WO1999055397A1 - Implants de renfort pour sutures tissulaires - Google Patents

Implants de renfort pour sutures tissulaires Download PDF

Info

Publication number
WO1999055397A1
WO1999055397A1 PCT/FR1999/000934 FR9900934W WO9955397A1 WO 1999055397 A1 WO1999055397 A1 WO 1999055397A1 FR 9900934 W FR9900934 W FR 9900934W WO 9955397 A1 WO9955397 A1 WO 9955397A1
Authority
WO
WIPO (PCT)
Prior art keywords
tissue
implant
reinforcement implant
tissue sutures
sutures according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/FR1999/000934
Other languages
English (en)
French (fr)
Inventor
Fabrice Thevenet
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to AT99915803T priority Critical patent/ATE209932T1/de
Priority to AU34251/99A priority patent/AU743763B2/en
Priority to US09/674,275 priority patent/US6962594B1/en
Priority to JP2000545593A priority patent/JP2002512857A/ja
Priority to EP99915803A priority patent/EP1075289B1/fr
Priority to CA002330491A priority patent/CA2330491C/fr
Priority to DE69900556T priority patent/DE69900556T2/de
Publication of WO1999055397A1 publication Critical patent/WO1999055397A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/148—Materials at least partially resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/042—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/068—Surgical staplers, e.g. containing multiple staples or clamps
    • A61B17/072—Surgical staplers, e.g. containing multiple staples or clamps for applying a row of staples in a single action, e.g. the staples being applied simultaneously
    • A61B17/07292—Reinforcements for staple line, e.g. pledgets

Definitions

  • the invention relates to an implant intended to provide mechanical reinforcement, in particular at the level of tissue sutures, manual or mechanical.
  • this actuation also induces the sectioning of the member and of the sleeve, so that only a part of said sleeve remains at the level of the residual member, acting as suture reinforcement of the type splint.
  • splints can serve as a vector for the transmission of viruses or prions and therefore prove to be dangerous. Furthermore, such splints are also not bio-absorbable.
  • the object of the invention is to provide implants for reinforcing tissue sutures, which have both bio-resorption, elasticity and malleability properties which allow perfect adaptation to the tissue support and optimize gas tightness. and / or blood sutures, and this at a reasonable cost price.
  • the object of the invention is also to provide an implant which is completely harmless, after sterilization, concerning the transmission of viruses or prions.
  • Another object of the invention is to propose a reinforcing implant for tissue sutures capable of promoting the healing of the tissues thus protected, with the aim of reducing the durations of drainage, of hospitalization, therefore the costs, and of not constituting an aggravating factor in case of infection.
  • This absorbable implant makes it possible to obtain a reduction in the inflammatory reaction.
  • the invention also aims to propose a reinforcement implant for tissue sutures, capable of exhibiting a certain seal, in particular with respect to air and biological fluids (blood, lymph, digestive juices) at the level of the organs thus sutured.
  • This implant for reinforcing tissue sutures intended to be used to mechanically reinforce the sutured tissue areas is characterized in that it consists of a textile sheet produced from polyuronic acid or its salts.
  • This textile, fibrous or filamentary web can be of the woven, knitted or non-woven type.
  • polyuronic acid [C 6 H g 0 6 " ] n is used directly, in the form of oxidized cellulose obtained from plants (plants, wood), or in the form of alginate of calcium, that is to say calcium salts of polyuronic acid [C 6 H 8 0 6 " ] n Ca 2+ m .
  • this calcium alginate is obtained from algae.
  • Textilization of calcium alginate a fibrous, nonwoven web is produced in the following manner.
  • a load-weighing machine made of calcium alginate fibers of determined length is loaded, said loader supplying a card.
  • a veil is obtained at the outlet of the card, which is folded several times on itself, in order to form a mat, the cohesion of which is ensured by needling, interlacing or even by jet of fluid.
  • a non-woven felt of relatively high density is obtained, capable of giving the implant high mechanical strength in order to fulfill its function of reinforcing sutures.
  • this density is not too high so as to give the implant elasticity and malleability such that it results in perfect adaptation to the tissue support and, as a corollary, to blood and gas tightness. optimum sought.
  • Texturing of the cellulose calls for knitting, which offers similar mechanical properties. It then undergoes a chemical oxidation treatment. 4
  • This felt or knitted fabric can be used in flat splints, cut on demand to the desired dimensions.
  • they are of such flexibility that they can be in the form of sheaths or sleeves, suitable for being put in place by simple sliding at the level of the two branches of a clamp for suturing of a type. known per se, and as marketed for example under the registered trademark SEAMGUARD by WLGore & Associates, Inc., or also under the registered trademark PERIPATCH by Mitroflow International, Inc ..
  • the implants thus obtained are sealed by impregnation, and in particular by soaking in an aqueous solution of a polyuronic acid ester or of its salts, and for example of a solution of sodium alginate ester at 3%.
  • This aqueous solution of sodium alginate ester is produced on the basis of Propylene Glycol Alginate, available in the pharmacopoeia.
  • said implants are dried in a sterile atmosphere.
  • suture reinforcement implants are very particularly indicated for tissue sutures, especially pulmonary sutures in the context of lobar pulmonary exeresis, in the context of pulmonary volume reduction surgery, pulmonary emphysema surgery, pneumothorax, segmental and atypical resections (WEDGES), resections of pulmonary bubbles. In all these cases, gas and blood tightness is required.
  • woven, knitted or non-woven structure also allows a manufacturing conformation adapted to each of the models of mechanical staplers available on the market, including those used in video-surgery or laparoscopic surgery.
  • one or two sleeves are necessary (anvil and clip loader or anvil or charger isolated).
  • the material used is both biocompatible and absorbable in a typical period of three months.
  • the implant is completely harmless, both with regard to viruses and with regard to prions, thereby giving it high safety in use.

