UY29879A1 - Derivados de 6-heteroarilpiridoindolona, su preparación y su aplicación en terapéutica - Google Patents

Derivados de 6-heteroarilpiridoindolona, su preparación y su aplicación en terapéutica

Info

Publication number
UY29879A1
UY29879A1 UY29879A UY29879A UY29879A1 UY 29879 A1 UY29879 A1 UY 29879A1 UY 29879 A UY29879 A UY 29879A UY 29879 A UY29879 A UY 29879A UY 29879 A1 UY29879 A1 UY 29879A1
Authority
UY
Uruguay
Prior art keywords
therapeutics
preparation
application
heteroarilpiridoindolona
derivatives
Prior art date
Application number
UY29879A
Other languages
English (en)
Inventor
Jegham Samir
Ciapetti Paola
Wermuth Camille Georges
Muneaux Yvette
Derocq Jean Marie
Casellas Pierre
Bourrie Bernard
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of UY29879A1 publication Critical patent/UY29879A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pyridine Compounds (AREA)

Abstract

Se divulgan compuestos derivados de 6-heteroarilpiridoindolona, que responden a la fórmula (I): donde los sustituyentes, radicales y parámetros son como se describieron en la Memoria Descriptiva y Reivindicaciones. Proceso de preparación y aplicación en terapéutica.
UY29879A 2005-10-20 2006-10-20 Derivados de 6-heteroarilpiridoindolona, su preparación y su aplicación en terapéutica UY29879A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0510730A FR2892416B1 (fr) 2005-10-20 2005-10-20 Derives de 6-heteroarylpyridoindolone, leur preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
UY29879A1 true UY29879A1 (es) 2007-05-31

Family

ID=35953891

Family Applications (1)

Application Number Title Priority Date Filing Date
UY29879A UY29879A1 (es) 2005-10-20 2006-10-20 Derivados de 6-heteroarilpiridoindolona, su preparación y su aplicación en terapéutica

Country Status (33)

Country Link
US (1) US8063061B2 (es)
EP (1) EP1940840B1 (es)
JP (1) JP2009512666A (es)
KR (1) KR20080057300A (es)
CN (1) CN101312970A (es)
AR (1) AR056874A1 (es)
AT (1) ATE474840T1 (es)
AU (1) AU2006303210A1 (es)
BR (1) BRPI0617684A2 (es)
CA (1) CA2625502C (es)
CR (1) CR9873A (es)
CY (1) CY1110891T1 (es)
DE (1) DE602006015675D1 (es)
DK (1) DK1940840T3 (es)
DO (1) DOP2006000225A (es)
EA (1) EA014873B1 (es)
EC (1) ECSP088370A (es)
ES (1) ES2348745T3 (es)
FR (1) FR2892416B1 (es)
GT (1) GT200600462A (es)
HR (1) HRP20100572T1 (es)
IL (1) IL190519A0 (es)
MA (1) MA29961B1 (es)
NO (1) NO20082226L (es)
PE (1) PE20070591A1 (es)
PL (1) PL1940840T3 (es)
PT (1) PT1940840E (es)
SI (1) SI1940840T1 (es)
TN (1) TNSN08161A1 (es)
TW (1) TW200734336A (es)
UY (1) UY29879A1 (es)
WO (1) WO2007045758A1 (es)
ZA (1) ZA200803445B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2823975B1 (fr) 2001-04-27 2003-05-30 Sanofi Synthelabo Nouvelle utilisation de pyridoindolone
US7456193B2 (en) 2002-10-23 2008-11-25 Sanofi-Aventis Pyridoindolone derivatives substituted in the 3-position by a heterocyclic group, their preparation and their application in therapeutics
FR2846329B1 (fr) 2002-10-23 2004-12-03 Sanofi Synthelabo Derives de pyridoindolone substitues en -3 par un phenyle, leur preparation et leur application en therapeutique
FR2869316B1 (fr) 2004-04-21 2006-06-02 Sanofi Synthelabo Derives de pyridoindolone substitues en -6, leur preparation et leur application en therapeutique.
BR112014028585B1 (pt) 2012-05-17 2020-12-22 Genentech , Inc processo para fabricação de aminoácidos, e seus intermediários
WO2015086642A1 (en) 2013-12-13 2015-06-18 F. Hoffmann-La Roche Ag Inhibitors of bruton's tyrosine kinase
CA2929785C (en) 2013-12-13 2018-02-13 F. Hoffmann-La Roche Ag Inhibitors of bruton's tyrosine kinase

