ATE292282T1 - Verfahren zur zellseparation unter verwendung von immunorosetten - Google Patents

Verfahren zur zellseparation unter verwendung von immunorosetten

Info

Publication number
ATE292282T1
ATE292282T1 AT00930932T AT00930932T ATE292282T1 AT E292282 T1 ATE292282 T1 AT E292282T1 AT 00930932 T AT00930932 T AT 00930932T AT 00930932 T AT00930932 T AT 00930932T AT E292282 T1 ATE292282 T1 AT E292282T1
Authority
AT
Austria
Prior art keywords
cells
immunorosets
cell separation
immunorosettes
red blood
Prior art date
Application number
AT00930932T
Other languages
English (en)
Inventor
Terry E Thomas
Carrie Peters
Peter Lansdorp
Original Assignee
Stemcell Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stemcell Technologies Inc filed Critical Stemcell Technologies Inc
Application granted granted Critical
Publication of ATE292282T1 publication Critical patent/ATE292282T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/80Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood groups or blood types or red blood cells
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5094Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for blood cell populations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31Immunoglobulins specific features characterized by aspects of specificity or valency multispecific

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Ecology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT00930932T 1999-05-28 2000-05-26 Verfahren zur zellseparation unter verwendung von immunorosetten ATE292282T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US13677099P 1999-05-28 1999-05-28
US19337100P 2000-03-31 2000-03-31
US20347700P 2000-05-11 2000-05-11
PCT/CA2000/000616 WO2000073794A2 (en) 1999-05-28 2000-05-26 Method for separating cells using immunorosettes

Publications (1)

Publication Number Publication Date
ATE292282T1 true ATE292282T1 (de) 2005-04-15

Family

ID=27384918

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00930932T ATE292282T1 (de) 1999-05-28 2000-05-26 Verfahren zur zellseparation unter verwendung von immunorosetten

Country Status (11)

