WO2000067687A1 - Dispositif permettant de traiter le glaucome - Google Patents

Dispositif permettant de traiter le glaucome Download PDF

Info

Publication number
WO2000067687A1
WO2000067687A1 PCT/EP2000/004094 EP0004094W WO0067687A1 WO 2000067687 A1 WO2000067687 A1 WO 2000067687A1 EP 0004094 W EP0004094 W EP 0004094W WO 0067687 A1 WO0067687 A1 WO 0067687A1
Authority
WO
WIPO (PCT)
Prior art keywords
laser catheter
light
fiber
catheter according
fiber arrangement
Prior art date
Application number
PCT/EP2000/004094
Other languages
German (de)
English (en)
Inventor
Johannes Junger
Eduard Haefliger
Original Assignee
Glautec Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glautec Ag filed Critical Glautec Ag
Priority to EP00938627A priority Critical patent/EP1107715A1/fr
Priority to AU53934/00A priority patent/AU5393400A/en
Publication of WO2000067687A1 publication Critical patent/WO2000067687A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/00781—Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/008—Methods or devices for eye surgery using laser
    • A61F9/00802—Methods or devices for eye surgery using laser for photoablation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • A61B18/22—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor
    • A61B18/26—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor for producing a shock wave, e.g. laser lithotripsy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • A61B18/22—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor
    • A61B2018/2205—Characteristics of fibres
    • A61B2018/2211—Plurality of fibres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • A61B18/22—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor
    • A61B2018/2255—Optical elements at the distal end of probe tips
    • A61B2018/2288—Optical elements at the distal end of probe tips the optical fibre cable having a curved distal end
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/008—Methods or devices for eye surgery using laser
    • A61F2009/00861—Methods or devices for eye surgery using laser adapted for treatment at a particular location
    • A61F2009/00868—Ciliary muscles or trabecular meshwork
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/008—Methods or devices for eye surgery using laser
    • A61F2009/00885—Methods or devices for eye surgery using laser for treating a particular disease
    • A61F2009/00891—Glaucoma

