BRPI1015484A2 - derivados de n-[(7-aza-biciclo [2.2.1] hept-1-il)-aril-metil]-benzamida, o respectivo preparo e a respectiva aplicação em terapêutica - Google Patents
derivados de n-[(7-aza-biciclo [2.2.1] hept-1-il)-aril-metil]-benzamida, o respectivo preparo e a respectiva aplicação em terapêuticaInfo
- Publication number
- BRPI1015484A2 BRPI1015484A2 BRPI1015484A BRPI1015484A BRPI1015484A2 BR PI1015484 A2 BRPI1015484 A2 BR PI1015484A2 BR PI1015484 A BRPI1015484 A BR PI1015484A BR PI1015484 A BRPI1015484 A BR PI1015484A BR PI1015484 A2 BRPI1015484 A2 BR PI1015484A2
- Authority
- BR
- Brazil
- Prior art keywords
- alkyl
- alkoxy
- arylmethyl
- hept
- aza
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/14—Nitrogen atoms not forming part of a nitro radical
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Addiction (AREA)
- Rheumatology (AREA)
- Psychology (AREA)
- Anesthesiology (AREA)
- Hospice & Palliative Care (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
derivados de n-[(7-aza-biciclo [2.2.1] hept-1-il)-aril-metil]-benzamida, o respectivo preparo e a respectiva aplicação em terapêutica. na qual : -r representa um átomo de hidrogênio ou um grupo escolhido dentre os grupos (c~ 1~-c~ 6~) alquila, (c~ 3~-c~ 7~)-ciclo alquila, eventualmente substituído por um ou vários grupos escolhidos independentemente um do outro dentre o átomo de flúor, os grupos (c~ 3~-c~ 7~)-ciclo alquila, (c~ 2~-c~ 4~) alcenila, fenila, (c~ 1~-c~ 6~) alcóxi, hidróxi; o grupo fenila é eventualmente substituído por um ou vários grupos (c~ 1~-c~ 6~) alcóxi; -r~ 1~ representa um grupo fenila , eventualmente substituído por um ou vários substituintes escolhidos independentemente um do outro dentre os átomos de halogênio , os grupos (c~ 1~-c~ 6~) alquila, (c~ 1~- c~ 6~) alcóxi, halo-(c~ 1~c~ 6~) alquila, hidróxi, halo-(c~ 1~-c~ 6~) alcóxi, (c~ 1~-c~ 6~) alquila-tio, (c~ 1~-c~ 6~) alquila-so~ 2~;-r~ 2~ representa um ou vários substituintes escolhidos dentre o átomo de hidrogênio, os átomos de halogênio, os grupos halo-(c~ 1~-c~ 6~) alquila, (c~ 1~-c~ 6 ~) alquila, c~ 3~-c~ 7~)-ciclo alquila, (c~ 3~-c~ 7~) alquila, (c~ 1~-c~ 6~) alcóxi, (c~ 1~-c~ 6~) alquil-tio, (c~ 1~-c~ 6~) alquila-so~ 2~; no estado de base ou de sal de adição a um ácido. utilização em terapêutica e processo de síntese.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0901809A FR2944284A1 (fr) | 2009-04-14 | 2009-04-14 | Derives de n-°7-aza-bicyclo°2.2.1!hept-1-yl)-aryl-methyl! -benzamide, leur preparation et leur application en therapeutique |
PCT/FR2010/050711 WO2010119222A1 (fr) | 2009-04-14 | 2010-04-13 | Derives de n-[(7-aza-bicyclo[2.2.1]hept-1-yl)-aryl-methyl]-benzamide, leur preparation et leur application en therapeutique |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI1015484A2 true BRPI1015484A2 (pt) | 2016-04-26 |
Family
ID=41228015
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI1015484A BRPI1015484A2 (pt) | 2009-04-14 | 2010-04-13 | derivados de n-[(7-aza-biciclo [2.2.1] hept-1-il)-aril-metil]-benzamida, o respectivo preparo e a respectiva aplicação em terapêutica |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP2419431A1 (pt) |
JP (1) | JP2012523448A (pt) |
KR (1) | KR20120013378A (pt) |
AR (1) | AR076276A1 (pt) |
AU (1) | AU2010238409A1 (pt) |
BR (1) | BRPI1015484A2 (pt) |
CA (1) | CA2758367A1 (pt) |
FR (1) | FR2944284A1 (pt) |
IL (1) | IL215673A0 (pt) |
MX (1) | MX2011010929A (pt) |
SG (1) | SG175222A1 (pt) |
TW (1) | TW201041581A (pt) |
UY (1) | UY32561A (pt) |
WO (1) | WO2010119222A1 (pt) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20160045182A (ko) | 2014-10-16 | 2016-04-27 | 현대자동차주식회사 | 실린더 라이너용 회주철 및 이를 이용한 실린더 라이너의 제조방법 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2842804B1 (fr) * | 2002-07-29 | 2004-09-03 | Sanofi Synthelabo | Derives de n-[phenyl(piperidin-2-yl)methyl]benzamide, leur preparation et leur application en therapeutique |
FR2861076B1 (fr) * | 2003-10-17 | 2006-01-06 | Sanofi Synthelabo | Derives de n-heterocyclymethylbenzamide, leur preparation et leur application en therapeutique |
WO2008065500A2 (en) * | 2006-11-30 | 2008-06-05 | Pfizer Products Inc. | Heteroaryl amides as type i glycine transport inhibitors |
TW200911808A (en) * | 2007-07-23 | 2009-03-16 | Astrazeneca Ab | Novel compounds |
-
2009
- 2009-04-14 FR FR0901809A patent/FR2944284A1/fr not_active Withdrawn
-
2010
- 2010-04-12 AR ARP100101220A patent/AR076276A1/es unknown
- 2010-04-13 WO PCT/FR2010/050711 patent/WO2010119222A1/fr active Application Filing
- 2010-04-13 KR KR1020117026894A patent/KR20120013378A/ko not_active Application Discontinuation
- 2010-04-13 BR BRPI1015484A patent/BRPI1015484A2/pt not_active Application Discontinuation
- 2010-04-13 EP EP10723665A patent/EP2419431A1/fr not_active Withdrawn
- 2010-04-13 TW TW099111503A patent/TW201041581A/zh unknown
- 2010-04-13 CA CA2758367A patent/CA2758367A1/fr not_active Abandoned
- 2010-04-13 JP JP2012505205A patent/JP2012523448A/ja not_active Withdrawn
- 2010-04-13 AU AU2010238409A patent/AU2010238409A1/en not_active Abandoned
- 2010-04-13 MX MX2011010929A patent/MX2011010929A/es not_active Application Discontinuation
- 2010-04-13 SG SG2011075017A patent/SG175222A1/en unknown
- 2010-04-14 UY UY0001032561A patent/UY32561A/es not_active Application Discontinuation
-
2011
- 2011-10-10 IL IL215673A patent/IL215673A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
AU2010238409A1 (en) | 2011-11-03 |
SG175222A1 (en) | 2011-11-28 |
TW201041581A (en) | 2010-12-01 |
IL215673A0 (en) | 2012-01-31 |
WO2010119222A1 (fr) | 2010-10-21 |
MX2011010929A (es) | 2011-11-02 |
UY32561A (es) | 2010-11-30 |
CA2758367A1 (fr) | 2010-10-21 |
EP2419431A1 (fr) | 2012-02-22 |
FR2944284A1 (fr) | 2010-10-15 |
AR076276A1 (es) | 2011-06-01 |
JP2012523448A (ja) | 2012-10-04 |
KR20120013378A (ko) | 2012-02-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |