UY26268A1 - Procedimiento para preparar acidos a traves de alfa-cloroep xi- esteres ley 17164 art 127 - Google Patents

Procedimiento para preparar acidos a traves de alfa-cloroep xi- esteres ley 17164 art 127

Info

Publication number
UY26268A1
UY26268A1 UY26268A UY26268A UY26268A1 UY 26268 A1 UY26268 A1 UY 26268A1 UY 26268 A UY26268 A UY 26268A UY 26268 A UY26268 A UY 26268A UY 26268 A1 UY26268 A1 UY 26268A1
Authority
UY
Uruguay
Prior art keywords
chloroep
law
alpha
esters
procedure
Prior art date
Application number
UY26268A
Other languages
English (en)
Inventor
Ann M Diederich Y Vance Novak
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of UY26268A1 publication Critical patent/UY26268A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

Esta invención se refiere a un método para preparar ciertos ácidos de la fórmula (I): a través de un cloroepoxi-éster, que son útiles como inhibidores de la fosfodiesterasa 4.
UY26268A 1999-08-06 2000-08-02 Procedimiento para preparar acidos a traves de alfa-cloroep xi- esteres ley 17164 art 127 UY26268A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14757699P 1999-08-06 1999-08-06

Publications (1)

Publication Number Publication Date
UY26268A1 true UY26268A1 (es) 2001-01-31

Family

ID=22522121

Family Applications (1)

Application Number Title Priority Date Filing Date
UY26268A UY26268A1 (es) 1999-08-06 2000-08-02 Procedimiento para preparar acidos a traves de alfa-cloroep xi- esteres ley 17164 art 127

Country Status (26)

Country Link
EP (1) EP1200394B1 (es)
JP (1) JP2003506431A (es)
KR (1) KR20020022793A (es)
CN (4) CN1530362A (es)
AR (1) AR025028A1 (es)
AT (1) ATE340780T1 (es)
AU (1) AU774582B2 (es)
BR (1) BR0013025A (es)
CA (1) CA2381010A1 (es)
CO (1) CO5190744A1 (es)
CZ (1) CZ2002428A3 (es)
DE (1) DE60030981T2 (es)
EC (1) ECSP003599A (es)
ES (1) ES2272310T3 (es)
HK (1) HK1047080A1 (es)
HU (1) HUP0202453A2 (es)
IL (1) IL147365A0 (es)
MX (1) MXPA02001337A (es)
NO (1) NO20020561L (es)
NZ (1) NZ516945A (es)
PE (1) PE20010398A1 (es)
PL (1) PL353347A1 (es)
TR (1) TR200200307T2 (es)
UY (1) UY26268A1 (es)
WO (1) WO2001010822A1 (es)
ZA (1) ZA200200965B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101116828B (zh) * 2006-08-03 2011-06-01 中国科学院大连化学物理研究所 手性吡啶双噁唑啉催化剂及制备方法和应用
WO2016172496A1 (en) 2015-04-23 2016-10-27 Constellation Pharmaceuticals, Inc. Lsd1 inhibitors and uses thereof
HRP20231369T1 (hr) 2016-10-26 2024-02-16 Constellation Pharmaceuticals, Inc. Inhibitori lsd1 i njihova medicinska upotreba

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3803593A (en) * 1992-04-02 1993-11-08 Smithkline Beecham Corporation Compounds
NZ251092A (en) * 1992-04-02 1996-12-20 Smithkline Beecham Corp 4-cyano-cyclohexane derivatives; medicaments; used in treating asthma
JP3195352B2 (ja) * 1992-04-02 2001-08-06 スミスクライン・ビーチャム・コーポレイション アレルギーおよび炎症疾患の治療用化合物
AU3924993A (en) * 1992-04-02 1993-11-08 Smithkline Beecham Corporation Compounds useful for treating inflammatory diseases and inhibiting production of tumor necrosis factor
GB9404706D0 (en) * 1994-03-11 1994-04-27 Smithkline Beecham Corp Compounds
AR012550A1 (es) * 1997-02-12 2000-11-08 Smithkline Beecham Corp Metodo para preparar acidos 4-fenil-4-ciano-ciclohexanoicos sustituidos y compuestos intermediarios

