WO2003018188A1 - Systeme de solvant multiphase compatible - Google Patents

Systeme de solvant multiphase compatible Download PDF

Info

Publication number
WO2003018188A1
WO2003018188A1 PCT/JP2002/008501 JP0208501W WO03018188A1 WO 2003018188 A1 WO2003018188 A1 WO 2003018188A1 JP 0208501 W JP0208501 W JP 0208501W WO 03018188 A1 WO03018188 A1 WO 03018188A1
Authority
WO
WIPO (PCT)
Prior art keywords
solvent system
mixed
organic solvents
state
compatible
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2002/008501
Other languages
English (en)
French (fr)
Inventor
Kazuhiro Chiba
Yusuke Kono
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Japan Science and Technology Agency
Original Assignee
Japan Science and Technology Agency
Japan Science and Technology Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP2001254109A external-priority patent/JP3538672B2/ja
Priority claimed from JP2001385493A external-priority patent/JP4283469B2/ja
Application filed by Japan Science and Technology Agency, Japan Science and Technology Corp filed Critical Japan Science and Technology Agency
Priority to DE60238846T priority Critical patent/DE60238846D1/de
Priority to US10/486,383 priority patent/US20040214989A1/en
Priority to EP02767852A priority patent/EP1426101B1/en
Publication of WO2003018188A1 publication Critical patent/WO2003018188A1/ja
Anticipated expiration legal-status Critical
Priority to US11/556,492 priority patent/US8344103B2/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/74—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C69/757—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B61/00—Other general methods
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/14—All rings being cycloaliphatic
    • C07C2602/26—All rings being cycloaliphatic the ring system containing ten carbon atoms
    • C07C2602/28—Hydrogenated naphthalenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Vaporization, Distillation, Condensation, Sublimation, And Cold Traps (AREA)
PCT/JP2002/008501 2001-08-24 2002-08-23 Systeme de solvant multiphase compatible Ceased WO2003018188A1 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
DE60238846T DE60238846D1 (de) 2001-08-24 2002-08-23 Verträgliches mehrphasiges organisches lösungsmittelsystem
US10/486,383 US20040214989A1 (en) 2001-08-24 2002-08-23 Compatible-multiphase organic solvent system
EP02767852A EP1426101B1 (en) 2001-08-24 2002-08-23 Compatible-multiphase organic solvent system
US11/556,492 US8344103B2 (en) 2001-08-24 2006-11-03 Compatible-multiphase organic solvent system

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2001-254109 2001-08-24
JP2001254109A JP3538672B2 (ja) 2001-08-24 2001-08-24 相溶性−多相有機溶媒システム
JP2001385493A JP4283469B2 (ja) 2001-12-19 2001-12-19 相溶性−多相有機溶媒システムによりアミノ酸を逐次的に付加する液相ペプチド合成法
JP2001-385493 2001-12-19

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US10486383 A-371-Of-International 2002-08-23
US11/556,492 Division US8344103B2 (en) 2001-08-24 2006-11-03 Compatible-multiphase organic solvent system

Publications (1)

Publication Number Publication Date
WO2003018188A1 true WO2003018188A1 (fr) 2003-03-06

Family

ID=26620919

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2002/008501 Ceased WO2003018188A1 (fr) 2001-08-24 2002-08-23 Systeme de solvant multiphase compatible

Country Status (5)

Country Link
US (2) US20040214989A1 (ja)
EP (1) EP1426101B1 (ja)
CN (1) CN1289182C (ja)
DE (1) DE60238846D1 (ja)
WO (1) WO2003018188A1 (ja)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004024315A1 (ja) * 2002-08-29 2004-03-25 Tokyo University Of Agriculture And Technology Tlo Co., Ltd. 相溶状態・分離状態が温度で可逆変化する溶媒セットをもちいた化学プロセス装置
WO2004096429A1 (ja) * 2003-05-01 2004-11-11 Tokyo University Of Agriculture And Technology Tlo Co., Ltd. 温度により相溶状態と分離状態とが可逆変化する溶媒セットにおいて定温度で相溶・分離をおこなう方法ならびに装置
WO2007122847A1 (ja) * 2006-03-24 2007-11-01 National University Corporation, Tokyo University Of Agriculture And Technology 有機合成用試薬、及び当該試薬を用いた有機合成反応方法
WO2009014177A1 (ja) * 2007-07-25 2009-01-29 Ajinomoto Co., Inc. ジベンゾフルベン誘導体の淘汰方法
WO2012029794A1 (ja) 2010-08-30 2012-03-08 味の素株式会社 分岐鎖含有芳香族化合物
WO2012165546A1 (ja) * 2011-05-31 2012-12-06 味の素株式会社 ペプチドの製造方法
US11420997B2 (en) 2018-04-13 2022-08-23 Jitsubo Co., Ltd. Peptide synthesis method
US12351601B2 (en) 2019-04-25 2025-07-08 Ajinomoto Co., Inc. Method for producing peptide continuously

