UY25374A1 - Composiciones de apomorfina útiles en el tratamiento de disfunción sexual femenina - Google Patents
Composiciones de apomorfina útiles en el tratamiento de disfunción sexual femeninaInfo
- Publication number
- UY25374A1 UY25374A1 UY25374A UY25374A UY25374A1 UY 25374 A1 UY25374 A1 UY 25374A1 UY 25374 A UY25374 A UY 25374A UY 25374 A UY25374 A UY 25374A UY 25374 A1 UY25374 A1 UY 25374A1
- Authority
- UY
- Uruguay
- Prior art keywords
- amount
- sexual dysfunction
- female sexual
- treatment
- ampomorphine
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Gynecology & Obstetrics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Compounds Of Unknown Constitution (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Abstract
Forma de dosificación sublingual para el mejoramiento de la disfunción sexual femenina, que comprende apomorfina o una sal de adición de ácido farmacéuticamente aceptable de la misma, contenida en una cantidad de 2 miligramos a 12 miligramos de ampomorfina, de modo que la cantidad útil sea suficiente para incrementar el flujo de sangre intraclitorial y el flujo sanguíneo de las paredes vaginales que se produce por estimulación de de dicha mujer, pero menos que la cantidad que provoca náuseas; la dosis puede también comprender una beta-ciclodextrina (más particularmente hidroxipropil-beta-ciclodextrina). La forma de dosificación también puede incluir manitol y ácido ascórbico. Se incluye en especial una dosificación que comprende ampomorfina o sal de adición de la misma en una cantidad suficiente para mantener la concentración del plasma entre 1 a 2 nanogramos por milímetro de plasma durante la actividad sexual.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/016,252 US5945117A (en) | 1998-01-30 | 1998-01-30 | Treatment of female sexual dysfunction |
Publications (1)
Publication Number | Publication Date |
---|---|
UY25374A1 true UY25374A1 (es) | 1999-09-27 |
Family
ID=21776169
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UY25374A UY25374A1 (es) | 1998-01-30 | 1999-01-29 | Composiciones de apomorfina útiles en el tratamiento de disfunción sexual femenina |
Country Status (34)
Country | Link |
---|---|
US (2) | US5945117A (es) |
EP (1) | EP1056419A4 (es) |
JP (1) | JP2002501875A (es) |
KR (1) | KR20010040477A (es) |
CN (1) | CN1250221C (es) |
AR (1) | AR017976A1 (es) |
AU (1) | AU752928B2 (es) |
BG (1) | BG64667B1 (es) |
BR (1) | BR9908038A (es) |
CA (1) | CA2322289A1 (es) |
CO (1) | CO4970819A1 (es) |
CR (1) | CR5959A (es) |
DZ (1) | DZ2714A1 (es) |
GC (1) | GC0000096A (es) |
GT (1) | GT199900013A (es) |
HK (1) | HK1040901B (es) |
HN (1) | HN1999000015A (es) |
HU (1) | HUP0101268A3 (es) |
IL (2) | IL137569A0 (es) |
JO (1) | JO2085B1 (es) |
MA (1) | MA26600A1 (es) |
MX (1) | MXPA00007447A (es) |
NO (1) | NO319821B1 (es) |
NZ (1) | NZ506597A (es) |
PA (1) | PA8467801A1 (es) |
PE (1) | PE20000240A1 (es) |
PL (1) | PL194350B1 (es) |
SK (1) | SK11362000A3 (es) |
TN (1) | TNSN99008A1 (es) |
TR (1) | TR200002220T2 (es) |
TW (1) | TW550069B (es) |
UY (1) | UY25374A1 (es) |
WO (1) | WO1999038467A1 (es) |
ZA (1) | ZA99686B (es) |
