WO1995000101A1 - Recipient a usage medical - Google Patents

Recipient a usage medical Download PDF

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Publication number
WO1995000101A1
WO1995000101A1 PCT/JP1994/000935 JP9400935W WO9500101A1 WO 1995000101 A1 WO1995000101 A1 WO 1995000101A1 JP 9400935 W JP9400935 W JP 9400935W WO 9500101 A1 WO9500101 A1 WO 9500101A1
Authority
WO
WIPO (PCT)
Prior art keywords
case
drug vial
fixing jig
state
vial
Prior art date
Application number
PCT/JP1994/000935
Other languages
English (en)
Japanese (ja)
Inventor
Kouji Umekita
Yoshihide Miyake
Original Assignee
Roussel Morishita Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Morishita Co., Ltd. filed Critical Roussel Morishita Co., Ltd.
Priority to JP50264195A priority Critical patent/JP3493198B2/ja
Publication of WO1995000101A1 publication Critical patent/WO1995000101A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2089—Containers or vials which are to be joined to each other in order to mix their contents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/1462—Containers with provisions for hanging, e.g. integral adaptations of the container
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006—Piercing means
    • A61J1/201—Piercing means having one piercing end
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006—Piercing means
    • A61J1/2013—Piercing means having two piercing ends
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2048—Connecting means
    • A61J1/2051—Connecting means having tap means, e.g. tap means activated by sliding
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2048—Connecting means
    • A61J1/2065—Connecting means having aligning and guiding means

