US3874852A - Reagent and method for determining leukocytes and hemoglobin in the blood - Google Patents

Reagent and method for determining leukocytes and hemoglobin in the blood Download PDF

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Publication number
US3874852A
US3874852A US485931A US48593174A US3874852A US 3874852 A US3874852 A US 3874852A US 485931 A US485931 A US 485931A US 48593174 A US48593174 A US 48593174A US 3874852 A US3874852 A US 3874852A
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US
United States
Prior art keywords
ion
quaternary ammonium
reagent
chain alkyl
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
US485931A
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English (en)
Inventor
Thomas E Hamill
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beckman Coulter Diagnostics Inc
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Coulter Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23929974&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=US3874852(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Coulter Diagnostics Inc filed Critical Coulter Diagnostics Inc
Priority to US485931A priority Critical patent/US3874852A/en
Priority to NL7415233.A priority patent/NL164669B/nl
Priority to AU75725/74A priority patent/AU482810B2/en
Priority to IL46137A priority patent/IL46137A/en
Priority to ZA00747574A priority patent/ZA747574B/xx
Priority to IT54278/74A priority patent/IT1029631B/it
Priority to CH1585074A priority patent/CH588078A5/xx
Priority to JP754195A priority patent/JPS616341B2/ja
Priority to CA217,470A priority patent/CA1024868A/en
Priority to BE6044886A priority patent/BE824206A/nl
Priority to FR7500452A priority patent/FR2277344A1/fr
Priority to SE7500245A priority patent/SE415609B/xx
Priority to MX754018U priority patent/MX4259E/es
Priority to GB2184/75A priority patent/GB1489303A/en
Priority to DE2501855A priority patent/DE2501855C3/de
Priority to ES433929A priority patent/ES433929A1/es
Publication of US3874852A publication Critical patent/US3874852A/en
Publication of US3874852B1 publication Critical patent/US3874852B1/en
Application granted granted Critical
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5094—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for blood cell populations
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/721—Haemoglobin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/101666—Particle count or volume standard or control [e.g., platelet count standards, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/107497—Preparation composition [e.g., lysing or precipitation, etc.]

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Ecology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
US485931A 1974-07-05 1974-07-05 Reagent and method for determining leukocytes and hemoglobin in the blood Expired - Lifetime US3874852A (en)

Priority Applications (16)

Application Number Priority Date Filing Date Title
US485931A US3874852A (en) 1974-07-05 1974-07-05 Reagent and method for determining leukocytes and hemoglobin in the blood
NL7415233.A NL164669B (nl) 1974-07-05 1974-11-22 Werkwijze voor het bereiden van een reagens geschikt voor het bepalen van leukocyten en hemoglobine in bloed.
AU75725/74A AU482810B2 (en) 1974-07-05 1974-11-25 Reagent and method for determining leukocytes and hemoglobin inthe blood
IL46137A IL46137A (en) 1974-07-05 1974-11-27 Reagent and method for determining leukocytes and hemoglobin in the blood
ZA00747574A ZA747574B (en) 1974-07-05 1974-11-27 Reagent and method for determining leukocytes and hemoglobin in the blood
IT54278/74A IT1029631B (it) 1974-07-05 1974-11-28 Regente per determinare i leucociti e l emoglobina nel sangue
CH1585074A CH588078A5 (nl) 1974-07-05 1974-11-29
JP754195A JPS616341B2 (nl) 1974-07-05 1974-12-28
CA217,470A CA1024868A (en) 1974-07-05 1975-01-07 Reagent and method for determining leukocytes and hemoglobin in the blood
BE6044886A BE824206A (nl) 1974-07-05 1975-01-08 Werkwijze voor het bereiden van een reagens en werkwijze voor het bepalen van leukocyten en hemoglobine in bloed
FR7500452A FR2277344A1 (fr) 1974-07-05 1975-01-08 Reactif et procede pour determiner les leucocytes et l'hemoglobine dans le sang
SE7500245A SE415609B (sv) 1974-07-05 1975-01-10 Sett och reagens for bestemning av leukocyter och hemoglobin i blod
MX754018U MX4259E (es) 1974-07-05 1975-01-15 Procedimiento mejorado para obtener una composicion para la estromatolisis de eritrocitos y trombocitos en la sangre
GB2184/75A GB1489303A (en) 1974-07-05 1975-01-17 Reagent and method for determining leukocytes and hemoglobin in the blood
DE2501855A DE2501855C3 (de) 1974-07-05 1975-01-17 Reagens und Verfahren zur Bestimmung von Leukozyten und Hämoglobin im Blut
ES433929A ES433929A1 (es) 1974-07-05 1975-01-17 Perfeccionamientos introducidos en un metodo de determina- cion de leucocitos y hemoglobina en la sangre.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US485931A US3874852A (en) 1974-07-05 1974-07-05 Reagent and method for determining leukocytes and hemoglobin in the blood

