WO2002080663A1 - Animaux d'experimentation destines a l'evaluation d'effets therapeutiques sur des lesions epitheliales de la cornee - Google Patents
Animaux d'experimentation destines a l'evaluation d'effets therapeutiques sur des lesions epitheliales de la cornee Download PDFInfo
- Publication number
- WO2002080663A1 WO2002080663A1 PCT/JP2002/000007 JP0200007W WO02080663A1 WO 2002080663 A1 WO2002080663 A1 WO 2002080663A1 JP 0200007 W JP0200007 W JP 0200007W WO 02080663 A1 WO02080663 A1 WO 02080663A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- corneal epithelial
- therapeutic effects
- evaluation
- drugs
- model animals
- Prior art date
Links
- 230000008378 epithelial damage Effects 0.000 title abstract 4
- 238000011156 evaluation Methods 0.000 title abstract 3
- 230000001225 therapeutic effect Effects 0.000 title abstract 2
- 238000010171 animal model Methods 0.000 title 1
- 241001465754 Metazoa Species 0.000 abstract 4
- 239000003814 drug Substances 0.000 abstract 4
- 229940079593 drug Drugs 0.000 abstract 4
- 238000000034 method Methods 0.000 abstract 2
- 230000002745 absorbent Effects 0.000 abstract 1
- 239000002250 absorbent Substances 0.000 abstract 1
- 210000002919 epithelial cell Anatomy 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 230000003204 osmotic effect Effects 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/107—Rabbit
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/30—Bird
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Environmental Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Zoology (AREA)
- Animal Husbandry (AREA)
- Biodiversity & Conservation Biology (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Ophthalmology & Optometry (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Eye Examination Apparatus (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002441638A CA2441638A1 (en) | 2001-03-30 | 2002-01-04 | Experimental animals for evaluation of therapeutic effects on corneal epithelial damages |
KR1020037012816A KR100542785B1 (ko) | 2001-03-30 | 2002-01-04 | 각막 상피 장해 모델 동물 및 그 모델 동물을 이용한 약제의 평가방법 및 그 평가방법을 이용하여 선택된 약제 |
EP02759840A EP1380205A4 (en) | 2001-03-30 | 2002-01-04 | EXPERIMENTAL ANIMALS FOR THE EVALUATION OF THERAPEUTIC EFFECTS ON EPITHELIAL LESIONS OF THE CORNEA |
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2001101250 | 2001-03-30 | ||
JP2001-101250 | 2001-03-30 | ||
JP2001226460 | 2001-07-26 | ||
JP2001-226460 | 2001-07-26 | ||
JP2001-363147 | 2001-11-28 | ||
JP2001363147A JP3945625B2 (ja) | 2001-03-30 | 2001-11-28 | 角膜上皮障害モデル動物及びそのモデル動物を用いた薬剤の評価方法並びにその評価方法を用いて選択された薬剤 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2002080663A1 true WO2002080663A1 (fr) | 2002-10-17 |
Family
ID=27346428
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2002/000007 WO2002080663A1 (fr) | 2001-03-30 | 2002-01-04 | Animaux d'experimentation destines a l'evaluation d'effets therapeutiques sur des lesions epitheliales de la cornee |
Country Status (7)
Country | Link |
---|---|
US (1) | US6924413B2 (ja) |
EP (1) | EP1380205A4 (ja) |
JP (1) | JP3945625B2 (ja) |
KR (1) | KR100542785B1 (ja) |
CA (1) | CA2441638A1 (ja) |
TW (1) | TWI287974B (ja) |