Definitions

  • the present invention relates to a medical container capable of dissolving a solid drug such as a powdered drug or a freeze-dried drug in a dissolving solution such as a saline solution or an aqueous glucose solution in a sealed container at the time of use to prepare an injection and instilling the solution. It is about. Background art
  • Some antibiotics and blood products are supplied to medicine as solid preparations due to problems of pharmaceutical stability, and are dissolved immediately before use and administered intravenously as injections.
  • the drug dissolving operation has conventionally been performed by mutually connecting the drug vial and the dissolving solution container each sealed with a rubber stopper with a hollow double-ended needle having cutting edges at both ends. If such a communicating operation is performed in a state where the rubber stoppers and the hollow double-ended needles of both containers are exposed to the outside air, there is a risk that the medicine is contaminated.
  • Japanese Patent Application Publication No. Sho 61-501112 discloses that a capsule containing a drug vial and a flexible dissolving solution container are connected by a conduit means, and the conduit means is provided with a communicating means. Medical containers are disclosed. Also, Japanese Patent Application Laid-Open No. 2-12777 discloses a medical container in which a communication mechanism is improved so that the communication operation can be performed easily and reliably.
  • the medical container disclosed in the above-cited Japanese Patent Publication No. Sho 61-501119 has a problem that the communication operation is troublesome.
  • the medical container disclosed in the above-mentioned Japanese Patent Application Laid-Open No. 2-12777 has been considerably improved with respect to the simplification of the communication operation, the communication is performed by rotating the cap. It is difficult to say that it has the simplicity that is suitable for emergency medical situations that require the administration of various drugs.
  • the medical container since the medical container has a long overall length and a large number of parts constituting the container, it is suitable for a medical site where the storage space for the drug is narrow and the disposal of used medical equipment requires a lot of expense. Hard to say.
  • the overall length of the medical container is too long, the head between the medical container and the drip administration site will decrease, and the infusion pressure into the vein will decrease. The blood may flow back and cannot be infused. Therefore, it is necessary to make the overall length of the medical container as short as possible in order not to hinder drip due to natural fall.
  • An object of the present invention is to enable rapid communication between a drug vial and a dissolving solution container while maintaining a sealed system, so that a sterile drug dissolving operation can be quickly performed during infusion treatment, and furthermore, storage space
  • a medical container capable of reducing the number of parts and shortening the overall length without taking any steps.
  • the present invention has a closed connection port, a sealed solution container, and a bottomed cylindrical shape having a connection pipe connected to the connection port at the bottom.
  • a case an opening provided in the bottom, a fixing jig held in the case movably in the axial direction, and an opening sealed with a stopper made of an elastic material inside the bottom of the fixing jig.
  • the present invention is characterized in that the mouth portion is formed by fixing an annular cap on the outer side of the stopper so as to prevent the stopper from coming off, and an annular cap is provided between the bottom of the fixing jig and the cap.
  • the elastic member was interposed, and the upper part of the top opening of the cap was bent toward the plug, and the cap was air-tightly pressed to the top surface of the cap.
  • the present invention relates to a state where the medicine vial is attached to the case in a state of being in contact with the bottom of the medicine vial fitted in the case, and is not separated from the bottom without destroying the attached portion.
  • a hanger attached to the case was provided.
  • FIG. 1 is a perspective view of a medical container according to a first embodiment of the present invention.
  • FIG. 2 is an exploded perspective view of the medical container shown in FIG.
  • FIG. 3 is a longitudinal sectional view of a drug vial fixing jig in the medical container shown in FIG.
  • FIG. 4 is a longitudinal sectional view of a double-ended needle in the medical container shown in FIG. 1.
  • FIG. 5 is a longitudinal sectional view of a case in the medical container shown in FIG.
  • FIG. 6 is a sectional view taken along line VI-VI of the medical container shown in FIG.
  • FIG. 7 is a partially broken front view showing a state before a communication operation of the medical container shown in FIG. 1.
  • FIG. 8 is a partially broken front view showing a state immediately after the start of the communication operation of the medical container shown in FIG. 1.
  • FIG. 9 is a partially cutaway front view showing a state at the time of completion of the communication operation of the medical container shown in FIG. 1.
  • FIG. 10 is a partially cutaway front view showing the structure of the medical container according to the second embodiment of the present invention in which the air vent holes of the medical container shown in FIG. 1 are replaced with air vent grooves.
  • FIG. 11 is a partially cutaway front view of a medical container according to a third embodiment of the present invention.
  • FIG. 12 is a partially broken front view of a medical container according to a fourth embodiment of the present invention.
