UY32051A - Compuestos de azetidinas polisustituidos, su preparación y su aplicación en terapéutica - Google Patents
Compuestos de azetidinas polisustituidos, su preparación y su aplicación en terapéuticaInfo
- Publication number
- UY32051A UY32051A UY0001032051A UY32051A UY32051A UY 32051 A UY32051 A UY 32051A UY 0001032051 A UY0001032051 A UY 0001032051A UY 32051 A UY32051 A UY 32051A UY 32051 A UY32051 A UY 32051A
- Authority
- UY
- Uruguay
- Prior art keywords
- preparation
- polyustituted
- therapeutics
- application
- compounds
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
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- A—HUMAN NECESSITIES
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Physical Education & Sports Medicine (AREA)
- Obesity (AREA)
- Psychiatry (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Urology & Nephrology (AREA)
- Addiction (AREA)
- Endocrinology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Ophthalmology & Optometry (AREA)
- Psychology (AREA)
- Transplantation (AREA)
- Virology (AREA)
Abstract
Compuestos de azetidinas polisustituidos que responden a la fórmula (I) en el estado de base o de sal de adición a un ácido, donde los radicales, sustituyentes e índices son tales como se especifican en la Memoria descriptiva y en las Reivindicaciones. Se divulgan los procedimientos de preparación y su aplicación terapéutica en el tratamiento o la prevención de enfermedades que implican a los receptores de los cannabinoides CB1.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0804595A FR2934995B1 (fr) | 2008-08-14 | 2008-08-14 | Composes d'azetidines polysubstitues, leur preparation et leur application en therapeutique |
Publications (1)
Publication Number | Publication Date |
---|---|
UY32051A true UY32051A (es) | 2010-03-26 |
Family
ID=40352689
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UY0001032051A UY32051A (es) | 2008-08-14 | 2009-08-14 | Compuestos de azetidinas polisustituidos, su preparación y su aplicación en terapéutica |
Country Status (16)
Country | Link |
---|---|
US (1) | US20110152236A1 (es) |
EP (1) | EP2313393A1 (es) |
JP (1) | JP2011530575A (es) |
KR (1) | KR20110044782A (es) |
CN (1) | CN102186839A (es) |
AR (1) | AR073043A1 (es) |
AU (1) | AU2009281057A1 (es) |
BR (1) | BRPI0917464A2 (es) |
CA (1) | CA2733397A1 (es) |
FR (1) | FR2934995B1 (es) |
IL (1) | IL211210A0 (es) |
MX (1) | MX2011001678A (es) |
RU (1) | RU2011109180A (es) |
TW (1) | TW201011019A (es) |
UY (1) | UY32051A (es) |
WO (1) | WO2010018328A1 (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20130102477A1 (en) | 2010-06-23 | 2013-04-25 | Ryan D. Morin | Biomarkers for non-hodgkin lymphomas and uses thereof |
DK2614369T3 (en) | 2010-09-10 | 2016-05-02 | Epizyme Inc | METHOD FOR DETERMINING THE SUITABILITY OF HUMAN EZH2 INHIBITORS TREATED |
US9175331B2 (en) | 2010-09-10 | 2015-11-03 | Epizyme, Inc. | Inhibitors of human EZH2, and methods of use thereof |
TW201733984A (zh) | 2011-04-13 | 2017-10-01 | 雅酶股份有限公司 | 經取代之苯化合物 |
JO3438B1 (ar) | 2011-04-13 | 2019-10-20 | Epizyme Inc | مركبات بنزين مستبدلة بأريل أو أريل غير متجانس |
ES2745016T3 (es) | 2012-04-13 | 2020-02-27 | Epizyme Inc | Bromhidrato de N-((4,6-dimetil-2-oxo-L,2-dihidropiridin-3-il)metil)-5-(etil(tetrahidro-2H-piran-4-il)amino)-4-metil-4'-(morfolinometil)-[L,1'-bifenil]-3-carboxamida para su uso en el tratamiento de un trastorno proliferativo celular del sistema hematológico |
EP2906538A4 (en) | 2012-10-15 | 2016-05-11 | Epizyme Inc | SUBSTITUTED BENZOL COMPOUNDS |
JP6608812B2 (ja) | 2013-10-16 | 2019-11-20 | エピザイム,インコーポレイティド | Ezh2阻害のための塩酸塩形 |
JP2023509452A (ja) | 2020-01-03 | 2023-03-08 | バーグ エルエルシー | がんを処置するためのube2kモジュレータとしての多環式アミド |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2805817B1 (fr) * | 2000-03-03 | 2002-04-26 | Aventis Pharma Sa | Compositions pharmaceutiques contenant des derives d'azetidine, les nouveaux derives d'azetidine et leur preparation |
FR2928149B1 (fr) * | 2008-02-29 | 2011-01-14 | Sanofi Aventis | Composes derives d'azetidines, leur preparation et leur application en therapeutique |
FR2934996B1 (fr) * | 2008-08-14 | 2010-08-27 | Sanofi Aventis | Composes polysubstitues d'azetidines, leur preparation et leur application en therapeutique |
-
2008
- 2008-08-14 FR FR0804595A patent/FR2934995B1/fr not_active Expired - Fee Related
-
2009
- 2009-08-13 TW TW098127313A patent/TW201011019A/zh unknown
- 2009-08-13 WO PCT/FR2009/001003 patent/WO2010018328A1/fr active Application Filing
- 2009-08-13 US US13/058,913 patent/US20110152236A1/en not_active Abandoned
- 2009-08-13 EP EP09737012A patent/EP2313393A1/fr not_active Withdrawn
- 2009-08-13 AU AU2009281057A patent/AU2009281057A1/en not_active Abandoned
- 2009-08-13 MX MX2011001678A patent/MX2011001678A/es not_active Application Discontinuation
- 2009-08-13 CN CN2009801408208A patent/CN102186839A/zh active Pending
- 2009-08-13 RU RU2011109180/04A patent/RU2011109180A/ru not_active Application Discontinuation
- 2009-08-13 CA CA2733397A patent/CA2733397A1/fr not_active Abandoned
- 2009-08-13 AR ARP090103131A patent/AR073043A1/es unknown
- 2009-08-13 JP JP2011522538A patent/JP2011530575A/ja not_active Withdrawn
- 2009-08-13 BR BRPI0917464A patent/BRPI0917464A2/pt not_active Application Discontinuation
- 2009-08-13 KR KR1020117005735A patent/KR20110044782A/ko not_active Application Discontinuation
- 2009-08-14 UY UY0001032051A patent/UY32051A/es not_active Application Discontinuation
-
2011
- 2011-02-13 IL IL211210A patent/IL211210A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
AU2009281057A1 (en) | 2010-02-18 |
CA2733397A1 (fr) | 2010-02-18 |
WO2010018328A1 (fr) | 2010-02-18 |
EP2313393A1 (fr) | 2011-04-27 |
US20110152236A1 (en) | 2011-06-23 |
IL211210A0 (en) | 2011-04-28 |
BRPI0917464A2 (pt) | 2015-12-01 |
KR20110044782A (ko) | 2011-04-29 |
FR2934995B1 (fr) | 2010-08-27 |
AR073043A1 (es) | 2010-10-06 |
CN102186839A (zh) | 2011-09-14 |
MX2011001678A (es) | 2011-04-05 |
JP2011530575A (ja) | 2011-12-22 |
FR2934995A1 (fr) | 2010-02-19 |
TW201011019A (en) | 2010-03-16 |
RU2011109180A (ru) | 2012-09-20 |
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