WO1995000101A1 - Medical container - Google Patents

Medical container Download PDF

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Publication number
WO1995000101A1
WO1995000101A1 PCT/JP1994/000935 JP9400935W WO9500101A1 WO 1995000101 A1 WO1995000101 A1 WO 1995000101A1 JP 9400935 W JP9400935 W JP 9400935W WO 9500101 A1 WO9500101 A1 WO 9500101A1
Authority
WO
WIPO (PCT)
Prior art keywords
case
drug vial
fixing jig
state
vial
Prior art date
Application number
PCT/JP1994/000935
Other languages
French (fr)
Japanese (ja)
Inventor
Kouji Umekita
Yoshihide Miyake
Original Assignee
Roussel Morishita Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Morishita Co., Ltd. filed Critical Roussel Morishita Co., Ltd.
Priority to JP50264195A priority Critical patent/JP3493198B2/en
Publication of WO1995000101A1 publication Critical patent/WO1995000101A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/20Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2089Containers or vials which are to be joined to each other in order to mix their contents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/1462Containers with provisions for hanging, e.g. integral adaptations of the container
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/20Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006Piercing means
    • A61J1/201Piercing means having one piercing end
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/20Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006Piercing means
    • A61J1/2013Piercing means having two piercing ends
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/20Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2048Connecting means
    • A61J1/2051Connecting means having tap means, e.g. tap means activated by sliding
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/20Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2048Connecting means
    • A61J1/2065Connecting means having aligning and guiding means

Definitions

  • the present invention relates to a medical container capable of dissolving a solid drug such as a powdered drug or a freeze-dried drug in a dissolving solution such as a saline solution or an aqueous glucose solution in a sealed container at the time of use to prepare an injection and instilling the solution. It is about. Background art
  • Some antibiotics and blood products are supplied to medicine as solid preparations due to problems of pharmaceutical stability, and are dissolved immediately before use and administered intravenously as injections.
  • the drug dissolving operation has conventionally been performed by mutually connecting the drug vial and the dissolving solution container each sealed with a rubber stopper with a hollow double-ended needle having cutting edges at both ends. If such a communicating operation is performed in a state where the rubber stoppers and the hollow double-ended needles of both containers are exposed to the outside air, there is a risk that the medicine is contaminated.
  • Japanese Patent Application Publication No. Sho 61-501112 discloses that a capsule containing a drug vial and a flexible dissolving solution container are connected by a conduit means, and the conduit means is provided with a communicating means. Medical containers are disclosed. Also, Japanese Patent Application Laid-Open No. 2-12777 discloses a medical container in which a communication mechanism is improved so that the communication operation can be performed easily and reliably.
  • the medical container disclosed in the above-cited Japanese Patent Publication No. Sho 61-501119 has a problem that the communication operation is troublesome.
  • the medical container disclosed in the above-mentioned Japanese Patent Application Laid-Open No. 2-12777 has been considerably improved with respect to the simplification of the communication operation, the communication is performed by rotating the cap. It is difficult to say that it has the simplicity that is suitable for emergency medical situations that require the administration of various drugs.
  • the medical container since the medical container has a long overall length and a large number of parts constituting the container, it is suitable for a medical site where the storage space for the drug is narrow and the disposal of used medical equipment requires a lot of expense. Hard to say.
  • the overall length of the medical container is too long, the head between the medical container and the drip administration site will decrease, and the infusion pressure into the vein will decrease. The blood may flow back and cannot be infused. Therefore, it is necessary to make the overall length of the medical container as short as possible in order not to hinder drip due to natural fall.
  • An object of the present invention is to enable rapid communication between a drug vial and a dissolving solution container while maintaining a sealed system, so that a sterile drug dissolving operation can be quickly performed during infusion treatment, and furthermore, storage space
  • a medical container capable of reducing the number of parts and shortening the overall length without taking any steps.
  • the present invention has a closed connection port, a sealed solution container, and a bottomed cylindrical shape having a connection pipe connected to the connection port at the bottom.
  • a case an opening provided in the bottom, a fixing jig held in the case movably in the axial direction, and an opening sealed with a stopper made of an elastic material inside the bottom of the fixing jig.
  • the present invention is characterized in that the mouth portion is formed by fixing an annular cap on the outer side of the stopper so as to prevent the stopper from coming off, and an annular cap is provided between the bottom of the fixing jig and the cap.
  • the elastic member was interposed, and the upper part of the top opening of the cap was bent toward the plug, and the cap was air-tightly pressed to the top surface of the cap.
  • the present invention relates to a state where the medicine vial is attached to the case in a state of being in contact with the bottom of the medicine vial fitted in the case, and is not separated from the bottom without destroying the attached portion.
  • a hanger attached to the case was provided.
  • FIG. 1 is a perspective view of a medical container according to a first embodiment of the present invention.
  • FIG. 2 is an exploded perspective view of the medical container shown in FIG.
  • FIG. 3 is a longitudinal sectional view of a drug vial fixing jig in the medical container shown in FIG.
  • FIG. 4 is a longitudinal sectional view of a double-ended needle in the medical container shown in FIG. 1.
  • FIG. 5 is a longitudinal sectional view of a case in the medical container shown in FIG.
  • FIG. 6 is a sectional view taken along line VI-VI of the medical container shown in FIG.
  • FIG. 7 is a partially broken front view showing a state before a communication operation of the medical container shown in FIG. 1.
  • FIG. 8 is a partially broken front view showing a state immediately after the start of the communication operation of the medical container shown in FIG. 1.
  • FIG. 9 is a partially cutaway front view showing a state at the time of completion of the communication operation of the medical container shown in FIG. 1.
  • FIG. 10 is a partially cutaway front view showing the structure of the medical container according to the second embodiment of the present invention in which the air vent holes of the medical container shown in FIG. 1 are replaced with air vent grooves.
  • FIG. 11 is a partially cutaway front view of a medical container according to a third embodiment of the present invention.
  • FIG. 12 is a partially broken front view of a medical container according to a fourth embodiment of the present invention.
  • FIG. 13 is a partially cutaway front view of a medical container according to a fifth embodiment of the present invention.
  • FIG. 14 is a partially cutaway front view of a medical container according to a sixth embodiment of the present invention.
  • FIG. 15 is a partially cutaway front view of the medical container according to the seventh embodiment of the present invention.
  • FIG. 16 is a partial cross-sectional view showing an example of a state of the medical container shown in FIG. 15 before the hanging tool is attached.
  • FIG. 17 is a partial cross-sectional view showing an example of a state after the hanging device of the medical container shown in FIG. 15 is attached.
  • FIG. 18 is a perspective view showing a state before use of the medical container shown in FIG.
  • FIG. 19 is a perspective view showing a state after use of the medical container shown in FIG. Detailed description of the embodiment
  • FIG. 1 is a perspective view of a medical container according to a first embodiment of the present invention, wherein 1 is a solution container, 2 is a drug vial, 3 is a drug vial fixing jig, and 4 is a bottomed cylindrical case. , 5 indicate a connecting portion.
  • the dissolution liquid container 1 is a flexible container formed of a material such as a thermoplastic polyolefin resin, soft vinylino chloride / resin, or ethylene-vinyl acetate copolymer, and a thin film 3 2 (No. 7) It has a connection port 7 sealed with, and a chemical solution outlet 9 sealed at the bottom with a rubber stopper, and is filled with a solution.
  • the drug vial 2 is a drug-containing container whose mouth is sealed with a rubber stopper.
  • the bottom of the case 4 has a hollow connecting pipe 6 formed integrally with the main body of the case 4.
  • the case 4 has a flange at the upper end thereof, and a hanger 8 and a hanger pivot 10 at the upper part of the outer wall.
  • the hanger 8 is pivotally supported by a hanger pivot 10 provided on the outer wall of the case 4.
  • the connecting part 5 is composed of the connecting pipe 6 and the connecting port part 7 described above, and both are fitted and locked in an airtight manner.
  • the drug vial 2 is placed with its mouth 11 down, and the mouth 11 is in the recess 20 of the drug vial fixing jig 3 (see FIG. 3). Is inserted into.
  • Ring packing 1 2 It is installed in an annular groove 13 formed in the inner wall of the tool 3.
  • the annular packing 12 prevents the airtightness in the case 4 from being impaired due to the variation in the diameter of the body of the drug vial 2 caused by mass production.
  • the annular packing 16 is mounted in an annular groove 14 formed in the outer wall of the body of the drug vial fixing jig 3.
  • the annular packing 17 is mounted in an annular groove 15 formed in a flange portion of the drug vial fixing jig 3. As described above, the drug vial 2 and the drug vial fixing jig 3 are airtightly and movably held by the case 4 via the annular packings 12, 16, and 17. A sealed space is formed between the drug vial fixing jig 3 into which the drug vial 2 is inserted and the bottom of the case 4, and a double-ended needle 18 is installed in the sealed space.
  • the drug vial fixing jig 3 has an opening 21 for passing the blade surface of the double-ended needle 18 at the bottom of the recess 20.
  • the flange portion of the drug vial fixing jig 3 is provided with an air vent hole 22 penetrating vertically.
  • the material of the drug vial fixing jig 3 is preferably a hard plastic or rubber.
  • the annular packings 12, 16, and 17 can be formed integrally with the drug vial fixing jig 3.
  • the material of the annular packings 12, 16, 16 is preferably a soft plastic such as polystyrene, silicon rubber, butadiene rubber, isoprene rubber, or the like. As shown in FIG.
  • the double-ended needle 18 is provided with a hub 23, which keeps the penetration depth constant when the rubber vial mouth rubber stopper 37 (see FIG. 7) is pierced therebetween.
  • the double-ended needle 18 is provided with an engaging portion 24 for engaging an annular groove 26 (see FIG. 2) formed on the inner wall of the case 4 and a liquid leakage preventing portion 25.
  • a metal needle made of stainless steel, a hard plastic resin, or the like is preferable.
  • the case 4 has three annular grooves 26, 27, 28 and a groove 29 for exhaust are formed.