  • FIG. 13 is a partially cutaway front view of a medical container according to a fifth embodiment of the present invention.
  • FIG. 14 is a partially cutaway front view of a medical container according to a sixth embodiment of the present invention.
  • FIG. 15 is a partially cutaway front view of the medical container according to the seventh embodiment of the present invention.
  • FIG. 16 is a partial cross-sectional view showing an example of a state of the medical container shown in FIG. 15 before the hanging tool is attached.
  • FIG. 17 is a partial cross-sectional view showing an example of a state after the hanging device of the medical container shown in FIG. 15 is attached.
  • FIG. 18 is a perspective view showing a state before use of the medical container shown in FIG.
  • FIG. 19 is a perspective view showing a state after use of the medical container shown in FIG. Detailed description of the embodiment
  • FIG. 1 is a perspective view of a medical container according to a first embodiment of the present invention, wherein 1 is a solution container, 2 is a drug vial, 3 is a drug vial fixing jig, and 4 is a bottomed cylindrical case. , 5 indicate a connecting portion.
  • the dissolution liquid container 1 is a flexible container formed of a material such as a thermoplastic polyolefin resin, soft vinylino chloride / resin, or ethylene-vinyl acetate copolymer, and a thin film 3 2 (No. 7) It has a connection port 7 sealed with, and a chemical solution outlet 9 sealed at the bottom with a rubber stopper, and is filled with a solution.
  • the drug vial 2 is a drug-containing container whose mouth is sealed with a rubber stopper.
  • the bottom of the case 4 has a hollow connecting pipe 6 formed integrally with the main body of the case 4.
  • the case 4 has a flange at the upper end thereof, and a hanger 8 and a hanger pivot 10 at the upper part of the outer wall.
  • the hanger 8 is pivotally supported by a hanger pivot 10 provided on the outer wall of the case 4.
  • the connecting part 5 is composed of the connecting pipe 6 and the connecting port part 7 described above, and both are fitted and locked in an airtight manner.
  • the drug vial 2 is placed with its mouth 11 down, and the mouth 11 is in the recess 20 of the drug vial fixing jig 3 (see FIG. 3). Is inserted into.
  • Ring packing 1 2 It is installed in an annular groove 13 formed in the inner wall of the tool 3.
  • the annular packing 12 prevents the airtightness in the case 4 from being impaired due to the variation in the diameter of the body of the drug vial 2 caused by mass production.
  • the annular packing 16 is mounted in an annular groove 14 formed in the outer wall of the body of the drug vial fixing jig 3.
  • the annular packing 17 is mounted in an annular groove 15 formed in a flange portion of the drug vial fixing jig 3. As described above, the drug vial 2 and the drug vial fixing jig 3 are airtightly and movably held by the case 4 via the annular packings 12, 16, and 17. A sealed space is formed between the drug vial fixing jig 3 into which the drug vial 2 is inserted and the bottom of the case 4, and a double-ended needle 18 is installed in the sealed space.
  • the drug vial fixing jig 3 has an opening 21 for passing the blade surface of the double-ended needle 18 at the bottom of the recess 20.
  • the flange portion of the drug vial fixing jig 3 is provided with an air vent hole 22 penetrating vertically.
  • the material of the drug vial fixing jig 3 is preferably a hard plastic or rubber.
  • the annular packings 12, 16, and 17 can be formed integrally with the drug vial fixing jig 3.
  • the material of the annular packings 12, 16, 16 is preferably a soft plastic such as polystyrene, silicon rubber, butadiene rubber, isoprene rubber, or the like. As shown in FIG.
  • the double-ended needle 18 is provided with a hub 23, which keeps the penetration depth constant when the rubber vial mouth rubber stopper 37 (see FIG. 7) is pierced therebetween.
  • the double-ended needle 18 is provided with an engaging portion 24 for engaging an annular groove 26 (see FIG. 2) formed on the inner wall of the case 4 and a liquid leakage preventing portion 25.
  • a metal needle made of stainless steel, a hard plastic resin, or the like is preferable.
  • the case 4 has three annular grooves 26, 27, 28 and a groove 29 for exhaust are formed.
  • the exhaust groove 29 is formed in the axial direction, and is formed between the two annular grooves 27 and 28 on the upper side of the case. Further, as can be seen from the cross-sectional view of FIG. 6, the exhaust grooves 29 are formed so as to face two portions of the inner wall of the case 4 respectively.
  • the connecting tube 6 located at the bottom of the case 4 has a through hole 31 into which the connecting portion rubber plug 19 (see FIG. 2) is fitted and a connecting portion fitting projection 3 8 of the solution container 1 (see FIG. 7). ) Is provided with a fitting groove 30 into which the fits.
  • the medicine vial fixing jig 3 in which the medicine vial 2 is fitted is a state in which the annular packing 16 is in close contact with the annular groove 28 and the annular packing 17 is in close contact with the annular groove 27. , Placed in case 4.
  • the drug vial fixing jig 3 has a flange portion below the jig, and a flange portion including an outer flange portion 33 and an inner flange portion 34 at an upper end portion. Further, the drug vial fixing jig 3 is provided with a convex portion 36 and at least two notches 35 on its body side wall. As described above, the drug vial fixing jig into which the drug vial 2 is inserted is provided.
  • annular packings 12 and 16 prevent the outside air from entering the above-mentioned closed space, and assure sterility in the closed space.
