JPH08238300A - Infusion container - Google Patents

Abstract

PURPOSE: To aseptically mix a drug and a dissolving soln. by thrusting the lower puncture needle of a double ended needle in the mouth part of a drug container when the cam pressing part of a vial carrier moves downwardly and rotating the double ended needle to release engagement to pierce the hermet ical seal member of the communication port of a dissolving soln. container. CONSTITUTION: When a cap 6 is pressed to move a drug container 1 downwardly, the vial carrier 2 provided to the mouth part of the drug container 1 falls along a guide 31 along with the drug container 1 without being rotated and the upper puncture needle of a double ended needle 4 is thrust in a rubber plug 11. The double ended needle 4 is engaged at the position of the engaging part of a guide capsule 3 before thrusting by an engaging arm but the double ended needle 4 is rotated at a time of thrusting by the cooperation of the cam 42 provided to the upper surface of the hub 41 of the double ended needle 4 and a cam pressing part and the engaging arm is shifted from the position of the engaging part and the engaged state is released and the downward movement of the double ended needle becomes possible and the lower puncture needle of the double ended needle 4 is thrust in the closure film 52 of the communication port 51 of a dissolving soln. container 5.

Description

Detailed Description of the Invention

[0001]

FIELD OF THE INVENTION The present invention relates to a container for infusion. More specifically, dry drug such as powder formulation and freeze-dried formulation,
The present invention relates to an infusion container for storing the dissolved solution in a separated state, aseptically mixing the dry drug and the dissolved solution in the container immediately before use, and supplying the solution as an infusion solution.

[0002]

2. Description of the Related Art Conventionally, in a medical institution such as a hospital, a dried preparation contained in a vial or the like is dissolved in a solution such as distilled water, physiological saline or glucose solution and used for infusion. At this time, the container containing the drug and the container containing the solution of the drug are connected using a connecting tool such as a double-ended needle or a connecting pipe, and the solution is transferred to the container containing the drug to transfer the drug. It is dissolved. However, this operation is complicated and time-consuming, and since the operation of making a connection hole in the container containing the drug in the open air, the drug inside may be contaminated. Therefore, in order to solve the above problems,
Japanese Patent Publication No. Sho 61-501129 and Shokai No. Sho 63-135
As shown in Japanese Patent Laid-Open No. 642 and Japanese Patent Laid-Open No. 2-1277, a container containing a drug is connected in series to a container containing a solution of the drug, and these two containers are sterilized during use. An infusion container adapted to communicate with each other has been proposed.

The one disclosed in Japanese Patent Publication No. 61-501129 has a capsule containing a medicine container and a dissolution liquid container containing a dissolution liquid connected by a tube, and is provided in the tube. The drug container and the solution container are communicated by the communicating means, and the drug and the solution are aseptically mixed. Also, the actual development 63-13
Japanese Patent No. 5642 discloses that a cylindrical support ring that is appropriately removable is provided at a seal portion of a mouth of a dissolution liquid container, and a double-ended needle is attached to the support ring so as to be vertically slidable. When the needle is slid downward, the lower needle body pierces the seal portion at the mouth of the solution container. In addition, JP-A-2-127
No. 7 discloses that a hollow puncture needle having a hub in the middle and blade edges at both ends is interposed between a drug container and a solution container, and the drug container is first pierced by the puncture needle, and then An infusion solution configured to pierce the dissolution liquid container to ensure reliable and easy communication between the drug container and the dissolution liquid container, and to allow aseptic mixing of the drug and the dissolution liquid after communication. It is a container for.

Each of these infusion containers directly takes in a vial, which is a general distribution form of a dry drug,
Since it is integrated, it is highly versatile. However, for example, the infusion container disclosed in JP-A-61-501129 has a large number of parts, and it takes time to fold the breaking member by hand to open the passage, and the breaking member is incompletely broken. In such a case, the solution is difficult to pass smoothly, and it has a drawback that it takes time to dissolve it. Also, the actual exploitation 63
Although the infusion container of Japanese Patent No. 135642 has a small number of parts and is relatively easy to operate, it requires a relatively large force to communicate with each other, and after mixing the drug and the solution, the support ring and the double-ended needle are removed to dissolve the solution. Since it is necessary to invert the container and connect an infusion set etc. to the seal part at the mouth of the dissolution liquid container after removing the double-ended needle, the operation is complicated, and the mixed chemical solution may leak when the double-ended needle is removed. There are some drawbacks, such as the presence of mist. Further, in the infusion container disclosed in JP-A No. 2-1277, the communication between the drug container and the dissolution container is simplified as compared with JP-A-61-501129, but the number of parts is large as a whole. It has a drawback that parts such as braking means that regulate the communication order are complicated. Furthermore, since the part that serves as the braking means operates by being bent and deformed by pressure from the outside, the type of material of the part, temperature change during use, force input when the user performs communication operation, etc. There is a concern that the parts will crack and will not be communicated.