  • the exhaust groove 29 is formed in the axial direction, and is formed between the two annular grooves 27 and 28 on the upper side of the case. Further, as can be seen from the cross-sectional view of FIG. 6, the exhaust grooves 29 are formed so as to face two portions of the inner wall of the case 4 respectively.
  • the connecting tube 6 located at the bottom of the case 4 has a through hole 31 into which the connecting portion rubber plug 19 (see FIG. 2) is fitted and a connecting portion fitting projection 3 8 of the solution container 1 (see FIG. 7). ) Is provided with a fitting groove 30 into which the fits.
  • the medicine vial fixing jig 3 in which the medicine vial 2 is fitted is a state in which the annular packing 16 is in close contact with the annular groove 28 and the annular packing 17 is in close contact with the annular groove 27. , Placed in case 4.
  • the drug vial fixing jig 3 has a flange portion below the jig, and a flange portion including an outer flange portion 33 and an inner flange portion 34 at an upper end portion. Further, the drug vial fixing jig 3 is provided with a convex portion 36 and at least two notches 35 on its body side wall. As described above, the drug vial fixing jig into which the drug vial 2 is inserted is provided.
  • annular packings 12 and 16 prevent the outside air from entering the above-mentioned closed space, and assure sterility in the closed space.
  • the two annular packings 16 and 17 fit into the annular grooves 27 and 28, respectively, so that the vibration via the transportation etc. occurs during transportation. Variations in position are avoided.
  • FIG. 8 shows a state immediately after the communication operation between the drug vial 2 and the solution container 1 is started
  • FIG. 9 shows a state after the communication operation is completed.
  • Soluble with drug vial 2 In order to communicate the lysis solution 1, first, the bottom of the drug vial 2 is pressed downward. More specifically, the bottom surface of the drug vial 2 is pressed down with a finger, and the drug vial fixing jig 3 is lowered toward the dissolution liquid container 1. By this operation, the two annular packings 16 and 17 come off the annular grooves 27 and 28. While the annular packing 16 is disengaged from the annular groove 28 and descends toward the bottom of the case 4, it slides inside the case 4 without closing the exhaust groove 29.
  • the annular packing 16 slides in the case 4 without closing the exhaust groove 29, so that the inside of the closed space in the case 4 is reduced by the lowering of the drug vial fixing jig 3.
  • the air is discharged from the case 4 through the exhaust groove 29 through the air vent hole 22.
  • the drug vial fixing jig 3 holding the drug vial 2 can be easily lowered without being pushed back by the air in the reduced closed space.
  • the tip of the locking portion 24 of the double-ended needle 18 is disengaged from the annular groove 26, and the double-ended needle 18 is lowered toward the solution container 1. As a result, as shown in FIG.
  • the connecting part rubber stopper 19 of the connecting part 5 and the thin film 32 and the medicine vial mouth rubber stopper 37 on the opposite side are instantaneously stimulated by the double-ended needle 18. .
  • the annular packing 16 is fitted into the annular groove 27, and a closed space is formed again between the medicine vial fixing jig 3 and the bottom of the case 4.
  • the annular packing 16 fits into the annular groove 27, and the annular packing 17 fits into the annular groove 26, thereby preventing the vial fixing jig 3 from floating.
  • the air vent hole 22 can be replaced with an air vent groove 39 having the same shape as the exhaust groove 29.
  • the drug vial 2 and the dissolution liquid container 1 are communicated with each other, the force for leveling them, the lifting of the dissolution liquid container 1 above the drug vial 2, the pressing of the wall surface, and the dissolving liquid in the drug vial 2 To dissolve the drug.
  • the solution is returned to the dissolution solution container 1, the hanging device 8 is hung on the hook of the infusion stand, the infusion set is attached to the solution outlet 9 of the solution solution container 1, and the patient is infused. Inject intravenously.
  • the drug vial fixing jig 3 can be taken out of the case 4 by pulling up the outer flange 33 provided at the upper end of the drug vial fixing jig 3. Takataka who took out the drug vial fixing jig 3 picks up the drug vial 2 inserted into the drug vial fixing jig 3 with his finger on the side wall of the drug vial 2 exposed from the cutout portion 3 5 and pulls it up. Can be taken out. As described above, this medical container has a feature that it can be easily separated and discarded after use.
  • FIG. 11 shows a medical container according to a third embodiment of the present invention.
  • the exhaust groove 29 formed on the inner wall of the case 4 in the previous embodiment is formed on the outer wall of the body of the drug vial fixing jig 3.
  • the annular packing mounted on the outer wall of the body of the drug vial fixing jig 3 is mounted on the inner wall of the case 4.
  • the hanging member 8 is not shown, but in the second and third embodiments, the hanging member 8 is provided as in the first embodiment.
  • Dissolution solution container bottomed cylindrical case, drug vial with its mouth down, cylindrical drug vial fixing jig, hollow double-ended needle, exhaust groove, and exhaust And a shielding body that slides in the case without closing the groove, so that the medicine vial and the solution container can be aseptically and quickly communicated by a simple operation of pressing the medicine vial.
  • the dissolution operation of the drug can be performed quickly.
  • the drug vial is held in a state of being pushed into the case when the dissolved drug is infused, so that the total length of the container is short, and the medical container is And the drop between the infusion administration sites can be made sufficiently large.
  • the number of parts is small and the shape of the egg is small, so that there is an effect that the used waste is small and the waste can be easily separated and discarded.
  • FIG. 12 shows a medical container according to a fourth embodiment of the present invention.
  • the medical container according to the first embodiment includes the mouth of the drug vial 2 and the drug vial fixing jig 3. Except for the bottom part, the other parts are substantially the same, and the common parts are denoted by the same reference numerals and description thereof is omitted.
  • annular cap 41 is fixed to the outside of an elastic material sealing the mouth of the drug vial 2, for example, a rubber stopper 37a, and the top surface of the stopper 37a is fixed.
  • the outer periphery of the neck of the drug vial 2 is wound around with an annular cap 41, and the stopper 37a is prevented from falling out of the mouth to ensure the hermeticity of the drug vial 2.
  • An annular elastic member 42 having an L-shaped cross section is interposed between the bottom of the drug vial fixing jig 3 and the cap 41, and the drug vial above the cap 41 is fixed in FIG. The space inside the jig 3 and the opening at the bottom of the drug vial fixing jig 3 are completely shut off.
  • the edge of the opening at the top of the cap 41 is bent toward the stopper 37a side, and is pressed against the top of the 37a in an airtight manner, and the inner peripheral surface of the cap 41 and the drug vial are formed.
  • the opening at the bottom of the fixture 3 is completely shut off.
  • the cap 41 Even if bacteria exist between the stopper and the stopper 37a and this bacteria comes out of the space inside the drug vial fixing jig 3 above the cap 41, the bacteria may It is prevented from coming out to the bottom opening side. Also, the edge of the opening of the top surface of the cap 41 is bent toward the stopper 37a side, and the cap 41 is tightly pressed against the top surface of the stopper 37a to form the cap 41 and the stopper 37a. Even if bacteria exist between the two, this bacteria is prevented from coming out to the open side of the drug vial fixing jig 3. As a result, the sterility of the space accommodating the double-ended needle 18 can be more reliably assured.
  • FIG. 13 shows a medical container according to a fifth embodiment of the present invention.
  • the medical container according to the fourth embodiment is provided with an elastic member 42 a instead of the elastic member 42. Except for this point, the other parts are substantially the same, and the common parts are denoted by the same reference numerals and description thereof is omitted.
  • FIG. 14 shows a medical container according to a sixth embodiment of the present invention.
  • the medical container according to the fourth embodiment is different from the medical container according to the fourth embodiment in that an elastic member 42 b is provided instead of the elastic member 42. Except for this point, the other parts are substantially the same, and the common parts are denoted by the same reference numerals and description thereof is omitted.
  • the elastic member 42b having an opening at the center of the disk is used. Then, by forming them as in the fifth and sixth embodiments, the same effects as in the case of the fourth embodiment can be obtained. That is, in addition to the effects of the first to third embodiments, even if bacteria exist between the cap 4.1 and the stopper 37a, the bacteria emerge at the opening side of the drug vial fixing jig 3. In this way, the space containing the double-ended needle 18 is more reliably assured of sterility.
  • the air vent groove 39 in the second embodiment may be provided instead of the air vent hole 22. Further, the exhaust groove 29 is provided not on the inner surface of the case 4. Alternatively, it may be provided on the outer periphery of the drug vial fixing jig 3 as in the third embodiment.
  • hanging members 8 are not shown in FIGS. 12, 13, and 14, the hanging members 8 are provided in the fourth, fifth, and sixth embodiments, similarly to the first embodiment. ing.
  • FIGS. 15 to 19 show a medical container according to a seventh embodiment of the present invention.
  • the medical container according to the fifth embodiment uses a case 51 instead of the case 4. Except for the point and the point that the hanging tool 52 is used instead of the hanging tool 8, the others are substantially the same, and the common parts are denoted by the same reference numerals and the description is omitted.
  • the hanging tool 52 is attached to the case 51 in a state of being in contact with the bottom of the drug vial 2 fitted in the drug vial fixing jig 3, and the mounting portion 53 is provided with the hanging tool 5. Once 2 is removed from case 51, it cannot be returned to its original state.
  • the projecting portion 54 formed in the case 51 is fitted into a through hole 55 formed at the lower end of the hanging tool 52, and then the projecting portion 54 is formed.
  • the head is pressed so as to be larger than the inner diameter of the through-hole 55 to expand in the radial direction. Then, by attaching the suspenders 52 in this manner, Therefore, it is possible to avoid a problem that occurs when the medicine vial 2 and the medicine vial fixing jig 3 fitted in the case 51 are taken out of the case 51 before the use of the medicine vial 2.
  • the hanging tool 52 prevents the medicine vial 2 and the medicine vial fixing jig 3 before use from being taken out without breaking the hanging tool 52 and the mounting portion 53 thereof. As a result, it is possible to maintain the sterility of the closed space in the case 51.