Definitions

  • the invention relates to a laser catheter for glaucoma treatment with a light-guiding fiber arrangement, at the proximal end of which light can be coupled into the fiber and at the distal end of which a light exit surface is provided, from which the light emerges from the fiber.
  • the sponge-like trabecular mechanism through which the aqueous humor flows from the anterior and posterior eye chambers, is preferably removed locally with UV light, which is generated by means of an excimer laser and guided into the interior of the eye via light guides, so that the aqueous humor in the Schlemm'schen is easier Can pass through which it is ultimately discharged.
  • UV light from an excimer laser with the aid of optical fibers in order to perforate the trabecular mill on site by local tissue ablation.
  • Previously known laser catheters have at their distal light exit end a light exit surface cut perpendicular to the fiber axis, through which the light leaves the laser catheter in the longitudinal direction of the fiber on the distal side.
  • the conventional laser catheters prove to be disadvantageous, especially since their distal end cannot be brought into close proximity or in direct contact with the tissue of the trabecular mechanism to be perforated, since this is located in the tapering chamber angle.
  • 1 shows an image of a section of an eye chamber angle, which is included as an acute angle from the cornea H at the transition to the dermis L and the iris R at the transition to the ciliary body Z.
  • the trabecular mechanism T located in the angular range must be perforated with suitably designed laser catheters.
  • the invention has for its object to form a laser catheter for glaucoma treatment with a light-guiding fiber arrangement, at the proximal end of which light can be coupled into the fiber and at its distal end a light exit surface is provided from which the light emerges from the fiber in such a way that the Carrying out a glaucoma treatment can be carried out reliably and effectively.
  • the solution to the problem on which the invention is based is specified in claim 1.
  • a laser catheter for glaucoma treatment with a light-guiding fiber arrangement at the proximal end of which light can be coupled into the fiber and at the distal end of which a light exit surface is provided, from which the light emerges from the fiber, is designed in such a way that the light exit surface faces the longitudinal axis of the fiber arrangement encloses an angle of approximately between 30 ° and 70 ⁇ , preferably 37 s .
  • the laser catheter designed according to the invention has a beveled light exit surface, the angle of inclination of which is adapted to the chamber angle within the eye relative to the longitudinal axis of the fiber. In this way, it is possible to guide the laser catheter in close proximity or in direct contact with the trabecular mechanism in order to carry out targeted light application into the interior of the trabecular mesh tissue with suitable positioning.
  • the bevel according to the invention makes it possible for a surgeon to pass the distal tip of the laser catheter through the trabecular mechanism during the light application, all the way to the Schlemm's canal, the outer wall of which can also be perforated under certain circumstances, as a result of which the aqueous humor located in the interior of the chamber can flow through the perforation channels into the Schlemm'sche channel easier.
  • the design according to the invention of the distal tip of the fiber arrangement makes it possible, in particular, for the tissue to be ablated to lie over the entire surface in the chamber angle region on the light exit surface, as a result of which there is direct optical coupling between the glass fiber and the tissue. If the light exit surface did not lie directly on the tissue area to be ablated, the aqueous humor present in the ventricular angle would cause considerable absorption, which would significantly impair the success of the treatment.
  • the slanted light exit surface also offers the operator greater ease of use, especially since the fiber arrangement can be handled directly and in a straight line through the front chamber.
  • the surgeon maintains an almost unrestricted overview of the tissue area to be treated within the chamber angle, even during the treatment of the chamber angle, since the fiber arrangement only covers that tissue area for optical observation that is separated from the light exit surface for reasons of local light deposition and a related tissue ablation is contacted.
  • the fiber arrangement is composed as a monofiber or from a bundle of individual fibers and, at least at its distal region, has support material which radially surrounds the fiber arrangement.
  • the support material which is preferably made of biocompatible plastic or metal, serves on the one hand to increase the longitudinal stability of the fiber arrangement in order in this way to permit straight-line catheter guidance, but is also provided at the distal end of the fiber arrangement for reasons of increased break resistance.
  • the support material which, for example, is made of stainless steel and surrounds the fiber arrangement, in particular gives the surgeon safe positioning of the fiber arrangement due to the increased longitudinal rigidity.
  • the support material surrounds the fiber assembly and ends flush on the distal side at the edge region of the light exit surface in such a way that the direct contactability described above between light exit surface and tissue region remains unaffected within the chamber angle.
  • Typical size arrangements for fiber diameters are between 50 and 400 ⁇ m for fiber arrangements that consist of only one mono fiber, fiber arrangements that consist of a bundle of a large number of individual fibers are each composed of individual fibers with diameters between 1 and 100 ⁇ m.
  • the support material increases the entire fiber diameter only slightly.
  • Typical wall thicknesses of the support material are between 100 and 500 ⁇ m.
  • the fiber arrangement is selected from a light-transparent material that is able to transmit UV light with wavelengths between 150 nm to 300 nm with as little loss as possible, and is able to transmit infrared light with wavelengths greater than 1 ⁇ m.
  • the distal tip is designed to be straight or curved.
  • the laser catheter is preferably brought into the eye across the anterior chamber in order to ablate the trabecular mechanism in front of Schlemm's canal, including its inner wall.
