WO2000071747A3 - Erkennungssystem zur auftrennung von probenbestandteilen, seine herstellung und verwendung - Google Patents

Erkennungssystem zur auftrennung von probenbestandteilen, seine herstellung und verwendung Download PDF

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Publication number
WO2000071747A3
WO2000071747A3 PCT/EP2000/002938 EP0002938W WO0071747A3 WO 2000071747 A3 WO2000071747 A3 WO 2000071747A3 EP 0002938 W EP0002938 W EP 0002938W WO 0071747 A3 WO0071747 A3 WO 0071747A3
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WO
WIPO (PCT)
Prior art keywords
sample
detection system
component
bonded
region
Prior art date
Application number
PCT/EP2000/002938
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English (en)
French (fr)
Other versions
WO2000071747A2 (de
Inventor
Dirk Boekenkamp
Hans-Ulrich Hoppe
Petra Burgstaller
Original Assignee
Aventis Res & Tech Gmbh & Co
Dirk Boekenkamp
Hoppe Hans Ulrich
Petra Burgstaller
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Res & Tech Gmbh & Co, Dirk Boekenkamp, Hoppe Hans Ulrich, Petra Burgstaller filed Critical Aventis Res & Tech Gmbh & Co
Priority to AU36591/00A priority Critical patent/AU3659100A/en
Publication of WO2000071747A2 publication Critical patent/WO2000071747A2/de
Publication of WO2000071747A3 publication Critical patent/WO2000071747A3/de

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Die Erfindung bezieht sich auf ein Erkennungssystem enthaltend (a) einen Träger (Komponente (a)) und (b) mindestens eine an den Träger gebundene Erkennungseinheit (Komponente (b)), vorzugsweise eine Nukleinsäure, wobei die genannte Erkennungseinheit (Komponente (b)) eine Region (A) mit einer definierten Struktur und eine zu der Region (A) benachbarte Region (B) mit einer randomisierten Struktur enthält, auf ein Verfahren zur Auftrennung einzelner Bestandteile in einer Probe, bei dem an mindestens eine an einen Träger gebundene Erkennungseinheit (Komponente (b)) unter geeigneten Bedingungen mindestens ein Bestandteil der Probe gebunden wird, und auf die Verwendung des erfindungsgemässen Erkennungssystems und des erfindungsgemässen Verfahrens zum Auffinden und/oder zur Identifizierung bzw. Charakterisierung von Nukleinsäuren und/oder Proteinen einer Probe bzw. zum Auffinden und/oder zur Identifizierung von zellulären oder künstlichen Bindepartnern.
PCT/EP2000/002938 1999-05-25 2000-04-01 Erkennungssystem zur auftrennung von probenbestandteilen, seine herstellung und verwendung WO2000071747A2 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU36591/00A AU3659100A (en) 1999-05-25 2000-04-01 Detection system for separating constituents of a sample and production and use of the same

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19923966A DE19923966C2 (de) 1999-05-25 1999-05-25 Erkennungssystem zur Auftrennung von Probenbestandteilen, seine Herstellung und Verwendung
DE19923966.5 1999-05-25

Publications (2)

Publication Number Publication Date
WO2000071747A2 WO2000071747A2 (de) 2000-11-30
WO2000071747A3 true WO2000071747A3 (de) 2001-06-14

Family

ID=7909147

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/EP2000/002938 WO2000071747A2 (de) 1999-05-25 2000-04-01 Erkennungssystem zur auftrennung von probenbestandteilen, seine herstellung und verwendung
PCT/EP2000/004791 WO2000071749A2 (de) 1999-05-25 2000-05-25 Erkennungssystem zur untersuchung von molekülwechselwirkungen, seine herstellung und verwendung

Family Applications After (1)

Application Number Title Priority Date Filing Date
PCT/EP2000/004791 WO2000071749A2 (de) 1999-05-25 2000-05-25 Erkennungssystem zur untersuchung von molekülwechselwirkungen, seine herstellung und verwendung

Country Status (10)

Country Link
EP (1) EP1185704A2 (de)
JP (1) JP2003500066A (de)
CN (1) CN1413262A (de)
AU (2) AU3659100A (de)
CA (1) CA2374438A1 (de)
CZ (1) CZ20014210A3 (de)
DE (1) DE19923966C2 (de)
EE (1) EE200100616A (de)
IL (1) IL146371A0 (de)
WO (2) WO2000071747A2 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4107500A (en) * 1999-03-22 2000-10-09 Paul Cullen Nucleic acid combination
US20040161741A1 (en) * 2001-06-30 2004-08-19 Elazar Rabani Novel compositions and processes for analyte detection, quantification and amplification
JP2003299489A (ja) * 2002-02-08 2003-10-21 Mitsubishi Chemicals Corp 核酸構築物
EP1650562A4 (de) * 2003-07-31 2006-08-30 Genefield Inc Verfahren zum screening von nützlichem protein