  • the two annular packings 16 and 17 fit into the annular grooves 27 and 28, respectively, so that the vibration via the transportation etc. occurs during transportation. Variations in position are avoided.
  • FIG. 8 shows a state immediately after the communication operation between the drug vial 2 and the solution container 1 is started
  • FIG. 9 shows a state after the communication operation is completed.
  • Soluble with drug vial 2 In order to communicate the lysis solution 1, first, the bottom of the drug vial 2 is pressed downward. More specifically, the bottom surface of the drug vial 2 is pressed down with a finger, and the drug vial fixing jig 3 is lowered toward the dissolution liquid container 1. By this operation, the two annular packings 16 and 17 come off the annular grooves 27 and 28. While the annular packing 16 is disengaged from the annular groove 28 and descends toward the bottom of the case 4, it slides inside the case 4 without closing the exhaust groove 29.
  • the annular packing 16 slides in the case 4 without closing the exhaust groove 29, so that the inside of the closed space in the case 4 is reduced by the lowering of the drug vial fixing jig 3.
  • the air is discharged from the case 4 through the exhaust groove 29 through the air vent hole 22.
  • the drug vial fixing jig 3 holding the drug vial 2 can be easily lowered without being pushed back by the air in the reduced closed space.
  • the tip of the locking portion 24 of the double-ended needle 18 is disengaged from the annular groove 26, and the double-ended needle 18 is lowered toward the solution container 1. As a result, as shown in FIG.
  • the connecting part rubber stopper 19 of the connecting part 5 and the thin film 32 and the medicine vial mouth rubber stopper 37 on the opposite side are instantaneously stimulated by the double-ended needle 18. .
  • the annular packing 16 is fitted into the annular groove 27, and a closed space is formed again between the medicine vial fixing jig 3 and the bottom of the case 4.
  • the annular packing 16 fits into the annular groove 27, and the annular packing 17 fits into the annular groove 26, thereby preventing the vial fixing jig 3 from floating.
  • the air vent hole 22 can be replaced with an air vent groove 39 having the same shape as the exhaust groove 29.
  • the drug vial 2 and the dissolution liquid container 1 are communicated with each other, the force for leveling them, the lifting of the dissolution liquid container 1 above the drug vial 2, the pressing of the wall surface, and the dissolving liquid in the drug vial 2 To dissolve the drug.
  • the solution is returned to the dissolution solution container 1, the hanging device 8 is hung on the hook of the infusion stand, the infusion set is attached to the solution outlet 9 of the solution solution container 1, and the patient is infused. Inject intravenously.
  • the drug vial fixing jig 3 can be taken out of the case 4 by pulling up the outer flange 33 provided at the upper end of the drug vial fixing jig 3. Takataka who took out the drug vial fixing jig 3 picks up the drug vial 2 inserted into the drug vial fixing jig 3 with his finger on the side wall of the drug vial 2 exposed from the cutout portion 3 5 and pulls it up. Can be taken out. As described above, this medical container has a feature that it can be easily separated and discarded after use.
  • FIG. 11 shows a medical container according to a third embodiment of the present invention.
  • the exhaust groove 29 formed on the inner wall of the case 4 in the previous embodiment is formed on the outer wall of the body of the drug vial fixing jig 3.
  • the annular packing mounted on the outer wall of the body of the drug vial fixing jig 3 is mounted on the inner wall of the case 4.
  • the hanging member 8 is not shown, but in the second and third embodiments, the hanging member 8 is provided as in the first embodiment.
  • Dissolution solution container bottomed cylindrical case, drug vial with its mouth down, cylindrical drug vial fixing jig, hollow double-ended needle, exhaust groove, and exhaust And a shielding body that slides in the case without closing the groove, so that the medicine vial and the solution container can be aseptically and quickly communicated by a simple operation of pressing the medicine vial.
  • the dissolution operation of the drug can be performed quickly.
  • the drug vial is held in a state of being pushed into the case when the dissolved drug is infused, so that the total length of the container is short, and the medical container is And the drop between the infusion administration sites can be made sufficiently large.
  • the number of parts is small and the shape of the egg is small, so that there is an effect that the used waste is small and the waste can be easily separated and discarded.
  • FIG. 12 shows a medical container according to a fourth embodiment of the present invention.
  • the medical container according to the first embodiment includes the mouth of the drug vial 2 and the drug vial fixing jig 3. Except for the bottom part, the other parts are substantially the same, and the common parts are denoted by the same reference numerals and description thereof is omitted.
  • annular cap 41 is fixed to the outside of an elastic material sealing the mouth of the drug vial 2, for example, a rubber stopper 37a, and the top surface of the stopper 37a is fixed.
  • the outer periphery of the neck of the drug vial 2 is wound around with an annular cap 41, and the stopper 37a is prevented from falling out of the mouth to ensure the hermeticity of the drug vial 2.
  • An annular elastic member 42 having an L-shaped cross section is interposed between the bottom of the drug vial fixing jig 3 and the cap 41, and the drug vial above the cap 41 is fixed in FIG. The space inside the jig 3 and the opening at the bottom of the drug vial fixing jig 3 are completely shut off.