Publications (2)

Publication Number Publication Date
US3874852A true US3874852A (en) 1975-04-01
US3874852B1 US3874852B1 (nl) 1989-07-11

Family

ID=23929974

Family Applications (1)

Application Number Title Priority Date Filing Date
US485931A Expired - Lifetime US3874852A (en) 1974-07-05 1974-07-05 Reagent and method for determining leukocytes and hemoglobin in the blood

Country Status (15)

Country Link
US (1) US3874852A (nl)
JP (1) JPS616341B2 (nl)
BE (1) BE824206A (nl)
CA (1) CA1024868A (nl)
CH (1) CH588078A5 (nl)
DE (1) DE2501855C3 (nl)
ES (1) ES433929A1 (nl)
FR (1) FR2277344A1 (nl)
GB (1) GB1489303A (nl)
IL (1) IL46137A (nl)
IT (1) IT1029631B (nl)
MX (1) MX4259E (nl)
NL (1) NL164669B (nl)
SE (1) SE415609B (nl)
ZA (1) ZA747574B (nl)

Cited By (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4102810A (en) * 1975-01-13 1978-07-25 Coulter Electronics, Inc. Stabilized hematological reagent solutions
US4141856A (en) * 1976-05-24 1979-02-27 Dorwart Jr William V Reference material for establishing anion concentrations in analytical chemistry tests
US4185964A (en) * 1977-02-08 1980-01-29 Central Laboratories of Associated Maryland Pathologists, Ltd. Lysing reagent
US4219440A (en) * 1979-06-06 1980-08-26 Coulter Electronics, Inc. Multiple analysis hematology reference control reagent and method of making the same
EP0014929A1 (de) * 1979-02-14 1980-09-03 Roche Diagnostics GmbH Diagnostisches Mittel, Verfahren zu dessen Herstellung sowie dessen Verwendung zum Nachweis von Leukozyten in Körperflüssigkeiten
US4286963A (en) * 1979-11-23 1981-09-01 Coulter Electronics, Inc. Differential lymphoid-myeloid determination of leukocytes in whole blood
DE3123669A1 (de) * 1980-06-16 1982-04-22 Coulter Electronics, Inc., 33010 Hialeah, Fla. Verfahren, mehrzweckblutverduennungsmittel und verfahren, reagens zur differentiellen bestimmung der lymphoiden-myeloiden population von leukozyten
US4455376A (en) * 1979-09-17 1984-06-19 R. J. Harvey Instrument Corp. Photometric methods for counting the particulate components of blood
WO1984002777A1 (en) * 1983-01-03 1984-07-19 Coulter Electronics Method for the volumetric differential of leukocytes
WO1984003771A1 (en) * 1983-03-25 1984-09-27 Coulter Electronics Method and stromatolysing reagent for the volumetric determination of populations of leukocytes
WO1984004969A1 (en) * 1983-06-06 1984-12-20 Coulter Electronics Reagent for combined diluting and lysing whole blood
EP0136058A2 (en) * 1983-08-22 1985-04-03 Ortho Diagnostic Systems Inc. Flow cytometry lysing reagent with leukoprotective agent for producing a 3-part WBC count
US4521518A (en) * 1980-06-16 1985-06-04 Coulter Electronics, Inc. Multi-purpose blood diluent and lysing agent for differential determination of lymphoid-myeloid population of leukocytes
US4526869A (en) * 1980-09-24 1985-07-02 Regents Of The University Of Minnesota Method for quantitatively determining the concentration of hemoglobin in a biological sample
US4543336A (en) * 1982-02-12 1985-09-24 Dragerwerk Aktiengesellschaft Indicator for determining sulfur dioxide
WO1985005640A1 (en) * 1984-05-31 1985-12-19 Coulter Electronics, Inc. A reagent system and method for identification, enumeration and examination of classes and subclasses of blood leukocytes