Families Citing this family (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6395744B1 (en) * | 1994-04-22 | 2002-05-28 | Queen's University At Kingston | Method and compositions for the treatment or amelioration of female sexual dysfunction |
US20020165122A1 (en) * | 1994-04-22 | 2002-11-07 | Heaton Jeremy P. W. | Method and compositions for the treatment or amelioration of female sexual dysfunction |
US20050065161A1 (en) * | 1996-02-02 | 2005-03-24 | Nitromed, Inc. | Nitrosated and nitrosylated alpha-adrenergic receptor antagonist compounds, compositions and their uses |
US6472425B1 (en) | 1997-10-31 | 2002-10-29 | Nitromed, Inc. | Methods for treating female sexual dysfunctions |
US5945117A (en) * | 1998-01-30 | 1999-08-31 | Pentech Pharmaceuticals, Inc. | Treatment of female sexual dysfunction |
AU2003204720B2 (en) * | 1998-05-29 | 2006-06-29 | Tap Pharmaceutical Products Inc. | Methods for the normalization of sexual response and amelioration of long term genital tissue degradation |
JP2002518435A (ja) * | 1998-06-22 | 2002-06-25 | クイーンズ ユニバーシティ アット キングストン | 女性の性機能不全の治療または改善のための方法および組成物 |
US20050245494A1 (en) * | 1999-07-01 | 2005-11-03 | 40 J's Llc | Methods to treat one or all of the defined etiologies of female sexual dysfunction |
US20040254153A1 (en) * | 1999-11-08 | 2004-12-16 | Pfizer Inc | Compounds for the treatment of female sexual dysfunction |
BR0005797A (pt) * | 2000-03-20 | 2001-10-16 | Abbott Lab | Métodos para o tratamento de disfunção sexual com apomorfina em nìveis de concentração plasmática especificados |
WO2001076602A1 (en) * | 2000-04-07 | 2001-10-18 | Tap Pharmaceutical Products Inc. | Apomorphine derivatives and methods for their use |
US6762202B2 (en) | 2000-05-09 | 2004-07-13 | Nitromed, Inc. | Infrared thermography and methods of use |
US6737084B2 (en) | 2000-06-27 | 2004-05-18 | Qualilife | Compositions and methods for enhancing or treating female sexual response |
US7223406B2 (en) * | 2000-07-21 | 2007-05-29 | The Regents Of The University Of California | Methods and compositions for preventing and treating male erectile dysfunction and female sexual arousal disorder |
AU2001278981A1 (en) * | 2000-07-21 | 2002-02-05 | Tom F Lue | Prevention and treatment of sexual arousal disorders |
US20020065286A1 (en) * | 2000-08-21 | 2002-05-30 | Davies Michael John | Treatment of wounds |
AU2002235129A1 (en) | 2000-11-15 | 2002-05-27 | Tap Pharmaceutical Products Inc. | Treatment of anti-depression drug-induced sexual dysfunction with apomorphine |
CZ20031458A3 (cs) * | 2000-11-22 | 2004-02-18 | Abbott Laboratories | Léčivo pro léčení sexuální dysfunkce savce |
JP2004520389A (ja) * | 2001-02-08 | 2004-07-08 | ファルマシア・コーポレーション | 性的不全の治療のための早期効果発現薬剤 |
CN1720054A (zh) * | 2002-03-19 | 2006-01-11 | 布雷恩及比扬德生物科技公司 | 阿朴吗啡和其类似物的糖苷和原酸酯糖苷衍生物及其用途 |
US20030219696A1 (en) * | 2002-05-23 | 2003-11-27 | Moreland Gerald W. | Method and apparatus for preventing backflow in dental saliva evacuators |
GB0219961D0 (en) | 2002-08-28 | 2002-10-02 | Pfizer Ltd | Oxytocin inhibitors |
GB0221711D0 (en) * | 2002-09-19 | 2002-10-30 | Ardana Bioscience Ltd | Methods |
