DE60238801D1 - Zelltrennungszusammensetzungen und -verfahren - Google Patents

Zelltrennungszusammensetzungen und -verfahren

Info

Publication number
DE60238801D1
DE60238801D1 DE60238801T DE60238801T DE60238801D1 DE 60238801 D1 DE60238801 D1 DE 60238801D1 DE 60238801 T DE60238801 T DE 60238801T DE 60238801 T DE60238801 T DE 60238801T DE 60238801 D1 DE60238801 D1 DE 60238801D1
Authority
DE
Germany
Prior art keywords
methods
cell separation
separation compositions
compositions
reagents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60238801T
Other languages
English (en)
Inventor
Daniel P Collins
David M Shaut
Joel H Hapke
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bioe LLC
Original Assignee
Bioe LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioe LLC filed Critical Bioe LLC
Application granted granted Critical
Publication of DE60238801D1 publication Critical patent/DE60238801D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0081—Purging biological preparations of unwanted cells
    • C12N5/0087—Purging against subsets of blood cells, e.g. purging alloreactive T cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5094—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for blood cell populations
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • G01N33/539—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody involving precipitating reagent, e.g. ammonium sulfate
    • G01N33/541—Double or second antibody, i.e. precipitating antibody
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/101666—Particle count or volume standard or control [e.g., platelet count standards, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/107497—Preparation composition [e.g., lysing or precipitation, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
DE60238801T 2001-04-10 2002-03-07 Zelltrennungszusammensetzungen und -verfahren Expired - Lifetime DE60238801D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28282301P 2001-04-10 2001-04-10

Publications (1)

Publication Number Publication Date
DE60238801D1 true DE60238801D1 (de) 2011-02-10

Family

ID=23083276

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60238801T Expired - Lifetime DE60238801D1 (de) 2001-04-10 2002-03-07 Zelltrennungszusammensetzungen und -verfahren

Country Status (12)

Country Link
US (2) US7160723B2 (de)
EP (2) EP1377353A4 (de)
JP (2) JP4212898B2 (de)
CN (1) CN1327927C (de)
AT (1) ATE493186T1 (de)
AU (1) AU2002255678B2 (de)
CA (1) CA2442577C (de)
DE (1) DE60238801D1 (de)
IL (2) IL158171A0 (de)
MX (1) MXPA03009258A (de)
RU (1) RU2292555C2 (de)
WO (1) WO2002083262A1 (de)