US4617275A (en) * 1983-09-29 1986-10-14 Toa Medical Electronics Co., Ltd. Reagent for blood analysis
FR2582103A1 (fr) * 1985-03-19 1986-11-21 Canavaggio Michel Procede de determination d'une substance biologique dans un echantillon
US4725555A (en) * 1986-10-22 1988-02-16 Helena Laboratories Corporation Zinc protoporphyrin test system
US4745071A (en) * 1985-09-05 1988-05-17 Sequoia-Turner Corporation Method for the volumetric differentiation of blood cells types
WO1988007187A1 (en) * 1987-03-13 1988-09-22 Coulter Electronics, Inc. System for isolating and identifying leukocytes
US4853338A (en) * 1987-05-20 1989-08-01 Technicon Instruments Corporation Cyanide-free hemoglobin reagent
US4962038A (en) * 1980-06-16 1990-10-09 Coulter Electronics, Inc. Multi-purpose blood diluent and lysing agent for differential determination of lymphoid-myeloid population of leukocytes
US5008202A (en) * 1988-11-29 1991-04-16 Sequoia Turner Corporation Blood diluent for red blood cell analysis
US5045474A (en) * 1987-05-28 1991-09-03 Sequoia-Turner Corporation (Unipath) Semi-automatic process for white cell differential count
US5155044A (en) * 1987-03-13 1992-10-13 Coulter Electronics, Inc. Lysing reagent system for isolation, identification and/or analysis of leukocytes from whole blood samples
US5284940A (en) * 1990-11-14 1994-02-08 Hri Research, Inc. Preparation for nucleic acid samples
US5510267A (en) * 1989-05-15 1996-04-23 Abbott Laboratories Flow cytometry lytic agent and method enabling 5-part leukocyte differential count
US5620852A (en) * 1990-11-14 1997-04-15 Hri Research, Inc. Nucleic acid preparation methods
US5654179A (en) * 1990-11-14 1997-08-05 Hri Research, Inc. Nucleic acid preparation methods
US5834315A (en) * 1994-12-23 1998-11-10 Coulter Corporation Cyanide-free reagent and method for hemoglobin determination and leukocyte differentitation
EP0878715A1 (en) * 1997-05-13 1998-11-18 Bayer Corporation Cyanide-containing hemoglobin reagent composition and method providing acceptable precision, accuracy and freedom from white cell interference on automated hematology analyzers
US5958781A (en) * 1994-07-14 1999-09-28 Abbott Laboratories Methods and reagents for cyanide-free determination of hemoglobin and leukocytes in whole blood
US20040241769A1 (en) * 1999-09-24 2004-12-02 Crews Harold Richardson Multi-purpose reagent system and method for enumeration of red blood cells, white blood cells and thrombocytes and differential determination of white blood cells
US20050106713A1 (en) * 2003-09-03 2005-05-19 Phan Brigitte C. Personal diagnostic devices and related methods
WO2014006638A1 (en) 2012-07-03 2014-01-09 Srivastava Ambar Device and method for blood hemoglobin measurement without carboxyhemoglobin interference
US9091677B2 (en) 2010-08-09 2015-07-28 Beckman Coulter, Inc. Isotonic buffered composition and method that enables counting of cells
US9523676B2 (en) 2011-08-24 2016-12-20 Eiken Kagaku Kabushiki Kaisha Leukocyte measurement device and reagent kit
CN113959911A (zh) * 2020-07-20 2022-01-21 深圳迈瑞生物医疗电子股份有限公司 抗血小板聚集干扰的检测方法、试剂及其应用

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3024835A1 (de) * 1980-07-01 1982-01-28 Bayer Ag, 5090 Leverkusen Reagenz fuer die haemoglobinbestimmung