  • the distal end of the laser catheter can also be curved, typically with angles of curvature between 6 and 10 mm, in order to minimize the risk of contact between the corneal endothelium and the lens.
  • the fiber arrangement of the laser catheter should preferably be designed such that a partial area of the fiber arrangement can be used for image transmission. This presupposes that the fiber arrangement is composed of a large number of individual fibers, of which a partial fiber bundle can be used for optical image transmission. In this way, the material removal and also the positioning of the distal end of the laser catheter can be monitored and controlled on site and corrected accordingly by the surgeon.
  • the distal end of the laser catheter can preferably have a plurality of light exit surfaces which are separate from one another and via which light can be emitted into the tissue to be treated at different application sites.
  • through-channels can be created at different points in the trabecular mechanism without repositioning the optical fiber and moving it inside the eye. This also protects the eye from traumatic tissue irritation caused by a Repositioning of the laser catheter would be connected.
  • the light application to the different light exit surfaces can either be serial or parallel. This is done either by moving a light source relative to the fiber input or by moving the fiber input relative to the light to be coupled.
  • the laser catheter designed according to the invention is particularly suitable for the integration of a miniaturized endoscope device in which an additionally provided suction or rinsing channel is provided. In this way it is possible to immediately pass the ablated tissue material extracorporeally through the corresponding channel.
  • a corresponding rinsing channel also serves for a clear field of vision, which is particularly necessary when the tissue removal is monitored visually.
  • a feed unit which moves the light catheter distally in controlled steps is particularly advantageous.
  • the operator can hand over the manual operation control to the feed automation, whereby the feed of the laser catheter can be carried out, for example, relative to the piercing point on the paracentesis within the eye.
  • a feed unit can be formed, for example, by piezo actuators, which move the optical fiber arrangement step-by-step and in the smallest path sections into the interior of the tissue to be ablated due to their own contraction in length.
  • a metal plate at the distal end at a distance from the light exit surface of the laser catheter, which generates pulsed light radiation which serves to dissolve the tissue located behind the metal plate.
  • the metal plate is preferably attached parallel to the inclination of the light exit surface in order to get correspondingly close to the tissue of the trabecular mechanism to be removed.
  • Fig. 2 handpiece of the laser catheter with protruding distally
  • FIG. 3 a, b light exit surface of the fiber arrangement
  • FIG. 4 a, b integration of the fiber arrangement into an endoscope device
  • FIG. 5 distal end of the fiber arrangement with metal plate.
  • Figure 1 shows the chamber angle, as already described above in relation to the prior art.
  • the sponge-like trabecular structure T and the Schlemm's canal S behind it through which the aqueous humor is drained from the inside of the eye can also be seen from the illustration.
  • the trabecular system which closes over time and is one of the causes of glaucoma, must be perforated so that the outflow of the aqueous humor is largely unimpeded.
  • the handpiece 1 shows a handpiece 1 which enables the surgeon to precisely actuate the laser catheter 2 which passes axially through the handpiece 1.
  • the handpiece 1 which has an outer contour ergonomically adapted to the hand of the surgeon, connects a flexibly designed light guide cable 3 to the laser catheter 2, which projects out of the handpiece 1 on the distal side.
  • the flexibly trained Optical fiber 3 is connected to a corresponding light source (not shown), for example an excimer laser.
  • the laser catheter 2 has a light exit surface 4 which is cut off obliquely to the longitudinal axis of the catheter and which is shown in cross section according to FIG. 3a.
  • the intersection angle ⁇ , which the light exit surface includes with the fiber longitudinal axis, preferably has 37 ⁇ .
  • the laser catheter is sheathed from a light-conducting fiber arrangement 5 and via an adhesive layer 6 with a support material 7 surrounding the fiber arrangement 5.
  • the light-transparent fiber arrangement 5 is placed in the center of the laser catheter arrangement and is connected to the support material 7 via an adhesive layer 6, which is designed as an adhesive layer.
  • the laser catheter Due to the slanted light exit surface, the laser catheter can be placed flush with the trabecular mechanism in the chamber angle of the eye and can come into direct contact there. Due to the beveled light exit end of the laser catheter, it lies flush against the tissue area to be treated without locally squeezing or compressing it, which would be the case with a laser catheter with a perpendicularly cut light exit end.
  • FIG 4a shows an endoscope device which provides a plurality of proximal working areas 8, 9 and 10.
  • the laser catheter 2 Through the working channel 8, the laser catheter 2, through the working channel 9 a visual optics 11 and through the Working channel 10 fed a flushing device 12.
  • the laser catheter 2 At the distal end of the endoscope, the laser catheter 2 can be advanced distally.
  • FIG. 4b shows two hollow cannulas 13, into which a plurality of laser catheters 2 - two or three laser catheters are shown in the figure - are introduced.
  • the individual laser catheters 2 can be individually pushed out of the hollow cannula 13 distally and thus represent different light application foci. In this way, a large number of different tissue ablation sites within the eye can be achieved with the aid of only a single hollow channel that is guided into the interior of the eye.
  • FIG. 5 shows the distal end of the laser catheter 2 with a metal plate 14 which is arranged distally away from the light exit surface. With the help of the metal plate 14, it is possible to generate shock waves through which tissue can be broken up.
  • Handpiece laser catheter optical fiber light exit surface fiber arrangement adhesive layer support material 9.10 working channel 1 viewing channel 2 flushing device 3 hollow cannula 4 metal plate

