WO2000006181A1 - Medicament pour le traitement d'aphtes buccaux recurrents et du syndrome de behcet - Google Patents
Medicament pour le traitement d'aphtes buccaux recurrents et du syndrome de behcet Download PDFInfo
- Publication number
- WO2000006181A1 WO2000006181A1 PCT/CN1998/000315 CN9800315W WO0006181A1 WO 2000006181 A1 WO2000006181 A1 WO 2000006181A1 CN 9800315 W CN9800315 W CN 9800315W WO 0006181 A1 WO0006181 A1 WO 0006181A1
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- WO
- WIPO (PCT)
- Prior art keywords
- weight
- parts
- medicine
- asarum
- dry
- Prior art date
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/718—Coptis (goldthread)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/58—Reptiles
- A61K35/583—Snakes; Lizards, e.g. chameleons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/26—Aristolochiaceae (Birthwort family), e.g. heartleaf
- A61K36/268—Asarum (wild ginger)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
- A61K36/315—Isatis, e.g. Dyer's woad
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/37—Celastraceae (Staff-tree or Bittersweet family), e.g. tripterygium or spindletree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/50—Fumariaceae (Fumitory family), e.g. bleeding heart
- A61K36/505—Corydalis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8967—Lilium, e.g. tiger lily or Easter lily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Definitions
- the invention relates to a medicine for treating recurrent oral ulcer, and also relates to a medicine for treating Behcet's syndrome, and belongs to the field of Chinese medicine. Background technique
- Recurrent oral ulcer is one of the common oral diseases.
- Clinically the oral mucosa repeatedly appears as isolated small round or oval superficial ulcers. Severe spontaneous pain often affects eating and sleeping during seizures.
- Western medicine treats with topical medication plus Vt. Bl, Vt. B2, Vt. C. Oral hormones are taken short-term by severely stubborn people.
- traditional Chinese medicine divides prescriptions into two types of syndromes, but there are not many traditional Chinese medicine preparations developed for the deficiency and reality.
- Traditional tin preparations, boron tincture and other external preparations and Niuhuangjiedu pills , Shangqing Wan, etc. can only cure its symptoms but not its root causes, and cannot solve the problem of recurrence of the disease. Disclosure of invention
- the object of the present invention is to provide a traditional Chinese medicine for effectively treating recurrent oral ulcers and Behcet's syndrome.
- the medicine of the present invention is mainly made of the following weight ratio of raw materials (based on parts by weight): Coptis chinensis 6-9 parts bamboo leaves 3-6 parts
- the preferred weight (parts) ratio of the medicine of the present invention is:
- the conventional Chinese medicine preparation method can be used to prepare the medicine of the present invention into any common dosage form, such as pills, tinctures, tablets, oral liquids, ointments, and the like.
- conventional excipients such as starch, can be added to the above raw materials.
- the preparation method of the medicine of the present invention is as follows:
- the bamboo leaves, Coptis chinensis, Ban GmbH, Yinhua, Kudingding, Lily, and Shengdi 7 kinds of medicines in the weight ratio are boiled twice, and the amount of water added each time is better than the medicated surface, and the two decoctions are combined.
- the filtrate 1 is obtained by filtration, and the weight ratio of Asarum is routinely extracted by adding water to collect volatile oil for use.
- the asarum decoction and the filtrate 1 are combined and concentrated to an extract having a specific gravity of 1.35, and 90-95% is added.
- the ethanol was subjected to alcohol precipitation, the ethanol was recovered and concentrated, and dried at 45-50 to obtain a dry diffuse paste 1.
- the medicament of the invention has the functions of clearing heat and purging fire, anti-inflammatory, antibacterial, cooling blood and collecting sores, and is used for treating recurrent oral ulcer and Behcet's syndrome.
- the medicine of the present invention uses Coptis chinensis as a junior medicine.
- Coptis chinensis has bitter cold, returns to the liver, stomach and large intestine meridians, clears away heat and dampness, purifies fire and detoxifies, Youshan clears fire, relieves heart and stomach, and treats sores.