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1927584T3 (en) * 2005-09-20 2017-02-20 Jitsubo Co Ltd CARRIER FOR SEPARATION, PROCEDURE FOR SEPARATION OF CONNECTION AND PROCEDURE FOR SYNTHESIS OF PEPTIDE USING THE CARRIER
WO2016140232A1 (ja) 2015-03-04 2016-09-09 Jitsubo株式会社 ペプチド合成方法
EP4079737B1 (en) 2015-12-21 2026-02-11 Texas Tech University System System and method for solution phase gap peptide synthesis
WO2019009317A1 (ja) * 2017-07-05 2019-01-10 日産化学株式会社 ベンジル化合物
CN110317130B (zh) * 2018-03-29 2021-12-21 深圳翰宇药业股份有限公司 化合物及其制备方法和应用
US12024537B2 (en) 2018-05-31 2024-07-02 Sederma Compositions and methods for chemical synthesis
EP3917937A4 (en) 2019-02-01 2022-11-23 Sederma SYNTHETIC STRATEGY FOR A SPLIT PROTECTION GROUP
WO2023106356A1 (ja) * 2021-12-08 2023-06-15 富士フイルム株式会社 ペプチド化合物の製造方法、保護基形成用試薬、及び置換ベンジル化合物

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6461497A (en) * 1987-08-31 1989-03-08 Central Glass Co Ltd Mixed solvent

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816175A (en) * 1988-04-25 1989-03-28 Allied-Signal Inc. Azeotrope-like compositions of dichlorotrifluoroethane, methanol, cyclopentane and nitromethane
US5039444A (en) * 1989-12-14 1991-08-13 Allied-Signal Inc. Azeotrope-like compositions of dichloro-trifluoroethane, cyclopentane and optionally nitromethane
US5064558A (en) * 1990-06-25 1991-11-12 Allied-Signal Inc. Azeotrope-like compositions of 1,1,2-tri-chloro-1,2,2-trifluoroethane, 1,2-dichloroethylene, cyclopentane, methanol, nitromethane and optionally diisopropylamine

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6461497A (en) * 1987-08-31 1989-03-08 Central Glass Co Ltd Mixed solvent

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BERGBREITER ET AL., J. AM. CHEM. SOC., vol. 122, 2000, pages 9058 - 9064
BIANCHINI ET AL., ORGANOMETALLICS, vol. 14, 1995, pages 5458 - 5459
See also references of EP1426101A4 *

Cited By (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004024315A1 (ja) * 2002-08-29 2004-03-25 Tokyo University Of Agriculture And Technology Tlo Co., Ltd. 相溶状態・分離状態が温度で可逆変化する溶媒セットをもちいた化学プロセス装置
WO2004096429A1 (ja) * 2003-05-01 2004-11-11 Tokyo University Of Agriculture And Technology Tlo Co., Ltd. 温度により相溶状態と分離状態とが可逆変化する溶媒セットにおいて定温度で相溶・分離をおこなう方法ならびに装置
JPWO2004096429A1 (ja) * 2003-05-01 2006-07-13 農工大ティー・エル・オー株式会社 温度により相溶状態と分離状態とが可逆変化する溶媒セットにおいて定温度で相溶・分離をおこなう方法ならびに装置
JP4576561B2 (ja) * 2003-05-01 2010-11-10 農工大ティー・エル・オー株式会社 温度により相溶状態と分離状態とが可逆変化する溶媒セットにおいて定温度で相溶・分離をおこなう方法ならびに装置
US8293948B2 (en) 2006-03-24 2012-10-23 Jitsubo Co., Ltd. Reagent for organic synthesis and method of organic synthesis reaction with the reagent
WO2007122847A1 (ja) * 2006-03-24 2007-11-01 National University Corporation, Tokyo University Of Agriculture And Technology 有機合成用試薬、及び当該試薬を用いた有機合成反応方法
US8093435B2 (en) 2006-03-24 2012-01-10 Jitsubo Co., Ltd. Reagent for organic synthesis and method of organic synthesis reaction with the reagent
WO2009014177A1 (ja) * 2007-07-25 2009-01-29 Ajinomoto Co., Inc. ジベンゾフルベン誘導体の淘汰方法
WO2012029794A1 (ja) 2010-08-30 2012-03-08 味の素株式会社 分岐鎖含有芳香族化合物
US8546534B2 (en) 2010-08-30 2013-10-01 Ajinomoto Co., Inc. Branched chain-containing aromatic compound
JP5929756B2 (ja) * 2010-08-30 2016-06-08 味の素株式会社 分岐鎖含有芳香族化合物
US9499579B2 (en) 2010-08-30 2016-11-22 Ajinomoto Co., Inc. Branched chain-containing aromatic compound
US10711033B2 (en) 2010-08-30 2020-07-14 Ajinomoto Co., Inc. Branched chain-containing aromatic compound
WO2012165546A1 (ja) * 2011-05-31 2012-12-06 味の素株式会社 ペプチドの製造方法
JPWO2012165546A1 (ja) * 2011-05-31 2015-02-23 味の素株式会社 ペプチドの製造方法
US9353147B2 (en) 2011-05-31 2016-05-31 Ajinomoto Co., Inc. Method for producing peptide
JP2017036322A (ja) * 2011-05-31 2017-02-16 味の素株式会社 ペプチドの製造方法
US11420997B2 (en) 2018-04-13 2022-08-23 Jitsubo Co., Ltd. Peptide synthesis method
US12351601B2 (en) 2019-04-25 2025-07-08 Ajinomoto Co., Inc. Method for producing peptide continuously