Landscapes

  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Laser Surgery Devices (AREA)

Abstract

Cathéter à laser pour le traitement du glaucome, doté d'un système de fibres (5) guidant la lumière à l'extrémité proximale desquelles de la lumière peut être introduite dans lesdites fibres et à l'extrémité distale desquelles se trouve une surface de sortie (4) de lumière par laquelle la lumière sort de la fibre. La présente invention se caractérise en ce que la surface de sortie de lumière présente, par rapport à l'axe longitudinal du système de fibres, un angle de 30 à 70° environ, et de préférence de 37°.
PCT/EP2000/004094 1999-05-05 2000-05-05 Dispositif permettant de traiter le glaucome WO2000067687A1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP00938627A EP1107715A1 (fr) 1999-05-05 2000-05-05 Dispositif permettant de traiter le glaucome
AU53934/00A AU5393400A (en) 1999-05-05 2000-05-05 Device for treating glaucoma of the eye

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19920615.5 1999-05-05
DE1999120615 DE19920615A1 (de) 1999-05-05 1999-05-05 Vorrichtung zur Glaucornbehandlung des Auges

Publications (1)

Publication Number Publication Date
WO2000067687A1 true WO2000067687A1 (fr) 2000-11-16

Family

ID=7907022

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2000/004094 WO2000067687A1 (fr) 1999-05-05 2000-05-05 Dispositif permettant de traiter le glaucome

Country Status (4)

Country Link
EP (1) EP1107715A1 (fr)
AU (1) AU5393400A (fr)
DE (1) DE19920615A1 (fr)
WO (1) WO2000067687A1 (fr)

Cited By (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001089437A2 (fr) * 2000-05-19 2001-11-29 Berlin Michael S Systeme d'administration et procede d'utilisation avec les yeux
EP1216671A2 (fr) * 2000-12-14 2002-06-26 Glautec AG Dispositif de traitement du glaucome
EP1250900A2 (fr) * 2001-04-18 2002-10-23 Glautec AG Dispositif de traitement du glaucome
WO2002056805A3 (fr) * 2001-01-18 2002-11-21 Univ California Instrument chirurgical et methode de traitement du glaucome peu invasifs
US8679089B2 (en) 2001-05-21 2014-03-25 Michael S. Berlin Glaucoma surgery methods and systems
US9603741B2 (en) 2000-05-19 2017-03-28 Michael S. Berlin Delivery system and method of use for the eye
US10064757B2 (en) 2011-05-05 2018-09-04 Michael S. Berlin Methods and apparatuses for the treatment of glaucoma using visible and infrared ultrashort laser pulses
US10285853B2 (en) 2013-03-15 2019-05-14 Glaukos Corporation Systems and methods for delivering an ocular implant to the suprachoroidal space within an eye
US10285856B2 (en) 2001-08-28 2019-05-14 Glaukos Corporation Implant delivery system and methods thereof for treating ocular disorders
US10363168B2 (en) 2011-06-14 2019-07-30 Ivantis, Inc. Ocular implants for delivery into the eye
US10406029B2 (en) 2001-04-07 2019-09-10 Glaukos Corporation Ocular system with anchoring implant and therapeutic agent
US10406025B2 (en) 2009-07-09 2019-09-10 Ivantis, Inc. Ocular implants and methods for delivering ocular implants into the eye
US10485701B2 (en) 2002-04-08 2019-11-26 Glaukos Corporation Devices and methods for glaucoma treatment
US10485702B2 (en) 2000-04-14 2019-11-26 Glaukos Corporation System and method for treating an ocular disorder
US10492949B2 (en) 2009-07-09 2019-12-03 Ivantis, Inc. Single operator device for delivering an ocular implant
US10492950B2 (en) 1999-04-26 2019-12-03 Glaukos Corporation Shunt device and method for treating ocular disorders
US10517759B2 (en) 2013-03-15 2019-12-31 Glaukos Corporation Glaucoma stent and methods thereof for glaucoma treatment
US10537474B2 (en) 2008-03-05 2020-01-21 Ivantis, Inc. Methods and apparatus for treating glaucoma
US10709547B2 (en) 2014-07-14 2020-07-14 Ivantis, Inc. Ocular implant delivery system and method
US10828195B2 (en) 2006-11-10 2020-11-10 Glaukos Corporation Uveoscleral shunt and methods for implanting same
US10828473B2 (en) 2001-04-07 2020-11-10 Glaukos Corporation Ocular implant delivery system and methods thereof
US10959941B2 (en) 2014-05-29 2021-03-30 Glaukos Corporation Implants with controlled drug delivery features and methods of using same
US11026836B2 (en) 2012-04-18 2021-06-08 Ivantis, Inc. Ocular implants for delivery into an anterior chamber of the eye
US11116625B2 (en) 2017-09-28 2021-09-14 Glaukos Corporation Apparatus and method for controlling placement of intraocular implants
US11135088B2 (en) 2011-12-19 2021-10-05 Ivantis Inc. Delivering ocular implants into the eye
US11197779B2 (en) 2015-08-14 2021-12-14 Ivantis, Inc. Ocular implant with pressure sensor and delivery system
US11318047B2 (en) 2019-07-01 2022-05-03 Michael S. Berlin Image guidance methods and apparatus for glaucoma surgery
US11540940B2 (en) 2021-01-11 2023-01-03 Alcon Inc. Systems and methods for viscoelastic delivery
US11712369B2 (en) 2012-11-28 2023-08-01 Alcon Inc. Apparatus for delivering ocular implants into an anterior chamber of the eye
US11744734B2 (en) 2007-09-24 2023-09-05 Alcon Inc. Method of implanting an ocular implant
US11925578B2 (en) 2015-09-02 2024-03-12 Glaukos Corporation Drug delivery implants with bi-directional delivery capacity
US11938058B2 (en) 2015-12-15 2024-03-26 Alcon Inc. Ocular implant and delivery system
US11992551B2 (en) 2021-03-26 2024-05-28 Glaukos Corporation Implants with controlled drug delivery features and methods of using same