[0005]

DISCLOSURE OF THE INVENTION The present invention has been made in view of the above situation, and is easy to operate and requires no trouble.
It is an object of the present invention to provide an infusion container capable of aseptically mixing a drug and a solution without the risk of leakage of the mixed drug solution, the number of parts is small, and the shape of parts is simple. Another object of the present invention is to provide an infusion container having a reliable communication sequence regulating means.

[0006]

In order to solve the above problems, the present invention is capable of puncturing with a drug container whose mouth is sealed by a stopper that can be pierced by a puncture needle, a drug solution outlet and a puncture needle. A solution container made of a synthetic resin that is press-deformable and has a communication port with a drug container sealed by a sealing member at both ends thereof, and is interposed between the mouth part of the drug container and the communication port of the solution container. Also, a double-ended needle consisting of an upper puncture needle, a lower puncture needle, and a hub, a vial carrier that holds the drug container and moves the drug container downward, and a connection between the open end and the communication port of the dissolution liquid container A guide capsule that has an end and a locking portion that locks the double-ended needle, accommodates the vial carrier and the double-ended needle, and guides the downward movement of the vial carrier, and seals the open end of the guide capsule. Accommodates part of the drug container with A pair of cams is formed on the upper surface of the hub of the double-ended needle in an axially symmetrical manner, and the vial carrier engages with the cam on its outer wall to hold the double-ended needle. A pair of cam pressing portions for rotating is formed, and when the drug container is moved downward, the upper puncture needle of the double-ended needle pierces the mouth of the drug container and the double-ended needle rotates. By releasing the locked state with the guide capsule, further moving downward together with the drug container, by piercing the sealing member of the communication port of the dissolution liquid container by the lower puncture needle of the double-ended needle,
An infusion container characterized in that the drug container and the solution container are communicated with each other is adopted. The communication port with the drug container is preferably closed with a closing film. Further, the cam on the upper surface of the hub of the double-ended needle may be formed in an arc-shaped plate. Furthermore, the cap may be provided with suspending means.

[0007]

In FIG. 1 and FIG. 2, the guide receiving portion 22 of the vial carrier 2 holding the drug container 1 is fitted in the guide 31 provided on the inner wall of the guide capsule 3.
The double-ended needle 4 is locked in advance by a locking portion 32 provided on the inner wall of the guide capsule 3. In this configuration, for example, when the cap 6 is pushed and the drug container 1 is pushed down together with the vial carrier 2, the vial carrier 2 moves downward to reach the double-ended needle 4, and first, the rubber stopper 11 at the mouth of the drug container 4 is double-ended. 4 is pierced by the upper puncture needle 43.
The double-ended needle 4 is engaged with a cam 42 provided on the upper surface of the hub 41 thereof and a cam pressing portion 21 provided on the vial carrier 2, and the vial carrier 2 has its guide receiving portion 22.
Moves downward along the guide 31 of the guide capsule 3, so that the double-ended needle 4 does not move downward at the position of the locking portion 32 with the downward movement of the vial carrier 2 that holds the drug container 1 during piercing. Rotate at an angle, for example 45 °. Then, the hub 41 of the double-ended needle 4 comes out of the locking portion 32 and can be moved downward, the drug container 1 is further pushed down, the double-ended needle 4 moves downward together with the vial carrier 2 and the drug container 1, and the solution is dissolved. For example, the closing film 52 of the sealing member provided in the communication port 51 of the container 5 is pierced by the lower puncture needle 44 of the double-ended needle 4. In this way, by moving the drug container downward, the communication operation between the drug container and the dissolution liquid container is easily achieved, and the communication order is reliably regulated. That is, the rubber stopper 11 at the mouth of the drug container 1 is pierced first, and the communication port 51 of the solution container 5 is pierced later.

The terminology used in this specification, such as the vertical direction, indicates the direction when the infusion container is in a normal use state, and is merely to facilitate understanding of the structure of the infusion container. is there.

