FR2934996B1 - Composes polysubstitues d'azetidines, leur preparation et leur application en therapeutique - Google Patents

Composes polysubstitues d'azetidines, leur preparation et leur application en therapeutique

Info

Publication number
FR2934996B1
FR2934996B1 FR0804596A FR0804596A FR2934996B1 FR 2934996 B1 FR2934996 B1 FR 2934996B1 FR 0804596 A FR0804596 A FR 0804596A FR 0804596 A FR0804596 A FR 0804596A FR 2934996 B1 FR2934996 B1 FR 2934996B1
Authority
FR
France
Prior art keywords
azetidine
preparation
therapeutic use
polysubstituted compounds
polysubstituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0804596A
Other languages
English (en)
Other versions
FR2934996A1 (fr
Inventor
Florian Auger
Patrick Bernardelli
Jean Francois Sabuco
Corinne Terrier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Sanofi Aventis France
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0804596A priority Critical patent/FR2934996B1/fr
Application filed by Sanofi Aventis France filed Critical Sanofi Aventis France
Priority to MX2011001669A priority patent/MX2011001669A/es
Priority to KR1020117005732A priority patent/KR20110042114A/ko
Priority to PCT/FR2009/001004 priority patent/WO2010018329A1/fr
Priority to CA2734082A priority patent/CA2734082A1/fr
Priority to EP09736249A priority patent/EP2313392A1/fr
Priority to CN2009801408180A priority patent/CN102186838A/zh
Priority to AU2009281058A priority patent/AU2009281058A1/en
Priority to JP2011522539A priority patent/JP2011530576A/ja
Priority to ARP090103132A priority patent/AR073044A1/es
Priority to RU2011109204/04A priority patent/RU2011109204A/ru
Priority to US13/058,885 priority patent/US20110183961A1/en
Priority to BRPI0917944A priority patent/BRPI0917944A2/pt
Priority to TW098127314A priority patent/TW201022248A/zh
Priority to UY0001032050A priority patent/UY32050A/es
Publication of FR2934996A1 publication Critical patent/FR2934996A1/fr
Application granted granted Critical
Publication of FR2934996B1 publication Critical patent/FR2934996B1/fr
Priority to IL211209A priority patent/IL211209A0/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
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    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
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    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
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    • A—HUMAN NECESSITIES
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    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Psychiatry (AREA)
  • Obesity (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Addiction (AREA)
  • Oncology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Reproductive Health (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Otolaryngology (AREA)
  • Urology & Nephrology (AREA)
  • Psychology (AREA)
FR0804596A 2008-08-14 2008-08-14 Composes polysubstitues d'azetidines, leur preparation et leur application en therapeutique Expired - Fee Related FR2934996B1 (fr)

Priority Applications (16)

