WO2001000804A3 - Genes corynebacterium glutamicum codant des proteines de stress, resistance et tolerance - Google Patents

Genes corynebacterium glutamicum codant des proteines de stress, resistance et tolerance Download PDF

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Publication number
WO2001000804A3
WO2001000804A3 PCT/IB2000/000922 IB0000922W WO0100804A3 WO 2001000804 A3 WO2001000804 A3 WO 2001000804A3 IB 0000922 W IB0000922 W IB 0000922W WO 0100804 A3 WO0100804 A3 WO 0100804A3
Authority
WO
WIPO (PCT)
Prior art keywords
srt
proteins
nucleic acid
acid molecules
corynebacterium glutamicum
Prior art date
Application number
PCT/IB2000/000922
Other languages
English (en)
Other versions
WO2001000804A2 (fr
Inventor
Markus Pompejus
Burkhard Kroeger
Hartwig Schroeder
Oskar Zelder
Gregor Haberhauer
Heung-Shick Lee
Hyung-Joon Kim
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to JP2001506798A priority Critical patent/JP2003525593A/ja
Priority to MXPA01012844A priority patent/MXPA01012844A/es
Priority to EP00944135A priority patent/EP1290178A2/fr
Priority to HU0203340A priority patent/HUP0203340A2/hu
Priority to CA002380870A priority patent/CA2380870A1/fr
Priority to KR1020017016588A priority patent/KR100834986B1/ko
Application filed by Basf Ag filed Critical Basf Ag
Priority to SK1888-2001A priority patent/SK18882001A3/sk
Priority to AU58369/00A priority patent/AU783703B2/en
Priority to ES00944135T priority patent/ES2184658T1/es
Publication of WO2001000804A2 publication Critical patent/WO2001000804A2/fr
Publication of WO2001000804A3 publication Critical patent/WO2001000804A3/fr
Priority to AU2006200801A priority patent/AU2006200801A1/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/34—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

L'invention porte sur des molécules d'acide nucléique isolées, appelées molécules d'acide nucléique SRT qui codent de nouvelles protéines SRT issues de Corynebacterium glutamicum. L'invention porte également sur des molécules d'acide nucléique antisens, sur des vecteurs d'expression de recombinaison contenant les molécules d'acide nucléique SRT, et sur des cellules hôtes dans lesquelles les vecteurs d'expression ont été introduits. L'invention porte encore sur des protéines SRT isolées, des protéines SRT mutées, des protéines de fusion, des peptides antigéniques et sur des procédés visant à accroître la production d'un composé désiré issu de C. glutamicum par manipulation des gènes SRT dans cet organisme.
PCT/IB2000/000922 1999-06-25 2000-06-23 Genes corynebacterium glutamicum codant des proteines de stress, resistance et tolerance WO2001000804A2 (fr)

Priority Applications (10)

Application Number Priority Date Filing Date Title
MXPA01012844A MXPA01012844A (es) 1999-06-25 2000-06-23 Genes de corynebacterium glutamicum que codifican proteinas de tolerancia y resistencia al estres.
EP00944135A EP1290178A2 (fr) 1999-06-25 2000-06-23 Genes corynebacterium glutamicum codant des proteines de stress, resistance et tolerance
HU0203340A HUP0203340A2 (hu) 1999-06-25 2000-06-23 Stressz-, rezisztencia- és toleranciafehérjéket kódoló Corynebacterium glutamicum gének
CA002380870A CA2380870A1 (fr) 1999-06-25 2000-06-23 Genes corynebacterium glutamicum codant des proteines de stress, resistance et tolerance
KR1020017016588A KR100834986B1 (ko) 1999-06-25 2000-06-23 스트레스 저항성 및 내성 단백질을 코딩하는코리네박테리움 글루타미쿰 유전자
JP2001506798A JP2003525593A (ja) 1999-06-25 2000-06-23 コリネバクテリウム−グルタミカム遺伝子をコードするストレス、耐性および寛容性タンパク質
SK1888-2001A SK18882001A3 (sk) 1999-06-25 2000-06-23 Gény Corynebacterium glutamicum kódujúce stresové, rezistenčné a tolerančné proteíny
AU58369/00A AU783703B2 (en) 1999-06-25 2000-06-23 Corynebacterium glutamicum genes encoding stress, resistance and tolerance proteins
ES00944135T ES2184658T1 (es) 1999-06-25 2000-06-23 Genes de corynebacterium glutamicum que codifican proteinas de esfuerzo, resistencia y tolerancia.
AU2006200801A AU2006200801A1 (en) 1999-06-25 2006-02-24 Corynebacterium glutamicum genes encoding stress, resistance and tolerance proteins

Applications Claiming Priority (24)

