FR2944284A1 - Derives de n-°7-aza-bicyclo°2.2.1!hept-1-yl)-aryl-methyl! -benzamide, leur preparation et leur application en therapeutique - Google Patents
Derives de n-°7-aza-bicyclo°2.2.1!hept-1-yl)-aryl-methyl! -benzamide, leur preparation et leur application en therapeutique Download PDFInfo
- Publication number
- FR2944284A1 FR2944284A1 FR0901809A FR0901809A FR2944284A1 FR 2944284 A1 FR2944284 A1 FR 2944284A1 FR 0901809 A FR0901809 A FR 0901809A FR 0901809 A FR0901809 A FR 0901809A FR 2944284 A1 FR2944284 A1 FR 2944284A1
- Authority
- FR
- France
- Prior art keywords
- alkyl
- compound
- treatment
- disorders
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/14—Nitrogen atoms not forming part of a nitro radical
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Addiction (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Anesthesiology (AREA)
- Rheumatology (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Priority Applications (14)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0901809A FR2944284A1 (fr) | 2009-04-14 | 2009-04-14 | Derives de n-°7-aza-bicyclo°2.2.1!hept-1-yl)-aryl-methyl! -benzamide, leur preparation et leur application en therapeutique |
ARP100101220A AR076276A1 (es) | 2009-04-14 | 2010-04-12 | Derivados de n-[(7-aza-biciclo[2.2.1]hept-1-il)-aril-metil]-benzamida, su prepara-cion y su aplicacion en terapeutica |
SG2011075017A SG175222A1 (en) | 2009-04-14 | 2010-04-13 | Derivatives of n-[(7-aza-bicyclo[2.2.1]hept-1-yl)-aryl-methyl]-benzamide, preparation thereof, and therapeutic use thereof |
MX2011010929A MX2011010929A (es) | 2009-04-14 | 2010-04-13 | Derivados de n-[7-aza-biciclo[2.2.1]hept-1-il)-aril-metil]-benzami da, su preparacion y su uso en terapeutica. |
CA2758367A CA2758367A1 (fr) | 2009-04-14 | 2010-04-13 | Derives de n-[(7-aza-bicyclo[2.2.1]hept-1-yl)-aryl-methyl]-benzamide, leur preparation et leur application en therapeutique |
KR1020117026894A KR20120013378A (ko) | 2009-04-14 | 2010-04-13 | N-[(7-아자-비시클로[2.2.1]헵트-1-일)-아릴-메틸]-벤즈아미드의 유도체, 그의 제조법, 및 그의 치료 용도 |
JP2012505205A JP2012523448A (ja) | 2009-04-14 | 2010-04-13 | N−[(7−アザ−ビシクロ[2.2.1]ヘプト−1−イル)−アリール−メチル]−ベンズアミドの誘導体、これらの調製およびこれらの治療上の使用 |
AU2010238409A AU2010238409A1 (en) | 2009-04-14 | 2010-04-13 | Derivatives of N-[(7-aza-bicyclo[2.2.1]hept-1-yl)-aryl-methyl]-benzamide, preparation thereof, and therapeutic use thereof |
EP10723665A EP2419431A1 (fr) | 2009-04-14 | 2010-04-13 | Derives de n-[(7-aza-bicyclo[2.2.1]hept-1-yl)-aryl-methyl]-benzamide, leur preparation et leur application en therapeutique |
BRPI1015484A BRPI1015484A2 (pt) | 2009-04-14 | 2010-04-13 | derivados de n-[(7-aza-biciclo [2.2.1] hept-1-il)-aril-metil]-benzamida, o respectivo preparo e a respectiva aplicação em terapêutica |
TW099111503A TW201041581A (en) | 2009-04-14 | 2010-04-13 | N-[(7-azabicyclo[2.2.1]hept-1-yl)-aryl-methyl] benzamide derivatives, preparation thereof and therapeutic use thereof |
PCT/FR2010/050711 WO2010119222A1 (fr) | 2009-04-14 | 2010-04-13 | Derives de n-[(7-aza-bicyclo[2.2.1]hept-1-yl)-aryl-methyl]-benzamide, leur preparation et leur application en therapeutique |
UY0001032561A UY32561A (es) | 2009-04-14 | 2010-04-14 | Derivados de n-[(7-aza-biciclo[2.2.1]hept-1-il)-aril-metil]-benzamida, su preparación y su aplicación en terapéutica. |
IL215673A IL215673A0 (en) | 2009-04-14 | 2011-10-10 | Derivatives of n-[(7-aza-bicyclo[2.2.1]hept-1-yl)-aryl-methyl]-benzamide, preparation thereof, and therapeutic use thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0901809A FR2944284A1 (fr) | 2009-04-14 | 2009-04-14 | Derives de n-°7-aza-bicyclo°2.2.1!hept-1-yl)-aryl-methyl! -benzamide, leur preparation et leur application en therapeutique |
Publications (1)
Publication Number | Publication Date |
---|---|
FR2944284A1 true FR2944284A1 (fr) | 2010-10-15 |
Family
ID=41228015