[0009]

Embodiments of the present invention will now be described with reference to the drawings. 1 is a partial sectional front view of an essential part of an infusion container of the present invention, FIG. 2 is a partial sectional side view of the essential part of FIG. 1, FIG. 3 is a plan view of the guide capsule of FIG. 1, and FIG. 1 is a partial sectional front view of the vial carrier of FIG. 1, FIG. 5 is a plan view of the vial carrier of FIG. 4, FIG. 6 is a vertical sectional view of another embodiment of the vial carrier, and FIG. 7 is of the vial carrier of FIG. FIG. 8 is a bottom view, FIG. 8 is a front view of the double-ended needle of FIG. 1, FIG. 9 is a plan view of the double-ended needle of FIG. 8, and FIGS. 10 and 11 are explanatory views for explaining the operation of the double-ended needle of FIG. 1 and the vial carrier. .

As shown in FIGS. 1 and 2, the infusion container of the present invention comprises a drug container 1, a solution container 5, a double-ended needle 4, a vial carrier 2, a guide capsule 3 and a cap 6. The guide capsule 3 is connected at its connecting end to the neck portion 51 of the dissolution liquid container 5, and its open end is at the cap 6
It is sealed by. And the neck portion 51 of the dissolution liquid container 5
A communication port 51 is provided in the. Vial carrier 2
The drug container 1 held by the mouth portion downward is housed inside the cap 6 and the guide capsule 3. The double-ended needle 4 is housed in the guide capsule 3 and is locked by a locking portion 32 provided on the inner wall of the guide capsule 3.
It is arranged between the rubber stopper 11 at the mouth portion of and the communication port 51 of the solution container 5. Therefore, when the cap 6 is pushed down, the drug container 1 is lowered together with the vial carrier 2, the upper puncture needle 43 of the double-ended needle 4 pierces the rubber stopper 11 at the mouth of the drug container 1, and the double-ended needle 4 Is rotated by a predetermined angle at the locking position to escape from the locking portion 32, and further descends together with the drug container 1 and the vial carrier 2, and the closing membrane 52 of the communication port 51 of the dissolution liquid container 5 by the lower puncture needle 44 thereof. The two containers are pierced with each other to communicate with each other to allow the drug contained in the container and the solution to be mixed.

As the drug container 1, a commercially available one made of glass or plastic can be used, and as shown in FIG. 1, its mouth has a self-sealing property such as a rubber stopper 11 which can be pierced by a double-ended needle 4. It is sealed with a sealing member. In order to fix the mouth portion in a more liquid-tight manner, the rubber stopper 11 may be further wound by a cover member made of a material such as aluminum.
It should be noted that although a dry preparation such as a powder preparation or a freeze-dried preparation is contained in the drug container 1, it is omitted in the figure.

The vial carrier 2 that holds the drug container 1 as shown in FIG. 1 and functions as an auxiliary tool for moving the drug container 1 downward is usually polyethylene, polypropylene, polyester, polyvinyl chloride, polycarbonate, ABS. As shown in FIGS. 4 to 5, it is a short tubular member that is formed of a synthetic resin such as resin and is attached to the mouth of the drug container 1 described later, and has a cam pressing portion 21 and a guide receiving portion on its outer wall. The part 22 is formed. A through hole 25 is formed in the bottom of the double-ended needle 4 at a position where the upper puncture needle 43 is punctured.

The cam pressing portion 21 has a function of engaging a cam 42 formed on the upper surface of the hub 41 of the double-ended needle 4 to press it, and rotate the double-ended needle 4 at the locking position. In the figure, the cam pressing portion 21 is formed on the outer wall of the vial carrier 2 as a pair of ribs symmetrical with respect to the central axis. A pair of guide receiving portions 22 each having an axially symmetrical shape are formed at a position deviated from the cam pressing portion 21 by 90 °. The guide receiving portion 22 is fitted in a guide 31 formed on the inner wall of a guide capsule 3 described later, restrains the vial carrier 2 so that it cannot rotate, and only allows downward movement along the guide 31.

In order to mount the drug container 1 on the vial carrier 2 so as not to fall off, a plurality of slits 23 may be provided on the upper side wall thereof, or an annular undercut may be provided on the upper inner wall thereof. In FIG. 5, three slits 23 are provided. By providing these, it is possible to use the medicine container 1 having a slightly different opening diameter. The vial carrier 2 has a cam pressing portion 21 and a guide receiving portion 22, and the shape is not limited to this as long as it holds the drug container 1. For example, as shown in FIGS. A pair of arms 26 are axially symmetrically formed on a short tubular member attached to the mouth of the arm, a cam pressing portion 21 is provided on the outer wall of the short tubular member, and a guide receiving member is provided at the lower end of the arm 26. A configuration in which the portion 22 is provided with a claw 27 for holding the bottom portion of the medicine container 1 on the upper end of the arm 26 is also suitably adopted.