Also Published As

Publication number Publication date
US20070066799A1 (en) 2007-03-22
US8344103B2 (en) 2013-01-01
US20040214989A1 (en) 2004-10-28
CN1289182C (zh) 2006-12-13
EP1426101B1 (en) 2011-01-05
CN1575199A (zh) 2005-02-02
EP1426101A1 (en) 2004-06-09
DE60238846D1 (de) 2011-02-17
EP1426101A4 (en) 2006-11-15

Similar Documents

Publication Publication Date Title
CA2304662A1 (en) Methods for fabricating polymer-based controlled release preparations
EP1127570A3 (en) Production process for polymeric micelle composition charged therein with drug
CA2367020A1 (en) Method for producing solid dosage forms containing cyclodextrin
EP1072652A3 (de) Beschichtungsmittel
WO2004032905A8 (en) Gabapentin tablets and methods for their preparation
EP1348432A4 (en) CYCLODEXTRIN-CONTAINING PHARMACEUTICAL COMPOSITION
EP0984020A3 (en) Azithromycin monohydrate isopropanol clathrate and methods for the manufacture thereof.
CA2435276A1 (en) Syntactic deformable foam compositions and methods for making
WO2007120756A3 (en) Nanoparticles, methods of making, and applications using same
CA2265686A1 (en) A crystalline substance of cefditoren pivoxyl and the production of the same
WO2005003086A3 (de) Sulfonsäurederivate polycyclischer farbstoffe für analytische anwendungen
WO1999047536A3 (de) Verfahren zur synthese von nucleinsäuremolekülen
EP1538174A3 (en) Process for the purification of polyarylene sulfide
EP1300363A3 (en) Method for producing fullerenes
WO2002030870A3 (de) Substituierte c-cyclohexylmethylamin-derivate
MY126071A (en) Crystalline form ii of cabergoline.
WO2000071553A8 (en) Novel aluminosiloxane compound and process for preparing the same
WO2002026742A3 (en) PROCESS FOR THE PREPARATION OF 2-ALKOXY-6-TRIFLUOROMETHYL-N-([1,2,4]TRIAZOLO[1,5-c]PYRIMIDIN-2-YL)BENZENESULFONAMIDES
AU2002354492A1 (en) Organic ntc composition, organic ntc element, and process for producing the same
AU2001238131A1 (en) Polymer compositions useful as dye complexing agents, and processes for preparing same
CA2369255A1 (en) An improved process for the preparation of non-hygroscopic azithromycin dihydrate
WO2002048074A1 (en) Method for producing molecular compound
AU2002352013A1 (en) Method for the continuous production of n-methyl-2-pyrrolidone (nmp)
EP1028143A4 (en) METAL / ORGANIC POLYMER COMPOSITE STRUCTURE CONTAINING ULTRAFINE METAL PARTICLES, ARRANGED IN A ROW, AND METHOD FOR THE PRODUCTION THEREOF
KR950026374A (ko) 과립상의 껌 제조방법

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): CN US

Kind code of ref document: A1

Designated state(s): CN

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FR GB GR IE IT LU MC NL PT SE SK TR

Kind code of ref document: A1

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LU MC NL PT SE SK TR

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
WWE Wipo information: entry into national phase

Ref document number: 10486383

Country of ref document: US

WWE Wipo information: entry into national phase

Ref document number: 2002767852

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 2002820915X

Country of ref document: CN

WWP Wipo information: published in national office

Ref document number: 2002767852

Country of ref document: EP