  • the hanging tool 52 prevents the medicine vial 2 in the medicine vial fixing jig 3 from being accidentally replaced with another medicine vial.
  • the hanging member 52 is a square formed by the four corners of the four inner peripheral surfaces of the opposed inner flange portion 34. It is good to be attached so that two corners located on the diagonal line of abutment may be contacted. With such a structure, before using the drug vial 2, even if the hanging tool 52 is tilted sideways so as to separate from the bottom of the drug vial 2, the inner flange 34 becomes an obstacle and the hanging tool 52 is tilted. You will not be able to do it.
  • the drug vial 2 and the drug nozzle fixing jig 3 are separated from the hanging tool 52, so that the hanging tool 2 is turned over.
  • the drug noial 2 and the drug vial fixing jig 3 can be taken out of the case 51.
  • Notches are formed in both legs of the hanging tool 52 in advance, and after using the medical container, the hanging tool 52 is bent at the notch to remove the drug vial 2 from the case 51. It may be taken out.
  • the air vent groove 39 in the second embodiment may be provided in place of the air vent hole 22.
  • the exhaust groove 29 is provided not on the inner surface of the case 51 but on the third surface. It may be provided on the outer periphery of the medicine vial fixing jig 3 as in the embodiment.
  • the elastic member 42 or 42b may be used instead of the elastic member 42a.

Abstract

This invention aims at providing a medical container capable of speedily making a drug vial and a solution container communicate with each other with a sealed system kept sealed, and therefore speedily carrying out an aseptic drug dissolving operation during an instillation treatment; not occupying a large storage space; and having a small number of parts and a small total length. To achieve this object, a novel medical container is formed which is provided with a solution container, a bottomed cylindrical case, a fixing jig having an opening at the bottom portion thereof and held in the case so that the jig can be axially moved, a drug vial held in the case so that the vial can be moved with the jig, a hollow double ended needle held movably in a sealed space formed on the case-bottom side of a mouth of the drug vial, air discharge grooves formed in an inner surface of the case or in an outer surface of the fixing jig, and a shield member adapted to maintain air-tight condition of the sealed space until the drug vial is forced into the case, and be slidingly moved in the case without closing the air discharge grooves while the drug vial is forced into the case and moved toward the bottom portion of the same.

Description

明 細 書  Specification
医 療 用 容 器 技術分野  Medical container technology
本発明は、 粉末薬剤や凍結乾燥薬剤のような固体の薬剤を、 用時に密封 系の容器内で生理食塩水ゃブドウ糖水溶液等の溶解液に溶かして注射剤と し、 点滴投与できる医療用容器に関するものである。 背景技術  The present invention relates to a medical container capable of dissolving a solid drug such as a powdered drug or a freeze-dried drug in a dissolving solution such as a saline solution or an aqueous glucose solution in a sealed container at the time of use to prepare an injection and instilling the solution. It is about. Background art
抗生物質や血液製剤の中には、 製剤学的安定性の問題から固体製剤とし て医療に供給され、 使用直前に溶解させて注射剤として経静脈的に投与 ψ れるものがある。 この際の薬剤溶解作業は、 従来より、 それぞれゴム栓で 密封された薬剤バイアルと溶解液容器とを、 両端に刃先を有する中空の両 頭針等で相互に連通させることによって行われていた。 もしも斯る連通操 作が、 両容器のゴム栓と中空の両頭針等が外気に触れた状態で行われるな らば、 薬剤が汚染される危険性がある。  Some antibiotics and blood products are supplied to medicine as solid preparations due to problems of pharmaceutical stability, and are dissolved immediately before use and administered intravenously as injections. Heretofore, the drug dissolving operation has conventionally been performed by mutually connecting the drug vial and the dissolving solution container each sealed with a rubber stopper with a hollow double-ended needle having cutting edges at both ends. If such a communicating operation is performed in a state where the rubber stoppers and the hollow double-ended needles of both containers are exposed to the outside air, there is a risk that the medicine is contaminated.
そこで、 薬剤バイアルと溶解液容器との連通操作を密封系内でできるよ うにした種々の医療用容器が提案されている。 例えば、 特表昭 6 1— 5 0 1 1 2 9号公報には、 薬剤バイアルを収納したカプセルと可撓性の溶解液 容器とが導管手段で連結され、 その導管手段に連通手段が備えられた医療 用容器が開示されている。 また、 特開平 2— 1 2 7 7号公報には、 連通 機構を改良して、 連通操作を簡単かつ確実にできるようにした医療用容器 が開示されている。  Therefore, various medical containers have been proposed in which the communication operation between the drug vial and the solution container can be performed in a sealed system. For example, Japanese Patent Application Publication No. Sho 61-501112 discloses that a capsule containing a drug vial and a flexible dissolving solution container are connected by a conduit means, and the conduit means is provided with a communicating means. Medical containers are disclosed. Also, Japanese Patent Application Laid-Open No. 2-12777 discloses a medical container in which a communication mechanism is improved so that the communication operation can be performed easily and reliably.
前記特表昭 6 1— 5 0 1 1 2 9号公報に開示されている医療用容器は、 連通操作に手間が掛かるという問題を有している。 前記特開平 2— 1 2 7 7号公報に開示されている医療用容器は、 連通操 作の簡略化に関してはかなり改良されているものの、 キャップの回転操作 によって連通を行わ.ねばならず、 迅速な薬剤投与を必要とする緊急医療の 現場に対応した簡便性を有しているとは言い難い。 また、 前記医療用容器 は、 その全長が長く、 容器を構成する部品の数も多いので、 薬剤の保管場 所が狭くまた使用済みの医療用具の廃棄に多くの経費が必要な医療現場に 応えるものとは言い難い。 The medical container disclosed in the above-cited Japanese Patent Publication No. Sho 61-501119 has a problem that the communication operation is troublesome. Although the medical container disclosed in the above-mentioned Japanese Patent Application Laid-Open No. 2-12777 has been considerably improved with respect to the simplification of the communication operation, the communication is performed by rotating the cap. It is difficult to say that it has the simplicity that is suitable for emergency medical situations that require the administration of various drugs. In addition, since the medical container has a long overall length and a large number of parts constituting the container, it is suitable for a medical site where the storage space for the drug is narrow and the disposal of used medical equipment requires a lot of expense. Hard to say.
他方、 医療用容器の全長が長すぎると、 医療用容器と点滴投与部位間の 落差が減少して静脈内への注入圧力が低下し、 極端な例としては、 静脈内 に留置した注射針から血液が逆流して点滴できないことがある。 従って、 自然落下による点滴に支障をきたさないためには、 医療容器の全長をで # る限り短くする必要がある。  On the other hand, if the overall length of the medical container is too long, the head between the medical container and the drip administration site will decrease, and the infusion pressure into the vein will decrease. The blood may flow back and cannot be infused. Therefore, it is necessary to make the overall length of the medical container as short as possible in order not to hinder drip due to natural fall.
本発明の課題は、 密封系を維持した状態で薬剤バイアルと溶解液容器と を迅速に連通させることができ、 点滴治療時に無菌的な薬剤の溶解操作が 速やかに行うことができ、 しかも保管スペースをとらず、 部品数を少なく し、 かつ全長を短くすることを可能とした医療用容器を提供することにあ る o 発明の開示  An object of the present invention is to enable rapid communication between a drug vial and a dissolving solution container while maintaining a sealed system, so that a sterile drug dissolving operation can be quickly performed during infusion treatment, and furthermore, storage space To provide a medical container capable of reducing the number of parts and shortening the overall length without taking any steps.o Disclosure of the invention
前記課題を解決するために、 本発明は、 封止された連結口部を有し、 密 封された溶解液容器と、 前記連結口部に連結する連結管を底部に有する有 底筒状のケースと、 底部に開口部が設けられ、 前記ケース内に、 軸方向に 移動可能に保持される固定治具と、 弾性材からなる栓により封止された口 部を前記固定治具の底部内に嵌入させた状態で、 前記固定治具とともに移 動可能に、 前記ケース内に保持された薬剤バイアルと、 この薬剤バイアル の口部の前記ケース底部側に形成される密閉空間内に、 前記軸方向に移動 可能に保持された中空の両頭針と、 前記ケースの内壁もしくは前記固定治 具の外壁に形成された排気用の溝と、 前記ケースに対して薬剤バイアルが 押し込まれる前の状態では、 前記密閉空間の気密状態を維持し、 前記ケー スに対して薬剤バイアルが押し込まれ、 ケース底部に向かって移動する間 、 前記排気用の溝を塞ぐことなく前記ケース内を滑動する遮蔽体とを備え た構成とした。 In order to solve the above-mentioned problem, the present invention has a closed connection port, a sealed solution container, and a bottomed cylindrical shape having a connection pipe connected to the connection port at the bottom. A case, an opening provided in the bottom, a fixing jig held in the case movably in the axial direction, and an opening sealed with a stopper made of an elastic material inside the bottom of the fixing jig. A medicine vial held in the case so as to be movable together with the fixing jig while being fitted in the medicine vial; A hollow double-ended needle movably held in the axial direction in a sealed space formed on the case bottom side of the mouth portion, and an exhaust air formed on the inner wall of the case or the outer wall of the fixing jig. In a state before the medicine vial is pushed into the case, the hermetically sealed state of the closed space is maintained, and while the medicine vial is pushed into the case and moves toward the case bottom, And a shielding body that slides in the case without closing the exhaust groove.
また、 本発明は、 前記口部を、 前記栓の抜け止め用として、 この栓の外 側に環状のキャップを固定して形成するとともに、 前記固定治具の底部と 前記キヤップとの間に環状の弾性部材を介在させるとともに、 前記キヤッ プの天面開口部の緣部を前記栓の側に折り曲げ、 この栓の天面に気密状 圧着させて形成した。  In addition, the present invention is characterized in that the mouth portion is formed by fixing an annular cap on the outer side of the stopper so as to prevent the stopper from coming off, and an annular cap is provided between the bottom of the fixing jig and the cap. The elastic member was interposed, and the upper part of the top opening of the cap was bent toward the plug, and the cap was air-tightly pressed to the top surface of the cap.