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005026323A1 (de) * 2005-06-07 2006-12-14 ACTO Aachener Centrum für Technologietransfer in der Ophthalmologie e.V. Vorrichtung zum Korrigieren einer Fehlsichtigkeit eines Auges
WO2020121061A2 (fr) * 2018-12-13 2020-06-18 Ioptima Ltd. Procédés et systèmes destinés à une technique assistée par laser de chirurgie mini-invasive ab interno d'un glaucome
US11672475B2 (en) 2019-04-19 2023-06-13 Elios Vision, Inc. Combination treatment using ELT
US11389239B2 (en) 2019-04-19 2022-07-19 Elios Vision, Inc. Enhanced fiber probes for ELT
US11103382B2 (en) 2019-04-19 2021-08-31 Elt Sight, Inc. Systems and methods for preforming an intraocular procedure for treating an eye condition
US20200330275A1 (en) * 2019-04-19 2020-10-22 Elt Sight, Inc. Combination treatment using phaco and elt
US11076933B2 (en) 2019-04-19 2021-08-03 Elt Sight, Inc. Authentication systems and methods for an excimer laser system
US11076992B2 (en) * 2019-04-19 2021-08-03 Elt Sight, Inc. Methods of transverse placement in ELT
US11234866B2 (en) 2019-04-19 2022-02-01 Elios Vision, Inc. Personalization of excimer laser fibers
US11903876B1 (en) 2022-08-30 2024-02-20 Elios Vision, Inc. Systems and methods for prophylactic treatment of an eye using an excimer laser unit
US11918516B1 (en) 2022-08-30 2024-03-05 Elios Vision, Inc. Systems and methods for treating patients with closed-angle or narrow-angle glaucoma using an excimer laser unit
US11877951B1 (en) 2022-08-30 2024-01-23 Elios Vision, Inc. Systems and methods for applying excimer laser energy with transverse placement in the eye

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4607622A (en) * 1985-04-11 1986-08-26 Charles D. Fritch Fiber optic ocular endoscope
WO1989003202A2 (fr) * 1987-10-14 1989-04-20 Schneider Richard T Procede et dispositif d'emulsification au laser
US4846172A (en) * 1987-05-26 1989-07-11 Berlin Michael S Laser-delivery eye-treatment method
WO1991017793A1 (fr) * 1990-05-16 1991-11-28 Sunrise Technologies, Inc. Sonde a fibre optique et sclerostomie a laser
US5360425A (en) * 1990-08-17 1994-11-01 Candela Laser Corporation Sclerostomy method and apparatus
US5423800A (en) * 1992-10-19 1995-06-13 The University Of Miami Laser scleral buckling method and instruments therefor
US5865831A (en) * 1996-04-17 1999-02-02 Premier Laser Systems, Inc. Laser surgical procedures for treatment of glaucoma

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4865029A (en) * 1986-04-24 1989-09-12 Eye Research Institute Of Retina Foundation Endophotocoagulation probe
DE19718139A1 (de) * 1997-04-30 1998-11-05 Aesculap Meditec Gmbh Verfahren und Anordnung zur Phacoemulsifikation

