WO2002080663A1 - Animaux d'experimentation destines a l'evaluation d'effets therapeutiques sur des lesions epitheliales de la cornee - Google Patents

Animaux d'experimentation destines a l'evaluation d'effets therapeutiques sur des lesions epitheliales de la cornee Download PDF

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Publication number
WO2002080663A1
WO2002080663A1 PCT/JP2002/000007 JP0200007W WO02080663A1 WO 2002080663 A1 WO2002080663 A1 WO 2002080663A1 JP 0200007 W JP0200007 W JP 0200007W WO 02080663 A1 WO02080663 A1 WO 02080663A1
Authority
WO
WIPO (PCT)
Prior art keywords
corneal epithelial
therapeutic effects
evaluation
drugs
model animals
Prior art date
Application number
PCT/JP2002/000007
Other languages
English (en)
French (fr)
Inventor
Iwao Katsuyama
Original Assignee
Biochemical And Pharmacological Laboratories Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biochemical And Pharmacological Laboratories Inc. filed Critical Biochemical And Pharmacological Laboratories Inc.
Priority to CA002441638A priority Critical patent/CA2441638A1/en
Priority to KR1020037012816A priority patent/KR100542785B1/ko
Priority to EP02759840A priority patent/EP1380205A4/en
Publication of WO2002080663A1 publication Critical patent/WO2002080663A1/ja

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/107—Rabbit
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/30—Bird
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Environmental Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Animal Husbandry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Eye Examination Apparatus (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
PCT/JP2002/000007 2001-03-30 2002-01-04 Animaux d'experimentation destines a l'evaluation d'effets therapeutiques sur des lesions epitheliales de la cornee WO2002080663A1 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CA002441638A CA2441638A1 (en) 2001-03-30 2002-01-04 Experimental animals for evaluation of therapeutic effects on corneal epithelial damages
KR1020037012816A KR100542785B1 (ko) 2001-03-30 2002-01-04 각막 상피 장해 모델 동물 및 그 모델 동물을 이용한 약제의 평가방법 및 그 평가방법을 이용하여 선택된 약제
EP02759840A EP1380205A4 (en) 2001-03-30 2002-01-04 EXPERIMENTAL ANIMALS FOR THE EVALUATION OF THERAPEUTIC EFFECTS ON EPITHELIAL LESIONS OF THE CORNEA

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP2001101250 2001-03-30
JP2001-101250 2001-03-30
JP2001226460 2001-07-26
JP2001-226460 2001-07-26
JP2001-363147 2001-11-28
JP2001363147A JP3945625B2 (ja) 2001-03-30 2001-11-28 角膜上皮障害モデル動物及びそのモデル動物を用いた薬剤の評価方法並びにその評価方法を用いて選択された薬剤

Publications (1)

Publication Number Publication Date
WO2002080663A1 true WO2002080663A1 (fr) 2002-10-17

Family

ID=27346428

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2002/000007 WO2002080663A1 (fr) 2001-03-30 2002-01-04 Animaux d'experimentation destines a l'evaluation d'effets therapeutiques sur des lesions epitheliales de la cornee

Country Status (7)

Country Link
US (1) US6924413B2 (ja)
EP (1) EP1380205A4 (ja)
JP (1) JP3945625B2 (ja)
KR (1) KR100542785B1 (ja)
CA (1) CA2441638A1 (ja)
TW (1) TWI287974B (ja)
WO (1) WO2002080663A1 (ja)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5487498B2 (ja) * 2009-09-18 2014-05-07 国立大学法人山口大学 角膜又は結膜における点状染色状態の評価方法
RU2564912C2 (ru) * 2009-11-27 2015-10-10 Р-Тек Уено, Лтд. Способ скрининга агента, пригодного для лечения синдрома сухого глаза и/или поражения роговицы и конъюнктивы, фармацевтическая композиция, полученная с помощью этого способа
KR101199750B1 (ko) 2010-06-22 2012-11-08 중앙대학교 산학협력단 장기간 건성안 토끼 동물모델 및 이를 이용한 건성안 예방 또는 치료용 약물 스크리닝 방법
RU2480845C1 (ru) * 2012-02-27 2013-04-27 Государственное бюджетное учреждение "Уфимский научно-исследовательский институт глазных болезней Академии наук Республики Башкортостан" Способ моделирования бактериального кератита
KR101948156B1 (ko) 2013-12-10 2019-02-14 인제대학교 산학협력단 알칼리 화상을 이용한 각막 혼탁증 동물모델 및 각막 혼탁증 예방 또는 치료용 약학조성물
US10022218B2 (en) 2014-02-14 2018-07-17 Cook Medical Technologies Llc Tricuspid regurgitation model and methods of evaluating intraluminal medical devices
RU2709834C1 (ru) * 2019-05-14 2019-12-23 Федеральное государственное бюджетное военное образовательное учреждение высшего образования "Военно-медицинская академия имени С.М. Кирова" Министерства обороны Российской Федерации (ВМедА) Способ моделирования в эксперименте рецидивирующей эрозии роговицы

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09124505A (ja) 1995-10-31 1997-05-13 Samu Kenkyusho:Kk 角膜障害治療・予防剤
JP3059092B2 (ja) 1995-11-15 2000-07-04 田辺製薬株式会社 ドライアイおよびドライアイを原因とする疾患の予防・治療剤
US5900407A (en) * 1997-02-06 1999-05-04 Inspire Pharmaceuticals, Inc. Method of treating dry eye disease with uridine triphosphates and related compounds

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
ANDREWS P.M. ET AL., CORNEA, vol. 13, no. 3, 1994, pages 253 - 258, XP002950717 *
FUJIHARA T. ET AL., J. OCULAR PHARMACOL., vol. 11, no. 4, 1995, pages 503 - 508, XP002950714 *
RUBERTI J.W. ET AL., INVEST. OPHTHALMOL. VIS. SCI., vol. 41, 2000, pages 2523 - 2530, XP002950715 *
See also references of EP1380205A4 *
UNO T. ET AL., IVOS, vol. 42, no. 4, 2001, pages S263 + S263A, XP002950716 *

Also Published As

Publication number Publication date
JP2003102331A (ja) 2003-04-08
US20030041339A1 (en) 2003-02-27
KR20030087039A (ko) 2003-11-12
JP3945625B2 (ja) 2007-07-18
EP1380205A1 (en) 2004-01-14
TWI287974B (en) 2007-10-11
KR100542785B1 (ko) 2006-01-11
CA2441638A1 (en) 2002-10-17
US6924413B2 (en) 2005-08-02
EP1380205A4 (en) 2004-05-26

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