- Coptis chinensis is both a medicine for the heart and spleen and a cure for sores. This medicine uses bitter dices, isatis root, and comfrey as the medicine.
- This three-drug medicine clears heat and detoxifies cooling blood, and helps the medicine Huanglian clears heat and detoxifies and treats ulcers.
- This medicine uses silver flowers, bamboo leaves, snake gallbladder, habitat, and lily as adjuvant. Yinhua, sweetness and coldness, returning to the heart, heart and stomach meridians, clearing heat and detoxifying, relieving wind and heat, and relieving pain and swelling, it is an essential medicine for treating all the symptoms of pain, swelling, sore and yang.
- Lily, sweet and cold belongs to the Heart and Heart Meridian, moisturizes the lungs and relieves cough, clears the heart and soothe the nerves.
- the above five medicines, silver flowers, bamboo leaves, and snake bile focus on clearing heat and detoxifying; habitat and lily are focusing on nourishing yin and lowering fire, cooling blood and sore, and together assisting the monarch and minister's products to clearing heat and detoxifying, and also have the function of nourishing yin and cooling blood, so it ’s medicine.
- Asarum in the recipe Xin Wen of nature and flavor, the lung and kidney meridian, Xin Wen fragrance channeling, Tongqiao Muhan analgesic.
- 'Asarum in the prescription can not only cure the cold and cold effects of various medicines, but also can introduce the drug to reach the skin of the hole, so it is the adjuvant. Compatible with all parties, receiving heat and purging fire, cooling blood and sores.
- the clinical effect of treating Behcet's syndrome can be enhanced, the nodular erythema can be quickly subsided, the Ling's joint pain can be quickly eliminated, and the remission period can be extended.
- Ganoderma lucidum in Fangzhong has the function of righting, and Tripterygium wilfordii has the effect of enhancing immunity. It has been proved by clinical observation that the cure rate for Behcet's syndrome is over 90%.
- Watermelon cream throat slice batch number 9710025, provided by Guilin Sanjin Pharmaceutical Group Co., Ltd .: 40 New Zealand rabbits, both male and female, weighing 2.0-2.5kg, were pressed with a cotton swab soaked in acetic acid for about 15 Modeling in 2 seconds, mucosal ulcer diameter 5mm, after modeling The rabbits were divided into 4 groups of 10 animals each, of which 2 groups were treated with different doses of the drug of the triple tablets of the present invention, 1 group was treated with watermelon frost throat tablets, and 1 group was used with equal volume Water control group.
- the triple tablet stream extract (2.54g crude drug / ml) was formulated with distilled water into 50.4g and 100.8g crude drug / 100ml suspension for the treatment group of rabbits; the watermelon cream moisturizing throat tablets were pulverized into 157g with distilled water. Eighty eight hundred milliliters were used for the rabbit comparison group.
- the dosage of the triple tablets was 5.04g and 10.08g crude drugs / kg; the watermelon cream throat tablet was 15.7g / kg.
- the treatment group and the treatment comparison group were administered at the above doses, and the control group was given an equal volume of water.
- the method of administration is intragastric administration, once a day for 7 consecutive days. Observe the local redness and swelling symptoms, the amount of exudates, the ulcer healing time, and kill the rabbits on the eighth day. Take the tongue first and then observe the pathological section. .
- the medicine of the present invention was clinically observed by the Department of Stomatology of the First affiliated Hospital of Hunan College of Traditional Chinese Medicine, with a total effective rate of 93% and a significant effective rate of 57%.
- the male to female ratio was 0.3: 1.
- Oral ulceration points are mostly born at the root of the tongue, with fewer and smaller ulceration points.
- the surface of the ulcer is gray and white, and the surrounding mucosa is reddish and swollen. May be accompanied by dry tongue, dry throat, weak waist and knees, red tongue and less moss, and pulse count.