Landscapes

  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
PCT/FR1999/000934 1998-04-29 1999-04-20 Implants de renfort pour sutures tissulaires Ceased WO1999055397A1 (fr)

Priority Applications (7)

Application Number Priority Date Filing Date Title
AT99915803T ATE209932T1 (de) 1998-04-29 1999-04-20 Verstärkungsimplantat für gewebeähnliche nähfaden
AU34251/99A AU743763B2 (en) 1998-04-29 1999-04-20 Reinforcing implants for tissue sutures
US09/674,275 US6962594B1 (en) 1998-04-29 1999-04-20 Reinforcement implants for tissue sutures
JP2000545593A JP2002512857A (ja) 1998-04-29 1999-04-20 組織縫合向けの補強用インプラント
EP99915803A EP1075289B1 (fr) 1998-04-29 1999-04-20 Implants de renfort pour sutures tissulaires
CA002330491A CA2330491C (fr) 1998-04-29 1999-04-20 Implants de renfort pour sutures tissulaires
DE69900556T DE69900556T2 (de) 1998-04-29 1999-04-20 Verstärkungsimplantat für gewebeähnliche nähfaden

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9805688A FR2778081B1 (fr) 1998-04-29 1998-04-29 Implants de renfort pour sutures tissulaires
FR98/05688 1998-04-29

Publications (1)

Publication Number Publication Date
WO1999055397A1 true WO1999055397A1 (fr) 1999-11-04

Family

ID=9526061

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR1999/000934 Ceased WO1999055397A1 (fr) 1998-04-29 1999-04-20 Implants de renfort pour sutures tissulaires

Country Status (11)

Country Link
US (1) US6962594B1 (enExample)
EP (1) EP1075289B1 (enExample)
JP (1) JP2002512857A (enExample)
AT (1) ATE209932T1 (enExample)
AU (1) AU743763B2 (enExample)
CA (1) CA2330491C (enExample)
DE (1) DE69900556T2 (enExample)
ES (1) ES2168862T3 (enExample)
FR (1) FR2778081B1 (enExample)
PT (1) PT1075289E (enExample)
WO (1) WO1999055397A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2850281A1 (fr) * 2003-01-27 2004-07-30 Brothier Lab Procede de fabrication d'un dispositif de renfort de suture

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Also Published As

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ATE209932T1 (de) 2001-12-15
EP1075289B1 (fr) 2001-12-05
ES2168862T3 (es) 2002-06-16
FR2778081B1 (fr) 2000-08-25
CA2330491C (fr) 2005-11-15
US6962594B1 (en) 2005-11-08
AU743763B2 (en) 2002-02-07
JP2002512857A (ja) 2002-05-08
EP1075289A1 (fr) 2001-02-14
CA2330491A1 (fr) 1999-11-04
AU3425199A (en) 1999-11-16
DE69900556T2 (de) 2002-08-22
FR2778081A1 (fr) 1999-11-05
PT1075289E (pt) 2002-05-31
DE69900556D1 (de) 2002-01-17

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