DE602006015675D1 - 6-heteroarylpyridoindolon-derivate, ihre herstellung und ihre therapeutische anwendung - Google Patents
6-heteroarylpyridoindolon-derivate, ihre herstellung und ihre therapeutische anwendungInfo
- Publication number
- DE602006015675D1 DE602006015675D1 DE602006015675T DE602006015675T DE602006015675D1 DE 602006015675 D1 DE602006015675 D1 DE 602006015675D1 DE 602006015675 T DE602006015675 T DE 602006015675T DE 602006015675 T DE602006015675 T DE 602006015675T DE 602006015675 D1 DE602006015675 D1 DE 602006015675D1
- Authority
- DE
- Germany
- Prior art keywords
- heteroarylpyridoindolon
- derivatives
- preparation
- therapeutic application
- therapeutic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0510730A FR2892416B1 (fr) | 2005-10-20 | 2005-10-20 | Derives de 6-heteroarylpyridoindolone, leur preparation et leur application en therapeutique |
| PCT/FR2006/002330 WO2007045758A1 (fr) | 2005-10-20 | 2006-10-17 | Derives de 6-heteroarylpyridoindolone, leur preparation et leur application en therapeutique |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE602006015675D1 true DE602006015675D1 (de) | 2010-09-02 |
Family
ID=35953891
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602006015675T Active DE602006015675D1 (de) | 2005-10-20 | 2006-10-17 | 6-heteroarylpyridoindolon-derivate, ihre herstellung und ihre therapeutische anwendung |
Country Status (33)
| Country | Link |
|---|---|
| US (1) | US8063061B2 (de) |
| EP (1) | EP1940840B1 (de) |
| JP (1) | JP2009512666A (de) |
| KR (1) | KR20080057300A (de) |
| CN (1) | CN101312970A (de) |
| AR (1) | AR056874A1 (de) |
| AT (1) | ATE474840T1 (de) |
| AU (1) | AU2006303210A1 (de) |
| BR (1) | BRPI0617684A2 (de) |
| CA (1) | CA2625502C (de) |
| CR (1) | CR9873A (de) |
| CY (1) | CY1110891T1 (de) |
| DE (1) | DE602006015675D1 (de) |
| DK (1) | DK1940840T3 (de) |
| DO (1) | DOP2006000225A (de) |
| EA (1) | EA014873B1 (de) |
| EC (1) | ECSP088370A (de) |
| ES (1) | ES2348745T3 (de) |
| FR (1) | FR2892416B1 (de) |
| GT (1) | GT200600462A (de) |
| HR (1) | HRP20100572T1 (de) |
| IL (1) | IL190519A0 (de) |
| MA (1) | MA29961B1 (de) |
| NO (1) | NO20082226L (de) |
| PE (1) | PE20070591A1 (de) |
| PL (1) | PL1940840T3 (de) |
| PT (1) | PT1940840E (de) |
| SI (1) | SI1940840T1 (de) |
| TN (1) | TNSN08161A1 (de) |
| TW (1) | TW200734336A (de) |
| UY (1) | UY29879A1 (de) |
| WO (1) | WO2007045758A1 (de) |
| ZA (1) | ZA200803445B (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2823975B1 (fr) | 2001-04-27 | 2003-05-30 | Sanofi Synthelabo | Nouvelle utilisation de pyridoindolone |
| FR2846329B1 (fr) | 2002-10-23 | 2004-12-03 | Sanofi Synthelabo | Derives de pyridoindolone substitues en -3 par un phenyle, leur preparation et leur application en therapeutique |
| US7456193B2 (en) | 2002-10-23 | 2008-11-25 | Sanofi-Aventis | Pyridoindolone derivatives substituted in the 3-position by a heterocyclic group, their preparation and their application in therapeutics |
| FR2869316B1 (fr) | 2004-04-21 | 2006-06-02 | Sanofi Synthelabo | Derives de pyridoindolone substitues en -6, leur preparation et leur application en therapeutique. |
| MX350443B (es) * | 2012-05-17 | 2017-09-06 | Genentech Inc | Proceso para hacer compuestos de aminoácidos. |
| EP3080099B1 (de) | 2013-12-13 | 2018-04-11 | F.Hoffmann-La Roche Ag | Hemmer der bruton-tyrosinkinase |
| US9802920B2 (en) | 2013-12-13 | 2017-10-31 | Hoffman-La Roche Inc. | Inhibitors of bruton's tyrosine kinase |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1268772A (en) | 1968-03-15 | 1972-03-29 | Glaxo Lab Ltd | NOVEL alpha-CARBOLINE DERIVATIVES, THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME |
| US4263304A (en) | 1978-06-05 | 1981-04-21 | Sumitomo Chemical Company, Limited | 7 H-indolo[2,3-c]isoquinolines |
| SU833971A1 (ru) | 1979-07-10 | 1981-05-30 | Ленинградский Химико-Фармацевтическийинститут | Способ получени 3-фенил-2-оксо- - КАРбОлиНОВ |
| FR2595701B1 (fr) | 1986-03-17 | 1988-07-01 | Sanofi Sa | Derives du pyrido-indole, leur application a titre de medicaments et les compositions les renfermant |
| CA2187626C (en) | 1994-04-13 | 2009-11-03 | Michael G. Kaplitt | Aav-mediated delivery of dna to cells of the nervous system |
