs des gènes Versican, TPEF, H-Cadhérine, Calcitonine, et EYA4. L'invention concerne également de nouvelles séquences d'acide nucléique utilisées dans l'analyse spécifique des troubles associés à la prolifération des cellules du côlon desdits gènes, ainsi que des méthodes, des dosages et des kits.
PCT/EP2003/002034 2002-02-27 2003-02-27 Methode et acides nucleiques permettant d'analyser les troubles associes a la proliferation des cellules du colon WO2003072820A2 (fr)

Priority Applications (7)

Application Number Priority Date Filing Date Title
US10/506,089 US20060234224A1 (en) 2002-02-27 2003-02-27 Method and nucleic acids for the analysis of colon cell proliferative disorders
AT03742964T ATE491038T1 (de) 2002-02-27 2003-02-27 Verfahren und nukleinsäuren zur analyse von kolonkrebs
EP03742964A EP1481095B1 (fr) 2002-02-27 2003-02-27 Methode et acides nucleiques permettant d'analyser les troubles associes a la proliferation des cellules du colon
DE60335245T DE60335245D1 (de) 2002-02-27 2003-02-27 Verfahren und nukleinsäuren zur analyse von kolonkrebs
JP2003571500A JP2005518219A (ja) 2002-02-27 2003-02-27 結腸細胞増殖性疾患を分析するための方法および核酸
AU2003248349A AU2003248349B2 (en) 2002-02-27 2003-02-27 Method and nucleic acids for the analysis of colon cell proliferative disorders
US12/794,449 US9988683B2 (en) 2002-02-27 2010-06-04 Method and nucleic acids for the analysis of colon cell proliferative disorders

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02004551A EP1340818A1 (fr) 2002-02-27 2002-02-27 Procédés et acides nucléiques pour l'analyse d'un trouble associé à la prolifération de cellules du colon
EP02004551.4 2002-02-27

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US10506089 A-371-Of-International 2003-02-27
US12/794,449 Continuation US9988683B2 (en) 2002-02-27 2010-06-04 Method and nucleic acids for the analysis of colon cell proliferative disorders

Publications (2)

Publication Number Publication Date
WO2003072820A2 WO2003072820A2 (fr) 2003-09-04
WO2003072820A3 true WO2003072820A3 (fr) 2004-04-08

Family

ID=27675653

Family Applications (3)

Application Number Title Priority Date Filing Date
PCT/EP2003/001457 WO2003072812A2 (fr) 2002-02-27 2003-02-13 Methode et acides nucleiques pour l'analyse de troubles de la proliferation cellulaire colorectale
PCT/EP2003/002035 WO2003072821A2 (fr) 2002-02-27 2003-02-27 Procede et acides nucleiques permettant l'analyse d'un trouble proliferatif des cellules du colon
PCT/EP2003/002034 WO2003072820A2 (fr) 2002-02-27 2003-02-27 Methode et acides nucleiques permettant d'analyser les troubles associes a la proliferation des cellules du colon

Family Applications Before (2)

Application Number Title Priority Date Filing Date
PCT/EP2003/001457 WO2003072812A2 (fr) 2002-02-27 2003-02-13 Methode et acides nucleiques pour l'analyse de troubles de la proliferation cellulaire colorectale
PCT/EP2003/002035 WO2003072821A2 (fr) 2002-02-27 2003-02-27 Procede et acides nucleiques permettant l'analyse d'un trouble proliferatif des cellules du colon

Country Status (9)

Country Link
US (6) US8691503B2 (fr)
EP (4) EP1340818A1 (fr)
JP (3) JP2005518218A (fr)
AT (3) ATE376596T1 (fr)
AU (3) AU2003210265A1 (fr)
CA (1) CA2451982A1 (fr)
DE (3) DE60317045T2 (fr)
ES (2) ES2295607T3 (fr)
WO (3) WO2003072812A2 (fr)

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Also Published As

Publication number Publication date
WO2003072821A3 (fr) 2004-04-01
WO2003072812A2 (fr) 2003-09-04
EP1478778A2 (fr) 2004-11-24
EP1481095B1 (fr) 2010-12-08
US20060246433A1 (en) 2006-11-02
US9988683B2 (en) 2018-06-05
US20140179563A1 (en) 2014-06-26
DE60335245D1 (de) 2011-01-20
US20050003463A1 (en) 2005-01-06
WO2003072820A2 (fr) 2003-09-04
ES2325363T3 (es) 2009-09-02
JP2005518218A (ja) 2005-06-23
ATE376596T1 (de) 2007-11-15
WO2003072812A3 (fr) 2003-10-23
AU2003210265A1 (en) 2003-09-09
US20150275312A1 (en) 2015-10-01
US20110046005A1 (en) 2011-02-24
EP1478784B1 (fr) 2007-10-24
DE60327600D1 (de) 2009-06-25
ES2295607T3 (es) 2008-04-16
US8691503B2 (en) 2014-04-08
JP2005518219A (ja) 2005-06-23
EP1478778B1 (fr) 2009-05-13
AU2003219002A1 (en) 2003-09-09
EP1340818A1 (fr) 2003-09-03
DE60317045D1 (de) 2007-12-06
EP1478784A2 (fr) 2004-11-24
AU2003219002B2 (en) 2008-04-24
AU2003248349A1 (en) 2003-09-09
ATE431429T1 (de) 2009-05-15
WO2003072821A2 (fr) 2003-09-04
AU2003248349B2 (en) 2008-05-01
ATE491038T1 (de) 2010-12-15
US20060234224A1 (en) 2006-10-19
CA2451982A1 (fr) 2003-09-04
JP2005518220A (ja) 2005-06-23
DE60317045T2 (de) 2008-08-07
EP1481095A2 (fr) 2004-12-01

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