UY25821A1 - Preparaciones de una combinación farmacéutica de carvedilol e hidroclorotiazida - Google Patents

Preparaciones de una combinación farmacéutica de carvedilol e hidroclorotiazida

Info

Publication number
UY25821A1
UY25821A1 UY25821A UY25821A UY25821A1 UY 25821 A1 UY25821 A1 UY 25821A1 UY 25821 A UY25821 A UY 25821A UY 25821 A UY25821 A UY 25821A UY 25821 A1 UY25821 A1 UY 25821A1
Authority
UY
Uruguay
Prior art keywords
carvedilol
pharmaceutical combination
hydrochlorotiazide
preparations
hydrochlorothiazide
Prior art date
Application number
UY25821A
Other languages
English (en)
Inventor
Rudolf Heller
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8233041&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UY25821(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of UY25821A1 publication Critical patent/UY25821A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

La presente invención se refiere a una preparación de una combinación farmacéutica para el tratamiento de trastornos cardíacos y cardiovasculares tales como hipertensión, angina de pecho, insuficiencia cardíaca y enfermedades relacionadas, que contiene las substancias activas carvedilol o una sal farmacéuticamente aceptable del mismo e hidroclorotiazida o una sal farmacéuticamente aceptable de la misma, así como aditivos usuales farmacéuticamente. El proceso de producción para la preparación de la combninación, puede comprender los pasos de producción del granulado de carvedilol, de hidroclorotiazida, tratamiento de ambos granulados hasta obtener una masa prensada con una humedad de 6 a20% y una densidad de granel entre 0.1 y 1.5 g/ml
UY25821A 1998-11-27 1999-11-26 Preparaciones de una combinación farmacéutica de carvedilol e hidroclorotiazida UY25821A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98122489 1998-11-27

Publications (1)

Publication Number Publication Date
UY25821A1 true UY25821A1 (es) 2001-07-31

Family

ID=8233041

Family Applications (1)

Application Number Title Priority Date Filing Date
UY25821A UY25821A1 (es) 1998-11-27 1999-11-26 Preparaciones de una combinación farmacéutica de carvedilol e hidroclorotiazida

Country Status (22)

Country Link
US (3) US6403579B1 (es)
EP (1) EP1131072B1 (es)
JP (2) JP2002531395A (es)
KR (1) KR100421347B1 (es)
CN (1) CN1184971C (es)
AR (1) AR020287A1 (es)
AT (1) ATE238056T1 (es)
AU (1) AU765977B2 (es)
BR (1) BR9915610A (es)
CA (1) CA2352361C (es)
CO (1) CO5011053A1 (es)
DE (1) DE69907252T2 (es)
DK (1) DK1131072T3 (es)
ES (1) ES2195638T3 (es)
MY (1) MY121831A (es)
PE (1) PE20001302A1 (es)
PT (1) PT1131072E (es)
TR (3) TR200200981T2 (es)
TW (1) TWI228414B (es)
UY (1) UY25821A1 (es)
WO (1) WO2000032174A2 (es)
ZA (1) ZA200104280B (es)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20001302A1 (es) * 1998-11-27 2000-11-30 Hoffmann La Roche Preparaciones de una combinacion farmaceutica que contiene carvedilol e hidroclorotiazida
AU2001297631A1 (en) * 2000-10-24 2002-09-04 Smithkline Beecham Corporation Novel formulations of carvedilol
US20030070584A1 (en) 2001-05-15 2003-04-17 Cynthia Gulian Dip coating compositions containing cellulose ethers
IN191028B (es) * 2001-05-17 2003-09-13 Sun Pharmaceutical Ind Ltd
US8309118B2 (en) 2001-09-28 2012-11-13 Mcneil-Ppc, Inc. Film forming compositions containing sucralose
US8101209B2 (en) 2001-10-09 2012-01-24 Flamel Technologies Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
WO2003092622A2 (en) * 2002-04-30 2003-11-13 Sb Pharmco Puerto Rico Inc. Carvedilol monocitrate monohydrate
EP1539140A4 (en) 2002-06-27 2005-12-07 Sb Pharmco Inc CARVEDILOLHYDOBROMID
KR20140006111A (ko) 2002-06-27 2014-01-15 스미스클라인 비이참 (코르크) 리미티드 카베딜롤 인산염 및(또는) 그의 용매화물, 상응하는 조성물, 및(또는) 치료 방법
EP1562552A1 (en) 2002-11-08 2005-08-17 Egalet A/S Controlled release carvedilol compositions
WO2004084868A1 (en) 2003-03-26 2004-10-07 Egalet A/S Morphine controlled release system
EP1615888A1 (en) * 2003-04-21 2006-01-18 Matrix Laboratories Ltd Process for the preparation of carvedilol form-ii
AU2003272851A1 (en) * 2003-09-26 2005-04-14 Shuyi Zhang Sustained release preparation containing hydrochlorothiazide
US20050175695A1 (en) * 2003-11-25 2005-08-11 Catherine Castan Carvedilol free base, salts, anhydrous forms or solvates thereof, corresponding pharmaceutical compositions, controlled release formulations, and treatment or delivery methods
JP2007512372A (ja) 2003-11-25 2007-05-17 エスビー・ファルムコ・プエルト・リコ・インコーポレイテッド カルベジロール塩、対応する組成物、送達および/または治療方法
EP1686967A4 (en) * 2003-11-25 2012-08-08 Smithkline Beecham Cork Ltd CARVEDILOL-FREE BASE, SALTS, WATER-FREE FORMS OR SOLVATES THEREOF, CORRESPONDING PHARMACEUTICAL COMPOSITIONS, CONTROLLED RELEASE FORMULAS AND TREATMENT OR DISPOSAL PROCEDURES
DE602004005748T2 (de) * 2003-12-02 2007-12-27 Nicox S.A., Sophia Antipolis Nitrooxy-derivate von carvedilol und anderen betablockern als antihypertensiva
NZ560232A (en) * 2005-02-25 2010-11-26 Hoffmann La Roche Tablets with improved drug substance dispersibility
ATE499090T1 (de) * 2006-06-16 2011-03-15 Lek Pharmaceuticals Pharmazeutische zusammensetzung mit hydrochlorothiazid und telmisartan
GB0612540D0 (en) * 2006-06-23 2006-08-02 Novartis Ag Galenical formulations of organic compounds
WO2008114276A1 (en) * 2007-03-16 2008-09-25 Lupin Limited Novel oral controlled release composition of carvedilol
WO2008148798A2 (en) 2007-06-04 2008-12-11 Egalet A/S Controlled release pharmaceutical compositions for prolonged effect
AU2010211220B2 (en) 2009-02-06 2013-08-01 Egalet Ltd. Immediate release composition resistant to abuse by intake of alcohol
NZ597283A (en) 2009-06-24 2013-07-26 Egalet Ltd Controlled release formulations
CA2792647A1 (en) * 2010-03-10 2011-09-15 Nogra Pharma Limited Compositions for colon lavage and methods of making and using same