  • the edge of the opening at the top of the cap 41 is bent toward the stopper 37a side, and is pressed against the top of the 37a in an airtight manner, and the inner peripheral surface of the cap 41 and the drug vial are formed.
  • the opening at the bottom of the fixture 3 is completely shut off.
  • the cap 41 Even if bacteria exist between the stopper and the stopper 37a and this bacteria comes out of the space inside the drug vial fixing jig 3 above the cap 41, the bacteria may It is prevented from coming out to the bottom opening side. Also, the edge of the opening of the top surface of the cap 41 is bent toward the stopper 37a side, and the cap 41 is tightly pressed against the top surface of the stopper 37a to form the cap 41 and the stopper 37a. Even if bacteria exist between the two, this bacteria is prevented from coming out to the open side of the drug vial fixing jig 3. As a result, the sterility of the space accommodating the double-ended needle 18 can be more reliably assured.
  • FIG. 13 shows a medical container according to a fifth embodiment of the present invention.
  • the medical container according to the fourth embodiment is provided with an elastic member 42 a instead of the elastic member 42. Except for this point, the other parts are substantially the same, and the common parts are denoted by the same reference numerals and description thereof is omitted.
  • FIG. 14 shows a medical container according to a sixth embodiment of the present invention.
  • the medical container according to the fourth embodiment is different from the medical container according to the fourth embodiment in that an elastic member 42 b is provided instead of the elastic member 42. Except for this point, the other parts are substantially the same, and the common parts are denoted by the same reference numerals and description thereof is omitted.
  • the elastic member 42b having an opening at the center of the disk is used. Then, by forming them as in the fifth and sixth embodiments, the same effects as in the case of the fourth embodiment can be obtained. That is, in addition to the effects of the first to third embodiments, even if bacteria exist between the cap 4.1 and the stopper 37a, the bacteria emerge at the opening side of the drug vial fixing jig 3. In this way, the space containing the double-ended needle 18 is more reliably assured of sterility.
  • the air vent groove 39 in the second embodiment may be provided instead of the air vent hole 22. Further, the exhaust groove 29 is provided not on the inner surface of the case 4. Alternatively, it may be provided on the outer periphery of the drug vial fixing jig 3 as in the third embodiment.
  • hanging members 8 are not shown in FIGS. 12, 13, and 14, the hanging members 8 are provided in the fourth, fifth, and sixth embodiments, similarly to the first embodiment. ing.
  • FIGS. 15 to 19 show a medical container according to a seventh embodiment of the present invention.
  • the medical container according to the fifth embodiment uses a case 51 instead of the case 4. Except for the point and the point that the hanging tool 52 is used instead of the hanging tool 8, the others are substantially the same, and the common parts are denoted by the same reference numerals and the description is omitted.
  • the hanging tool 52 is attached to the case 51 in a state of being in contact with the bottom of the drug vial 2 fitted in the drug vial fixing jig 3, and the mounting portion 53 is provided with the hanging tool 5. Once 2 is removed from case 51, it cannot be returned to its original state.
  • the projecting portion 54 formed in the case 51 is fitted into a through hole 55 formed at the lower end of the hanging tool 52, and then the projecting portion 54 is formed.
  • the head is pressed so as to be larger than the inner diameter of the through-hole 55 to expand in the radial direction. Then, by attaching the suspenders 52 in this manner, Therefore, it is possible to avoid a problem that occurs when the medicine vial 2 and the medicine vial fixing jig 3 fitted in the case 51 are taken out of the case 51 before the use of the medicine vial 2.
  • the hanging tool 52 prevents the medicine vial 2 and the medicine vial fixing jig 3 before use from being taken out without breaking the hanging tool 52 and the mounting portion 53 thereof. As a result, it is possible to maintain the sterility of the closed space in the case 51.
  • the hanging tool 52 prevents the medicine vial 2 in the medicine vial fixing jig 3 from being accidentally replaced with another medicine vial.
  • the hanging member 52 is a square formed by the four corners of the four inner peripheral surfaces of the opposed inner flange portion 34. It is good to be attached so that two corners located on the diagonal line of abutment may be contacted. With such a structure, before using the drug vial 2, even if the hanging tool 52 is tilted sideways so as to separate from the bottom of the drug vial 2, the inner flange 34 becomes an obstacle and the hanging tool 52 is tilted. You will not be able to do it.
  • the drug vial 2 and the drug nozzle fixing jig 3 are separated from the hanging tool 52, so that the hanging tool 2 is turned over.
  • the drug noial 2 and the drug vial fixing jig 3 can be taken out of the case 51.
  • Notches are formed in both legs of the hanging tool 52 in advance, and after using the medical container, the hanging tool 52 is bent at the notch to remove the drug vial 2 from the case 51. It may be taken out.
  • the air vent groove 39 in the second embodiment may be provided in place of the air vent hole 22.
  • the exhaust groove 29 is provided not on the inner surface of the case 51 but on the third surface. It may be provided on the outer periphery of the medicine vial fixing jig 3 as in the embodiment.
  • the elastic member 42 or 42b may be used instead of the elastic member 42a.