Application Number Priority Date Filing Date Title
US14103199P 1999-06-25 1999-06-25
US60/141,031 1999-06-25
US14269299P 1999-07-01 1999-07-01
DE19930429.7 1999-07-01
DE19930429 1999-07-01
US60/142,692 1999-07-01
DE19931457.8 1999-07-08
DE19931457 1999-07-08
DE19931413 1999-07-08
DE19931541 1999-07-08
DE19931541.8 1999-07-08
DE19931413.6 1999-07-08
DE19932230.9 1999-07-09
DE19932230 1999-07-09
DE19932209.0 1999-07-09
DE19932209 1999-07-09
DE19932914 1999-07-14
DE19932914.1 1999-07-14
US15121499P 1999-08-27 1999-08-27
US60/151,214 1999-08-27
DE19940764 1999-08-27
DE19940764.9 1999-08-27
DE19941382 1999-08-31
DE19941382.7 1999-08-31

Publications (2)

Publication Number Publication Date
WO2001000804A2 WO2001000804A2 (fr) 2001-01-04
WO2001000804A3 true WO2001000804A3 (fr) 2001-08-02

Family

ID=27582954

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2000/000922 WO2001000804A2 (fr) 1999-06-25 2000-06-23 Genes corynebacterium glutamicum codant des proteines de stress, resistance et tolerance

Country Status (12)

Country Link
EP (1) EP1290178A2 (fr)
JP (3) JP2003525593A (fr)
KR (4) KR100834986B1 (fr)
AU (1) AU783703B2 (fr)
CA (1) CA2380870A1 (fr)
ES (1) ES2184658T1 (fr)
HU (1) HUP0203340A2 (fr)
MX (1) MXPA01012844A (fr)
PL (1) PL359863A1 (fr)
SK (1) SK18882001A3 (fr)
TR (1) TR200103709T2 (fr)
WO (1) WO2001000804A2 (fr)

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CN1298854C (zh) 1999-07-02 2007-02-07 味之素株式会社 编码蔗糖pts酶ⅱ的dna
US6569650B1 (en) 1999-08-13 2003-05-27 Degussa Ag Process for the fermentative preparation of metabolic products and for the nucleotide sequences encoding for the sod gene
EP1156115A1 (fr) 2000-05-12 2001-11-21 Degussa AG Souche de Corynebacterium glutamicum ayant une activité de sécrétion améliorée
DE10032350A1 (de) 2000-07-04 2002-01-24 Degussa Neue für das mdhA-Gen kodierende Nukleotidsequenzen
ATE274061T1 (de) 2000-08-10 2004-09-15 Degussa Nukleotid sequenzen kodierend für das lysr2 gen
DE10042051A1 (de) 2000-08-26 2002-03-07 Degussa Neue für das cstA-Gen kodierende Nukleotidsequenzen
WO2002018589A2 (fr) * 2000-09-02 2002-03-07 Degussa Ag Sequences nucleotidiques codant le gene sigc
EP1315815B1 (fr) 2000-09-09 2007-04-18 Degussa GmbH Sequences nucleotidiques codant pour le gene dep34
US6759224B2 (en) 2000-09-09 2004-07-06 Degussa Ag Nucleotide sequences which code for the sahH gene
AU2001293723A1 (en) 2000-09-09 2002-03-22 Degussa A.G. Nucleotide sequences coding for the dep33 gene
DE10154181A1 (de) * 2001-11-05 2003-05-15 Basf Ag Gene die für Stressresistenz-und Toleranz-Proteine codieren
DE10154180A1 (de) * 2001-11-05 2003-05-15 Basf Ag gene die für genetische Stabilitäts-, genexpressions-und Faltungsproteine codieren
WO2005014828A2 (fr) * 2003-08-01 2005-02-17 Basf Plant Science Gmbh Procede de production de composes chimiques fins
US8008545B2 (en) 2003-04-15 2011-08-30 Basf Plant Science Gmbh Process for the production of fine chemicals
US7468262B2 (en) 2003-05-16 2008-12-23 Ajinomoto Co., Inc. Polynucleotides encoding useful polypeptides in corynebacterium glutamicum ssp. lactofermentum
US8728795B2 (en) 2003-12-18 2014-05-20 Basf Se Pgro expression units
DE10359594A1 (de) 2003-12-18 2005-07-28 Basf Ag PEF-TU-Expressionseinheiten
DE10359660A1 (de) * 2003-12-18 2005-07-28 Basf Ag Psod-Expressionseinheiten
DE102004035065A1 (de) 2004-07-20 2006-02-16 Basf Ag P-ET-TS-Expressionseinheiten
JP5537818B2 (ja) * 2008-03-04 2014-07-02 国立大学法人信州大学 有用物質の製造方法
US20120034669A1 (en) * 2009-02-18 2012-02-09 Kyowa Hakko Bio Co., Ltd. Process for producing useful substance
KR101694850B1 (ko) * 2014-10-08 2017-01-10 씨제이제일제당 주식회사 L-글루타민을 생산하는 미생물 및 이를 이용한 l-글루타민 생산방법
KR101941745B1 (ko) * 2016-07-20 2019-01-24 씨제이제일제당 (주) 아실전이효소의 활성을 갖는 미생물 및 이의 용도
EP3456833A1 (fr) 2017-09-18 2019-03-20 Evonik Degussa GmbH Méthode de production d'acides aminés l par fermentation
EP3467099A1 (fr) 2017-10-05 2019-04-10 Evonik Degussa GmbH Procédé de production d'acides aminés l par fermentation
RU2019128538A (ru) 2018-09-26 2021-03-11 Эвоник Оперейшенс ГмбХ Способ ферментативного получения l-лизина
CN111088202B (zh) * 2019-12-25 2022-01-04 南京工业大学 一种通过生物成膜连续化发酵生产赖氨酸的重组谷氨酸棒杆菌及其构建方法
CN111909912B (zh) * 2020-09-11 2022-03-08 四川农业大学 一种提升水稻穗期高温耐受性的map3k-19基因及其编码得到的蛋白和应用
WO2023165952A1 (fr) * 2022-03-01 2023-09-07 Evonik Operations Gmbh Production biotechnologique de protéines de collagène et de protéines de type collagène bactérien par des micro-organismes recombinants

