WO2003070721A1 - 2-(2-pyridyl)-5-phenyl-6-aminopyrimidine, verfahren und zwischenprodukte zu ihrer herstellung und ihre verwendung zur bekämpfung von schadpilzen - Google Patents

2-(2-pyridyl)-5-phenyl-6-aminopyrimidine, verfahren und zwischenprodukte zu ihrer herstellung und ihre verwendung zur bekämpfung von schadpilzen Download PDF

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Publication number
WO2003070721A1
WO2003070721A1 PCT/EP2003/001162 EP0301162W WO03070721A1 WO 2003070721 A1 WO2003070721 A1 WO 2003070721A1 EP 0301162 W EP0301162 W EP 0301162W WO 03070721 A1 WO03070721 A1 WO 03070721A1
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WO
WIPO (PCT)
Prior art keywords
alkyl
formula
halogen
methyl
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2003/001162
Other languages
German (de)
English (en)
French (fr)
Inventor
Frank Schieweck
Jordi Tormo I Blasco
Thomas Grote
Andreas Gypser
Bernd Müller
Joachim Rheinheimer
Ingo Rose
Peter Schäfer
Wassilios Grammenos
Markus Gewehr
Anja Schwögler
Carsten Blettner
Eberhard Ammermann
Siegfried Strathmann
Gisela Lorenz
Reinhard Stierl
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
BASF SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2002110136 external-priority patent/DE10210136A1/de
Application filed by BASF SE filed Critical BASF SE
Priority to US10/505,146 priority Critical patent/US7320975B2/en
Priority to EP03742510A priority patent/EP1504001B1/de
Priority to JP2003569628A priority patent/JP2005523286A/ja
Priority to DE50311420T priority patent/DE50311420D1/de
Priority to AU2003210217A priority patent/AU2003210217A1/en
Priority to AT03742510T priority patent/ATE428705T1/de
Publication of WO2003070721A1 publication Critical patent/WO2003070721A1/de
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Definitions

  • R 3 and R 4 together with the nitrogen atom to which they are attached can also form a five- or six-membered ring which is interrupted by an atom from the group 0, N or S and / or one or more substituents from the group Halogen, Ci-C ß- alkyl, Ci-Cg-haloalkyl or oxy-C ⁇ -C 3 alkyleneoxy can carry or in which two adjacent C atoms or one N and one adjacent beard C atom can be connected by a C 4 -C 4 alkylene chain;
  • Protic solvents such as alcohols, for example ethanol, or aprotic solvents, such as aromatic hydrocarbons or ethers, for example toluene, o-, m- and p-xylene, diethyl ether, diisopropyl ether, tert. -Butyl methyl ether, dioxane or tetrahydrofuran, especially tert. Butyl methyl ether or tetrahydrofuran, in question.
  • auxiliary bases are those mentioned below: NaHC0 3 , Na 2 C0, NaHP0 4 , NaB0, diethylaniline or ethyldiisopropylamine.
  • R 2 represents halogen, Ci-C ⁇ -alkyl or Ci-Cs-alkoxy, in particular halogen.
  • Nitroderivate such as dinitro- (1-methylheptyl) phenylcrotonate, 2-sec-butyl-4, 6-dinitrophenyl-3, 3-dimethylacrylate, 2-sec-butyl-4, 6-dinitrophenyl-isopropyl carbonate, 5- Nitro-isophthalic acid-di-isopropyl ester;
  • Heterocyclic substances such as 2-heptadecyl-2-imidazoline acetate, 2,4-dichloro ⁇ 6- (o-chloroanilino) -s-triazine, 0.0-diethyl-phthalimidophosphonothioate, 5-amino-l- [ bis- (dimethylamino) phosphinyl] -3-phenyl-l, 2, 4-triazole, 2, 3-dicyano-l, 4-di-thioanthraquinone, 2-thio-l, 3-dithiolo [4, 5 -b] quinoxaline,

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
PCT/EP2003/001162 2002-02-21 2003-02-06 2-(2-pyridyl)-5-phenyl-6-aminopyrimidine, verfahren und zwischenprodukte zu ihrer herstellung und ihre verwendung zur bekämpfung von schadpilzen Ceased WO2003070721A1 (de)

Priority Applications (6)

Application Number Priority Date Filing Date Title
US10/505,146 US7320975B2 (en) 2002-02-21 2003-02-06 2-(2-pyridyl)-5-phenyl-6-aminopyrimidine, method and intermediate products for the production and use thereof for combating noxious fungi
EP03742510A EP1504001B1 (de) 2002-02-21 2003-02-06 2-(2-pyridyl)-5-phenyl-6-aminopyrimidine, verfahren und zwischenprodukte zu ihrer herstellung und ihre verwendung zur bekämpfung von schadpilzen
JP2003569628A JP2005523286A (ja) 2002-02-21 2003-02-06 ２−（２−ピリジル）−５−フェニル−６−アミノピリミジン、それを調製するための方法及び中間生成物、並びに、有害な真菌を防除するためのそれの使用
DE50311420T DE50311420D1 (de) 2002-02-21 2003-02-06 2-(2-pyridyl)-5-phenyl-6-aminopyrimidine, verfahren und zwischenprodukte zu ihrer herstellung und ihre verwendung zur bekämpfung von schadpilzen
AU2003210217A AU2003210217A1 (en) 2002-02-21 2003-02-06 2-(2-pyridyl)-5-phenyl-6-aminopyrimidine, method and intermediate products for the production and use thereof for combating noxious fungi
AT03742510T ATE428705T1 (de) 2002-02-21 2003-02-06 2-(2-pyridyl)-5-phenyl-6-aminopyrimidine, verfahren und zwischenprodukte zu ihrer herstellung und ihre verwendung zur bekämpfung von schadpilzen