さらに、 本発明は、 前記ケース内に嵌入させられた前記薬剤バイアルの 底部に当接させた状態で前記ケースに取り付けられ、 かつその取り付け部 を破壊することなく前記底部から離れられな L、状態で前記ケースに取り付 けられた吊り具を設けて形成した。 図面の簡単な説明  Further, the present invention relates to a state where the medicine vial is attached to the case in a state of being in contact with the bottom of the medicine vial fitted in the case, and is not separated from the bottom without destroying the attached portion. In this case, a hanger attached to the case was provided. BRIEF DESCRIPTION OF THE FIGURES
第 1図は、 本発明の第一実施例に係る医療用容器の斜視図である。 第 2図は、 第 1図に示す医療用容器の分解斜視図である。  FIG. 1 is a perspective view of a medical container according to a first embodiment of the present invention. FIG. 2 is an exploded perspective view of the medical container shown in FIG.
第 3図は、 第 1図に示す医療用容器における薬剤バイアル固定治具の 縦断面図である。  FIG. 3 is a longitudinal sectional view of a drug vial fixing jig in the medical container shown in FIG.
第 4図は、 第 1図に示す医療用容器における両頭針の縦断面図である 第 5図は、 第 1図に示す医療用容器におけるケースの縦断面図である 第 6図は、 第 5図に示す医療用容器の VI— VI線断面図である。 FIG. 4 is a longitudinal sectional view of a double-ended needle in the medical container shown in FIG. 1. FIG. 5 is a longitudinal sectional view of a case in the medical container shown in FIG. FIG. 6 is a sectional view taken along line VI-VI of the medical container shown in FIG.
第 7図は、 第 1.図に示す医療用容器の連通操作前の状態を示す一部破 断正面図である。  FIG. 7 is a partially broken front view showing a state before a communication operation of the medical container shown in FIG. 1.
第 8図は、 第 1図に示す医療用容器の連通操作開始直後の状態を示す 一部破断正面図である。  FIG. 8 is a partially broken front view showing a state immediately after the start of the communication operation of the medical container shown in FIG. 1.
第 9図は、 第 1図に示す医療用容器の連通操作完了時の状態を示す一 部破断正面図である。  FIG. 9 is a partially cutaway front view showing a state at the time of completion of the communication operation of the medical container shown in FIG. 1.
第 1 0図は、 第 1図に示す医療用容器の空気抜き孔を空気抜き溝に代 替した本発明の第二実施例に係る医療用容器の構造を示す一部破断正面図 である。  FIG. 10 is a partially cutaway front view showing the structure of the medical container according to the second embodiment of the present invention in which the air vent holes of the medical container shown in FIG. 1 are replaced with air vent grooves.
.第 1 1図は、 本発明の第三実施例に係る医療用容器の一部破断正面図 である。  FIG. 11 is a partially cutaway front view of a medical container according to a third embodiment of the present invention.
第 1 2図は、 本発明の第四実施例に係る医療用容器の一部破断正面図 である。  FIG. 12 is a partially broken front view of a medical container according to a fourth embodiment of the present invention.
第 1 3図は、 本発明の第五実施例に係る医療用容器の一部破断正面図 である。  FIG. 13 is a partially cutaway front view of a medical container according to a fifth embodiment of the present invention.
第 1 4図は、 本発明の第六実施例に係る医療用容器の一部破断正面図 である。  FIG. 14 is a partially cutaway front view of a medical container according to a sixth embodiment of the present invention.
第 1 5図は、 本発明の第七実施例に係る医療用容器の一部破断正面図 である。  FIG. 15 is a partially cutaway front view of the medical container according to the seventh embodiment of the present invention.
第 1 6図は、 第 1 5図に示す医療用容器の吊り具の取り付け前の状態 の一例を示す部分断面図である。  FIG. 16 is a partial cross-sectional view showing an example of a state of the medical container shown in FIG. 15 before the hanging tool is attached.
第 1 7図は、 第 1 5図に示す医療用容器の吊り具の取り付け後の状態 の一例を示す部分断面図である。 第 1 8図は、 第 1 5図に示す医療用容器の使用前の状態を示す斜視図 である。 FIG. 17 is a partial cross-sectional view showing an example of a state after the hanging device of the medical container shown in FIG. 15 is attached. FIG. 18 is a perspective view showing a state before use of the medical container shown in FIG.
第 1 9図は、 第 1 5図に示す医療用容器の使用後の状態を示す斜視図 である。 実施例の詳細な説明  FIG. 19 is a perspective view showing a state after use of the medical container shown in FIG. Detailed description of the embodiment
以下、 本発明の実施例を添付図面を参照しつつ説明する。  Hereinafter, embodiments of the present invention will be described with reference to the accompanying drawings.
第 1図は、 本発明の第一実施例に係る医療用容器の斜視図であり、 1は 溶解液容器、 2は薬剤バイアル、 3は薬剤バイアル固定治具、 4は有底筒 状のケース、 5は連結部を示している。  FIG. 1 is a perspective view of a medical container according to a first embodiment of the present invention, wherein 1 is a solution container, 2 is a drug vial, 3 is a drug vial fixing jig, and 4 is a bottomed cylindrical case. , 5 indicate a connecting portion.
溶解液容器 1は、 熱可塑性のポリオレフィン系樹脂、 軟質の塩化ビニノ]/ 樹脂、 エチレン一酢酸ビニル共重合体等の材質で形成された可撓性の容器 で、 上部に薄膜 3 2 (第 7図参照) で封止された連結口部 7、 下部にゴム 栓で密封された薬液取り出し口部 9を具備し、 溶解液が充填されている。 薬剤バイアル 2は、 口部がゴム栓で密封された薬剤入り容器である。 ケース 4の底部は、 ケース 4の本体と一体に形成された空洞の連結管 6 を具備している。 また、 ケース 4は、 その上端にフランジ部、 外壁上部に 吊り具 8および吊り具枢支部 1 0を具備している。 吊り具 8は、 ケース 4 の外壁に具備された吊り具枢支部 1 0により枢支されている。  The dissolution liquid container 1 is a flexible container formed of a material such as a thermoplastic polyolefin resin, soft vinylino chloride / resin, or ethylene-vinyl acetate copolymer, and a thin film 3 2 (No. 7) It has a connection port 7 sealed with, and a chemical solution outlet 9 sealed at the bottom with a rubber stopper, and is filled with a solution. The drug vial 2 is a drug-containing container whose mouth is sealed with a rubber stopper. The bottom of the case 4 has a hollow connecting pipe 6 formed integrally with the main body of the case 4. The case 4 has a flange at the upper end thereof, and a hanger 8 and a hanger pivot 10 at the upper part of the outer wall. The hanger 8 is pivotally supported by a hanger pivot 10 provided on the outer wall of the case 4.
連結部 5は、 前述の連結管 6と連結口部 7から成り、 両者は気密に嵌合 、 係止されている。  The connecting part 5 is composed of the connecting pipe 6 and the connecting port part 7 described above, and both are fitted and locked in an airtight manner.
次に第 2図〜第 5図に基づき、 前記実施例の医療用容器の構造について 詳述する。 第 2図に示すように、 薬剤バイアル 2は、 その口部 1 1を下に して配置され、 その口部 1 1は薬剤バイアル固定治具 3の凹所 2 0 (第 3 図参照) 内に嵌入させられる。 環状パッキン 1 2は、 薬剤バイアル固定治 具 3の内壁に形成された環状溝 1 3に環装される。 環状パッキン 1 2は、 大量生産されることによって生じる薬剤バイアル 2の胴部直径のバラツキ でケース 4内の気密性が損なわれることを防止している。 環状パッキン 1 6は、 薬剤バイアル固定治具 3の胴部外壁に形成された環状溝 1 4に環装 される。 環状パッキン 1 7は、 薬剤バイアル固定治具 3のフランジ部に形 成された環状溝 1 5に環装される。 前述したように、 薬剤バイアル 2と薬 剤バイアル固定治具 3は、 環状パッキン 1 2 , 1 6 , 1 7を介してケース 4に気密かつ移動可能に保持される。 この薬剤バイアル 2を嵌入させた薬 剤バイアル固定治具 3とケース 4の底部との間には、 密閉空間が形成され 、 この密閉空間内に両頭針 1 8が設置されている。 Next, the structure of the medical container of the above embodiment will be described in detail with reference to FIGS. As shown in FIG. 2, the drug vial 2 is placed with its mouth 11 down, and the mouth 11 is in the recess 20 of the drug vial fixing jig 3 (see FIG. 3). Is inserted into. Ring packing 1 2 It is installed in an annular groove 13 formed in the inner wall of the tool 3. The annular packing 12 prevents the airtightness in the case 4 from being impaired due to the variation in the diameter of the body of the drug vial 2 caused by mass production. The annular packing 16 is mounted in an annular groove 14 formed in the outer wall of the body of the drug vial fixing jig 3. The annular packing 17 is mounted in an annular groove 15 formed in a flange portion of the drug vial fixing jig 3. As described above, the drug vial 2 and the drug vial fixing jig 3 are airtightly and movably held by the case 4 via the annular packings 12, 16, and 17. A sealed space is formed between the drug vial fixing jig 3 into which the drug vial 2 is inserted and the bottom of the case 4, and a double-ended needle 18 is installed in the sealed space.
