UY37139A - Monotartrato de vinorelbina y su uso farmacéutico - Google Patents

Monotartrato de vinorelbina y su uso farmacéutico

Info

Publication number
UY37139A
UY37139A UY0001037139A UY37139A UY37139A UY 37139 A UY37139 A UY 37139A UY 0001037139 A UY0001037139 A UY 0001037139A UY 37139 A UY37139 A UY 37139A UY 37139 A UY37139 A UY 37139A
Authority
UY
Uruguay
Prior art keywords
monotartrate
vinorelbin
pharmaceutical use
crystalline
cancer
Prior art date
Application number
UY0001037139A
Other languages
English (en)
Inventor
Vladimir Matha
Christian Schickaneder
Oleksandr Zabudkin
Viktor Matviyenko
Iaroslav Matviienko
Volodymyr Sypchenko
Original Assignee
Synbias Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synbias Pharma Ag filed Critical Synbias Pharma Ag
Publication of UY37139A publication Critical patent/UY37139A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La presente invención se dirige al monotartrato de vinorelbina cristalino y su uso para la prevención y el tratamiento del cáncer,particularmente el cáncer de pulmón no microcítico o el cáncer de mama. La presente invención también se refiere a un método correspondiente para la fabricación de monotartrato de vinorelbina cristalino.
UY0001037139A 2016-03-09 2017-03-01 Monotartrato de vinorelbina y su uso farmacéutico UY37139A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2016/055040 WO2017152972A1 (en) 2016-03-09 2016-03-09 Vinorelbine monotartrate and its pharmaceutical use

Publications (1)

Publication Number Publication Date
UY37139A true UY37139A (es) 2017-10-31

Family

ID=55521706

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001037139A UY37139A (es) 2016-03-09 2017-03-01 Monotartrato de vinorelbina y su uso farmacéutico

Country Status (11)

Country Link
US (1) US20190092792A1 (es)
EP (1) EP3426665A1 (es)
JP (1) JP2019508436A (es)
CN (1) CN108779129A (es)
AR (1) AR107829A1 (es)
BR (1) BR112018067637A2 (es)
CA (1) CA3014473A1 (es)
RU (1) RU2730521C2 (es)
TW (1) TW201734023A (es)
UY (1) UY37139A (es)
WO (1) WO2017152972A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115611927A (zh) * 2020-01-06 2023-01-17 刘力 长春抗肿瘤药物的新化合物
CN114621258A (zh) * 2022-04-08 2022-06-14 海南长春花药业有限公司 一种酒石酸长春瑞滨的纯化方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2707988B1 (fr) * 1993-07-21 1995-10-13 Pf Medicament Nouveaux dérivés antimitotiques des alcaloïdes binaires du catharantus rosesus, leur procédé de préparation et les compositions pharmaceutiques les comprenant.
US6627646B2 (en) * 2001-07-17 2003-09-30 Sepracor Inc. Norastemizole polymorphs
DE60331920D1 (de) 2002-05-31 2010-05-12 Rp Scherer Technologies Llc Orale pharmazeutische zusammensetzung für weichkapseln mit vinorelbin und behandlungsverfahren
CN1437942A (zh) * 2003-02-08 2003-08-27 杭州华卫制药技术开发有限公司 注射用长春瑞滨粉针剂及制备方法
CN1552716A (zh) * 2003-06-03 2004-12-08 浙江海正药业股份有限公司 合成长春瑞滨的方法
CN1245409C (zh) * 2003-06-03 2006-03-15 浙江海正药业股份有限公司 长春瑞滨合成中间体脱水长春碱的制备方法
PL1830817T3 (pl) 2004-12-30 2013-06-28 Pf Medicament Stała trwała dyspersja pochodnej alkaloidu Vinca i sposób jej wytwarzania
FR2918567B1 (fr) * 2007-07-11 2012-08-03 Pf Medicament Composition pharmaceutique stable d'un sel hydrosoluble de vinorelbine.
CN101284842B (zh) * 2008-05-19 2010-06-09 华中科技大学 用硫酸长春碱合成长春瑞滨酒石酸盐的方法
CN102766149B (zh) * 2012-07-05 2014-09-24 深圳万乐药业有限公司 一种酒石酸长春瑞滨的制备方法
CN104725405A (zh) * 2013-12-20 2015-06-24 中国医药研究开发中心有限公司 长春瑞滨的制备方法

Also Published As

Publication number Publication date
US20190092792A1 (en) 2019-03-28
TW201734023A (zh) 2017-10-01
AR107829A1 (es) 2018-06-13
CA3014473A1 (en) 2017-09-14
RU2730521C2 (ru) 2020-08-24
EP3426665A1 (en) 2019-01-16
CN108779129A (zh) 2018-11-09
RU2018129465A3 (es) 2020-04-09
WO2017152972A1 (en) 2017-09-14
BR112018067637A2 (pt) 2019-01-02
RU2018129465A (ru) 2020-04-09
JP2019508436A (ja) 2019-03-28

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Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20230601