- Occurred in the oral mucosa such as lips, tongue, cheeks, floor of mouth, soft palate and so on.
- the ulcer is round or oval, with a concave center and a pale yellow pseudomembrane.
- Mild aphthous ulcers about 2-3mm in diameter, less blemishes, and usually heal within 1 to 2 weeks, leaving no scars when cured.
- Stomatitis-type aphthous ulcers Up to a dozen or dozen ulcers, which can be accompanied by systemic symptoms such as fever.
- Peripheral aphthous ulcer Diameter is about 5-20mm. The ulcer is deep to the mucous glands. The course of the ulcer can be several weeks to several months, and there will be white scars after healing.
- Oral ulcers are mostly born at the base of the tongue, with fewer and smaller ulceration points.
- the surface of the ulcer is gray and white, and the surrounding mucosa is slightly red and swollen. May be accompanied by dry tongue, dry throat, soft waist and knees, red tongue and less moss, and thin pulse.
- the bamboo leaves, Coptis chinensis, isatis root, silver flower, bitter sage, lily, raw ground are mixed according to the above weight ratio, and they are boiled twice with water. The first time, add 8 times the amount of water, cook for 1.5 hours, and add 6 times the second time.
- For the extract with a specific gravity of 1.35 add 90-95% ethanol to the diffuser paste, stir, precipitate, recover the ethanol, and concentrate, and dry at 45-50 ° C to prepare 3.9 g of dry diffuser paste for later use. Comfrey was added with 90-95% ethanol for reflux extraction. The extract was recovered ethanol, concentrated and dried at 50 ° C to obtain 0.18 g of dry diffuse cream. The two dry diffuse creams were combined, mixed with snake bile powder, and pulverized into fine powder. Add auxiliary materials to make granules, dry them, spray with Asarum volatile oil, and press into tablets.
- the diffused paste was added with 90-95% ethanol, stirred, precipitated to recover the ethanol and concentrated, and dried at 45-5CTC to prepare 3.9 g of dry extract for later use.
- the comfrey was extracted with 90-95% ethanol under reflux.
- the extract was recovered ethanol, concentrated and dried at 50 ° C to obtain 0.18 g of dry diffuse cream.
- the two dry diffuse creams were combined, mixed with snake bile powder, and pulverized into fine powder. Powder, adding auxiliary materials to make granules, and drying, spraying asarum volatile oil, and pressing into tablets.
- the medicament for treating recurrent oral ulcers and Behcet's syndrome has the functions of clearing heat and purging fire, anti-inflammatory, antibacterial, cooling blood and sore.
- Animal tests and clinical efficacy observations on outpatients confirm that the medicines of the present invention have a significant therapeutic effect on oral ulcers.
- the cure rate for oral ulcers can reach 80-100%, and the cure rate for Behcet's syndrome can reach more than 90%. Therefore, the medicine of the present invention can be described as a good medicine that can be widely used, has quick effects and a high cure rate.
