WO1999061881A3 - Verfahren und vorrichtung zum prozessieren von kleinstsubstanzmengen - Google Patents

Verfahren und vorrichtung zum prozessieren von kleinstsubstanzmengen Download PDF

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Publication number
WO1999061881A3
WO1999061881A3 PCT/EP1999/003667 EP9903667W WO9961881A3 WO 1999061881 A3 WO1999061881 A3 WO 1999061881A3 EP 9903667 W EP9903667 W EP 9903667W WO 9961881 A3 WO9961881 A3 WO 9961881A3
Authority
WO
WIPO (PCT)
Prior art keywords
extremely small
small substance
processing extremely
substance quantities
reservoir
Prior art date
Application number
PCT/EP1999/003667
Other languages
English (en)
French (fr)
Other versions
WO1999061881A2 (de
Inventor
Markus Kalkum
Martin Mueller
Eckhard Nordhoff
Richard Reinhardt
Holger Eickhoff
Holger Rauth
Original Assignee
Max Planck Gesellschaft
Markus Kalkum
Martin Mueller
Eckhard Nordhoff
Richard Reinhardt
Holger Eickhoff
Holger Rauth
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Max Planck Gesellschaft, Markus Kalkum, Martin Mueller, Eckhard Nordhoff, Richard Reinhardt, Holger Eickhoff, Holger Rauth filed Critical Max Planck Gesellschaft
Priority to EP99926440A priority Critical patent/EP1082594A2/de
Priority to US09/701,203 priority patent/US7105357B1/en
Publication of WO1999061881A2 publication Critical patent/WO1999061881A2/de
Publication of WO1999061881A3 publication Critical patent/WO1999061881A3/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027—General features of the devices
    • G01N2035/1034—Transferring microquantities of liquid
    • G01N2035/1039—Micropipettes, e.g. microcapillary tubes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027—General features of the devices
    • G01N2035/1034—Transferring microquantities of liquid
    • G01N2035/1041—Ink-jet like dispensers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027—General features of the devices
    • G01N2035/1048—General features of the devices using the transfer device for another function
    • G01N2035/1053—General features of the devices using the transfer device for another function for separating part of the liquid, e.g. filters, extraction phase
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2575—Volumetric liquid transfer

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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Devices And Processes Conducted In The Presence Of Fluids And Solid Particles (AREA)

Abstract

Zum Prozessieren von Substanzen im Reservoir (3) einer Mikrotropfen-Dosiereinrichtung (1), erfolgt eine Bewegung eines festen Trägermaterials mit einer bindungsaktiven Oberfläche im Reservoir, und eine Bindung der Substanz auf der Oberfläche des Trägermaterials, das magnetische Partikel (7) oder einen Trägerballen umfaßt.
PCT/EP1999/003667 1998-05-27 1999-05-27 Verfahren und vorrichtung zum prozessieren von kleinstsubstanzmengen WO1999061881A2 (de)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP99926440A EP1082594A2 (de) 1998-05-27 1999-05-27 Verfahren und vorrichtung zum prozessieren von kleinstsubstanzmengen
US09/701,203 US7105357B1 (en) 1998-05-27 1999-05-27 Method and device for processing extremely small substance quantities

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19823719A DE19823719B4 (de) 1998-05-27 1998-05-27 Verfahren zum Aufkonzentrieren von Substanzen
DE19823719.7 1998-05-27

Publications (2)

Publication Number Publication Date
WO1999061881A2 WO1999061881A2 (de) 1999-12-02
WO1999061881A3 true WO1999061881A3 (de) 2000-03-23

Family

ID=7869102

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1999/003667 WO1999061881A2 (de) 1998-05-27 1999-05-27 Verfahren und vorrichtung zum prozessieren von kleinstsubstanzmengen

Country Status (4)

Country Link
US (1) US7105357B1 (de)
EP (1) EP1082594A2 (de)
DE (1) DE19823719B4 (de)
WO (1) WO1999061881A2 (de)

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DE202013003390U1 (de) * 2013-04-11 2014-07-14 Brand Gmbh + Co Kg Pipettiervorrichtung mit einer Mikrodosiereinheit
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US11679028B2 (en) 2019-03-06 2023-06-20 Novartis Ag Multi-dose ocular fluid delivery system
US11826951B2 (en) 2019-09-06 2023-11-28 Cellink Ab Temperature-controlled multi-material overprinting
IL297215A (en) 2020-04-17 2022-12-01 Kedallon Therapeutics Inc A hydrodynamically activated preservative free distribution system
US11938057B2 (en) 2020-04-17 2024-03-26 Bausch + Lomb Ireland Limited Hydrodynamically actuated preservative free dispensing system
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Also Published As

Publication number Publication date
DE19823719B4 (de) 2011-12-15
US7105357B1 (en) 2006-09-12
WO1999061881A2 (de) 1999-12-02
DE19823719A1 (de) 1999-12-16
EP1082594A2 (de) 2001-03-14

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