A vial carrier 2 holding a drug container 1
Part of it is housed in the guide capsule 3 together with the double-ended needle 4. The guide capsule 3 is usually a vial carrier 2
1 is a substantially cylindrical member made of a synthetic resin similar to
As shown in 2, it has a release end and a coupling end at both ends. An annular projection 33 is formed on the outer wall of the open end side,
A cap 6 is airtightly and slidably connected. On the other hand, a coupling portion 34 for coupling with a neck portion 54 of the dissolution liquid container 5 described later is provided on the coupling end side in an annular shape, and the inner wall of the guide capsule 3 runs longitudinally from the coupling end to the release end. The pair of guides 31 are formed in axial symmetry.

This guide 31 is a part of the vial carrier 2
It is for fitting the pair of guide receiving portions 22 and moving the vial carrier 2 downward without rotating it. As shown in FIG. 3, the sliding groove 3 is formed by two vertical ribs 311 and 312.
13 are formed, and one pair is formed axially symmetrically.
In the figure, the guide 31 and the guide receiving portion 22 are formed as a pair due to the mutual fitting relationship, but a plurality of each may be formed. Furthermore, the guide 31 may be formed with a rib, and the guide receiving portion 22 may be formed with a groove that fits with the guide 31. In short, mutual fitting shapes and the like are not limited to this as long as the vial carrier 2 is fitted so as to move downward along the guide without rotating.

A locking portion 32 for locking a double-ended needle 4 described later is provided on the inner wall of the guide capsule 3 on the coupling end side.
The locking portion 32 is configured so that the double-ended needle 4 can be moved out of the double-ended needle 4 by rotating the double-ended needle 4 by a predetermined angle, and the double-ended needle 4 can be moved downward. That is, as shown in FIG.
It is formed as a pair of axially symmetric stepped portions on a concentric circle. More preferably, the shape of the inner wall of the joint end side is formed in a taper shape in which the diameter increases from the joint end toward the open end. The shape of the inner wall on the coupling end side does not necessarily have to be a tapered shape, but with such a configuration,
When the double-ended needle 4 escapes from the hook portion 32 and moves downward, it is convenient because it is gradually lowered while being pressed against the inner wall with a considerable pressure.

The connecting portion 34 is a neck portion 5 of the dissolution liquid container 5 described later.
4 is a portion that is liquid-tightly coupled to the nozzle 4 and is welded in the figure. This connection is not limited to welding, but may be, for example, screwing or fitting, and the guide capsule and the solution container may be integrally formed.

The double-ended needle 4 used as the communication means is shown in FIG.
It is placed between the drug container 1 and the solution container 5 as shown in FIG. 1, and is usually made of stainless steel (SUS304 is preferable).
Alternatively, a synthetic resin canula and a synthetic resin hub are preferable. However, from the viewpoint of disposal and integral molding, those made of synthetic resin, for example, those made of high-density polyethylene, ABS resin, polycarbonate, etc. are preferably adopted. As shown in FIGS. 8 to 9, the double-ended needle 4 is an upper puncture needle 43 that pierces the rubber stopper 11 of the mouth of the drug container 1 held by the vial carrier 2 and descended together with the vial carrier 2.
And a lower puncture needle 44 that pierces the closing membrane 52 of the communication port 51 of the dissolution liquid container 5, and an upper puncture needle 43 and a lower puncture needle 44.
And a hub 41 as a braking unit that regulates the communication order.

A pair of cams 42 are concentrically arranged on the outer periphery of the upper surface of the hub 41 so as to be axially symmetric, and engage with the cam pressing portion 21 of the vial carrier 2. Therefore, when the vial carrier 2 descends, the cam 42 comes into contact with the cam pressing portion 21 and is pressed by the relationship that the vial carrier 2 cannot rotate, thereby giving the double-ended needle 4 a rotational movement. In the figure, the cam 42 is formed as an arcuate plate on the outer periphery of the upper surface of the hub 41, but the shape of the cam is not limited to this. For example, the cam is formed as a spiral step on the outer peripheral side wall of the hub 41. May be. Further, on the outer periphery of the hub 41, a pair of projecting locking arms 45 are formed concentrically and axially symmetrically so as to be locked by the locking portion 32 of the guide capsule 3. The locking arms 45 are formed in a pair due to the relationship with the locking portion 32. Reference numeral 46 denotes a chemical liquid passage that penetrates the central portion of the double-ended needle 4, and two chemical liquid passages are formed in the figure, but the number of chemical liquid passages may be one.