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4607622A (en) * 1985-04-11 1986-08-26 Charles D. Fritch Fiber optic ocular endoscope
US4846172A (en) * 1987-05-26 1989-07-11 Berlin Michael S Laser-delivery eye-treatment method
WO1989003202A2 (fr) * 1987-10-14 1989-04-20 Schneider Richard T Procede et dispositif d'emulsification au laser
WO1991017793A1 (fr) * 1990-05-16 1991-11-28 Sunrise Technologies, Inc. Sonde a fibre optique et sclerostomie a laser
US5360425A (en) * 1990-08-17 1994-11-01 Candela Laser Corporation Sclerostomy method and apparatus
US5423800A (en) * 1992-10-19 1995-06-13 The University Of Miami Laser scleral buckling method and instruments therefor
US5865831A (en) * 1996-04-17 1999-02-02 Premier Laser Systems, Inc. Laser surgical procedures for treatment of glaucoma

Cited By (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10568762B2 (en) 1999-04-26 2020-02-25 Glaukos Corporation Stent for treating ocular disorders
US10492950B2 (en) 1999-04-26 2019-12-03 Glaukos Corporation Shunt device and method for treating ocular disorders
US10485702B2 (en) 2000-04-14 2019-11-26 Glaukos Corporation System and method for treating an ocular disorder
US10390993B1 (en) 2000-05-19 2019-08-27 Ivantis, Inc. Delivery system and method of use for the eye
US10687978B2 (en) 2000-05-19 2020-06-23 Ivantis, Inc. Delivery system and method of use for the eye
WO2001089437A3 (fr) * 2000-05-19 2002-08-29 Michael S Berlin Systeme d'administration et procede d'utilisation avec les yeux
WO2001089437A2 (fr) * 2000-05-19 2001-11-29 Berlin Michael S Systeme d'administration et procede d'utilisation avec les yeux
US10383689B2 (en) 2000-05-19 2019-08-20 Michael S. Berlin Delivery system and method of use for the eye
US10335314B2 (en) 2000-05-19 2019-07-02 Ivantis, Inc. Delivery system and method of use for the eye
US10195080B2 (en) 2000-05-19 2019-02-05 Michael S. Berlin Glaucoma surgery methods and systems
US9603741B2 (en) 2000-05-19 2017-03-28 Michael S. Berlin Delivery system and method of use for the eye
US10159601B2 (en) 2000-05-19 2018-12-25 Ivantis, Inc. Delivery system and method of use for the eye
US9820883B2 (en) 2000-05-19 2017-11-21 Michael S. Berlin Method for treating glaucoma
US9833357B2 (en) 2000-05-19 2017-12-05 Michael S. Berlin Delivery system and method of use for the eye
EP1216671A3 (fr) * 2000-12-14 2003-11-19 Glautec AG Dispositif de traitement du glaucome
EP1216671A2 (fr) * 2000-12-14 2002-06-26 Glautec AG Dispositif de traitement du glaucome
US10085885B2 (en) 2001-01-18 2018-10-02 The Regents Of The University Of California Minimally invasive glaucoma surgical instrument and method
US7785321B2 (en) 2001-01-18 2010-08-31 The Regents Of The University Of California Minimally invasive glaucoma surgical instrument and method
US9999544B2 (en) 2001-01-18 2018-06-19 The Regents Of The University Of California Minimally invasive glaucoma surgical instrument and method
US6979328B2 (en) 2001-01-18 2005-12-27 The Regents Of The University Of California Minimally invasive glaucoma surgical instrument and method
US9226850B2 (en) 2001-01-18 2016-01-05 The Regents Of The University Of California Minimally invasive glaucoma surgical instrument and method
WO2002056805A3 (fr) * 2001-01-18 2002-11-21 Univ California Instrument chirurgical et methode de traitement du glaucome peu invasifs
US8512321B2 (en) 2001-01-18 2013-08-20 The Regents Of The University Of California Minimally invasive glaucoma surgical instrument and method
US10744033B2 (en) 2001-01-18 2020-08-18 The Regents Of The University Of California Minimally invasive glaucoma surgical instrument and method
US10406029B2 (en) 2001-04-07 2019-09-10 Glaukos Corporation Ocular system with anchoring implant and therapeutic agent
US10828473B2 (en) 2001-04-07 2020-11-10 Glaukos Corporation Ocular implant delivery system and methods thereof
EP1250900A3 (fr) * 2001-04-18 2002-11-06 Glautec AG Dispositif de traitement du glaucome
EP1250900A2 (fr) * 2001-04-18 2002-10-23 Glautec AG Dispositif de traitement du glaucome
US8679089B2 (en) 2001-05-21 2014-03-25 Michael S. Berlin Glaucoma surgery methods and systems
US9642746B2 (en) 2001-05-21 2017-05-09 Michael Berlin Glaucoma surgery methods and systems
US10285856B2 (en) 2001-08-28 2019-05-14 Glaukos Corporation Implant delivery system and methods thereof for treating ocular disorders
US10485701B2 (en) 2002-04-08 2019-11-26 Glaukos Corporation Devices and methods for glaucoma treatment
US10828195B2 (en) 2006-11-10 2020-11-10 Glaukos Corporation Uveoscleral shunt and methods for implanting same
US11744734B2 (en) 2007-09-24 2023-09-05 Alcon Inc. Method of implanting an ocular implant