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR0901809A Withdrawn FR2944284A1 (fr) | 2009-04-14 | 2009-04-14 | Derives de n-°7-aza-bicyclo°2.2.1!hept-1-yl)-aryl-methyl! -benzamide, leur preparation et leur application en therapeutique |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP2419431A1 (es) |
JP (1) | JP2012523448A (es) |
KR (1) | KR20120013378A (es) |
AR (1) | AR076276A1 (es) |
AU (1) | AU2010238409A1 (es) |
BR (1) | BRPI1015484A2 (es) |
CA (1) | CA2758367A1 (es) |
FR (1) | FR2944284A1 (es) |
IL (1) | IL215673A0 (es) |
MX (1) | MX2011010929A (es) |
SG (1) | SG175222A1 (es) |
TW (1) | TW201041581A (es) |
UY (1) | UY32561A (es) |
WO (1) | WO2010119222A1 (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20160045182A (ko) | 2014-10-16 | 2016-04-27 | 현대자동차주식회사 | 실린더 라이너용 회주철 및 이를 이용한 실린더 라이너의 제조방법 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2842804A1 (fr) * | 2002-07-29 | 2004-01-30 | Sanofi Synthelabo | Derives de n-[phenyl(piperidin-2-yl)methyl]benzamide, leur preparation et leur application en therapeutique |
FR2861076A1 (fr) * | 2003-10-17 | 2005-04-22 | Sanofi Synthelabo | Derives de n-heterocyclymethylbenzamide, leur preparation et leur application en therapeutique |
WO2008065500A2 (en) * | 2006-11-30 | 2008-06-05 | Pfizer Products Inc. | Heteroaryl amides as type i glycine transport inhibitors |
WO2009013535A1 (en) * | 2007-07-23 | 2009-01-29 | Astrazeneca Ab | 2-azabicyclo(2.2.2)octane derivatives as modulators of the glycine transporter i receptor |
-
2009
- 2009-04-14 FR FR0901809A patent/FR2944284A1/fr not_active Withdrawn
-
2010
- 2010-04-12 AR ARP100101220A patent/AR076276A1/es unknown
- 2010-04-13 JP JP2012505205A patent/JP2012523448A/ja not_active Withdrawn
- 2010-04-13 AU AU2010238409A patent/AU2010238409A1/en not_active Abandoned
- 2010-04-13 CA CA2758367A patent/CA2758367A1/fr not_active Abandoned
- 2010-04-13 BR BRPI1015484A patent/BRPI1015484A2/pt not_active Application Discontinuation
- 2010-04-13 EP EP10723665A patent/EP2419431A1/fr not_active Withdrawn
- 2010-04-13 TW TW099111503A patent/TW201041581A/zh unknown
- 2010-04-13 WO PCT/FR2010/050711 patent/WO2010119222A1/fr active Application Filing
- 2010-04-13 SG SG2011075017A patent/SG175222A1/en unknown
- 2010-04-13 KR KR1020117026894A patent/KR20120013378A/ko not_active Application Discontinuation
- 2010-04-13 MX MX2011010929A patent/MX2011010929A/es not_active Application Discontinuation
- 2010-04-14 UY UY0001032561A patent/UY32561A/es not_active Application Discontinuation
-
2011
- 2011-10-10 IL IL215673A patent/IL215673A0/en unknown
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2842804A1 (fr) * | 2002-07-29 | 2004-01-30 | Sanofi Synthelabo | Derives de n-[phenyl(piperidin-2-yl)methyl]benzamide, leur preparation et leur application en therapeutique |
FR2861076A1 (fr) * | 2003-10-17 | 2005-04-22 | Sanofi Synthelabo | Derives de n-heterocyclymethylbenzamide, leur preparation et leur application en therapeutique |
WO2008065500A2 (en) * | 2006-11-30 | 2008-06-05 | Pfizer Products Inc. | Heteroaryl amides as type i glycine transport inhibitors |
WO2009013535A1 (en) * | 2007-07-23 | 2009-01-29 | Astrazeneca Ab | 2-azabicyclo(2.2.2)octane derivatives as modulators of the glycine transporter i receptor |
Also Published As
Publication number | Publication date |
---|---|
WO2010119222A1 (fr) | 2010-10-21 |
CA2758367A1 (fr) | 2010-10-21 |
UY32561A (es) | 2010-11-30 |
KR20120013378A (ko) | 2012-02-14 |
EP2419431A1 (fr) | 2012-02-22 |
AU2010238409A1 (en) | 2011-11-03 |
SG175222A1 (en) | 2011-11-28 |
JP2012523448A (ja) | 2012-10-04 |
MX2011010929A (es) | 2011-11-02 |
AR076276A1 (es) | 2011-06-01 |
TW201041581A (en) | 2010-12-01 |
BRPI1015484A2 (pt) | 2016-04-26 |
IL215673A0 (en) | 2012-01-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |
Effective date: 20121228 |