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

Récipient à usage médical permettant de réaliser rapidement un flacon à médicament et un récipient à solution communiquant l'une avec l'autre grâce à un système restant étanche, ce qui permet d'exécuter rapidement une opération de dissolution de médicament en condition d'aseptie dans le cadre d'un traitement par instillation. Ce récipient est peu encombrant, compte un petit nombre de composants et occupe une longueur totale réduite. Pour parvenir à cette fin, ce récipient comporte un récipient à solution, une enveloppe cylindrique à fond, un élément de fixation comportant une ouverture à sa partie inférieure, maintenu dans l'enveloppe de manière à pouvoir être déplacé selon le sens axial, un flacon à médicament maintenu dans l'enveloppe de manière à pouvoir se déplacer avec l'élément de fixation, une aiguille creuse à deux extrémités maintenue mobile dans un espace étanche réalisé du côté du fond de l'enveloppe d'une embouchure du flacon, de rainures de libération d'air menagées sur la face interne de l'enveloppe ou sur la face externe de l'élément de fixation, et un écran conçu pour assurer l'étanchéité à l'air de l'espace confiné tant que le flacon à médicament n'est pas engagé à force dans l'enveloppe, et pour se déplacer en coulissant dans l'enveloppe sans obturer les rainures de libération d'air tandis que le flacon est engagé à force dans l'enveloppe et avance vers la partie inférieure de celui-ci.
PCT/JP1994/000935 1993-06-28 1994-06-09 Recipient a usage medical WO1995000101A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP50264195A JP3493198B2 (ja) 1993-06-28 1994-06-09 医療用容器

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP5/40940U 1993-06-28
JP4094093 1993-06-28

Publications (1)

Publication Number Publication Date
WO1995000101A1 true WO1995000101A1 (fr) 1995-01-05

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP1994/000935 WO1995000101A1 (fr) 1993-06-28 1994-06-09 Recipient a usage medical

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JP (1) JP3493198B2 (fr)
WO (1) WO1995000101A1 (fr)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0737467A1 (fr) * 1995-04-11 1996-10-16 BEHRINGWERKE Aktiengesellschaft Dispositif de réunir une première composante liquide et une deuxième composante rigide ou liquide au moyen de vide sous des conditions stériles
WO2011050468A1 (fr) * 2009-10-30 2011-05-05 Duoject Medical Systems Inc. Système de transfert entre récipients
WO2013055392A2 (fr) 2011-10-03 2013-04-18 Hospira, Inc. Système et procédé de mélange du contenu de deux récipients
US9205026B2 (en) 2007-08-01 2015-12-08 Hospira, Inc. Medicament admixing system
JPWO2013175970A1 (ja) * 2012-05-23 2016-01-12 ニプロ株式会社 医療用容器
WO2016177384A1 (fr) * 2015-05-06 2016-11-10 Kocher-Plastik Maschinenbau Gmbh Système de prélèvement de contenu de récipient
WO2016177383A1 (fr) * 2015-05-06 2016-11-10 Kocher-Plastik Maschinenbau Gmbh Système de prélèvement de contenu de récipient
JP2019146955A (ja) * 2018-02-27 2019-09-05 内外化成株式会社 移注部材の使用方法及び薬剤混合キットの使用方法