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993017126A1 (en) * 1992-02-19 1993-09-02 The Public Health Research Institute Of The City Of New York, Inc. Novel oligonucleotide arrays and their use for sorting, isolating, sequencing, and manipulating nucleic acids
WO1997027317A1 (en) * 1996-01-23 1997-07-31 Affymetrix, Inc. Nucleic acid analysis techniques
WO1997031256A2 (en) * 1996-02-09 1997-08-28 Cornell Research Foundation, Inc. Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays
WO1998031700A1 (en) * 1997-01-21 1998-07-23 The General Hospital Corporation Selection of proteins using rna-protein fusions
US5795714A (en) * 1992-11-06 1998-08-18 Trustees Of Boston University Method for replicating an array of nucleic acid probes
US5849486A (en) * 1993-11-01 1998-12-15 Nanogen, Inc. Methods for hybridization analysis utilizing electrically controlled hybridization
DE19741716A1 (de) * 1997-09-22 1999-03-25 Hoechst Ag Adressierbares modulares Erkennungssystem, seine Herstellung und Verwendung
WO1999023492A1 (en) * 1997-10-31 1999-05-14 Sarnoff Corporation Method for enhancing fluorescence
WO1999051773A1 (en) * 1998-04-03 1999-10-14 Phylos, Inc. Addressable protein arrays
WO2001016352A1 (en) * 1999-08-27 2001-03-08 Phylos, Inc. Methods for encoding and sorting in vitro translated proteins

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5700637A (en) * 1988-05-03 1997-12-23 Isis Innovation Limited Apparatus and method for analyzing polynucleotide sequences and method of generating oligonucleotide arrays

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993017126A1 (en) * 1992-02-19 1993-09-02 The Public Health Research Institute Of The City Of New York, Inc. Novel oligonucleotide arrays and their use for sorting, isolating, sequencing, and manipulating nucleic acids
US5795714A (en) * 1992-11-06 1998-08-18 Trustees Of Boston University Method for replicating an array of nucleic acid probes
US5849486A (en) * 1993-11-01 1998-12-15 Nanogen, Inc. Methods for hybridization analysis utilizing electrically controlled hybridization
WO1997027317A1 (en) * 1996-01-23 1997-07-31 Affymetrix, Inc. Nucleic acid analysis techniques
WO1997031256A2 (en) * 1996-02-09 1997-08-28 Cornell Research Foundation, Inc. Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays
WO1998031700A1 (en) * 1997-01-21 1998-07-23 The General Hospital Corporation Selection of proteins using rna-protein fusions
DE19741716A1 (de) * 1997-09-22 1999-03-25 Hoechst Ag Adressierbares modulares Erkennungssystem, seine Herstellung und Verwendung
WO1999023492A1 (en) * 1997-10-31 1999-05-14 Sarnoff Corporation Method for enhancing fluorescence
WO1999051773A1 (en) * 1998-04-03 1999-10-14 Phylos, Inc. Addressable protein arrays
WO2001016352A1 (en) * 1999-08-27 2001-03-08 Phylos, Inc. Methods for encoding and sorting in vitro translated proteins

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NIEMEYER C M ET AL: "OLIGONUCLEOTIDE-DIRECTED SELF-ASSEMBLY OF PROTEINS: SEMISYNTHETIC DNA-STREPTAVIDIN HYBRID MOLECULES AS CONNECTORS FOR THE GENERATION OF MACROSCOPIC ARRAYS AND THE CONSTRUCTION OF SUPRAMOLECULAR BIOCONJUGATES", NUCLEIC ACIDS RESEARCH,GB,OXFORD UNIVERSITY PRESS, SURREY, vol. 22, no. 25, 1994, pages 5530 - 5539, XP000645135, ISSN: 0305-1048 *

Also Published As

Publication number Publication date
CZ20014210A3 (cs) 2002-06-12
DE19923966C2 (de) 2003-04-24
WO2000071747A2 (de) 2000-11-30
JP2003500066A (ja) 2003-01-07
AU3659100A (en) 2000-12-12
CN1413262A (zh) 2003-04-23
AU5676000A (en) 2000-12-12
EE200100616A (et) 2003-02-17
WO2000071749A2 (de) 2000-11-30
DE19923966A1 (de) 2000-11-30
IL146371A0 (en) 2002-07-25
CA2374438A1 (en) 2000-11-30
WO2000071749A3 (de) 2001-09-07
EP1185704A2 (de) 2002-03-13

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