Description
Claims
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2000562035A JP2002521454A (ja) | 1998-07-24 | 1998-12-28 | 口腔内での再発性潰瘍およびベーチェット症候群を処置するための薬剤 |
KR1020007003144A KR20010015618A (ko) | 1998-07-24 | 1998-12-28 | 구강내 재발성 궤양 및 베체트 증후군 치료제 |
US09/509,331 US6217880B1 (en) | 1998-07-24 | 1998-12-28 | Medicament for treating recurrent ulcer of mouth and behcet's syndrome |
CA002304596A CA2304596A1 (en) | 1998-07-24 | 1998-12-28 | A medicament for treating recurrent ulcer of mouth and behcet's syndrome |
AU44804/99A AU749922B2 (en) | 1998-07-24 | 1998-12-28 | A medicament for treating recurrent ulcer of mouth and Behcet's syndrome |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN98103423.3 | 1998-07-24 | ||
CN98103423A CN1060392C (zh) | 1998-07-24 | 1998-07-24 | 治疗复发性口腔溃疡和白塞氏综合症的药物 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2000006181A1 true WO2000006181A1 (fr) | 2000-02-10 |
Family
ID=5217901
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/CN1998/000315 WO2000006181A1 (fr) | 1998-07-24 | 1998-12-28 | Medicament pour le traitement d'aphtes buccaux recurrents et du syndrome de behcet |
Country Status (7)
Country | Link |
---|---|
US (1) | US6217880B1 (zh) |
JP (1) | JP2002521454A (zh) |
KR (1) | KR20010015618A (zh) |
CN (1) | CN1060392C (zh) |
AU (1) | AU749922B2 (zh) |
CA (1) | CA2304596A1 (zh) |
WO (1) | WO2000006181A1 (zh) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100377813B1 (ko) * | 2000-09-06 | 2003-03-29 | 이시협 | 대나무 추출물을 함유하는 신규한 치료용 조성물 및 이조성물을 포함하는 치료제 |
CN107789453A (zh) * | 2016-08-30 | 2018-03-13 | 天津太平洋制药有限公司 | 一种治疗口疮的中药组合物及其制备方法 |
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CN1089002C (zh) * | 1999-12-22 | 2002-08-14 | 余美旺 | 治疗口腔溃疡及白塞氏病的中成药 |
US7341745B2 (en) * | 2003-02-07 | 2008-03-11 | Arizona Health Consulting, Llc | Method for decreasing nicotine and other substance use in humans |
CN101264178B (zh) * | 2008-04-26 | 2010-09-29 | 刘翠平 | 治疗恶性皮肤溃疡灶中药洗剂的制备方法 |
US9421236B2 (en) * | 2010-12-17 | 2016-08-23 | Johnson & Johnson Consumer Inc. | Compositions comprising Lilium siberia extracts and uses thereof |
CN102552521A (zh) * | 2011-12-29 | 2012-07-11 | 侯春华 | 一种治疗白塞氏病的中药组合物 |
CN102657811B (zh) * | 2012-06-01 | 2013-09-25 | 朱新华 | 一种治疗口腔溃疡的口服液 |
CN103610957A (zh) * | 2013-10-29 | 2014-03-05 | 于巧媛 | 一种治疗结节性红斑的中药组合物 |
CN104547663A (zh) * | 2014-12-17 | 2015-04-29 | 刘长华 | 一种治疗脾胃炽热型口腔溃疡的中药组合物 |
CN104997990A (zh) * | 2015-08-10 | 2015-10-28 | 孙霞 | 一种治疗复发性口腔溃疡的中药 |
CN105497565A (zh) * | 2016-01-15 | 2016-04-20 | 黎余英 | 一种治疗狐惑症的中药 |
CN107898841B (zh) * | 2016-08-31 | 2020-10-13 | 旌德县德源农业开发有限公司 | 一种防治鸡球虫病的药物及其制备方法和应用 |
CN106421487B (zh) * | 2016-11-17 | 2018-01-23 | 扬子江药业集团上海海尼药业有限公司 | 一种中药组合物及其在制备治疗放化疗后皮肤损伤方面药物的应用 |
CN107260939A (zh) * | 2017-07-12 | 2017-10-20 | 范庆春 | 一种治疗口腔病的中药贴及其制备方法 |
CN107550985B (zh) * | 2017-10-19 | 2021-01-15 | 莫兆钦 | 含岗松油的中药组方及其制备方法 |
CN107802774A (zh) * | 2017-12-08 | 2018-03-16 | 淄博亚大制药股份有限公司 | 补脾肺止咳喘的中药及其制备方法 |
CN107929492A (zh) * | 2017-12-22 | 2018-04-20 | 武宣县中医院 | 一种治疗脓肿的壮医外用制剂及其制备方法 |