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE10207428.3 2002-02-21
DE10207428 2002-02-21
DE2002110136 DE10210136A1 (de) 2002-03-08 2002-03-08 2-(2-Pyridyl)-5-phanyl-6-aminopyrimidine, Verfahren und Zwischenprodukte zu ihrer Herstellung und ihre Verwendung zur Bekämpfung von Schadpilzen
DE10210136.1 2002-03-08

Publications (1)

Publication Number Publication Date
WO2003070721A1 true WO2003070721A1 (de) 2003-08-28

Family

ID=27758401

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2003/001162 Ceased WO2003070721A1 (de) 2002-02-21 2003-02-06 2-(2-pyridyl)-5-phenyl-6-aminopyrimidine, verfahren und zwischenprodukte zu ihrer herstellung und ihre verwendung zur bekämpfung von schadpilzen

Country Status (7)

Country Link
US (1) US7320975B2 (https=)
EP (1) EP1504001B1 (https=)
JP (1) JP2005523286A (https=)
AT (1) ATE428705T1 (https=)
AU (1) AU2003210217A1 (https=)
DE (1) DE50311420D1 (https=)
WO (1) WO2003070721A1 (https=)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006005571A1 (de) * 2004-07-14 2006-01-19 Basf Aktiengesellschaft 2-substituierte pyrimidine, verfahren zu ihrer herstellung und ihre verwendung zur bekämpfung von schadpilzen
WO2006079556A2 (en) 2005-01-31 2006-08-03 Basf Aktiengesellschaft Substituted 5-phenyl pyrimidines i in therapy
WO2008015250A1 (de) * 2006-08-02 2008-02-07 Basf Se Pyrimidinverbundungen zur bekämpfung von schadpilzen und krebs
US7524849B2 (en) 2003-09-24 2009-04-28 Wyeth Holdings Corporation 5-arylpyrimidines as anticancer agents

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0402260B1 (pt) * 2004-06-15 2015-02-18 Botica Com Farmaceutica Ltda Composição para produtos de higiene, cosméticos e perfumes.
WO2007093527A1 (de) * 2006-02-15 2007-08-23 Basf Se 2-substituierte pyrimidine und ihre verwendung als pestizide
CN101453893A (zh) * 2006-03-27 2009-06-10 巴斯夫欧洲公司 取代的5-杂芳基-4-氨基嘧啶
TWI409265B (zh) * 2008-08-20 2013-09-21 Merck Sharp & Dohme 經取代之吡啶及嘧啶衍生物及彼等於治療病毒感染之用途

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5250530A (en) * 1989-07-11 1993-10-05 Hoechst Aktiengesellschaft Aminopyrimidine derivatives, and their use as fungicides

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5250530A (en) * 1989-07-11 1993-10-05 Hoechst Aktiengesellschaft Aminopyrimidine derivatives, and their use as fungicides

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
H.-J. KABBE: "SUBSTITUIERTE 4-HYDROXY- UND 4-AMINO-PYRIMIDINE", LIEBIGS ANNALEN DER CHEMIE., vol. 704, 1967, VERLAG CHEMIE GMBH. WEINHEIM., DE, pages 144 - 9, XP002243074, ISSN: 0170-2041 *

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7524849B2 (en) 2003-09-24 2009-04-28 Wyeth Holdings Corporation 5-arylpyrimidines as anticancer agents
WO2006005571A1 (de) * 2004-07-14 2006-01-19 Basf Aktiengesellschaft 2-substituierte pyrimidine, verfahren zu ihrer herstellung und ihre verwendung zur bekämpfung von schadpilzen
WO2006079556A2 (en) 2005-01-31 2006-08-03 Basf Aktiengesellschaft Substituted 5-phenyl pyrimidines i in therapy
WO2006079556A3 (en) * 2005-01-31 2006-09-21 Basf Ag Substituted 5-phenyl pyrimidines i in therapy
EA014098B1 (ru) * 2005-01-31 2010-08-30 Басф Акциенгезелльшафт Замещённые 5-фенилпиримидины в терапии рака, фармацевтическая композиция на их основе и способ лечения рака у животных
WO2008015250A1 (de) * 2006-08-02 2008-02-07 Basf Se Pyrimidinverbundungen zur bekämpfung von schadpilzen und krebs

Also Published As

Publication number Publication date
JP2005523286A (ja) 2005-08-04
US20050107401A1 (en) 2005-05-19
EP1504001B1 (de) 2009-04-15
DE50311420D1 (de) 2009-05-28
ATE428705T1 (de) 2009-05-15
EP1504001A1 (de) 2005-02-09
US7320975B2 (en) 2008-01-22
AU2003210217A1 (en) 2003-09-09

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