The solution container 5 is made of a relatively soft synthetic resin and is deformable by pressing, and is generally made of a synthetic resin such as polyethylene, polypropylene, ethylene vinyl acetate copolymer, polyvinyl chloride or polyester. . As shown in FIG. 1, a communication port 51 is provided at the upper end of the solution container 5.
Is formed, and the chemical solution outlet 53 is formed at the lower end. The communication port 51 is sealed with a sealing member that can be pierced by a puncture needle, and is sealed with, for example, a closing film 52 in the figure. This closing film 52 is used for the solution container 5
It is formed as a thin film of a synthetic resin similar to the above with a thickness of 0.1 to 0.8 mm, but the sealing member is not limited to this.
For example, a rubber elastic body such as a rubber plug is also preferably used. It is preferable that the drug solution outlet is equipped with a sealing member formed of a rubber elastic body such as a rubber plug so that it can be connected to an infusion set or the like. Note that a solution such as distilled water, physiological saline, or glucose solution is contained in the solution container 5, but it is omitted in the figure.

As shown in FIG. 1, the cap 6 hermetically seals the open end of the guide capsule 3 and holds and holds a part of the medicine container 1. The cap 6 is usually made of the same synthetic resin as the guide capsule 3 and is a cylinder. Formed into a shape. An O-ring 61 formed of a rubber elastic body is attached to the inner wall of the lower end of the cap 6 so as to be airtightly coupled to the guide capsule 3 and slidable, and provided on the outer wall of the open end side of the guide capsule 3. Is engaged with the annular projection 33. The inner wall of the upper surface of the cap 6 is in contact with the bottom of the drug container 1, and the drug container 1 is moved downward by pushing down the cap 6. In the figure, the cap 6 and the guide capsule 3 are connected with an O-ring 61 interposed therebetween, but the connection is not limited to this as long as it is an airtight and slidable connection, and for example, it may be connected by screwing. Good. In the case of screwing, the medicine container 1 moves downward by rotating the cap 6.

The double-ended needle 4 is pierced through the mouth of the medicine container 1 to cut the rubber stopper 11 of the medicine container 1, and the cut pieces are mixed into the medicine container 1.
In order to avoid the generation of foreign matter due to so-called coring, it is more preferable to provide a small protrusion, for example, at the center of the inner wall of the upper surface of the cap 6 so that the medicine container 1 rotates together with the double-ended needle during piercing. Furthermore, if a suspending means 62 is provided on the outer wall of the upper surface of the cap 6 as shown in FIG. 1, it is convenient because it can be suspended on a hanger when the mixed drug solution is taken out from the drug solution outlet using an infusion set or the like. is there.

Next, the state in which the infusion container of the present invention is communicated with the double-ended needle will be described in detail with reference to FIGS. 1, 10, and 11. When the cap 6 is pushed to move the drug container 1 downward, the vial carrier 2 attached to the mouth of the drug container 1 has the guide receiving portion 22 of the vial carrier 2 and the guide 31 of the guide capsule 3 fitted together. It descends along the guide 31 together with the medicine container 1 without rotating (FIG. 1).
Then, the rubber stopper 11 at the mouth of the drug container 1 is pierced by the upper puncture needle 43 of the double-ended needle 4. The double-ended needle 4 is hooked by the locking arm 45 at the position of the locking portion 32 of the guide capsule 3 before the piercing, but at the time of piercing, the cam 42 provided on the upper surface of the hub 41 of the double-ended needle 4 and the vial. The double-ended needle 4 rotates in cooperation with the cam pressing portion 21 provided on the carrier 2, the locking arm 45 is disengaged from the position of the locking portion 32 and the locked state is released, and the downward movement of the double-ended needle 4 is prevented. It becomes possible (Fig. 1
0). When the drug container 1 is further moved by pushing the cap 6 after the piercing, the double-ended needle 4 moves downward together with the vial carrier 2 and the drug container 1, and the lower puncture needle 44 closes the closing membrane 52 of the communication port 51 of the dissolution liquid container 5. Is pierced (Fig. 11).

