UY32561A - Derivados de n-[(7-aza-biciclo[2.2.1]hept-1-il)-aril-metil]-benzamida, su preparación y su aplicación en terapéutica. - Google Patents
Derivados de n-[(7-aza-biciclo[2.2.1]hept-1-il)-aril-metil]-benzamida, su preparación y su aplicación en terapéutica.Info
- Publication number
- UY32561A UY32561A UY0001032561A UY32561A UY32561A UY 32561 A UY32561 A UY 32561A UY 0001032561 A UY0001032561 A UY 0001032561A UY 32561 A UY32561 A UY 32561A UY 32561 A UY32561 A UY 32561A
- Authority
- UY
- Uruguay
- Prior art keywords
- alkyl
- groups
- alkoxy
- cycloalkyl
- halo
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/14—Nitrogen atoms not forming part of a nitro radical
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Addiction (AREA)
- Rheumatology (AREA)
- Psychology (AREA)
- Anesthesiology (AREA)
- Hospice & Palliative Care (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Compuestos de fórmula (I): en la que:- R representa un átomo de hidrógeno o un grupo elegido entre los grupos alquilo(C1-C6), cicloalquilo (C3-C7), opcionalmente sustituido con uno o varios grupos elegidos independientemente entre sí entre el átomo de flúor, los grupos cicloalquilo(C3-C7), alquenilo(C2-C4), fenilo, alcoxi(C1.C6), hidroxi; el grupo fenilo está opcionalmente sustituido con uno o varios grupos alcoxi(C1-C6);-R1 representa un grupo fenilo opcionalmente sustituido con uno o varios sustituyentes elegidos independientemente entre sí entre los átomos de halógeno, los grupos alquilo(C1-C6), alcoxi(C1-C6), halo-alquilo(C1-C6), hidroxi, halo.alcoxi(C1-C6)-SO2,-R2 representa uno o varios sustituyentes elegidos entre el átomo de hidrógeno, los átomos de halógeno, los grupos halo-alquilo(C1-C6), alquilo(C1-C6), cicloalquilo(C3-C7), cicloalqui(C3-C7)-alquilo(C1-C3), alcoxi(C1-C6), alquil(C1-C6)-tio, alquil(C1-C6)-SO2; en forma de base o de sal de adición a un ácido. Utilización en terapéutica y procedimiento de síntesis.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0901809A FR2944284A1 (fr) | 2009-04-14 | 2009-04-14 | Derives de n-°7-aza-bicyclo°2.2.1!hept-1-yl)-aryl-methyl! -benzamide, leur preparation et leur application en therapeutique |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UY32561A true UY32561A (es) | 2010-11-30 |
Family
ID=41228015
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UY0001032561A UY32561A (es) | 2009-04-14 | 2010-04-14 | Derivados de n-[(7-aza-biciclo[2.2.1]hept-1-il)-aril-metil]-benzamida, su preparación y su aplicación en terapéutica. |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP2419431A1 (es) |
| JP (1) | JP2012523448A (es) |
| KR (1) | KR20120013378A (es) |
| AR (1) | AR076276A1 (es) |
| AU (1) | AU2010238409A1 (es) |
| BR (1) | BRPI1015484A2 (es) |
| CA (1) | CA2758367A1 (es) |
| FR (1) | FR2944284A1 (es) |
| IL (1) | IL215673A0 (es) |
| MX (1) | MX2011010929A (es) |
| SG (1) | SG175222A1 (es) |
| TW (1) | TW201041581A (es) |
| UY (1) | UY32561A (es) |
| WO (1) | WO2010119222A1 (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20160045182A (ko) | 2014-10-16 | 2016-04-27 | 현대자동차주식회사 | 실린더 라이너용 회주철 및 이를 이용한 실린더 라이너의 제조방법 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2842804B1 (fr) * | 2002-07-29 | 2004-09-03 | Sanofi Synthelabo | Derives de n-[phenyl(piperidin-2-yl)methyl]benzamide, leur preparation et leur application en therapeutique |
| FR2861076B1 (fr) * | 2003-10-17 | 2006-01-06 | Sanofi Synthelabo | Derives de n-heterocyclymethylbenzamide, leur preparation et leur application en therapeutique |
| WO2008065500A2 (en) * | 2006-11-30 | 2008-06-05 | Pfizer Products Inc. | Heteroaryl amides as type i glycine transport inhibitors |
| TW200911808A (en) * | 2007-07-23 | 2009-03-16 | Astrazeneca Ab | Novel compounds |
-
2009
- 2009-04-14 FR FR0901809A patent/FR2944284A1/fr not_active Withdrawn
-
2010
- 2010-04-12 AR ARP100101220A patent/AR076276A1/es unknown
- 2010-04-13 WO PCT/FR2010/050711 patent/WO2010119222A1/fr active Application Filing
- 2010-04-13 KR KR1020117026894A patent/KR20120013378A/ko not_active Application Discontinuation
- 2010-04-13 BR BRPI1015484A patent/BRPI1015484A2/pt not_active Application Discontinuation
- 2010-04-13 EP EP10723665A patent/EP2419431A1/fr not_active Withdrawn
- 2010-04-13 TW TW099111503A patent/TW201041581A/zh unknown
- 2010-04-13 CA CA2758367A patent/CA2758367A1/fr not_active Abandoned
- 2010-04-13 JP JP2012505205A patent/JP2012523448A/ja not_active Withdrawn
- 2010-04-13 AU AU2010238409A patent/AU2010238409A1/en not_active Abandoned
- 2010-04-13 MX MX2011010929A patent/MX2011010929A/es not_active Application Discontinuation
- 2010-04-13 SG SG2011075017A patent/SG175222A1/en unknown
- 2010-04-14 UY UY0001032561A patent/UY32561A/es not_active Application Discontinuation
-
2011
- 2011-10-10 IL IL215673A patent/IL215673A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2010238409A1 (en) | 2011-11-03 |
| SG175222A1 (en) | 2011-11-28 |
| BRPI1015484A2 (pt) | 2016-04-26 |
| TW201041581A (en) | 2010-12-01 |
| IL215673A0 (en) | 2012-01-31 |
| WO2010119222A1 (fr) | 2010-10-21 |
| MX2011010929A (es) | 2011-11-02 |
| CA2758367A1 (fr) | 2010-10-21 |
| EP2419431A1 (fr) | 2012-02-22 |
| FR2944284A1 (fr) | 2010-10-15 |
| AR076276A1 (es) | 2011-06-01 |
| JP2012523448A (ja) | 2012-10-04 |
| KR20120013378A (ko) | 2012-02-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 109 | Application deemed to be withdrawn |
Effective date: 20150601 |