第 3図に示すように、 薬剤バイアル固定治具 3は、 その凹所 2 0の底部 に両頭針 1 8の刃面を通過させるための開口部 2 1を有している。 また、 薬剤バイアル固定治具 3のフランジ部には、 上下に貫通する空気抜き孔 2 2が設けられている。 薬剤バイアル固定治具 3の材質としては、 硬質のプ ラスチックやゴム等が好ましい。 また、 環状パッキン 1 2 , 1 6, 1 7を 、 薬剤バイアル固定治具 3と一体に成形することも可能である。 環状パッ キン 1 2 , 1 6 , 1 7の材質としては、 ポリスチレン等の軟質のプラスチ ック、 シリコンゴム、 ブタジエンゴム、 イソプレンゴム等が好ましい。 第 4図に示すように、 両頭針 1 8は、 その中間に薬剤バイアル口部ゴム 栓 3 7 (第 7図参照) を刺通する際に、 刺通深さを一定に保つハブ 2 3、 この両頭針 1 8をケース 4の内壁に形成された環状溝 2 6 (第 2図参照) に係止するための係止部 2 4、 および液漏れ防止部 2 5を具備している。 両頭針 1 8の材質としては、 ステンレススチール製の金属針や硬質プラス チック製樹脂等が好ましい。  As shown in FIG. 3, the drug vial fixing jig 3 has an opening 21 for passing the blade surface of the double-ended needle 18 at the bottom of the recess 20. The flange portion of the drug vial fixing jig 3 is provided with an air vent hole 22 penetrating vertically. The material of the drug vial fixing jig 3 is preferably a hard plastic or rubber. Further, the annular packings 12, 16, and 17 can be formed integrally with the drug vial fixing jig 3. The material of the annular packings 12, 16, 16 is preferably a soft plastic such as polystyrene, silicon rubber, butadiene rubber, isoprene rubber, or the like. As shown in FIG. 4, the double-ended needle 18 is provided with a hub 23, which keeps the penetration depth constant when the rubber vial mouth rubber stopper 37 (see FIG. 7) is pierced therebetween. The double-ended needle 18 is provided with an engaging portion 24 for engaging an annular groove 26 (see FIG. 2) formed on the inner wall of the case 4 and a liquid leakage preventing portion 25. As the material of the double-ended needle 18, a metal needle made of stainless steel, a hard plastic resin, or the like is preferable.
第 5図に示すように、 ケース 4には、 その内壁に 3箇所の環状溝 2 6、 2 7、 2 8および排気用の溝 2 9が形成されている。 排気用の溝 2 9は、 軸方向に形成されかつ、 ケース上部側の 2つの環状溝 2 7, 2 8の間に形 成されている。 また、 この排気用の溝 2 9は、 第 6図の断面図からも分か るように、 ケース 4の内壁の 2個所にそれぞれ向かい合うように形成され ている。 ケース 4の底部に位置する連結管 6は、 連結部ゴム栓 1 9 (第 2 図参照) が嵌入させられる貫通孔 3 1と溶解液容器 1の連結部嵌合用突起 3 8 (第 7図参照) が嵌入する嵌入溝 3 0を具備している。 As shown in FIG. 5, the case 4 has three annular grooves 26, 27, 28 and a groove 29 for exhaust are formed. The exhaust groove 29 is formed in the axial direction, and is formed between the two annular grooves 27 and 28 on the upper side of the case. Further, as can be seen from the cross-sectional view of FIG. 6, the exhaust grooves 29 are formed so as to face two portions of the inner wall of the case 4 respectively. The connecting tube 6 located at the bottom of the case 4 has a through hole 31 into which the connecting portion rubber plug 19 (see FIG. 2) is fitted and a connecting portion fitting projection 3 8 of the solution container 1 (see FIG. 7). ) Is provided with a fitting groove 30 into which the fits.
第 7図に示すように、 薬剤バイアル 2を嵌入した薬剤バイアル固定治具 3は、 環状パッキン 1 6が環状溝 2 8内に、 また環状パッキン 1 7が環状 溝 2 7に密着させた状態で、 ケース 4内に揷着される。 薬剤バイアル固定 治具 3は、 その下方にフランジ部、 上端部に外方鍔部 3 3と内方鍔部 3 4 からなる鍔部を有している。 さらに、 薬剤バイアル固定治具 3には、 その 胴部側壁に凸部 3 6と少なくとも 2力所の切込み部 3 5が設けられている 前述のように、 薬剤バイアル 2を嵌入した薬剤バイアル固定治具 3をケ —ス 4内に挿着することによって、 薬剤バイアル固定治具 3とケース 4の 底部との間には密閉空間が形成される。 環状パッキン 1 2 , 1 6により前 記密閉空間内への外気の進入が防止でき、 密閉空間内の無菌性が保証され る。 二つの環状パッキン 1 6、 1 7が、 それぞれ環状溝 2 7 , 2 8内に嵌 まり込むことによって、 輸送中に生じる振動等のために、 ケース 4内にお ける薬剤バイアル固定治具 3の位置が変動することが回避される。  As shown in FIG. 7, the medicine vial fixing jig 3 in which the medicine vial 2 is fitted is a state in which the annular packing 16 is in close contact with the annular groove 28 and the annular packing 17 is in close contact with the annular groove 27. , Placed in case 4. The drug vial fixing jig 3 has a flange portion below the jig, and a flange portion including an outer flange portion 33 and an inner flange portion 34 at an upper end portion. Further, the drug vial fixing jig 3 is provided with a convex portion 36 and at least two notches 35 on its body side wall. As described above, the drug vial fixing jig into which the drug vial 2 is inserted is provided. By inserting the tool 3 into the case 4, a sealed space is formed between the drug vial fixing jig 3 and the bottom of the case 4. The annular packings 12 and 16 prevent the outside air from entering the above-mentioned closed space, and assure sterility in the closed space. The two annular packings 16 and 17 fit into the annular grooves 27 and 28, respectively, so that the vibration via the transportation etc. occurs during transportation. Variations in position are avoided.
次に、 前述した医療用容器の使用方法について、 第 8図、 第 9図を参照 しつつ説明する。  Next, the method of using the medical container described above will be described with reference to FIGS.
第 8図は、 薬剤バイアル 2と溶解液容器 1の連通操作を開始した直後の 状態を示し、 第 9図は連通操作終了後の状態を示す。 薬剤バイアル 2と溶 解液容器 1を連通させるためには、 まず、 薬剤バイアル 2の底部を下方へ 押圧する。 より具体的には、 薬剤バイアル 2の底面を指で押し下げ薬剤バ ィアル固定治具 3を.溶解液容器 1に向け下降させる。 この操作により、 二 つの環状パッキン 1 6 , 1 7が環状溝 2 7, 2 8から外れる。 環状パツキ ン 1 6は、 環状溝 2 8から外れてケース 4の底部に向かって下降する間、 排気用の溝 2 9を塞ぐことなくケース 4内を滑動する。 FIG. 8 shows a state immediately after the communication operation between the drug vial 2 and the solution container 1 is started, and FIG. 9 shows a state after the communication operation is completed. Soluble with drug vial 2 In order to communicate the lysis solution 1, first, the bottom of the drug vial 2 is pressed downward. More specifically, the bottom surface of the drug vial 2 is pressed down with a finger, and the drug vial fixing jig 3 is lowered toward the dissolution liquid container 1. By this operation, the two annular packings 16 and 17 come off the annular grooves 27 and 28. While the annular packing 16 is disengaged from the annular groove 28 and descends toward the bottom of the case 4, it slides inside the case 4 without closing the exhaust groove 29.
前述のように、 環状パッキン 1 6が排気用の溝 2 9を塞ぐことなくケー ス 4内を滑動することにより、 薬剤バイアル固定治具 3の下降により縮小 してゆくケース 4内の密閉空間内の空気は、 空気抜き孔 2 2を通り排気用 の溝 2 9からケース 4外へ排出される。 この排気により、 薬剤バイアル 2 を保持した薬剤バイアル固定治具 3は、 縮小した密閉空間内の空気により 押戻されることなく容易に下降することができる。 さらに薬剤バイアル固 定治具 3を押し下げると、 両頭針 1 8の係止部 2 4の先端が環状溝 2 6か ら外れ、 両頭針 1 8は溶解液容器 1に向かって下降する。 これによつて、 第 9図に示すように連結部 5の連結部ゴム栓 1 9と薄膜 3 2および反対側 の薬剤バイアル口部ゴム栓 3 7が両頭針 1 8によって瞬時に剌通される。 この時、 環状パッキン 1 6は環状溝 2 7に嵌まり込み、 薬剤バイアル固定 治具 3とケース 4の底部との間には再び密閉空間が形成される。 また、 環 状パッキン 1 6が環状溝 2 7に、 環状パッキン 1 7が環状溝 2 6に嵌まり 込むことにより、 バイアル固定治具 3の浮き上がりを防止している。 なお 、 第 1 0図に示す本発明の第二実施例のように、 空気抜き孔 2 2 (第 9図 参照) は、 排気用の溝 2 9と同じ形状の空気抜き溝 3 9に代替できる。 さらに、 前述した薬剤バイアル 2の浮き上がりは、 薬剤バイアル 2の底 面を押圧する連通操作によって薬剤バイアル固定治具 3が下降する時、 凸 部 3 6がケース 4の内壁に当接することで薬剤固定治具 3上部の側壁が軸 芯に向かって内側に変形し、 この側壁の変形に伴い内方鍔部 3 4が薬剤バ ィアル 2の底部を押えることにより防止される。 As described above, the annular packing 16 slides in the case 4 without closing the exhaust groove 29, so that the inside of the closed space in the case 4 is reduced by the lowering of the drug vial fixing jig 3. The air is discharged from the case 4 through the exhaust groove 29 through the air vent hole 22. By this exhaust, the drug vial fixing jig 3 holding the drug vial 2 can be easily lowered without being pushed back by the air in the reduced closed space. When the drug vial fixing jig 3 is further pushed down, the tip of the locking portion 24 of the double-ended needle 18 is disengaged from the annular groove 26, and the double-ended needle 18 is lowered toward the solution container 1. As a result, as shown in FIG. 9, the connecting part rubber stopper 19 of the connecting part 5 and the thin film 32 and the medicine vial mouth rubber stopper 37 on the opposite side are instantaneously stimulated by the double-ended needle 18. . At this time, the annular packing 16 is fitted into the annular groove 27, and a closed space is formed again between the medicine vial fixing jig 3 and the bottom of the case 4. The annular packing 16 fits into the annular groove 27, and the annular packing 17 fits into the annular groove 26, thereby preventing the vial fixing jig 3 from floating. As in the second embodiment of the present invention shown in FIG. 10, the air vent hole 22 (see FIG. 9) can be replaced with an air vent groove 39 having the same shape as the exhaust groove 29. Furthermore, when the medicine vial 2 is lifted by the communication operation of pressing the bottom surface of the medicine vial 2 and the medicine vial fixing jig 3 is lowered, the medicine vial 2 comes into contact with the inner wall of the case 4 by fixing the medicine vial. Jig 3 The upper side wall is the axis It is deformed inward toward the core, and is prevented by the inner flange 34 pressing the bottom of the drug vial 2 with the deformation of the side wall.