| DE19502753A1 (de) | 1995-01-23 | 1996-07-25 | Schering Ag | Neue 9H-Pyrido[3,4-b]indol-Derivate |
| FR2765581B1 (fr) | 1997-07-03 | 1999-08-06 | Synthelabo | Derives de 3-aryl-1,9-dihydro-2h-pyrido[2,3-b]indol-2-one, leur preparation et leur application en therapeutique |
| FR2765582B1 (fr) | 1997-07-03 | 1999-08-06 | Synthelabo | Derives de 3-alkyl-1,9-dihydro-2h-pyrido[2,3-b]indol-2-one leur preparation et leur application en therapeutique |
| AU3375999A (en) | 1998-04-02 | 1999-10-25 | Neurogen Corporation | Aminoalkyl substituted 5,6,7,8-tetrahydro-9h pyrimidino(2,3-b)indole and 5,6,7,8-tetrahydro-9h-pyrimidino(4,5-b)indole derivatives: crf1 specific ligands |
| IT1313592B1 (it) | 1999-08-03 | 2002-09-09 | Novuspharma Spa | Derivati di 1h-pirido 3,4-b indol-1-one. |
| US20020156016A1 (en) | 2001-03-30 | 2002-10-24 | Gerald Minuk | Control of cell growth by altering cell membrane potentials |
| FR2823975B1 (fr) | 2001-04-27 | 2003-05-30 | Sanofi Synthelabo | Nouvelle utilisation de pyridoindolone |
| US7456193B2 (en) | 2002-10-23 | 2008-11-25 | Sanofi-Aventis | Pyridoindolone derivatives substituted in the 3-position by a heterocyclic group, their preparation and their application in therapeutics |
| FR2846330B1 (fr) * | 2002-10-23 | 2004-12-03 | Sanofi Synthelabo | Derives de pyridoindolone substitues en -3 par groupe heterocyclique, leur preparation et leur application en therapeutique |
| FR2846329B1 (fr) | 2002-10-23 | 2004-12-03 | Sanofi Synthelabo | Derives de pyridoindolone substitues en -3 par un phenyle, leur preparation et leur application en therapeutique |
| FR2869316B1 (fr) | 2004-04-21 | 2006-06-02 | Sanofi Synthelabo | Derives de pyridoindolone substitues en -6, leur preparation et leur application en therapeutique. |
-
2005
- 2005-10-20 FR FR0510730A patent/FR2892416B1/fr not_active Expired - Fee Related
-
2006
- 2006-10-05 PE PE2006001217A patent/PE20070591A1/es not_active Application Discontinuation
- 2006-10-16 DO DO2006000225A patent/DOP2006000225A/es unknown
- 2006-10-17 DE DE602006015675T patent/DE602006015675D1/de active Active
- 2006-10-17 EP EP06830970A patent/EP1940840B1/de active Active
- 2006-10-17 AT AT06830970T patent/ATE474840T1/de active
- 2006-10-17 EA EA200801123A patent/EA014873B1/ru not_active IP Right Cessation
- 2006-10-17 ZA ZA200803445A patent/ZA200803445B/xx unknown
- 2006-10-17 PL PL06830970T patent/PL1940840T3/pl unknown
- 2006-10-17 GT GT200600462A patent/GT200600462A/es unknown
- 2006-10-17 CN CNA2006800433247A patent/CN101312970A/zh active Pending
- 2006-10-17 SI SI200630800T patent/SI1940840T1/sl unknown
- 2006-10-17 KR KR1020087009373A patent/KR20080057300A/ko not_active Application Discontinuation
- 2006-10-17 ES ES06830970T patent/ES2348745T3/es active Active
- 2006-10-17 AU AU2006303210A patent/AU2006303210A1/en not_active Abandoned
- 2006-10-17 DK DK06830970.7T patent/DK1940840T3/da active
- 2006-10-17 WO PCT/FR2006/002330 patent/WO2007045758A1/fr active Application Filing
- 2006-10-17 JP JP2008536081A patent/JP2009512666A/ja not_active Withdrawn
- 2006-10-17 CA CA2625502A patent/CA2625502C/fr not_active Expired - Fee Related
- 2006-10-17 BR BRPI0617684-4A patent/BRPI0617684A2/pt not_active IP Right Cessation
- 2006-10-17 PT PT06830970T patent/PT1940840E/pt unknown
- 2006-10-18 AR ARP060104538A patent/AR056874A1/es unknown
- 2006-10-19 TW TW095138582A patent/TW200734336A/zh unknown
- 2006-10-20 UY UY29879A patent/UY29879A1/es unknown
-
2008
- 2008-03-30 IL IL190519A patent/IL190519A0/en unknown
- 2008-04-08 CR CR9873A patent/CR9873A/es not_active Application Discontinuation
- 2008-04-09 US US12/100,079 patent/US8063061B2/en not_active Expired - Fee Related
- 2008-04-10 TN TNP2008000161A patent/TNSN08161A1/en unknown
- 2008-04-15 EC EC2008008370A patent/ECSP088370A/es unknown
- 2008-05-14 NO NO20082226A patent/NO20082226L/no not_active Application Discontinuation
- 2008-05-19 MA MA30945A patent/MA29961B1/fr unknown
-
2010
- 2010-10-13 CY CY20101100910T patent/CY1110891T1/el unknown
- 2010-10-19 HR HR20100572T patent/HRP20100572T1/hr unknown
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