Country Link
US (2) US6448075B1 (de)
EP (1) EP1185867B1 (de)
JP (1) JP4526749B2 (de)
CN (1) CN1218182C (de)
AT (1) ATE292282T1 (de)
AU (1) AU769903B2 (de)
CA (1) CA2375115C (de)
DE (1) DE60019111T2 (de)
HK (1) HK1044819B (de)
IL (2) IL146660A0 (de)
WO (1) WO2000073794A2 (de)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7135335B2 (en) * 1999-05-28 2006-11-14 Stemcell Technologies Inc. Method for separating cells using immunorosettes
US20030157060A1 (en) * 2000-04-03 2003-08-21 Bell David N Production of tcr gamma delta t cells
US7205157B2 (en) * 2001-01-08 2007-04-17 Becton, Dickinson And Company Method of separating cells from a sample
DE60238801D1 (de) * 2001-04-10 2011-02-10 Bioe Llc Zelltrennungszusammensetzungen und -verfahren
US6667022B2 (en) * 2001-08-14 2003-12-23 General Electric Co. Process for separating synthesis gas into fuel cell quality hydrogen and sequestration ready carbon dioxide
CA2499826C (en) * 2002-09-27 2015-03-24 Bioe, Inc. Cell separation compositions and methods
EP1574583A1 (de) * 2004-03-10 2005-09-14 Roche Diagnostics GmbH Verfahren zur Isolierung von Bakterien aus biologischen Proben
EP1574584B1 (de) * 2004-03-10 2006-11-15 Boehringer Mannheim Gmbh Verfahren zur Isolierung von Bakterien aus biologischen Proben
US7622108B2 (en) * 2004-04-23 2009-11-24 Bioe, Inc. Multi-lineage progenitor cells
CA2563518C (en) * 2004-04-23 2014-09-02 Bioe, Inc. Multi-lineage progenitor cells
US8263404B2 (en) * 2005-04-08 2012-09-11 Medical Discovery Partners Llc Method for enriching rare cell subpopulations from blood
CA2640185A1 (en) * 2006-01-24 2007-08-02 Christopher J. Centeno Mesenchymal stem cell isolation and transplantation method and system to be used in a clinical setting
US7727763B2 (en) * 2006-04-17 2010-06-01 Bioe, Llc Differentiation of multi-lineage progenitor cells to respiratory epithelial cells
KR100833793B1 (ko) * 2006-05-16 2008-05-29 세원셀론텍(주) 골수 유래 골 생성용 유핵 세포 분리 방법
US7862813B2 (en) * 2006-07-29 2011-01-04 Bjork Jr Robert Lamar Bi-specific monoclonal antibody (specific for both CD3 and CD11b) therapeutic drug
US7713688B2 (en) * 2007-01-26 2010-05-11 Bioe, Llc Methods and compositions for depleting specific cell populations from blood tissues
US8574567B2 (en) * 2007-05-03 2013-11-05 The Brigham And Women's Hospital, Inc. Multipotent stem cells and uses thereof
WO2008137115A1 (en) 2007-05-03 2008-11-13 The Brigham And Women's Hospital, Inc. Multipotent stem cells and uses thereof
US9095562B2 (en) 2007-07-05 2015-08-04 Regenerative Sciences, Inc. Methods and compositions for optimized expansion and implantation of mesenchymal stem cells
EP2192908A4 (de) * 2007-07-25 2010-09-01 Bioe Inc Differenzierung von vorläuferzellen mehrerer abstammung gegenüber chondrozyten
US20110200642A1 (en) * 2007-12-19 2011-08-18 Regenerative Sciences, Llc Compositions and Methods to Promote Implantation and Engrafment of Stem Cells
US20110052533A1 (en) * 2008-03-14 2011-03-03 Regenerative Sciences, Llc Compositions and Methods for Cartilage Repair
CA2724839A1 (en) * 2008-05-21 2009-11-26 Bioe Llc Differentiation of multi-lineage progenitor cells to pancreatic cells
JP2012510874A (ja) 2008-12-05 2012-05-17 リジェネレイティブ サイエンシーズ, エルエルシー 無血管組織の修復を促進するための方法及び組成物
US20100168022A1 (en) * 2008-12-11 2010-07-01 Centeno Christopher J Use of In-Vitro Culture to Design or Test Personalized Treatment Regimens
JP5660035B2 (ja) * 2009-04-28 2015-01-28 コニカミノルタ株式会社 融合タンパク質含有集合体、その製造方法及び該集合体を用いたアッセイ法
US20110054929A1 (en) * 2009-09-01 2011-03-03 Cell Solutions Colorado Llc Stem Cell Marketplace
US9113950B2 (en) 2009-11-04 2015-08-25 Regenerative Sciences, Llc Therapeutic delivery device
BR112012018166A2 (pt) 2010-01-21 2015-09-15 Biocep Ltd separação magnética de células raras.
FR2963108B1 (fr) * 2010-07-21 2017-06-23 Diagast Procede magnetique d'immunodiagnostic et kit pour la mise en evidence de complexe anticorps/antigene de groupe/phenotype sanguin
WO2012018930A1 (en) * 2010-08-03 2012-02-09 University Of Miami Methods of isolating and expanding human t regulatory cells and uses thereof for cellular therapy
US9850296B2 (en) 2010-08-10 2017-12-26 Ecole Polytechnique Federale De Lausanne (Epfl) Erythrocyte-binding therapeutics
EP2652499B1 (de) * 2010-12-15 2019-08-07 Cytosed, Inc. Antikörpergebundenes immunsedimentationsmittel und verfahren zur isolierung eines ziels aus einer probe damit
US9133438B2 (en) 2011-06-29 2015-09-15 Biorestorative Therapies, Inc. Brown fat cell compositions and methods
ES2602500T3 (es) 2011-11-25 2017-02-21 Miltenyi Biotec Gmbh Método de separación celular
DE102012003700B3 (de) * 2012-02-28 2012-11-29 FLACOD GmbH Verfahren zur Trennung von Verbänden maligner Zellen und Verbänden aus Stromazellen einer Malignomgewebeprobe
US8921055B2 (en) 2012-10-30 2014-12-30 Berkeley Lights, Inc. Detecting cells secreting a protein of interest
EP2970906B1 (de) 2013-03-15 2019-08-21 Stemcell Technologies Inc. Verfahren zur zellseparation unter verwendung von immunorosetten und magnetischen teilchen
US11221325B2 (en) 2013-09-30 2022-01-11 Sekisui Medical Co., Ltd. Device for concentration and separation of circulating tumor cells, and method for concentration and separation of circulating tumor cells
CA2936914C (en) 2014-01-21 2020-08-18 Stemcell Technologies Inc. Method for separating target entities from a sample using a composition of mono-specific tetrameric antibody complexes coupled to a surface
CN106687584B (zh) * 2014-09-04 2021-08-13 干细胞技术公司 用于t细胞或nk细胞活化和扩增的可溶性抗体复合物
GB201418382D0 (en) * 2014-10-16 2014-12-03 Ge Healthcare Uk Ltd Device and method for separating cells
EP3037170A1 (de) 2014-12-27 2016-06-29 Miltenyi Biotec GmbH Multisort-Zelltrennverfahren
WO2016122014A1 (ko) * 2015-01-27 2016-08-04 한국생명공학연구원 자연살해세포의 대량생산 방법 및 상기 방법으로 수득된 자연살해세포의 항암제로서의 용도
US12398371B2 (en) 2015-01-27 2025-08-26 Korea Research Institute Of Bioscience Method for mass producing natural killer cell and use of natural killer cell obtained by the method as anti-cancer agent
US10983114B2 (en) 2015-06-10 2021-04-20 Stemcell Technologies Inc. Method for the in situ formation of bifunctional immunological complexes
JP6779483B2 (ja) 2016-09-29 2020-11-04 住友ゴム工業株式会社 医療用検査装置及び細胞検査方法
WO2018170335A1 (en) * 2017-03-15 2018-09-20 Orca Biosystems Inc. Compositions and methods for hematopoietic stem cell transplants
JP7109719B2 (ja) * 2018-02-14 2022-08-01 住友ゴム工業株式会社 特定細胞捕捉方法
WO2019215590A1 (en) * 2018-05-07 2019-11-14 Anokion Sa Glycophorin a antigen-binding proteins
CN112469816A (zh) * 2018-06-06 2021-03-09 加拿大干细胞技术公司 用于富集髓系来源的抑制细胞的试剂盒、组合物和方法
US11614440B2 (en) 2019-01-24 2023-03-28 Sumitomo Rubber Industries, Ltd. Specific cell fractionating and capturing methods
US11725042B2 (en) 2019-06-27 2023-08-15 Stemcell Technologies Canada Inc. Methods and devices for complexing target entities
US12486492B2 (en) 2020-03-05 2025-12-02 Korea Research Institute Of Bioscience Method for producing memory-like NK cells with ability to express higher levels of NCRs, cytotoxicity, and IFN-γ than NK cells in human peripheral blood