薬剤バイアル 2と溶解液容器 1を連通させた後は、 これらを水平にする 力、、 薬剤バイアル 2よりも溶解液容器 1を上に持ち上げて、 壁面を押圧し 、 溶解液を薬剤バイアル 2内に移行させて薬剤を溶解させる。 薬剤を完全 に溶解させた後、 溶液を溶解液容器 1に戻し、 吊り具 8を輸液スタンドの フックに吊るして溶解液容器 1の薬液取り出し口部 9に輸液セッ トを取り 付け、 患者に点滴静注する。  After the drug vial 2 and the dissolution liquid container 1 are communicated with each other, the force for leveling them, the lifting of the dissolution liquid container 1 above the drug vial 2, the pressing of the wall surface, and the dissolving liquid in the drug vial 2 To dissolve the drug. After the drug is completely dissolved, the solution is returned to the dissolution solution container 1, the hanging device 8 is hung on the hook of the infusion stand, the infusion set is attached to the solution outlet 9 of the solution solution container 1, and the patient is infused. Inject intravenously.
本実施例の医療用容器を使用した後は、 薬剤バイアル固定治具 3の上端 部に設けられた外方鍔部 3 3を引き上げ、 ケース 4より薬剤バイアル固定 治具 3を取り出すことができる。 薬剤バイアル固定治具 3を取り出した ί孝 は、 薬剤バイアル固定治具 3に嵌入されている薬剤バイアル 2を、 切込み 部 3 5より露出している薬剤バイアル 2の側壁を指でつまみ引き上げるこ とにより取り出すことができる。 このように、 この医療用容器は、 使用後 の分別廃棄を容易に行える特徴を有している。  After using the medical container of the present embodiment, the drug vial fixing jig 3 can be taken out of the case 4 by pulling up the outer flange 33 provided at the upper end of the drug vial fixing jig 3. Takataka who took out the drug vial fixing jig 3 picks up the drug vial 2 inserted into the drug vial fixing jig 3 with his finger on the side wall of the drug vial 2 exposed from the cutout portion 3 5 and pulls it up. Can be taken out. As described above, this medical container has a feature that it can be easily separated and discarded after use.
第 1 1図は、 本発明の第三実施例に係る医療用容器を示す。 第 1 1図か ら分かるように、 本実施例は、 先の実施例においてケース 4の内壁に形成 されていた排気用の溝 2 9が、 薬剤バイアル固定治具 3の胴部外壁に形成 されている。 また、 先の実施例において、 薬剤バイアル固定治具 3の胴部 外壁に環装されていた環状パッキンは、 ケース 4の内壁に環装されている 。 これ以外の構造および特徴は、 第 6図に示す先の実施例と実質的に異な るところはない。  FIG. 11 shows a medical container according to a third embodiment of the present invention. As can be seen from FIG. 11, in this embodiment, the exhaust groove 29 formed on the inner wall of the case 4 in the previous embodiment is formed on the outer wall of the body of the drug vial fixing jig 3. ing. Further, in the above embodiment, the annular packing mounted on the outer wall of the body of the drug vial fixing jig 3 is mounted on the inner wall of the case 4. The other structures and features are not substantially different from the previous embodiment shown in FIG.
なお、 第 1 0 , 1 1図には、 吊り具 8は示されていないが、 第二, 第三 実施例では第一実施例と同様に吊り具 8は設けられている。  10 and 11, the hanging member 8 is not shown, but in the second and third embodiments, the hanging member 8 is provided as in the first embodiment.
以上の説明より明らかなように、 前記実施例に係る医療用容器によれば 、 溶解液容器、 有底筒状のケース、 薬剤バイアルを、 その口部を下にして 挿着した筒状の薬剤バイアル固定治具、 中空の両頭針、 排気用の溝、 およ び排気用の溝を塞ぐことなく前記ケース内を滑動する遮蔽体とを具備して いるので、 薬剤バイアルを押圧するという簡単な操作で薬剤バイアルと溶 解液容器とを無菌的かつ迅速に連通させることができ、 薬剤の溶解操作を 速やかに行う とが可能となる。 As is clear from the above description, according to the medical container according to the embodiment, , Dissolution solution container, bottomed cylindrical case, drug vial with its mouth down, cylindrical drug vial fixing jig, hollow double-ended needle, exhaust groove, and exhaust And a shielding body that slides in the case without closing the groove, so that the medicine vial and the solution container can be aseptically and quickly communicated by a simple operation of pressing the medicine vial. The dissolution operation of the drug can be performed quickly.
しかも、 この前記実施例に係る医療用容器によれば、 溶解した薬剤を点 滴する際、 薬剤バイアルがケース内に押し込まれた状態で保持されている ため、 容器の全長が短く、 医療用容器と点滴投与部位間の落差を充分に大 きくすることができる。  Moreover, according to the medical container according to the above embodiment, the drug vial is held in a state of being pushed into the case when the dissolved drug is infused, so that the total length of the container is short, and the medical container is And the drop between the infusion administration sites can be made sufficiently large.
さらに、 前記実施例に係る医療用容器によれば、 部品数が少なく、 容舉 形状が小さいため、 使用済みの廃棄物が少なく、 簡単に分別廃棄できると いう効果を奏する。  Further, according to the medical container according to the above embodiment, the number of parts is small and the shape of the egg is small, so that there is an effect that the used waste is small and the waste can be easily separated and discarded.
第 1 2図は、 本発明の第四実施例に係る医療用容器を示し、 前記第一実 施例に係る医療用容器とは、 薬剤バイアル 2の口部および薬剤バイアル固 定治具 3の底部を除き、 他は実質的に同一であり、 共通する部分について は同一番号を付して説明を省略する。  FIG. 12 shows a medical container according to a fourth embodiment of the present invention. The medical container according to the first embodiment includes the mouth of the drug vial 2 and the drug vial fixing jig 3. Except for the bottom part, the other parts are substantially the same, and the common parts are denoted by the same reference numerals and description thereof is omitted.
本実施例では、 薬剤バイアル 2の口部を封止している弾性材、 例えばゴ ム製の栓 3 7 aの外側に環状のキャップ 4 1が固定してあり、 栓 3 7 aの 天面と薬剤バイアル 2の首部の外周部を環状のキヤップ 4 1で巻き締めて あり、 栓 3 7 aがこの口部から抜けるのを防止して、 薬剤バイアル 2の気 密性を確保している。 また、 薬剤バイアル固定治具 3の底部とキャップ 4 1との間には、 断面 L形の環状の弾性部材 4 2を介在させてあり、 第 1 2 図においてキャップ 4 1の上方の薬剤バイアル固定治具 3内の空間と薬剤 バイアル固定治具 3の底部の開口部側とを完全に遮断している。 さらに、 キャップ 4 1の天面開口部の縁部を栓 3 7 a側に折り曲げ、 拴 3 7 aの天 面に気密状に圧着させて形成してあり、 キャップ 4 1の内周面と薬剤バイ アル固定治具 3の底部の開口部とを完全に遮断している。 In this embodiment, an annular cap 41 is fixed to the outside of an elastic material sealing the mouth of the drug vial 2, for example, a rubber stopper 37a, and the top surface of the stopper 37a is fixed. The outer periphery of the neck of the drug vial 2 is wound around with an annular cap 41, and the stopper 37a is prevented from falling out of the mouth to ensure the hermeticity of the drug vial 2. An annular elastic member 42 having an L-shaped cross section is interposed between the bottom of the drug vial fixing jig 3 and the cap 41, and the drug vial above the cap 41 is fixed in FIG. The space inside the jig 3 and the opening at the bottom of the drug vial fixing jig 3 are completely shut off. further, The edge of the opening at the top of the cap 41 is bent toward the stopper 37a side, and is pressed against the top of the 37a in an airtight manner, and the inner peripheral surface of the cap 41 and the drug vial are formed. The opening at the bottom of the fixture 3 is completely shut off.
現在、 キャップ 4 1と栓 3 7 aとの間を滅菌すること、 殺菌することは 非常に困難であるが、 本実施例のように、 弾性部材 4 2を設けることによ り、 キャップ 4 1と栓 3 7 aとの間に菌が存在していて、 この菌がキヤッ プ 4 1の上方の薬剤バイアル固定治具 3内の空間に出ても、 この菌が薬剤 バイアル固定治具 3の底部の開口部側に出て来るのを防止している。 また 、 キャップ 4 1の天面開口部の縁部を栓 3 7 a側に折り曲げ、 栓 3 7 aの 天面に気密状に圧着させて形成することにより、 キャップ 4 1と栓 3 7 a との間に菌が存在していても、 この菌が、 薬剤バイャル固定治具 3の開 ςι 部側に出てくるのを防止している。 この結果、 両頭針 1 8を収容した空間 の無菌性をより一層確実に保証されるようになついる。  At present, it is very difficult to sterilize and sterilize the space between the cap 41 and the stopper 37a. However, by providing the elastic member 42 as in this embodiment, the cap 41 Even if bacteria exist between the stopper and the stopper 37a and this bacteria comes out of the space inside the drug vial fixing jig 3 above the cap 41, the bacteria may It is prevented from coming out to the bottom opening side. Also, the edge of the opening of the top surface of the cap 41 is bent toward the stopper 37a side, and the cap 41 is tightly pressed against the top surface of the stopper 37a to form the cap 41 and the stopper 37a. Even if bacteria exist between the two, this bacteria is prevented from coming out to the open side of the drug vial fixing jig 3. As a result, the sterility of the space accommodating the double-ended needle 18 can be more reliably assured.
この他、 本実施例によれば、 前記各実施例による効果も得られる。  In addition, according to the present embodiment, the effects of the above embodiments can be obtained.
第 1 3図は、 本発明の第五実施例に係る医療用容器を示し、 前記第四実 施例に係る医療用容器とは、 弾性部材 4 2に代えて弾性部材 4 2 aを設け た点を除き、 他は実質的に同一であり、 共通する部分については同一番号 を付して説明を省略する。  FIG. 13 shows a medical container according to a fifth embodiment of the present invention. The medical container according to the fourth embodiment is provided with an elastic member 42 a instead of the elastic member 42. Except for this point, the other parts are substantially the same, and the common parts are denoted by the same reference numerals and description thereof is omitted.
即ち、 この第五実施例では、 筒状の弾性部材 4 2 aが使用されている。 第 1 4図は、 本発明の第六実施例に係る医療用容器を示し、 前記第四実 施例に係る医療用容器とは、 弾性部材 4 2に代えて弾性部材 4 2 bを設け た点を除き、 他は実質的に同一であり、 共通する部分については同一番号 を付して説明を省略する。  That is, in the fifth embodiment, the cylindrical elastic member 42a is used. FIG. 14 shows a medical container according to a sixth embodiment of the present invention. The medical container according to the fourth embodiment is different from the medical container according to the fourth embodiment in that an elastic member 42 b is provided instead of the elastic member 42. Except for this point, the other parts are substantially the same, and the common parts are denoted by the same reference numerals and description thereof is omitted.
即ち、 この第六実施例では、 円板の中央部に開口部を設けた形状の弾性 部材 4 2 bが使用されている。 そして、 この第五, 第六実施例のように形成することにより、 第四実施 例の場合と同様の効果が得られる。 即ち、 第一〜第三実施例による効果に 加えて、 キャップ 4.1と栓 3 7 aとの間に菌が存在していても、 この菌が 薬剤バイャル固定治具 3の開口部側に出てくるのを防止し、 両頭針 1 8を 収容した空間の無菌性をより一層確実に保証されるようになっている。 なお、 第四,' 五, 六実施例に関して、 空気抜き孔 2 2に代えて第二実施 例における空気抜き溝 3 9を設けてもよく、 さらに排気用の溝 2 9をケー ス 4の内面ではなく、 第三実施例のように薬剤バイアル固定治具 3の外周 に設けてもよい。 That is, in the sixth embodiment, the elastic member 42b having an opening at the center of the disk is used. Then, by forming them as in the fifth and sixth embodiments, the same effects as in the case of the fourth embodiment can be obtained. That is, in addition to the effects of the first to third embodiments, even if bacteria exist between the cap 4.1 and the stopper 37a, the bacteria emerge at the opening side of the drug vial fixing jig 3. In this way, the space containing the double-ended needle 18 is more reliably assured of sterility. In the fourth, fifth and sixth embodiments, the air vent groove 39 in the second embodiment may be provided instead of the air vent hole 22. Further, the exhaust groove 29 is provided not on the inner surface of the case 4. Alternatively, it may be provided on the outer periphery of the drug vial fixing jig 3 as in the third embodiment.
また、 第 1 2 , 1 3および 1 4図には、 吊り具 8は示されていないが、 第四, 第五および第六実施例では、 第一実施例と同様に吊り具 8は設け れている。  Further, although the hanging members 8 are not shown in FIGS. 12, 13, and 14, the hanging members 8 are provided in the fourth, fifth, and sixth embodiments, similarly to the first embodiment. ing.
第 1 5〜1 9図は、 本発明の第七実施例に係る医療用容器を示し、 前記 第五実施例に係る医療用容器とは、 ケース 4に代えてケース 5 1を使用し ている点、 吊り具 8に代えて吊り具 5 2を使用している点を除き、 他は実 質的に同一であり、 共通する部分については、 互いに同一番号を付して説 明を省略する。  FIGS. 15 to 19 show a medical container according to a seventh embodiment of the present invention. The medical container according to the fifth embodiment uses a case 51 instead of the case 4. Except for the point and the point that the hanging tool 52 is used instead of the hanging tool 8, the others are substantially the same, and the common parts are denoted by the same reference numerals and the description is omitted.
吊り具 5 2は、 薬剤バイアル固定治具 3内に嵌入させた薬剤バイアル 2 の底部に当接させた状態で、 ケース 5 1に取り付けられており、 その取り 付け部 5 3は、 吊り具 5 2を一旦ケース 5 1から取り出すと元の状態には 戻せないようになつている。  The hanging tool 52 is attached to the case 51 in a state of being in contact with the bottom of the drug vial 2 fitted in the drug vial fixing jig 3, and the mounting portion 53 is provided with the hanging tool 5. Once 2 is removed from case 51, it cannot be returned to its original state.
例えば、 第 1 6 , 1 7図に示すように、 ケース 5 1に形成した突出部 5 4を、 吊り具 5 2の下端部に形成した貫通孔 5 5に嵌入させ、 その後突出 部 5 4の頭部を、 貫通孔 5 5の内径よりも大きくなるように押圧して、 径 方向に拡大させる。 そして、 このように吊り具 5 2を取り付けることによ り、 ケース 5 1内に嵌入させられた薬剤バイアル 2および薬剤バイアル固 定治具 3が、 薬剤バイアル 2の使用前に、 ケース 5 1から取り出されるこ とにより生じる問題を回避できる。 For example, as shown in FIGS. 16 and 17, the projecting portion 54 formed in the case 51 is fitted into a through hole 55 formed at the lower end of the hanging tool 52, and then the projecting portion 54 is formed. The head is pressed so as to be larger than the inner diameter of the through-hole 55 to expand in the radial direction. Then, by attaching the suspenders 52 in this manner, Therefore, it is possible to avoid a problem that occurs when the medicine vial 2 and the medicine vial fixing jig 3 fitted in the case 51 are taken out of the case 51 before the use of the medicine vial 2.
即ち、 薬剤バイアル固定治具 3内の薬剤バイアル 2を取り出し、 再度こ の薬剤バイアル 2を薬剤バイアル固定治具 3内に保持させることを許容す ると、 ケース 5 1内は汚染されることになる。 本実施例では、 この吊り具 5 2によって、 使用前の薬剤バイアル 2および薬剤バイアル固定治具 3を 、 吊り具 5 2およびその取り付け部 5 3を破壊することなく取り出すこと ができないようになっており、 これによりケース 5 1内の密閉空間の無菌 性を保つことが可能となっている。 また、 この吊り具 5 2によって、 薬剤 バイアル固定治具 3内の薬剤バイアル 2力、 誤つて他の薬剤バイアルと ¾ り換えられるのを防止している。  That is, if the drug vial 2 in the drug vial fixing jig 3 is taken out and the drug vial 2 is allowed to be held in the drug vial fixing jig 3 again, the case 51 becomes contaminated. Become. In this embodiment, the hanging tool 52 prevents the medicine vial 2 and the medicine vial fixing jig 3 before use from being taken out without breaking the hanging tool 52 and the mounting portion 53 thereof. As a result, it is possible to maintain the sterility of the closed space in the case 51. The hanging tool 52 prevents the medicine vial 2 in the medicine vial fixing jig 3 from being accidentally replaced with another medicine vial.
好ましくは、 第 1 8図に示すように、 吊り具 5 2は、 対向する内方鍔部 3 4の 4個の内周面の角部の内、 この 4個の角部で形成される四角形の対 角線上に位置する 2個の角部に当接するように取り付けられるのがよい。 斯る構造により、 薬剤バイアル 2の使用前に、 吊り具 5 2を横に倒して、 薬剤バイアル 2の底部から離そうとしても、 内方鍔部 3 4が障害となり、 吊り具 5 2を倒すことはできなくなる。  Preferably, as shown in FIG. 18, the hanging member 52 is a square formed by the four corners of the four inner peripheral surfaces of the opposed inner flange portion 34. It is good to be attached so that two corners located on the diagonal line of abutment may be contacted. With such a structure, before using the drug vial 2, even if the hanging tool 52 is tilted sideways so as to separate from the bottom of the drug vial 2, the inner flange 34 becomes an obstacle and the hanging tool 52 is tilted. You will not be able to do it.
薬剤バイアル 2の使用後は、 第 1 9図に示すように、 薬剤バイアル 2お よび薬剤ノ <ィァル固定治具 3は吊り具 5 2から離れているので、 吊り具 2 を横に倒すことにより、 薬剤ノ <ィアル 2および薬剤バイ 7ル固定治具 3を ケース 5 1から取り出すことができる。  After the use of the drug vial 2, as shown in Fig. 19, the drug vial 2 and the drug nozzle fixing jig 3 are separated from the hanging tool 52, so that the hanging tool 2 is turned over. The drug noial 2 and the drug vial fixing jig 3 can be taken out of the case 51.
なお、 吊り具 5 2の両脚部に予め切り込み部を形成しておき、 医療用容 器を使用後、 この切り込み部の所で吊り具 5 2を折り曲げて、 薬剤バイァ ル 2をケース 5 1から取り出すようにしてもよい。 また、 第七実施例に関して、 空気抜き孔 2 2に代えて第二実施例におけ る空気抜き溝 3 9を設けてもよく、 さらに排気用の溝 2 9をケース 5 1の 内面ではなく、 第三実施例のように薬剤バイアル固定治具 3の外周に設け てもよい。 Notches are formed in both legs of the hanging tool 52 in advance, and after using the medical container, the hanging tool 52 is bent at the notch to remove the drug vial 2 from the case 51. It may be taken out. Regarding the seventh embodiment, the air vent groove 39 in the second embodiment may be provided in place of the air vent hole 22. Further, the exhaust groove 29 is provided not on the inner surface of the case 51 but on the third surface. It may be provided on the outer periphery of the medicine vial fixing jig 3 as in the embodiment.