In this way, when the drug container 1 and the solution container 5 are communicated with each other via the double-ended needle 4, the solution container 5 is then pushed upward to allow the solution to flow into the drug container 1. Thus, a drug such as a powder formulation can be dissolved into a drug solution. Next, the hanging means 62 provided on the cap 6 is used to hang it on a hanger or the like, and the solution container 5 is pumped to return the drug solution in the drug container 1 back into the solution container 5 to remove the drug solution outlet 53.
When combined with an infusion set or the like, it can be used for infusion therapy.

Regarding the shape of the infusion container of the present invention, for example, in the above-mentioned embodiment, the double-ended needle 4 is provided with the cam 42 and the vial carrier 2 is provided with the cam pressing portion 21, but the vial carrier 2 is provided with the cam. However, the present invention is not limited to the embodiment described above, such as the structure in which the double-ended needle 4 is provided with the cam pressing portion, and various changes and modifications are possible.

[0027]

As described above, by adopting the infusion container of the present invention, the mixing operation is simple and labor-free, the number of parts is small, the shape of parts is simple, and the drug and solution are aseptically It is possible to provide an infusion container in which the above can be mixed. Furthermore, since the double-ended needle is reliably pierced into the drug container prior to piercing into the solution container, the drug solution does not leak into the guide capsule. Furthermore, when the double-ended needle is pierced into the mouth-sealing member of the drug container, the hub that is the braking means does not bend and deform, so that cracks are less likely to occur in the parts and even if the user is different Communication operation can be performed.

[Brief description of drawings]

FIG. 1 is a sectional front view of a main part showing an embodiment of an infusion container of the present invention.

FIG. 2 is a partial cross-sectional side view showing a main part of FIG.

FIG. 3 is a plan view of the guide capsule of FIG.

4 is a partial cross-sectional front view of the vial carrier of FIG.

5 is a plan view of the vial carrier of FIG. 4. FIG.

FIG. 6 is a vertical sectional view showing another embodiment of the vial carrier.

FIG. 7 is a bottom view of the vial carrier of FIG.

8 is a front view of the double-ended needle of FIG. 1. FIG.

9 is a plan view of the double-ended needle of FIG. 8. FIG.

FIG. 10 is an explanatory diagram for explaining the operation of the double-ended needle and the vial carrier of FIG. 1.

FIG. 11 is an explanatory diagram for explaining the operation of the double-ended needle and the vial carrier of FIG. 1.

[Explanation of symbols]

 1. Drug container 2. Vial carrier 3. Guide capsule 4. Double-ended needle 5. Dissolution container 6. Cap 11. Rubber stopper 21. Cam pressing part 22. Guide receiving part 31. Guide 32. Locking part 33. Annular protrusion 34. Coupling part 41. Hub 42. Cam 43. Upper puncture needle 44. Lower puncture needle 45. Locking arm 51. Communication port 52. Closure membrane 53. Chemical solution outlet 54. Neck

Claims (4)

[Claims] 1. A drug container whose mouth is sealed by a stopper that can be pierced by a puncture needle, and a communication port between a drug solution outlet and a drug container which is sealed by a sealing member that can be punctured by a puncture needle. And a solution container made of a synthetic resin that can be deformed by pressure, and a double-ended needle consisting of an upper puncture needle, a lower puncture needle, and a hub, which is interposed between the mouth of the drug container and the communication port of the solution container. A vial carrier for holding the drug container and moving the drug container downward, a connecting end between an open end and a communication port of the dissolution liquid container, and a locking portion for locking the double-ended needle. A guide capsule for accommodating the vial carrier and the double-ended needle to guide downward movement of the vial carrier; and a cap for sealing the open end of the guide capsule and accommodating and holding a part of the drug container. Is composed of the double-ended needle Has a pair of cams formed axially symmetrically on the upper surface of its hub, and the vial carrier has a pair of cam pressing portions formed on its outer wall for engaging the cams and rotating the double-ended needle. When the drug container is moved downward, the mouth part of the drug container is pierced by the upper puncture needle of the double-ended needle, and the double-ended needle rotates to release the locked state with the guide capsule, By moving downward with the container, and by piercing the sealing member of the communication port of the dissolution liquid container with the lower puncture needle of the double-ended needle,
An infusion container characterized in that a drug container and a solution container are communicated with each other. 2. The infusion container according to claim 1, wherein the communication port with the drug container is a dissolution liquid container closed with a closing membrane. 3. The infusion container according to claim 1, wherein the cam on the upper surface of the hub of the double-ended needle is formed into an arc-shaped plate. 4. The infusion container according to claim 1, wherein the cap is provided with suspending means.