UY37997A - Agentes antivirales contra la hepatitis b - Google Patents
Agentes antivirales contra la hepatitis bInfo
- Publication number
- UY37997A UY37997A UY0001037997A UY37997A UY37997A UY 37997 A UY37997 A UY 37997A UY 0001037997 A UY0001037997 A UY 0001037997A UY 37997 A UY37997 A UY 37997A UY 37997 A UY37997 A UY 37997A
- Authority
- UY
- Uruguay
- Prior art keywords
- antiviral agents
- hbv
- present
- hepatitis
- compounds
- Prior art date
Links
- 239000003443 antiviral agent Substances 0.000 title abstract 2
- 208000006454 hepatitis Diseases 0.000 title 1
- 231100000283 hepatitis Toxicity 0.000 title 1
- 241000700721 Hepatitis B virus Species 0.000 abstract 5
- 150000001875 compounds Chemical class 0.000 abstract 3
- 208000015181 infectious disease Diseases 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/20—Spiro-condensed systems
Abstract
La presente invención revela compuestos de Fórmula (I), o sales de uso farmacéutico aceptable de los mismos: los cuales inhiben la(s) proteína(s) codificada(s) por el virus de la hepatitis B (HBV) o interfieren con el funcionamiento del ciclo de vida del HBV del virus de la hepatitis B y que también son útiles como agentes antivirales. La presente invención se relaciona además a las composiciones farmacéuticas que comprende a los compuestos mencionados anteriormente para la administración a un sujeto que padece de infección por HBV. La invención también se relaciona con los métodos para el tratamiento de una infección por HBV en un sujeto mediante la administración de una composición farmacéutica que comprende los compuestos de la presente invención.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762595271P | 2017-12-06 | 2017-12-06 | |
US201862674209P | 2018-05-21 | 2018-05-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
UY37997A true UY37997A (es) | 2019-04-30 |
Family
ID=66437163
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UY0001037997A UY37997A (es) | 2017-12-06 | 2018-12-06 | Agentes antivirales contra la hepatitis b |
Country Status (4)
Country | Link |
---|---|
US (1) | US10428070B2 (es) |
TW (1) | TW201927789A (es) |
UY (1) | UY37997A (es) |
WO (1) | WO2019113173A1 (es) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2020247444A1 (en) * | 2019-06-03 | 2020-12-10 | Enanta Pharmaceuticals, Inc, | Hepatitis b antiviral agents |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
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EP3148986A4 (en) | 2014-05-27 | 2018-01-10 | Navigen, Inc. | Arf6 inhibitors and methods of synthesis and use thereof |
WO2016183266A1 (en) | 2015-05-13 | 2016-11-17 | Enanta Pharmaceuticals, Inc. | Ehpatitis b antiviral agents |
WO2017011552A1 (en) | 2015-07-13 | 2017-01-19 | Enanta Pharmaceuticals, Inc. | Hepatitis b antiviral agents |
KR102398439B1 (ko) | 2016-03-07 | 2022-05-16 | 이난타 파마슈티칼스, 인코포레이티드 | B형 간염 항바이러스제 |
US10189846B2 (en) | 2016-06-10 | 2019-01-29 | Enanta Pharmaceuticals, Inc. | Hepatitis B antiviral agents |
EP3675637A4 (en) | 2017-08-28 | 2021-05-19 | Enanta Pharmaceuticals, Inc. | ANTIVIRAL AGENTS AGAINST HEPATITIS B |
WO2019113175A1 (en) * | 2017-12-06 | 2019-06-13 | Enanta Pharmaceuticals, Inc. | Hepatitis b antiviral agents |
US11058678B2 (en) | 2018-01-22 | 2021-07-13 | Enanta Pharmaceuticals, Inc. | Substituted heterocycles as antiviral agents |
US10729688B2 (en) | 2018-03-29 | 2020-08-04 | Enanta Pharmaceuticals, Inc. | Hepatitis B antiviral agents |
AU2019342750A1 (en) | 2018-09-21 | 2021-04-08 | Enanta Pharmaceuticals, Inc. | Functionalized heterocycles as antiviral agents |
AU2019385477A1 (en) | 2018-11-21 | 2021-06-10 | Enanta Pharmaceuticals, Inc. | Functionalized heterocycles as antiviral agents |
US11760755B2 (en) | 2019-06-04 | 2023-09-19 | Enanta Pharmaceuticals, Inc. | Hepatitis B antiviral agents |
US11472808B2 (en) | 2019-06-04 | 2022-10-18 | Enanta Pharmaceuticals, Inc. | Substituted pyrrolo[1,2-c]pyrimidines as hepatitis B antiviral agents |
US11738019B2 (en) | 2019-07-11 | 2023-08-29 | Enanta Pharmaceuticals, Inc. | Substituted heterocycles as antiviral agents |
WO2021031997A1 (zh) * | 2019-08-16 | 2021-02-25 | 西藏天晟泰丰药业有限公司 | 二氢嘧啶衍生物及其用途 |
WO2021055425A2 (en) | 2019-09-17 | 2021-03-25 | Enanta Pharmaceuticals, Inc. | Functionalized heterocycles as antiviral agents |
WO2021188414A1 (en) | 2020-03-16 | 2021-09-23 | Enanta Pharmaceuticals, Inc. | Functionalized heterocyclic compounds as antiviral agents |
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-
2018
- 2018-12-05 WO PCT/US2018/064016 patent/WO2019113173A1/en active Application Filing
- 2018-12-05 US US16/210,472 patent/US10428070B2/en active Active
- 2018-12-05 TW TW107143619A patent/TW201927789A/zh unknown
- 2018-12-06 UY UY0001037997A patent/UY37997A/es not_active Application Discontinuation
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2020247444A1 (en) * | 2019-06-03 | 2020-12-10 | Enanta Pharmaceuticals, Inc, | Hepatitis b antiviral agents |
Also Published As
Publication number | Publication date |
---|---|
US10428070B2 (en) | 2019-10-01 |
WO2019113173A1 (en) | 2019-06-13 |
US20190177320A1 (en) | 2019-06-13 |
TW201927789A (zh) | 2019-07-16 |
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