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2815926A1 (de) 1978-04-13 1979-10-18 Boehringer Mannheim Gmbh Neue carbazolyl-(4)-oxy-propanolamin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
FR2643556B1 (fr) * 1989-02-27 1993-03-05 Sanofi Sa Composition pharmaceutique a liberation prolongee d'acide valproique
CZ286723B6 (cs) * 1991-01-30 2000-06-14 The Wellcome Foundation Limited Tablety dispergovatelné ve vodě
ES2106818T3 (es) * 1991-10-30 1997-11-16 Glaxo Group Ltd Composicion multicapa que contiene antagonistas de histamina o secotina.
TW483763B (en) * 1994-09-02 2002-04-21 Astra Ab Pharmaceutical composition comprising of ramipril and dihydropyridine compound
US5760069A (en) * 1995-02-08 1998-06-02 Boehringer Mannheim Pharmaceuticals Corporation-Smithkline Beecham Corporation Limited Partnership #1 Method of treatment for decreasing mortality resulting from congestive heart failure
FR2752162B1 (fr) * 1996-08-07 1998-11-06 Jouveinal Lab Comprime de maleate de trimebutine pellicule
DE19637082A1 (de) * 1996-09-12 1998-03-19 Boehringer Mannheim Gmbh Schnellzerfallende Pellets
PE20001302A1 (es) * 1998-11-27 2000-11-30 Hoffmann La Roche Preparaciones de una combinacion farmaceutica que contiene carvedilol e hidroclorotiazida

Also Published As

Publication number Publication date
JP2007077160A (ja) 2007-03-29
ES2195638T3 (es) 2003-12-01
WO2000032174A2 (en) 2000-06-08
MY121831A (en) 2006-02-28
WO2000032174A3 (en) 2000-11-16
AU1506500A (en) 2000-06-19
TR200101470T2 (tr) 2001-11-21
PT1131072E (pt) 2003-08-29
KR20010080578A (ko) 2001-08-22
TR200200982T2 (tr) 2002-06-21
DK1131072T3 (da) 2003-08-11
CA2352361C (en) 2007-01-02
ATE238056T1 (de) 2003-05-15
AU765977B2 (en) 2003-10-09
DE69907252T2 (de) 2004-01-29
ZA200104280B (en) 2002-08-26
JP2002531395A (ja) 2002-09-24
CN1328460A (zh) 2001-12-26
AR020287A1 (es) 2002-05-02
BR9915610A (pt) 2001-08-14
EP1131072B1 (en) 2003-04-23
PE20001302A1 (es) 2000-11-30
CN1184971C (zh) 2005-01-19
TR200200981T2 (tr) 2002-06-21
DE69907252D1 (de) 2003-05-28
CO5011053A1 (es) 2001-02-28
TWI228414B (en) 2005-03-01
US20020052367A1 (en) 2002-05-02
CA2352361A1 (en) 2000-06-08
KR100421347B1 (ko) 2004-03-06
EP1131072A2 (en) 2001-09-12
US20040087578A1 (en) 2004-05-06
US6403579B1 (en) 2002-06-11

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Legal Events

Date Code Title Description
ABAN Application deemed to be withdrawn (no publication fee paid)

Effective date: 20081201