WO (1) | WO2002080663A1 (ja) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5487498B2 (ja) * | 2009-09-18 | 2014-05-07 | 国立大学法人山口大学 | 角膜又は結膜における点状染色状態の評価方法 |
RU2564912C2 (ru) * | 2009-11-27 | 2015-10-10 | Р-Тек Уено, Лтд. | Способ скрининга агента, пригодного для лечения синдрома сухого глаза и/или поражения роговицы и конъюнктивы, фармацевтическая композиция, полученная с помощью этого способа |
KR101199750B1 (ko) | 2010-06-22 | 2012-11-08 | 중앙대학교 산학협력단 | 장기간 건성안 토끼 동물모델 및 이를 이용한 건성안 예방 또는 치료용 약물 스크리닝 방법 |
RU2480845C1 (ru) * | 2012-02-27 | 2013-04-27 | Государственное бюджетное учреждение "Уфимский научно-исследовательский институт глазных болезней Академии наук Республики Башкортостан" | Способ моделирования бактериального кератита |
KR101948156B1 (ko) | 2013-12-10 | 2019-02-14 | 인제대학교 산학협력단 | 알칼리 화상을 이용한 각막 혼탁증 동물모델 및 각막 혼탁증 예방 또는 치료용 약학조성물 |
US10022218B2 (en) | 2014-02-14 | 2018-07-17 | Cook Medical Technologies Llc | Tricuspid regurgitation model and methods of evaluating intraluminal medical devices |
RU2709834C1 (ru) * | 2019-05-14 | 2019-12-23 | Федеральное государственное бюджетное военное образовательное учреждение высшего образования "Военно-медицинская академия имени С.М. Кирова" Министерства обороны Российской Федерации (ВМедА) | Способ моделирования в эксперименте рецидивирующей эрозии роговицы |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH09124505A (ja) | 1995-10-31 | 1997-05-13 | Samu Kenkyusho:Kk | 角膜障害治療・予防剤 |
JP3059092B2 (ja) | 1995-11-15 | 2000-07-04 | 田辺製薬株式会社 | ドライアイおよびドライアイを原因とする疾患の予防・治療剤 |
US5900407A (en) * | 1997-02-06 | 1999-05-04 | Inspire Pharmaceuticals, Inc. | Method of treating dry eye disease with uridine triphosphates and related compounds |
-
2001
- 2001-11-28 JP JP2001363147A patent/JP3945625B2/ja not_active Expired - Fee Related
- 2001-12-31 TW TW090133501A patent/TWI287974B/zh not_active IP Right Cessation
-
2002
- 2002-01-04 EP EP02759840A patent/EP1380205A4/en not_active Withdrawn
- 2002-01-04 CA CA002441638A patent/CA2441638A1/en not_active Abandoned
- 2002-01-04 KR KR1020037012816A patent/KR100542785B1/ko not_active IP Right Cessation
- 2002-01-04 WO PCT/JP2002/000007 patent/WO2002080663A1/ja active Application Filing
- 2002-01-10 US US10/043,366 patent/US6924413B2/en not_active Expired - Fee Related
Non-Patent Citations (5)
Title |
---|
ANDREWS P.M. ET AL., CORNEA, vol. 13, no. 3, 1994, pages 253 - 258, XP002950717 * |
FUJIHARA T. ET AL., J. OCULAR PHARMACOL., vol. 11, no. 4, 1995, pages 503 - 508, XP002950714 * |
RUBERTI J.W. ET AL., INVEST. OPHTHALMOL. VIS. SCI., vol. 41, 2000, pages 2523 - 2530, XP002950715 * |
See also references of EP1380205A4 * |
UNO T. ET AL., IVOS, vol. 42, no. 4, 2001, pages S263 + S263A, XP002950716 * |
Also Published As
Publication number | Publication date |
---|---|
JP2003102331A (ja) | 2003-04-08 |
US20030041339A1 (en) | 2003-02-27 |
KR20030087039A (ko) | 2003-11-12 |
JP3945625B2 (ja) | 2007-07-18 |
EP1380205A1 (en) | 2004-01-14 |
TWI287974B (en) | 2007-10-11 |
KR100542785B1 (ko) | 2006-01-11 |
CA2441638A1 (en) | 2002-10-17 |
US6924413B2 (en) | 2005-08-02 |
EP1380205A4 (en) | 2004-05-26 |
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