CA2445212A1 (en) * | 2002-10-10 | 2004-04-10 | Queen's University At Kingston | Treatment of sexual dysfunction |
CA2451267A1 (en) * | 2002-12-13 | 2004-06-13 | Warner-Lambert Company Llc | Pharmaceutical uses for alpha2delta ligands |
US20040204439A1 (en) * | 2003-04-14 | 2004-10-14 | Staniforth John Nicholas | Composition, device, and method for treating sexual dysfunction via inhalation |
BRPI0409380A (pt) * | 2003-04-14 | 2006-04-18 | Vectura Ltd | composições farmacêuticas |
US7306812B2 (en) | 2003-05-09 | 2007-12-11 | Cephalon, Inc. | Dissolvable backing layer for use with a transmucosal delivery device |
US7276246B2 (en) * | 2003-05-09 | 2007-10-02 | Cephalon, Inc. | Dissolvable backing layer for use with a transmucosal delivery device |
GB0314054D0 (en) * | 2003-06-17 | 2003-07-23 | Pfizer Ltd | Amide derivatives as selective serotonin re-uptake inhibitors |
US20050054688A1 (en) * | 2003-08-08 | 2005-03-10 | Pfizer Inc | Selective serotonin reuptake inhibitors in the treatment of disease |
DE10338174A1 (de) * | 2003-08-20 | 2005-03-24 | Lts Lohmann Therapie-Systeme Ag | Transdermale Arzneimittelzubereitungen mit Wirkstoffkombinationen zur Behandlung der Parkinson-Krankheit |
US7291640B2 (en) * | 2003-09-22 | 2007-11-06 | Pfizer Inc. | Substituted triazole derivatives as oxytocin antagonists |
GB0409744D0 (en) * | 2004-04-30 | 2004-06-09 | Pfizer Ltd | Novel compounds |
BRPI0510453A (pt) * | 2004-04-30 | 2007-10-30 | Warner Lambert Co | composto substituìdos com morfolina para o tratamento de distúrbios do sistema nervoso central |
DE602006003416D1 (de) * | 2005-03-21 | 2008-12-11 | Pfizer Ltd | Substituierte triazolderivate als oxytocinantagonisten |
JP2008533193A (ja) * | 2005-03-21 | 2008-08-21 | ファイザー・リミテッド | オキシトシン拮抗薬としての置換トリアゾール誘導体 |
CN101227892B (zh) * | 2005-04-08 | 2013-06-05 | 舌交付有限公司 | 口腔给药系统 |
JP2009504628A (ja) * | 2005-08-10 | 2009-02-05 | ファイザー・リミテッド | オキシトシン拮抗薬としての置換トリアゾール誘導体 |
EP2233472B1 (en) * | 2006-03-28 | 2014-01-15 | Atir Holding S.A. | Heterocyclic compounds and uses thereof in the treatment of sexual disorders |
US7800094B2 (en) * | 2007-06-11 | 2010-09-21 | Macronix International Co., Ltd. | Resistance memory with tungsten compound and manufacturing |
DK2442650T3 (en) | 2009-06-12 | 2015-12-07 | Cynapsus Therapeutics Inc | sublingual apomorphine |
WO2011130608A1 (en) * | 2010-04-15 | 2011-10-20 | Life Science Enhancement Corporation | Methods and compositions for enhancing female sexual arousal and treating female sexual dysfunction |
NZ612686A (en) | 2010-12-16 | 2015-11-27 | Cynapsus Therapeutics Inc | Sublingual films |
US9353067B2 (en) | 2011-04-10 | 2016-05-31 | Atir Holding S.A. | Heterocyclic compounds and uses thereof in the treatment of sexual disorders |
EP2545905A1 (en) | 2011-07-11 | 2013-01-16 | Britannia Pharmaceuticals Limited | A new therapeutical composition containing apomorphine as active ingredient |
JP7211706B2 (ja) | 2015-04-21 | 2023-01-24 | サノヴィオン ファーマシュティカルズ インコーポレーテッド | 口腔粘膜へのアポモルフィンの投与によるパーキンソン病の治療方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4521421A (en) * | 1983-09-26 | 1985-06-04 | Eli Lilly And Company | Treatment of sexual dysfunction |