CN108434334A (zh) * | 2018-06-15 | 2018-08-24 | 王右杰 | 一种治疗乳腺疾病的中药组合物、中药药膏及其制备方法 |
WO2019210593A1 (zh) * | 2018-08-01 | 2019-11-07 | Chen Xia | 防治上呼吸道感染的面料 |
CN109731083A (zh) * | 2019-02-13 | 2019-05-10 | 侯辰阳 | 一种治疗剖宫产术后腹胀的中药组合物 |
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WO1993019765A1 (en) * | 1992-04-06 | 1993-10-14 | Jacques Antoun | Oak and carob bark composition for relieving gastric ulcers |
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US5503822A (en) * | 1994-04-01 | 1996-04-02 | Schulman; Jerome M. | Medicated gel |
CN1152467A (zh) * | 1996-11-05 | 1997-06-25 | 李佩洲 | 治疗复发性口疮的口疮散 |
-
1998
- 1998-07-24 CN CN98103423A patent/CN1060392C/zh not_active Expired - Lifetime
- 1998-12-28 CA CA002304596A patent/CA2304596A1/en not_active Abandoned
- 1998-12-28 WO PCT/CN1998/000315 patent/WO2000006181A1/zh not_active Application Discontinuation
- 1998-12-28 KR KR1020007003144A patent/KR20010015618A/ko not_active Application Discontinuation
- 1998-12-28 US US09/509,331 patent/US6217880B1/en not_active Expired - Lifetime
- 1998-12-28 JP JP2000562035A patent/JP2002521454A/ja not_active Withdrawn
- 1998-12-28 AU AU44804/99A patent/AU749922B2/en not_active Expired
Patent Citations (5)
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WO1993019765A1 (en) * | 1992-04-06 | 1993-10-14 | Jacques Antoun | Oak and carob bark composition for relieving gastric ulcers |
CN1098299A (zh) * | 1993-08-04 | 1995-02-08 | 赵世平 | 用于复发性口疮及各类口疮的甜凉口疮散及其配制方法 |
CN1107347A (zh) * | 1994-02-26 | 1995-08-30 | 叶细本 | 治疗口腔溃疡的中药散剂 |
US5503822A (en) * | 1994-04-01 | 1996-04-02 | Schulman; Jerome M. | Medicated gel |
CN1152467A (zh) * | 1996-11-05 | 1997-06-25 | 李佩洲 | 治疗复发性口疮的口疮散 |
Non-Patent Citations (4)
Title |
---|
Feng Cunan et al. "To Therapy Behcet's Syndrome With Dao Chi Shanjia Wei", in Journal Of Shandong Traditional Chinese Medicine. 1983, (5):43 * |
Li Quansheng "To Therapy 61 Cases Recurrent Ulcer Of Mouth By Combination Of Chinese Traditional And Western Medicine", in Shanxi Traditional Chinese Medicine. 1992, 13(4):175 * |
Meng Heping "The Report Of Therapying 137 Cases Recurrent Ulcer Of Mouth With Kou Chuang Yin", in Journal Of Guiyang College of Traditional Chinese Medicine. 1995, 17(3):48 * |
Qiao Lianhou "Jia Wei Hu HuoTang Therapy 32 Cases Behcet's", In Journal Of Beijing University Of Traditional Chinese Medicine. 1995,18(4):33-34 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100377813B1 (ko) * | 2000-09-06 | 2003-03-29 | 이시협 | 대나무 추출물을 함유하는 신규한 치료용 조성물 및 이조성물을 포함하는 치료제 |
CN107789453A (zh) * | 2016-08-30 | 2018-03-13 | 天津太平洋制药有限公司 | 一种治疗口疮的中药组合物及其制备方法 |
Also Published As
Publication number | Publication date |
---|---|
KR20010015618A (ko) | 2001-02-26 |
CN1203807A (zh) | 1999-01-06 |
CA2304596A1 (en) | 2000-02-10 |
JP2002521454A (ja) | 2002-07-16 |
US6217880B1 (en) | 2001-04-17 |
AU4480499A (en) | 2000-02-21 |
AU749922B2 (en) | 2002-07-04 |
CN1060392C (zh) | 2001-01-10 |
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