さらに、 第七実施例に関して、 弾性部材 4 2 aに代えて、 弾性部材 4 2 或は 4 2 bを使用してもよい。  Further, regarding the seventh embodiment, the elastic member 42 or 42b may be used instead of the elastic member 42a.
この第七実施例についても第一実施例の場合と同様の効果が得られるこ とは明らかである。  It is apparent that the same effects as those of the first embodiment can be obtained in the seventh embodiment.

Claims

請 求 の 範 囲 The scope of the claims
1. 密封された連結口部を有する溶解液容器と、 前記連結口部に連結する 連結管を底部に有 る有底筒状のケースと、 底部に開口部が設けられ、 前 記ケース内に、 軸方向に移動可能に保持される固定治具と、 弾性材からな る栓により封止された口部を前記固定治具の底部内に嵌入させた状態で、 前記固定治具とともに移動可能に、 前記ケース内に保持された薬剤バイァ ルと、 この薬剤バイアルの口部の前記ケース底部側に形成される密閉空間 内に、 前記軸方向に移動可能に保持された中空の両頭針と、 前記ケースの 内壁もしくは前記固定治具の外壁に形成された排気用の溝と、 前記ケース に対して薬剤バイアルが押し込まれる前の状態では、 前記密閉空間の気密 状態を維持し、 前記ケースに対して薬剤バイアルが押し込まれ、 ケース摩 部に向かって移動する間、 前記排気用の溝を塞ぐことなく前記ケース内を 滑動する遮蔽体とを備えたことを特徴とする医療用容器。  1. a dissolving solution container having a sealed connection port, a bottomed cylindrical case having a connection pipe connected to the connection port at the bottom, and an opening at the bottom provided in the case; A fixing jig which is held movably in the axial direction, and which can be moved together with the fixing jig in a state where an opening sealed with a stopper made of an elastic material is fitted into the bottom of the fixing jig. A drug vial held in the case, a hollow double-ended needle held movably in the axial direction in a sealed space formed on the case bottom side of the mouth of the drug vial, An exhaust groove formed on the inner wall of the case or the outer wall of the fixing jig, and in a state before the medicine vial is pushed into the case, the hermetically sealed state of the closed space is maintained. Drug vial is pushed in While moving toward the scan milling unit, medical container, characterized in that a shield to slide in the casing without blocking the groove for the exhaust.
2. 密封された連結口部を有する溶解液容器と、 前記連結口部に連結する 連結管を底部に有する有底筒状のケースと、 底部に開口部が設けられ、 前 記ケース内に、 軸方向に移動可能に保持される固定治具と、 弾性材からな る栓により封止され、 かっこの栓の抜け止め用として、 この栓の外側に環 状のキャップを固定した口部を前記固定治具の底部内に嵌入させた状態で 、 前記固定治具とともに移動可能に、 前記ケース内に保持された薬剤バイ アルと、 この薬剤バイアルの口部の前記ケース底部側に形成される密閉空 間内に、 前記軸方向に移動可能に保持された中空の両頭針と、 前記ケース に対して薬剤バイアルが押し込まれる前の状態では、 前記密閉空間の気密 状態を維持し、 前記ケースに対して薬剤バイアルが押し込まれ、 ケース底 部に向かって移動する間、 このケース内を滑動し、 前記気密状態を一旦解 除し、 前記薬剤バイアルが押し込まれてしまった状態で、 前記密閉空間を 再度、 気密状態にする遮蔽体とを備えた医療用容器において、 前記固定治 具の底部と前記キャップとの間に環状の弾性部材を介在させるとともに、 前記キャップの天面.開口部の縁部を前記栓の側に折り曲げ、 この栓の天面 に気密状に圧着させたことを特徴とする医療用容器 2. a dissolving solution container having a sealed connection port, a bottomed cylindrical case having a connection pipe connected to the connection port at the bottom, and an opening provided at the bottom; A fixing jig that is held movably in the axial direction and a stopper made of an elastic material are sealed with a stopper formed of an elastic material. A medicine vial held in the case movably with the fixing jig in a state of being fitted into the bottom of the fixing jig, and a seal formed on the case bottom side of the mouth of the medicine vial. A hollow double-ended needle held movably in the axial direction in the space, and in a state before the drug vial is pushed into the case, the hermetically sealed state of the sealed space is maintained; Drug vial is pushed While moving toward the over scan bottom, and slide in this case, the airtight state once canceled, in a state in which the drug vial had been pushed, the enclosed space Again, in a medical container provided with a shield to make the airtight state, an annular elastic member is interposed between the bottom of the fixing jig and the cap, and the top surface of the cap. A medical container characterized by being folded to the side of the stopper and hermetically pressed to the top surface of the stopper.
3. 密封された連結口部を有する溶解液容器と、 前記連結口部に連結する 連結管を底部に有する有底筒状のケースと、 底部に開口部が設けられ、 前 記ケース内に、 軸方向に移動可能に保持される固定治具と、 弾性材からな る栓により封止された口部を前記固定治具の底部内に嵌入させた状態で、 前記固定治具とともに移動可能に、 前記ケース内に保持された薬剤バイァ ルと、 この薬剤バイアルの口部の前記ケース底部側に形成される密閉空間 内に、 前記軸方向に移動可能に保持された中空の両頭針と、 前記ケース 対して薬剤バイアルが押し込まれる前の状態では、 前記密閉空間の気密状 態を維持し、 前記ケースに対して薬剤バイアルが押し込まれ、 ケース底部 に向かって移動する間、 このケース内を滑動し、 前記気密状態を一旦解除 し、 前記薬剤バイアルが押し込まれてしまった状態で、 前記密閉空間を再 度、 気密状態にする遮蔽体とを備えた医療用容器において、 前記ケース内 に嵌入させられた前記薬剤バイアルの底部に当接させた状態で、 かつ前記 ケースに取り付け部を破壊することなく、 前記底部から離れられな L、状態 に前記ケースに取り付けられた吊り具を設けて形成したことを特徴とする 医療用容器。  3. A dissolving solution container having a sealed connection port, a bottomed cylindrical case having a connection pipe connected to the connection port at the bottom, and an opening provided at the bottom. A fixing jig that is held movably in the axial direction, and a port sealed with a stopper made of an elastic material is fitted into the bottom of the fixing jig, and is movable with the fixing jig. A drug vial held in the case; a hollow double-ended needle held movably in the axial direction in a sealed space formed on the case bottom side of the mouth of the drug vial; Before the medicine vial is pushed into the case, the hermetically sealed state of the sealed space is maintained, and the medicine vial is pushed into the case and slides inside the case while moving toward the case bottom. The airtight condition A medical container provided with a shield that releases the drug vial and presses the sealed space again in an airtight state in a state where the drug vial has been pushed in, wherein the bottom of the drug vial fitted in the case is provided. Medical device characterized by being provided with a hanging device attached to the case in a state of being separated from the bottom portion in a state in which the hanging member is not separated from the bottom portion without breaking the attachment portion to the case in a state where it is brought into contact with the case. container.
4. 前記薬剤バイャルの口部の栓の外側に、 この栓の抜け止め用として環 状のキャップを固定し、 このキヤップの天面開口部の縁部を前記栓の側に 折り曲げ、 この栓の天面に気密状に圧着させるとともに、 前記固定治具の 底部と前記キヤップとの間に環状の弾性部材を介在させて形成したことを 特徴とする請求項 1または 3に記載の医療用容器。 4. An annular cap is fixed to the outside of the stopper at the mouth of the drug vial to prevent the stopper from coming off, and the edge of the top opening of the cap is bent toward the stopper, and the cap is closed. 4. The medical container according to claim 1, wherein the medical container is air-tightly pressed on a top surface and formed by interposing an annular elastic member between a bottom of the fixing jig and the cap.
5. 前記ケース内に嵌入させられた前記薬剤バイアルの底部に当接させた 状態で、 かつ前記ケースに取り付け部を破壊することなく、 前記底部から 離れられない状態に前記ケースに取り付けられた吊り具を設けて形成した ことを特徴とする請求項 1または 2に記載の医療用容器。 5. A suspension attached to the case in a state in which it is in contact with the bottom of the medicine vial fitted in the case, and is not separated from the bottom without breaking the attachment portion in the case. 3. The medical container according to claim 1, wherein the medical container is formed by providing a tool.
6. 前記薬剤バイャルの口部の栓の外側に、 この栓の抜け止め用として環 状のキャップを固定し、 このキャップの天面開口部の縁部を前記栓の側に 折り曲げ、 この栓の天面に気密状に圧着させるとともに、 前記固定治具の 底部と前記キャップとの間に環状の弾性部材を介在させ、 かつ前記ケース 内に嵌入させられた前記薬剤バイアルの底部に当接させた状態で、 かつ前 記ケースに取り付け部を破壊することなく、 前記底部から離れられない状 態に前記ケースに取り付けられた吊り具を設けて形成したことを特徴とす る請求項 1に記載の医療用容器。  6. An annular cap is fixed to the outside of the stopper at the mouth of the drug vial to prevent the stopper from coming off, and the edge of the opening at the top surface of the cap is bent toward the stopper, and the cap is closed. It was air-tightly pressed on the top surface, an annular elastic member was interposed between the bottom of the fixing jig and the cap, and was brought into contact with the bottom of the medicine vial fitted in the case. The hanging member attached to the case is provided in a state in which the hanging portion is not separated from the bottom portion in a state and without destroying the attaching portion to the case. Medical container.
PCT/JP1994/000935 1993-06-28 1994-06-09 Medical container WO1995000101A1 (en)

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