EP0641202A1 (en) * | 1992-05-18 | 1995-03-08 | Smithkline Beecham Plc | Use of indolone derivatives for the treatment of memory disorders, sexual dysfunction and parkinson's disease |
US5565466A (en) * | 1993-08-13 | 1996-10-15 | Zonagen, Inc. | Methods for modulating the human sexual response |
DE69534693T2 (de) * | 1994-04-22 | 2006-08-31 | Pentech Pharmaceuticals, Inc., Wheeling | Sublinguale Zusammensetzung enthaltend Apomorphine zur Diagnose der funktionellen Impotenz |
US5562917A (en) * | 1994-12-23 | 1996-10-08 | Pentech Pharmaceuticals, Inc. | Transdermal administration of apomorphine |
US5624677A (en) * | 1995-06-13 | 1997-04-29 | Pentech Pharmaceuticals, Inc. | Controlled release of drugs delivered by sublingual or buccal administration |
US5945117A (en) * | 1998-01-30 | 1999-08-31 | Pentech Pharmaceuticals, Inc. | Treatment of female sexual dysfunction |
-
1998
- 1998-01-30 US US09/016,252 patent/US5945117A/en not_active Expired - Fee Related
-
1999
- 1999-01-21 TN TNTNSN99008A patent/TNSN99008A1/fr unknown
- 1999-01-28 EP EP99905497A patent/EP1056419A4/en not_active Withdrawn
- 1999-01-28 NZ NZ506597A patent/NZ506597A/en unknown
- 1999-01-28 HN HN1999000015A patent/HN1999000015A/es unknown
- 1999-01-28 JP JP2000529203A patent/JP2002501875A/ja not_active Withdrawn
- 1999-01-28 WO PCT/US1999/001776 patent/WO1999038467A1/en not_active Application Discontinuation
- 1999-01-28 IL IL13756999A patent/IL137569A0/xx active IP Right Grant
- 1999-01-28 PL PL99342062A patent/PL194350B1/pl unknown
- 1999-01-28 ZA ZA9900686A patent/ZA99686B/xx unknown
- 1999-01-28 CA CA002322289A patent/CA2322289A1/en not_active Abandoned
- 1999-01-28 JO JO19992085A patent/JO2085B1/en active
- 1999-01-28 HU HU0101268A patent/HUP0101268A3/hu unknown
- 1999-01-28 SK SK1136-2000A patent/SK11362000A3/sk unknown
- 1999-01-28 TR TR2000/02220T patent/TR200002220T2/xx unknown
- 1999-01-28 AU AU25644/99A patent/AU752928B2/en not_active Ceased
- 1999-01-28 CR CR5959A patent/CR5959A/es not_active Application Discontinuation
- 1999-01-28 MX MXPA00007447A patent/MXPA00007447A/es not_active IP Right Cessation
- 1999-01-28 BR BR9908038-9A patent/BR9908038A/pt not_active Application Discontinuation
- 1999-01-28 CN CNB998044423A patent/CN1250221C/zh not_active Expired - Fee Related
- 1999-01-28 KR KR1020007008333A patent/KR20010040477A/ko not_active Application Discontinuation
- 1999-01-29 PE PE1999000067A patent/PE20000240A1/es not_active Application Discontinuation
- 1999-01-29 PA PA19998467801A patent/PA8467801A1/es unknown
- 1999-01-29 MA MA25442A patent/MA26600A1/fr unknown
- 1999-01-29 TW TW088101384A patent/TW550069B/zh not_active IP Right Cessation
- 1999-01-29 AR ARP990100389A patent/AR017976A1/es not_active Application Discontinuation
- 1999-01-29 CO CO99005067A patent/CO4970819A1/es unknown
- 1999-01-29 UY UY25374A patent/UY25374A1/es not_active Application Discontinuation
- 1999-01-30 DZ DZ990015A patent/DZ2714A1/xx active
- 1999-01-31 GC GCP199973 patent/GC0000096A/xx active
- 1999-07-02 US US09/345,009 patent/US6193992B1/en not_active Expired - Fee Related
-
2000
- 2000-07-27 NO NO20003845A patent/NO319821B1/no unknown
- 2000-07-27 IL IL137569A patent/IL137569A/en unknown
