UY34594A - Derivados heterocíclicos bicíclicos, su preparación y su aplicación en terapéutica - Google Patents

Derivados heterocíclicos bicíclicos, su preparación y su aplicación en terapéutica

Info

Publication number
UY34594A
UY34594A UY0001034594A UY34594A UY34594A UY 34594 A UY34594 A UY 34594A UY 0001034594 A UY0001034594 A UY 0001034594A UY 34594 A UY34594 A UY 34594A UY 34594 A UY34594 A UY 34594A
Authority
UY
Uruguay
Prior art keywords
therapeutics
preparation
application
bicyclic heterocyclic
heterocyclic derivatives
Prior art date
Application number
UY0001034594A
Other languages
English (en)
Inventor
Alain Braun
Yann Foricher
Gilbert Marciniak
Nicolas Muzet
Eric Nicolai
Pascal Cecile
Bertrand Vivet
Fabrice Viviani
Olivier Crespin
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of UY34594A publication Critical patent/UY34594A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Psychiatry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

La invención se refiere a los derivados heterocíclicos bicíclicos, de fórmula general (I) a su procedimiento de preparación y aplicación en terapéutica.
UY0001034594A 2012-01-26 2013-01-25 Derivados heterocíclicos bicíclicos, su preparación y su aplicación en terapéutica UY34594A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR1250768A FR2986232B1 (fr) 2012-01-26 2012-01-26 Derives heterocycliques bicycliques, leur preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
UY34594A true UY34594A (es) 2013-09-02

Family

ID=47997597

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001034594A UY34594A (es) 2012-01-26 2013-01-25 Derivados heterocíclicos bicíclicos, su preparación y su aplicación en terapéutica

Country Status (26)

Country Link
US (1) US9120812B2 (es)
EP (1) EP2807172B1 (es)
JP (1) JP6068508B2 (es)
KR (1) KR20140125389A (es)
CN (1) CN104203958B (es)
AR (1) AR089782A1 (es)
AU (1) AU2013213261B2 (es)
BR (1) BR112014018226A8 (es)
CA (1) CA2862747A1 (es)
CY (1) CY1118852T1 (es)
DK (1) DK2807172T3 (es)
ES (1) ES2617880T3 (es)
FR (1) FR2986232B1 (es)
HR (1) HRP20170288T1 (es)
HU (1) HUE031917T2 (es)
IL (1) IL233774A (es)
LT (1) LT2807172T (es)
MX (1) MX348841B (es)
PL (1) PL2807172T3 (es)
PT (1) PT2807172T (es)
RU (1) RU2627269C2 (es)
SG (1) SG11201404325VA (es)
SI (1) SI2807172T1 (es)
TW (1) TWI572608B (es)
UY (1) UY34594A (es)
WO (1) WO2013111106A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ718487A (en) 2013-10-16 2020-01-31 Shanghai Yingli Pharm Co Ltd Fused heterocyclic compound, preparation method therefor, pharmaceutical composition, and uses thereof
CN107001317B (zh) * 2014-09-29 2019-05-24 山东轩竹医药科技有限公司 高选择性取代嘧啶类pi3k抑制剂
US10307707B2 (en) * 2017-05-17 2019-06-04 Thomas P. Daly 1-amino-2-methyl-2-propanol derivatives
CA3111980A1 (en) 2018-09-10 2020-03-19 Mirati Therapeutics, Inc. Combination therapies

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ533540A (en) * 2002-01-18 2006-04-28 Kyorin Seiyaku Kk Fused bicyclic pyrimidine derivatives that act as effective tachykinin receptor antagonists such as NK1 to treat tachykinin receptor-related pathological conditions
EP1562956A4 (en) * 2002-11-22 2007-10-10 Japan Tobacco Inc HETEROCYCLES CONTAINING FUSED BICYCLIC NITROGEN
EP2382207B1 (en) * 2008-11-11 2015-04-29 Xcovery Holding Company LLC Pi3k/mtor kinase inhibitors
AU2010254200A1 (en) * 2009-05-26 2011-12-08 Exelixis, Inc. Benzoxazepines as inhibitors of PI3K/m TOR and methods of their use and manufacture
AU2011256195A1 (en) * 2010-05-19 2012-12-06 Xcovery Holding Company, Llc. mTOR selective kinase inhibitors

Also Published As

Publication number Publication date
BR112014018226A8 (pt) 2017-07-11
WO2013111106A1 (en) 2013-08-01
CN104203958B (zh) 2017-05-31
MX348841B (es) 2017-06-30
EP2807172B1 (en) 2016-11-30
PT2807172T (pt) 2017-03-06
JP2015504914A (ja) 2015-02-16
RU2014134640A (ru) 2016-03-27
CN104203958A (zh) 2014-12-10
CY1118852T1 (el) 2018-01-10
RU2627269C2 (ru) 2017-08-04
SI2807172T1 (sl) 2017-03-31
LT2807172T (lt) 2017-03-27
FR2986232A1 (fr) 2013-08-02
HUE031917T2 (en) 2017-08-28
SG11201404325VA (en) 2014-08-28
DK2807172T3 (en) 2017-03-06
MX2014009084A (es) 2015-02-05
CA2862747A1 (en) 2013-08-01
KR20140125389A (ko) 2014-10-28
IL233774A (en) 2016-06-30
EP2807172A1 (en) 2014-12-03
TWI572608B (zh) 2017-03-01
US20140378433A1 (en) 2014-12-25
AU2013213261B2 (en) 2017-07-20
HRP20170288T1 (hr) 2017-04-21
TW201333016A (zh) 2013-08-16
US9120812B2 (en) 2015-09-01
AU2013213261A1 (en) 2014-08-21
ES2617880T3 (es) 2017-06-20
FR2986232B1 (fr) 2014-02-14
JP6068508B2 (ja) 2017-01-25
BR112014018226A2 (es) 2017-06-20
AR089782A1 (es) 2014-09-17
PL2807172T3 (pl) 2017-05-31

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Legal Events

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Effective date: 20210526