Also Published As

Publication number Publication date
HK1047080A1 (zh) 2003-02-07
ES2272310T3 (es) 2007-05-01
NO20020561D0 (no) 2002-02-05
PL353347A1 (en) 2003-11-17
CN1597675A (zh) 2005-03-23
AU774582B2 (en) 2004-07-01
CN1530362A (zh) 2004-09-22
DE60030981D1 (de) 2006-11-09
JP2003506431A (ja) 2003-02-18
IL147365A0 (en) 2002-08-14
PE20010398A1 (es) 2001-06-14
AU6622200A (en) 2001-03-05
WO2001010822A1 (en) 2001-02-15
ECSP003599A (es) 2002-03-25
ZA200200965B (en) 2003-04-30
EP1200394A4 (en) 2004-12-01
CA2381010A1 (en) 2001-02-15
AR025028A1 (es) 2002-11-06
CN1368955A (zh) 2002-09-11
TR200200307T2 (tr) 2002-05-21
CN1217923C (zh) 2005-09-07
NO20020561L (no) 2002-02-05
HUP0202453A2 (en) 2002-10-28
CN1530360A (zh) 2004-09-22
CN1266119C (zh) 2006-07-26
BR0013025A (pt) 2002-04-16
DE60030981T2 (de) 2007-09-06
EP1200394A1 (en) 2002-05-02
CO5190744A1 (es) 2002-08-29
ATE340780T1 (de) 2006-10-15
KR20020022793A (ko) 2002-03-27
EP1200394B1 (en) 2006-09-27
MXPA02001337A (es) 2002-07-22
CZ2002428A3 (cs) 2002-06-12
NZ516945A (en) 2004-01-30

Similar Documents

Publication Publication Date Title
ES2134051T3 (es) Procedimiento para la preparacion de sildenafil.
BR9804214A (pt) Compostos.
GT200000190A (es) Procedimiento para la obtencion de 1,2,3,4-tetrahidroquinolinas-4-carboxiamino-2-sustituidas.
EA200000358A1 (ru) Способ получения диарилпиридинов, полезных в качестве ингибиторов cox-2
UY27606A1 (es) Inhibidores de la fosfarasa
GT199900011A (es) Nuevos derivados del acido dihidroxihexanoico
AR006058A1 (es) Procedimientos para preparar compuestos de dicianoacetato y de 1,2-pirazol-5-amino-3-substituido
UY26133A1 (es) Derivado sustituido de pirazol.
EA200100129A1 (ru) Способ получения гидроксиметилтиобутановой кислоты
MX9305093A (es) Nuevos derivadosindano-2 mercaptoacetilamina triciclicos 2-sustituidos, utiles como inhibidores de la encefalinasa.
EA200100040A1 (ru) Химический синтез морфолиновых производных
ATE365036T1 (de) Creatinester-pronutrient-verbindungen und formulierungen
EA200200101A1 (ru) Получение замещенных пиперидин-4-онов
EA199900948A1 (ru) Способ получения 2-арил-3-арил-5-галогенпиридинов, используемых в качестве ингибиторов cox-2
UY26268A1 (es) Procedimiento para preparar acidos a traves de alfa-cloroep xi- esteres ley 17164 art 127
TR200200494T2 (tr) Yağlı asit sintazı inhibitörleri.
EA199900741A1 (ru) Способ получения эпросартана
ES2185196T3 (es) Un procedimiento para la preparacion de tetraazamacrociclos.
NO20053208D0 (no) Metode for reduktiv dehalogenering.
EA199900740A1 (ru) Способ получения эпросартана (варианты)
PT1054869E (pt) Derivados de 3,4-di-hidroquinolina como inibidores de sintases dommonoxido de azoto (nos)
DE69703115T2 (de) Zwischenprodukte um 2-imidazolin-5onederivate herzustellen.
ES2190602T3 (es) Procedimiento para la obtencion de los acidos 3-ciano-2,4-dihalogeno-5-fluor-benzoicos.
FR2809002B1 (fr) Utilisation de derives de l'acide n,n'-dibenzyl ethylene diamine n,n'-diacetique comme agent anti-pollution
IL157402A0 (en) Method for producing d-pantothenic acid and/or salts therefor as an additive for animal feed

Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20100830