- 2000-08-28 BG BG104715A patent/BG64667B1/bg unknown
-
2001
- 2001-07-20 GT GT199900013A patent/GT199900013A/es unknown
-
2002
- 2002-03-14 HK HK02101988.0A patent/HK1040901B/zh not_active IP Right Cessation
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
UY25374A1 (es) | Composiciones de apomorfina útiles en el tratamiento de disfunción sexual femenina | |
AR100291A2 (es) | Composición catártica | |
BR9302738A (pt) | Composicao oral substancialmente nao irritante,com sabor aceitavel | |
CO5271759A1 (es) | Formulacion en solucion que contiene una mezcla de disolventes | |
US20020022655A1 (en) | Leukemic cell growth inhibiting method | |
EP0151989A3 (en) | Means for the treatment of cardiac diseases | |
CO5590913A2 (es) | Terapia de combinacion antivirica | |
MD1688G2 (ro) | Benzotiofen, benzofuran şi indoltiazepinone, oxazepinone şi diazepinone, compoziţie farmaceutică, metodă de inhibare a aderării leucocitelor la celulele endoteliale pentru tratamentul proceselor inflamatorii şi metodă de tratament al mamiferelor infectate cu HIV infecţie . | |
AR015744A1 (es) | Uso de dexmedetomidina para sedacion en terapia intensiva | |
RU94044456A (ru) | Средство для подавления дисфункционального маточного кровотечения | |
KR970025615A (ko) | 암 전이 억제제 | |
ES2108240T3 (es) | Derivados de tiosemicarbazona de 2-formilpiridina, su preparacion y su uso como agentes antitumor. | |
AR006892A1 (es) | Uso de formas del acido hialuronico (ha) para el tratamiento del cancer | |
KR890004693A (ko) | 남성형 대머리와 원치 않는 모발의 성장을 치료하는 방법 | |
CO4960654A1 (es) | Metodo para el tratamiento de enfermedades fisiologicas relacionadas con el uso o con las secuelas provocadas por el uso de la cocaina u otros estimulantes psicomotores | |
PE33396A1 (es) | Composicion para el tratamiento del ansia de nicotina y/o los sintomas de abstinencia de fumar | |
AR041069A1 (es) | Composicion de tolterodina liquida oral | |
ES2105923B1 (es) | Composiciones para el tratamiento de una infeccion y una enfermedad causadas por el virus de la hepatitis b (hbv). | |
ES2039460T3 (es) | Un procedimiento para producir una solucion inyectable de glicosido de antraciclina. | |
ES2067206T3 (es) | Composiciones farmaceuticas conteniendo 3-amino-epsilon-caprolactamas para estimular el proceso de aprendizaje y la memoria. | |
CO5021217A1 (es) | Composiciones estables de mitoxantrona, procedimietno para prepararlas; utilizacion de dichas composiciones y medica- mentos que incluyen dichas soluciones para el tratamiento de enfermedades cancerosas | |
IS6555A (is) | Meðferð með aðskildum skömmtum sem hafa æðaskaðandi virkni | |
ES2111013T3 (es) | Una composicion profilactica/terapeutica que contiene ws7622a para evitar o tratar la coagulacion intravascular diseminada, la enfermedad infecciosa cronica del tracto respiratorio o la bronquitis cronica. | |
MX9302832A (es) | Nuevo medicamento para el tratamiento de la arritmia. | |
MEP1108A (en) | Use of specific dose of fondaparinux sodium for the treatment of acs |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
109 | Application deemed to be withdrawn |
Effective date: 20120117 |