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JP5095382B2 (ja) * 2007-12-26 2012-12-12 テルモ株式会社 接続具
JP7087798B2 (ja) * 2018-03-09 2022-06-21 ニプロ株式会社 医療用容器
WO2019171883A1 (fr) * 2018-03-09 2019-09-12 ニプロ株式会社 Récipient médical

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Cited By (21)

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US5743312A (en) * 1995-04-11 1998-04-28 Behringwerke Aktiengesellschaft Component mixing apparatus and system including a movable cannula
EP0737467A1 (fr) * 1995-04-11 1996-10-16 BEHRINGWERKE Aktiengesellschaft Dispositif de réunir une première composante liquide et une deuxième composante rigide ou liquide au moyen de vide sous des conditions stériles
US9205026B2 (en) 2007-08-01 2015-12-08 Hospira, Inc. Medicament admixing system
US9205025B2 (en) 2007-08-01 2015-12-08 Hospira, Inc. Medicament admixing system
WO2011050468A1 (fr) * 2009-10-30 2011-05-05 Duoject Medical Systems Inc. Système de transfert entre récipients
AU2017201622B2 (en) * 2011-10-03 2017-12-21 Hospira, Inc. System and method for mixing the contents of two containers
WO2013055392A2 (fr) 2011-10-03 2013-04-18 Hospira, Inc. Système et procédé de mélange du contenu de deux récipients
EP2763619A2 (fr) * 2011-10-03 2014-08-13 Hospira, Inc. Système et procédé de mélange du contenu de deux récipients
EP2763619A4 (fr) * 2011-10-03 2015-04-22 Hospira Inc Système et procédé de mélange du contenu de deux récipients
AU2017201624B2 (en) * 2011-10-03 2017-12-21 Hospira, Inc. System and method for mixing the contents of two containers
AU2012321351B2 (en) * 2011-10-03 2017-04-13 Hospira, Inc. System and method for mixing the contents of two containers
JPWO2013175970A1 (ja) * 2012-05-23 2016-01-12 ニプロ株式会社 医療用容器
WO2016177383A1 (fr) * 2015-05-06 2016-11-10 Kocher-Plastik Maschinenbau Gmbh Système de prélèvement de contenu de récipient
WO2016177384A1 (fr) * 2015-05-06 2016-11-10 Kocher-Plastik Maschinenbau Gmbh Système de prélèvement de contenu de récipient
CN107567325A (zh) * 2015-05-06 2018-01-09 科赫尔塑料机械制造有限公司 容器‑提取系统
JP2018521709A (ja) * 2015-05-06 2018-08-09 コッヒャー−プラスティック マシーネンバウ ゲゼルシャフト ミット ベシュレンクテル ハフツング 容器移動システム
RU2702333C2 (ru) * 2015-05-06 2019-10-08 Кохер-Пластик Машиненбау Гмбх Система перемещения содержимого контейнеров
US10675219B2 (en) 2015-05-06 2020-06-09 Kocher-Plastik Maschinenbau Gmbh Transfer system for containers
US10932990B2 (en) 2015-05-06 2021-03-02 Kocher-Plastik Maschinenbau Gmbh Transfer system for containers
JP2019146955A (ja) * 2018-02-27 2019-09-05 内外化成株式会社 移注部材の使用方法及び薬剤混合キットの使用方法
JP7235286B2 (ja) 2018-02-27 2023-03-08 内外化成株式会社 移注部材及び薬剤混合キット

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