Application Number Priority Date Filing Date Title
FR0804596A FR2934996B1 (fr) 2008-08-14 2008-08-14 Composes polysubstitues d'azetidines, leur preparation et leur application en therapeutique
RU2011109204/04A RU2011109204A (ru) 2008-08-14 2009-08-13 Пилизамещенные соединения азетидинов, их получение и их применение в терапии
PCT/FR2009/001004 WO2010018329A1 (fr) 2008-08-14 2009-08-13 Composes polysubstitues d'azetidines, leur preparation et leur application en therapeutique
CA2734082A CA2734082A1 (fr) 2008-08-14 2009-08-13 Composes polysubstitues d'azetidines, leur preparation et leur application en therapeutique
EP09736249A EP2313392A1 (fr) 2008-08-14 2009-08-13 Composes polysubstitues d'azetidines, leur preparation et leur application en therapeutique
CN2009801408180A CN102186838A (zh) 2008-08-14 2009-08-13 氮杂环丁烷多取代的化合物、其制备及其治疗用途
AU2009281058A AU2009281058A1 (en) 2008-08-14 2009-08-13 Azetidine polysubstituted compounds, preparation thereof, and therapeutic application thereof
JP2011522539A JP2011530576A (ja) 2008-08-14 2009-08-13 アゼチジン多置換化合物、これらの調製、およびこれらの治療的適用
MX2011001669A MX2011001669A (es) 2008-08-14 2009-08-13 Compuestos polisustituidos de azetidinas, su preparacion y su aplicacion en terapeutica.
KR1020117005732A KR20110042114A (ko) 2008-08-14 2009-08-13 아제티딘 다치환된 화합물, 그의 제조법 및 그의 치료 용도
US13/058,885 US20110183961A1 (en) 2008-08-14 2009-08-13 Azetidine polysubstituted compounds, preparation thereof, and therapeutic application thereof
BRPI0917944A BRPI0917944A2 (pt) 2008-08-14 2009-08-13 compostos polissubstituídos de azetidinas, preparação dos mesmo e aplicação terapêuticas dos mesmos.
TW098127314A TW201022248A (en) 2008-08-14 2009-08-13 Polysubstituted azetidine compounds, preparation thereof and therapeutic use thereof
ARP090103132A AR073044A1 (es) 2008-08-14 2009-08-13 Compuestos polisustituidos de azetidinas, su preparacion y su aplicacion en terapeutica
UY0001032050A UY32050A (es) 2008-08-14 2009-08-14 Compuestos polisustituidos de azetidinas, su preparación y su aplicación en terapéutica
IL211209A IL211209A0 (en) 2008-08-14 2011-02-13 Azetidine polysubstituted compounds, preparation thereof, and therapeutic application thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0804596A FR2934996B1 (fr) 2008-08-14 2008-08-14 Composes polysubstitues d'azetidines, leur preparation et leur application en therapeutique

Publications (2)

Publication Number Publication Date
FR2934996A1 FR2934996A1 (fr) 2010-02-19
FR2934996B1 true FR2934996B1 (fr) 2010-08-27

Family

ID=40352477

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0804596A Expired - Fee Related FR2934996B1 (fr) 2008-08-14 2008-08-14 Composes polysubstitues d'azetidines, leur preparation et leur application en therapeutique

Country Status (16)

Country Link
US (1) US20110183961A1 (fr)
EP (1) EP2313392A1 (fr)
JP (1) JP2011530576A (fr)
KR (1) KR20110042114A (fr)
CN (1) CN102186838A (fr)
AR (1) AR073044A1 (fr)
AU (1) AU2009281058A1 (fr)
BR (1) BRPI0917944A2 (fr)
CA (1) CA2734082A1 (fr)
FR (1) FR2934996B1 (fr)
IL (1) IL211209A0 (fr)
MX (1) MX2011001669A (fr)
RU (1) RU2011109204A (fr)
TW (1) TW201022248A (fr)
UY (1) UY32050A (fr)
WO (1) WO2010018329A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2934995B1 (fr) * 2008-08-14 2010-08-27 Sanofi Aventis Composes d'azetidines polysubstitues, leur preparation et leur application en therapeutique
CN103524393B (zh) * 2013-10-29 2015-01-07 广东省中医院 氮杂环丁烷-3-磺胺类衍生物及其合成方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2805817B1 (fr) * 2000-03-03 2002-04-26 Aventis Pharma Sa Compositions pharmaceutiques contenant des derives d'azetidine, les nouveaux derives d'azetidine et leur preparation

Also Published As

Publication number Publication date
WO2010018329A1 (fr) 2010-02-18
BRPI0917944A2 (pt) 2015-11-17
TW201022248A (en) 2010-06-16
KR20110042114A (ko) 2011-04-22
MX2011001669A (es) 2011-03-24
CN102186838A (zh) 2011-09-14
RU2011109204A (ru) 2012-09-20
AU2009281058A1 (en) 2010-02-18
IL211209A0 (en) 2011-04-28
JP2011530576A (ja) 2011-12-22
FR2934996A1 (fr) 2010-02-19
EP2313392A1 (fr) 2011-04-27
CA2734082A1 (fr) 2010-02-18
AR073044A1 (es) 2010-10-06
UY32050A (es) 2010-03-26
US20110183961A1 (en) 2011-07-28

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