UY38890A - Procedimiento para preparar 5-(fluoro-4-imino-3-metil)-1-tosil-3,4-dihidropirimidin-(1h)-ona y derivados del compuesto - Google Patents

Procedimiento para preparar 5-(fluoro-4-imino-3-metil)-1-tosil-3,4-dihidropirimidin-(1h)-ona y derivados del compuesto

Info

Publication number
UY38890A
UY38890A UY0001038890A UY38890A UY38890A UY 38890 A UY38890 A UY 38890A UY 0001038890 A UY0001038890 A UY 0001038890A UY 38890 A UY38890 A UY 38890A UY 38890 A UY38890 A UY 38890A
Authority
UY
Uruguay
Prior art keywords
preparing
tosil
dihydropyrimidin
imino
fluoro
Prior art date
Application number
UY0001038890A
Other languages
English (en)
Inventor
Gal Suez
Samaa Alasibi
Yaakov Mines
Original Assignee
Adama Makhteshim Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adama Makhteshim Ltd filed Critical Adama Makhteshim Ltd
Publication of UY38890A publication Critical patent/UY38890A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C273/00—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C273/18—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas
    • C07C273/1854—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas by reactions not involving the formation of the N-C(O)-N- moiety
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C273/00—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C273/18—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas
    • C07C273/1854—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas by reactions not involving the formation of the N-C(O)-N- moiety
    • C07C273/1863—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas by reactions not involving the formation of the N-C(O)-N- moiety from urea

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Agronomy & Crop Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)

Abstract

La presente invención proporciona un proceso para preparar un compuesto que tiene la fórmula (I):(I) en la que R es alquilo o alquilarilo; cada uno de X1, X2, X3, X4 y X5 es, independientemente, H, alquilo, alquenilo, alquinilo, alcoxi, haloalquilo, haloalcoxi, alquiltio, haloalquiltio, amino, aquilamino, dialquilamino, alcoxicarbonilo, alquil carbonilo, hidroxialquilo, éster, ácido, halógeno, --SH, -OH, -NH2, -NO2, -CN o CF3; Y es O o S; y Z es un halógeno.
UY0001038890A 2019-09-23 2020-09-23 Procedimiento para preparar 5-(fluoro-4-imino-3-metil)-1-tosil-3,4-dihidropirimidin-(1h)-ona y derivados del compuesto UY38890A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201962904482P 2019-09-23 2019-09-23

Publications (1)

Publication Number Publication Date
UY38890A true UY38890A (es) 2021-04-30

Family

ID=72744814

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001038890A UY38890A (es) 2019-09-23 2020-09-23 Procedimiento para preparar 5-(fluoro-4-imino-3-metil)-1-tosil-3,4-dihidropirimidin-(1h)-ona y derivados del compuesto

Country Status (9)

Country Link
US (1) US20230143040A1 (es)
EP (1) EP4034529A1 (es)
CN (1) CN114599639A (es)
AR (1) AR120035A1 (es)
BR (1) BR112022005464A2 (es)
IL (1) IL291384A (es)
TW (1) TWI808347B (es)
UY (1) UY38890A (es)
WO (1) WO2021059160A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR127068A1 (es) 2021-09-15 2023-12-13 Adama Makhteshim Ltd Procedimiento para preparar 5-fluoro-4-imino-3-metil-1(tolueno-4-sulfonil)-3,4-dihidro-1h-pirimidin-2-ona
AR128692A1 (es) 2022-03-03 2024-06-05 Adama Makhteshim Ltd Combinaciones, mezclas y composiciones fungicidas y usos de las mismas
WO2023228148A1 (en) 2022-05-26 2023-11-30 Adama Makhteshim Ltd. Fungicidal combinations, mixtures and compositions and uses thereof
WO2024028812A1 (en) 2022-08-03 2024-02-08 Adama Makhteshim Ltd. 5-fluoro-4-imino-3-methyl-1-tosyl-3,4-dihydropyrimidin-2(1h)-one for fungicide-resistant fungus
WO2024184859A1 (en) 2023-03-09 2024-09-12 Conese Salvatore Fungicidal combinations, mixtures and compositions and uses thereof
WO2024189563A1 (en) 2023-03-14 2024-09-19 Adama Makhteshim Ltd. Liquid compositions containing 5-(fluoro-4-imino-3-methyl)-1-tosyl-3,4 dihydropyrimidine-(1h)-one and derivatives thereof and a uv absorber
WO2024194833A1 (en) 2023-03-23 2024-09-26 Adama Makhteshim Ltd. Process for preparing 5-fluoro-4-imino-3-methyl-1-(toluene-4-sulfonyl)-3,4-dihydro-1h-pyrimidin-2-one

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2774760A (en) * 1953-10-14 1956-12-18 Lilly Co Eli Process for production of pyrimidines
JPS58162579A (ja) 1982-03-20 1983-09-27 Yodogawa Seiyaku Kk シトシンの製造方法
JPS58185569A (ja) 1982-04-24 1983-10-29 Yodogawa Seiyaku Kk シトシン−５−カルボン酸の製造方法
CN101597264A (zh) 2008-06-03 2009-12-09 上海普渡生化科技有限公司 一种合成胞嘧啶的方法
CR20160343A (es) 2013-12-31 2016-12-14 Adama Makhteshim Ltd 5-fluor-4-imino-3-(alquil/alquilo sustituido)-1-(arilsulfonil)-3,4-dihidropirimidin-2 (1h)-ona y los procesos para su preparación
CN103992278B (zh) 2014-05-23 2016-07-06 南阳师范学院 一种胞嘧啶的合成方法

Also Published As

Publication number Publication date
IL291384A (en) 2022-05-01
TW202112236A (zh) 2021-04-01
BR112022005464A2 (pt) 2022-08-16
EP4034529A1 (en) 2022-08-03
AR120035A1 (es) 2022-01-26
CN114599639A (zh) 2022-06-07
TWI808347B (zh) 2023-07-11
WO2021059160A1 (en) 2021-04-01
US20230143040A1 (en) 2023-05-11

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