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EP1639099B1 (de) 2003-06-27 2011-05-18 Université Laval Verfahren zur isolierung von zellen aus der nabelschnur
US7622108B2 (en) * 2004-04-23 2009-11-24 Bioe, Inc. Multi-lineage progenitor cells
DE602005027557D1 (de) * 2004-04-23 2011-06-01 Bioe Llc Mehrfachlinien-vorläuferzellen
WO2007121443A2 (en) * 2006-04-17 2007-10-25 Bioe, Inc. Differentiation of multi-lineage progenitor cells to respiratory epithelial cells
US7598089B2 (en) * 2006-04-19 2009-10-06 Bioe, Inc. Methods and compositions for separating cells
MX2008014110A (es) * 2006-05-02 2008-11-14 Therakos Inc Metodos y reactivos para detectar la susceptibilidad a la enfermedad del injerto versus el hospedero o mortalidad relacionada con el transplante.
US7713688B2 (en) * 2007-01-26 2010-05-11 Bioe, Llc Methods and compositions for depleting specific cell populations from blood tissues
WO2008097155A1 (en) * 2007-02-08 2008-08-14 Ge Healthcare Bio-Sciences Ab Media and method for cell separation
WO2008153802A1 (en) * 2007-05-29 2008-12-18 Eusa Pharma, Inc. Ex-vivo treatment of cancer using psma and antibodies thereto
JP5210551B2 (ja) * 2007-06-19 2013-06-12 ベックマン コールター バイオメディカル リミテッド 赤血球標識用磁性粒子
US20090029463A1 (en) * 2007-07-25 2009-01-29 Bioe, Inc. Differentiation of Multi-Lineage Progenitor Cells to Chondrocytes
EP2191849B1 (de) * 2007-09-26 2018-08-01 National Cerebral and Cardiovascular Center Wirkstoff zur suppression von in vivo auftretenden krankheitserregern
EP2294187A2 (de) * 2008-05-21 2011-03-16 BioE LLC Differenzierung von mehrlinien-vorläuferzellen zu pankreaszellen
EP2321646A1 (de) * 2008-08-04 2011-05-18 Synmed Research GmbH Verfahren zur charakterisierung, insbesondere quantifizierung, von durch, aus dem gewebe in die blutbahn rezirkulierten, blutmakrophagen intrazellulär aus gewebe aufgenommenen molekularen markern sowie analyseanordnung zur durchführung des verfahrens
CN101885770B (zh) * 2009-05-12 2014-07-30 成都生物制品研究所有限责任公司 一种特异性结合cd15的全人源抗体及应用
US9517257B2 (en) 2010-08-10 2016-12-13 Ecole Polytechnique Federale De Lausanne (Epfl) Erythrocyte-binding therapeutics
US9850296B2 (en) 2010-08-10 2017-12-26 Ecole Polytechnique Federale De Lausanne (Epfl) Erythrocyte-binding therapeutics
CA2807942C (en) * 2010-08-10 2021-07-27 Ecole Polytechnique Federale De Lausanne Erythrocyte-binding therapeutics
WO2012061291A2 (en) * 2010-11-01 2012-05-10 Bioe Llc Methods and compositions for cell separation of blood tissues
JP2013546002A (ja) * 2010-12-15 2013-12-26 サイトセッド， インコーポレイテッド 抗体連結型免疫沈降剤およびそれを使用してサンプルから標的を単離する方法
CN102839152A (zh) * 2011-06-20 2012-12-26 中国科学院上海生命科学研究院 一种快速高效获得抗原特异性b细胞的方法
DK2597153T3 (en) * 2011-11-25 2016-12-05 Miltenyi Biotec Gmbh Method for cell separation
BR112016016740B1 (pt) * 2014-01-21 2024-02-20 Stemcell Technologies Inc Método de separação de entidades alvo de uma amostra que compreende entidades alvo e entidades não alvo
US10953101B2 (en) 2014-02-21 2021-03-23 École Polytechnique Fédérale De Lausanne (Epfl) Glycotargeting therapeutics
SG10202010936RA (en) 2014-02-21 2020-12-30 Ecole Polytecnique Fed De Lausanne Epfl Epfl Tto Glycotargeting therapeutics
US10946079B2 (en) 2014-02-21 2021-03-16 Ecole Polytechnique Federale De Lausanne Glycotargeting therapeutics
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Also Published As

Publication number Publication date
CA2442577A1 (en) 2002-10-24
EP1916297B1 (de) 2010-12-29
EP1377353A1 (de) 2004-01-07
CN1327927C (zh) 2007-07-25
CA2442577C (en) 2011-08-30
EP1916297A2 (de) 2008-04-30
IL158171A (en) 2012-09-24
US7476547B2 (en) 2009-01-13
US7160723B2 (en) 2007-01-09
JP2008289506A (ja) 2008-12-04
ATE493186T1 (de) 2011-01-15
US20070154961A1 (en) 2007-07-05
JP4212898B2 (ja) 2009-01-21
JP2004526452A (ja) 2004-09-02
AU2002255678B2 (en) 2008-05-08
MXPA03009258A (es) 2004-11-12
EP1916297A3 (de) 2008-05-14
CN1658940A (zh) 2005-08-24
EP1377353A4 (de) 2005-08-31
IL158171A0 (en) 2004-03-28
RU2003132547A (ru) 2005-03-10
US20030027233A1 (en) 2003-02-06
WO2002083262A1 (en) 2002-10-24
RU2292555C2 (ru) 2007-01-27

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