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8501219A (nl) * 1985-04-29 1986-11-17 Stichting Vrienden Van De Stic Immunologisch complex, de bereiding en toepassing daarvan.
LU86752A1 (fr) * 1987-01-30 1988-08-23 Univ Bruxelles Procede de production d'anticorps monoclonaux humains(igg)anticytomegalovirus et anticorps monoclonaux ainsi obtenus
US5086002A (en) * 1987-09-07 1992-02-04 Agen Biomedical, Ltd. Erythrocyte agglutination assay
AU8869291A (en) * 1990-10-04 1992-04-28 University Of Virginia Alumni Patents Foundation, The Primate erythrocyte bound monoclonal antibody heteropolymers
US5374531A (en) * 1993-03-22 1994-12-20 Zynaxis, Inc. Immunoassay for determination of cells
JP3331398B2 (ja) * 1993-05-28 2002-10-07 バクスター、インターナショナル、インコーポレイテッド 不均質な細胞混合物から特定の細胞集団を分離するための方法、装置およびシステム
US6306575B1 (en) * 1995-06-16 2001-10-23 Stemcell Technologies, Inc. Methods for preparing enriched human hematopoietic cell preparations
US6117985A (en) * 1995-06-16 2000-09-12 Stemcell Technologies Inc. Antibody compositions for preparing enriched cell preparations
US5877299A (en) * 1995-06-16 1999-03-02 Stemcell Technologies Inc. Methods for preparing enriched human hematopoietic cell preparations
DE19710496A1 (de) * 1997-03-13 1998-09-17 Boehringer Mannheim Gmbh Verfahren zum Nachweis antigenspezifischer T-Zellen nach Anreicherung von mononukleären Zellpopulationen
US6572856B1 (en) * 1998-09-10 2003-06-03 The University Of Virginia Patent Foundation Methods for the prevention and treatment of cancer using anti-C3b(i) antibodies

Also Published As

Publication number Publication date
US6448075B1 (en) 2002-09-10
JP2003501629A (ja) 2003-01-14
CN1367876A (zh) 2002-09-04
EP1185867A2 (de) 2002-03-13
US20030092078A1 (en) 2003-05-15
CA2375115A1 (en) 2000-12-07
DE60019111T2 (de) 2006-01-26
CN1218182C (zh) 2005-09-07
AU4905900A (en) 2000-12-18
HK1044819A1 (en) 2002-11-01
HK1044819B (en) 2005-07-29
WO2000073794A3 (en) 2001-08-30
EP1185867B1 (de) 2005-03-30
IL146660A (en) 2007-10-31
JP4526749B2 (ja) 2010-08-18
WO2000073794A2 (en) 2000-12-07
IL146660A0 (en) 2002-07-25
DE60019111D1 (de) 2005-05-04
CA2375115C (en) 2011-05-24
AU769903B2 (en) 2004-02-05
US6872567B2 (en) 2005-03-29

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