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1268772A (en) 1968-03-15 1972-03-29 Glaxo Lab Ltd NOVEL alpha-CARBOLINE DERIVATIVES, THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME
US4263304A (en) 1978-06-05 1981-04-21 Sumitomo Chemical Company, Limited 7 H-indolo[2,3-c]isoquinolines
SU833971A1 (ru) 1979-07-10 1981-05-30 Ленинградский Химико-Фармацевтическийинститут Способ получени 3-фенил-2-оксо- - КАРбОлиНОВ
FR2595701B1 (fr) 1986-03-17 1988-07-01 Sanofi Sa Derives du pyrido-indole, leur application a titre de medicaments et les compositions les renfermant
WO1995028493A1 (en) 1994-04-13 1995-10-26 The Rockefeller University Aav-mediated delivery of dna to cells of the nervous system
DE19502753A1 (de) 1995-01-23 1996-07-25 Schering Ag Neue 9H-Pyrido[3,4-b]indol-Derivate
FR2765582B1 (fr) 1997-07-03 1999-08-06 Synthelabo Derives de 3-alkyl-1,9-dihydro-2h-pyrido[2,3-b]indol-2-one leur preparation et leur application en therapeutique
FR2765581B1 (fr) 1997-07-03 1999-08-06 Synthelabo Derives de 3-aryl-1,9-dihydro-2h-pyrido[2,3-b]indol-2-one, leur preparation et leur application en therapeutique
EP1068205A1 (en) 1998-04-02 2001-01-17 Neurogen Corporation Aminoalkyl substituted 5,6,7,8-tetrahydro-9h pyrimidino 2,3-b]indole and 5,6,7,8-tetrahydro-9h-pyrimidino 4,5-b]indole derivatives: crf1 specific ligands
IT1313592B1 (it) 1999-08-03 2002-09-09 Novuspharma Spa Derivati di 1h-pirido 3,4-b indol-1-one.
US20020156016A1 (en) 2001-03-30 2002-10-24 Gerald Minuk Control of cell growth by altering cell membrane potentials
FR2823975B1 (fr) 2001-04-27 2003-05-30 Sanofi Synthelabo Nouvelle utilisation de pyridoindolone
FR2846329B1 (fr) 2002-10-23 2004-12-03 Sanofi Synthelabo Derives de pyridoindolone substitues en -3 par un phenyle, leur preparation et leur application en therapeutique
FR2846330B1 (fr) * 2002-10-23 2004-12-03 Sanofi Synthelabo Derives de pyridoindolone substitues en -3 par groupe heterocyclique, leur preparation et leur application en therapeutique
US7456193B2 (en) 2002-10-23 2008-11-25 Sanofi-Aventis Pyridoindolone derivatives substituted in the 3-position by a heterocyclic group, their preparation and their application in therapeutics
FR2869316B1 (fr) * 2004-04-21 2006-06-02 Sanofi Synthelabo Derives de pyridoindolone substitues en -6, leur preparation et leur application en therapeutique.

Also Published As

Publication number Publication date
EA200801123A1 (ru) 2009-02-27
AU2006303210A1 (en) 2007-04-26
CA2625502C (fr) 2012-01-10
BRPI0617684A2 (pt) 2011-11-01
PT1940840E (pt) 2010-10-13
TW200734336A (en) 2007-09-16
US20080262020A1 (en) 2008-10-23
SI1940840T1 (sl) 2010-11-30
US8063061B2 (en) 2011-11-22
DE602006015675D1 (de) 2010-09-02
PL1940840T3 (pl) 2010-12-31
IL190519A0 (en) 2008-11-03
ES2348745T3 (es) 2010-12-13
CN101312970A (zh) 2008-11-26
DOP2006000225A (es) 2007-08-31
EP1940840A1 (fr) 2008-07-09
EA014873B1 (ru) 2011-02-28
CY1110891T1 (el) 2015-06-10
CA2625502A1 (fr) 2007-04-26
ZA200803445B (en) 2010-02-24
DK1940840T3 (da) 2010-11-22
MA29961B1 (fr) 2008-11-03
GT200600462A (es) 2007-07-17
CR9873A (es) 2008-05-05
HRP20100572T1 (hr) 2011-01-31
FR2892416A1 (fr) 2007-04-27
KR20080057300A (ko) 2008-06-24
FR2892416B1 (fr) 2008-06-27
TNSN08161A1 (en) 2009-10-30
ECSP088370A (es) 2008-05-30
EP1940840B1 (fr) 2010-07-21
JP2009512666A (ja) 2009-03-26
PE20070591A1 (es) 2007-08-03
ATE474840T1 (de) 2010-08-15
NO20082226L (no) 2008-07-01
AR056874A1 (es) 2007-10-31
WO2007045758A1 (fr) 2007-04-26

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Legal Events

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Effective date: 20120515