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Publication number Priority date Publication date Assignee Title
EP0252558A2 (fr) * 1986-07-04 1988-01-13 SCLAVO S.p.A. Elément d'ADN de corynebacterium diphtériae ayant les propriétés spécifiques d'un élément d'insertion IS
FR2607827A2 (fr) * 1985-09-27 1988-06-10 Pasteur Institut Fragment d'adn comprenant au moins une partie d'un gene de resistance aux lincosamides et applications biochimiques et biologiques
WO1988009819A2 (fr) * 1987-06-12 1988-12-15 Massachusetts Institute Of Technology Passage biosynthetique pour threonine de c. glutamicum
EP0752472A1 (fr) * 1994-02-24 1997-01-08 Ajinomoto Co., Inc. Nouveau gene tire de corynebacterium et son utilisation
WO1999002692A1 (fr) * 1997-07-09 1999-01-21 Ajinomoto Co., Inc. Genes dtsr sensibles a la temperature

Patent Citations (6)

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FR2607827A2 (fr) * 1985-09-27 1988-06-10 Pasteur Institut Fragment d'adn comprenant au moins une partie d'un gene de resistance aux lincosamides et applications biochimiques et biologiques
EP0252558A2 (fr) * 1986-07-04 1988-01-13 SCLAVO S.p.A. Elément d'ADN de corynebacterium diphtériae ayant les propriétés spécifiques d'un élément d'insertion IS
WO1988009819A2 (fr) * 1987-06-12 1988-12-15 Massachusetts Institute Of Technology Passage biosynthetique pour threonine de c. glutamicum
EP0752472A1 (fr) * 1994-02-24 1997-01-08 Ajinomoto Co., Inc. Nouveau gene tire de corynebacterium et son utilisation
WO1999002692A1 (fr) * 1997-07-09 1999-01-21 Ajinomoto Co., Inc. Genes dtsr sensibles a la temperature
EP1002866A1 (fr) * 1997-07-09 2000-05-24 Ajinomoto Co., Inc. Genes dtsr sensibles a la temperature

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PETER H ET AL: "CORYNEBACTERIUM GLUTAMICUM IS EQUIPPED WITH FOUR SECONDARY CARRIERSFOR COMPATIBLE SOLUTES: IDENTIFICATION, SEQUENCING, AND CHARACTERIZATION OF THE PROLINE/ECTOINE UPTAKE SYSTEM, PROP, AND THE ECTOINE/PROLINE/GLYCINE BETAINE CARRIER, ECTP", JOURNAL OF BACTERIOLOGY,WASHINGTON, DC,US, vol. 180, no. 22, 1998, pages 6005 - 6012, XP000917352, ISSN: 0021-9193 *
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Also Published As

Publication number Publication date
CA2380870A1 (fr) 2001-01-04
AU5836900A (en) 2001-01-31
EP1290178A2 (fr) 2003-03-12
HUP0203340A2 (hu) 2003-01-28
KR20070087095A (ko) 2007-08-27
KR20070087094A (ko) 2007-08-27
AU783703B2 (en) 2005-11-24
TR200103709T2 (tr) 2002-08-21
PL359863A1 (en) 2004-09-06
KR20060118631A (ko) 2006-11-23
ES2184658T1 (es) 2003-04-16
KR20030000013A (ko) 2003-01-03
MXPA01012844A (es) 2002-07-09
SK18882001A3 (sk) 2002-09-10
WO2001000804A2 (fr) 2001-01-04
KR100878335B1 (ko) 2009-01-14
KR100834986B1 (ko) 2008-06-03
JP2007244391A (ja) 2007-09-27
JP2007244392A (ja) 2007-09-27
JP2003525593A (ja) 2003-09-02

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