US10537474B2 (en) 2008-03-05 2020-01-21 Ivantis, Inc. Methods and apparatus for treating glaucoma
US11504275B2 (en) 2008-03-05 2022-11-22 Alcon Inc. Methods and apparatus for treating glaucoma
US10492949B2 (en) 2009-07-09 2019-12-03 Ivantis, Inc. Single operator device for delivering an ocular implant
US11918514B2 (en) 2009-07-09 2024-03-05 Alcon Inc. Single operator device for delivering an ocular implant
US11464675B2 (en) 2009-07-09 2022-10-11 Alcon Inc. Single operator device for delivering an ocular implant
US10406025B2 (en) 2009-07-09 2019-09-10 Ivantis, Inc. Ocular implants and methods for delivering ocular implants into the eye
US11596546B2 (en) 2009-07-09 2023-03-07 Alcon Inc. Ocular implants and methods for delivering ocular implants into the eye
US11857463B2 (en) 2011-05-05 2024-01-02 Michael S. Berlin Methods for the treatment of glaucoma using visible and infrared ultrashort laser pulses
US10765559B2 (en) 2011-05-05 2020-09-08 Michael S. Berlin Methods and apparatuses for the treatment of glaucoma using visible and infrared ultrashort laser pulses
US11039958B2 (en) 2011-05-05 2021-06-22 Michael S. Berlin Methods and apparatuses for the treatment of glaucoma using visible and infrared ultrashort laser pulses
US11510813B2 (en) 2011-05-05 2022-11-29 Michael S. Berlin Methods and apparatuses for the treatment of glaucoma using visible and infrared ultrashort laser pulses
US10064757B2 (en) 2011-05-05 2018-09-04 Michael S. Berlin Methods and apparatuses for the treatment of glaucoma using visible and infrared ultrashort laser pulses
US11974950B2 (en) 2011-05-05 2024-05-07 Michael S. Berlin Methods and systems for the treatment of glaucoma using visible and infrared ultrashort laser pulses
US10363168B2 (en) 2011-06-14 2019-07-30 Ivantis, Inc. Ocular implants for delivery into the eye
US11135088B2 (en) 2011-12-19 2021-10-05 Ivantis Inc. Delivering ocular implants into the eye
US11026836B2 (en) 2012-04-18 2021-06-08 Ivantis, Inc. Ocular implants for delivery into an anterior chamber of the eye
US11712369B2 (en) 2012-11-28 2023-08-01 Alcon Inc. Apparatus for delivering ocular implants into an anterior chamber of the eye
US10517759B2 (en) 2013-03-15 2019-12-31 Glaukos Corporation Glaucoma stent and methods thereof for glaucoma treatment
US10285853B2 (en) 2013-03-15 2019-05-14 Glaukos Corporation Systems and methods for delivering an ocular implant to the suprachoroidal space within an eye
US11523938B2 (en) 2013-03-15 2022-12-13 Glaukos Corporation Systems and methods for delivering an ocular implant to the suprachoroidal space within an eye
US11559430B2 (en) 2013-03-15 2023-01-24 Glaukos Corporation Glaucoma stent and methods thereof for glaucoma treatment
US10959941B2 (en) 2014-05-29 2021-03-30 Glaukos Corporation Implants with controlled drug delivery features and methods of using same
US10709547B2 (en) 2014-07-14 2020-07-14 Ivantis, Inc. Ocular implant delivery system and method
US11197779B2 (en) 2015-08-14 2021-12-14 Ivantis, Inc. Ocular implant with pressure sensor and delivery system
US11925578B2 (en) 2015-09-02 2024-03-12 Glaukos Corporation Drug delivery implants with bi-directional delivery capacity
US11938058B2 (en) 2015-12-15 2024-03-26 Alcon Inc. Ocular implant and delivery system
US11116625B2 (en) 2017-09-28 2021-09-14 Glaukos Corporation Apparatus and method for controlling placement of intraocular implants
US11583444B2 (en) 2019-07-01 2023-02-21 Michael S. Berlin Image guidance methods and apparatus for glaucoma surgery
US11590024B2 (en) 2019-07-01 2023-02-28 Michael S. Berlin Image guidance methods and apparatus for glaucoma surgery
US11759357B2 (en) 2019-07-01 2023-09-19 Michael S. Berlin Image guidance apparatus for glaucoma surgery
US11850186B2 (en) 2019-07-01 2023-12-26 Michael S. Berlin Image guidance apparatus for glaucoma surgery
US11318047B2 (en) 2019-07-01 2022-05-03 Michael S. Berlin Image guidance methods and apparatus for glaucoma surgery
US11318046B2 (en) 2019-07-01 2022-05-03 Michael S. Berlin Image guidance methods and apparatus for glaucoma surgery
US11583443B2 (en) 2019-07-01 2023-02-21 Michael S. Berlin Image guidance methods and apparatus for glaucoma surgery
US11723805B2 (en) 2019-07-01 2023-08-15 Michael S. Berlin Image guidance methods and apparatus for glaucoma surgery
US11318045B2 (en) 2019-07-01 2022-05-03 Michael S. Berlin Image guidance methods and apparatus for glaucoma surgery
US11540940B2 (en) 2021-01-11 2023-01-03 Alcon Inc. Systems and methods for viscoelastic delivery
US11992551B2 (en) 2021-03-26 2024-05-28 Glaukos Corporation Implants with controlled drug delivery features and methods of using same
US11992437B2 (en) 2021-05-07 2024-05-28 Alcon Inc. Ocular implants for delivery into an anterior chamber of the eye

Also Published As

Publication number Publication date
EP1107715A1 (fr) 2001-06-20
AU5393400A (en) 2000-11-21
DE19920615A1 (de) 2000-12-07

Similar Documents

Publication Publication Date Title
WO2000067687A1 (fr) Dispositif permettant de traiter le glaucome
EP0858788B1 (fr) Dispositif médical, particulièrement pour diminuer la tension intraoculaire
DE2804058C3 (de) Medizinisches Gerät zur Entfernung von Fremdkörpern aus einem Körperhohlraum
DE19714475C1 (de) Vorrichtung für das Entfernen von Körpersubstanzen
EP1446079B1 (fr) Dispositif permettant d'effectuer des interventions ophtalmologiques
EP1216671A2 (fr) Dispositif de traitement du glaucome
CH674453A5 (fr)
DE3601453A1 (de) Endoskop zur gewebeabtragung
DE19523959A1 (de) Endoskop
EP1014902A1 (fr) Dispositif permettant un acces a l'espace sous-retinien d'un oeil
EP3876819B1 (fr) Instrument endoscopique
DE3917663C2 (fr)
AT410055B (de) Laserskalpell
EP0218809B1 (fr) Sonde de guidage
DE4408746A1 (de) Laserkatheter zur Bypass-Chirurgie
EP1153583A1 (fr) Dispositif de traitement du glaucome
WO2010060443A1 (fr) Système pour l'ophtalmologie ou la dermatologie
DE19826311C2 (de) Laserresektoskop
EP0707831A1 (fr) Dispositif pour l'ablation de tissue dans des canaux intracorporels utilisant un cathéter à laser
DD263447A1 (de) Anordnung zur operativen behandlung der augenhornhaut
EP0446799A2 (fr) Appareil pour le balayage par le gaz d'un guide d'onde pour laser à CO2
EP0999811B1 (fr) Dispositif pour elargir et reconstituer le canal lacrymal au niveau de l'oeil humain
EP3845209B1 (fr) Pièce à main pour phaco-émulsification
DE3833361C2 (de) Katheter für die Angioplastie
DE3739385A1 (de) Vorrichtung zum abtragen von gewebe, insbesondere von knorpelgewebe, im gelenkbereich

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US UZ VN YU ZW

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): GH GM KE LS MW SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
WWE Wipo information: entry into national phase

Ref document number: 2000938627

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 2000938627

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 09959699

Country of ref document: US

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

WWW Wipo information: withdrawn in national office

Ref document number: 2000938627

Country of ref document: EP

NENP Non-entry into the national phase

Ref country code: JP