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3546131A (en) * 1968-07-05 1970-12-08 Uni Tech Chem Mfg Co Stabilized cyanmethemoglobin reagent containing ferricyanide,cyanide and polyvinylpyrrolidone
US3607695A (en) * 1969-02-14 1971-09-21 Pfizer & Co C Hemoglobinopathy controls
US3663175A (en) * 1970-10-05 1972-05-16 Bio Dynamics Inc Method of determining hemoglobin in blood

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE790042A (nl) * 1971-10-14 1973-04-13 Coulter Electronics Werkwijze voor het classifiseren van deeltjes

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3546131A (en) * 1968-07-05 1970-12-08 Uni Tech Chem Mfg Co Stabilized cyanmethemoglobin reagent containing ferricyanide,cyanide and polyvinylpyrrolidone
US3607695A (en) * 1969-02-14 1971-09-21 Pfizer & Co C Hemoglobinopathy controls
US3663175A (en) * 1970-10-05 1972-05-16 Bio Dynamics Inc Method of determining hemoglobin in blood

Cited By (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4102810A (en) * 1975-01-13 1978-07-25 Coulter Electronics, Inc. Stabilized hematological reagent solutions
US4141856A (en) * 1976-05-24 1979-02-27 Dorwart Jr William V Reference material for establishing anion concentrations in analytical chemistry tests
US4185964A (en) * 1977-02-08 1980-01-29 Central Laboratories of Associated Maryland Pathologists, Ltd. Lysing reagent
EP0014929A1 (de) * 1979-02-14 1980-09-03 Roche Diagnostics GmbH Diagnostisches Mittel, Verfahren zu dessen Herstellung sowie dessen Verwendung zum Nachweis von Leukozyten in Körperflüssigkeiten
US4219440A (en) * 1979-06-06 1980-08-26 Coulter Electronics, Inc. Multiple analysis hematology reference control reagent and method of making the same
US4455376A (en) * 1979-09-17 1984-06-19 R. J. Harvey Instrument Corp. Photometric methods for counting the particulate components of blood
US4286963A (en) * 1979-11-23 1981-09-01 Coulter Electronics, Inc. Differential lymphoid-myeloid determination of leukocytes in whole blood
GB2147999A (en) * 1980-06-16 1985-05-22 Coulter Electronics Lysing reagent for differential determination of lymphoid-myeloid population of leukocytes
DE3123669A1 (de) * 1980-06-16 1982-04-22 Coulter Electronics, Inc., 33010 Hialeah, Fla. Verfahren, mehrzweckblutverduennungsmittel und verfahren, reagens zur differentiellen bestimmung der lymphoiden-myeloiden population von leukozyten
US4962038A (en) * 1980-06-16 1990-10-09 Coulter Electronics, Inc. Multi-purpose blood diluent and lysing agent for differential determination of lymphoid-myeloid population of leukocytes
DE3153618C2 (nl) * 1980-06-16 1992-10-15 Coulter Electronics, Inc., Hialeah, Fla., Us
US4346018A (en) * 1980-06-16 1982-08-24 Coulter Electronics, Inc. Multi-purpose blood diluent and lysing agent for differential determination of lymphoid-myeloid population of leukocytes
US4521518A (en) * 1980-06-16 1985-06-04 Coulter Electronics, Inc. Multi-purpose blood diluent and lysing agent for differential determination of lymphoid-myeloid population of leukocytes
US4526869A (en) * 1980-09-24 1985-07-02 Regents Of The University Of Minnesota Method for quantitatively determining the concentration of hemoglobin in a biological sample
US4543336A (en) * 1982-02-12 1985-09-24 Dragerwerk Aktiengesellschaft Indicator for determining sulfur dioxide
US4528274A (en) * 1982-07-06 1985-07-09 Coulter Electronics, Inc. Multi-purpose blood diluent and lysing agent for differential determination of lymphoid-myeloid population of leukocytes
US4485175A (en) * 1983-01-03 1984-11-27 Coulter Electronics, Inc. Method for three-volume differential determination of lymphocyte, monocyte and granulocyte populations of leukocytes
DE3390432C2 (nl) * 1983-01-03 1988-09-01 Coulter Electronics
WO1984002777A1 (en) * 1983-01-03 1984-07-19 Coulter Electronics Method for the volumetric differential of leukocytes
WO1984003771A1 (en) * 1983-03-25 1984-09-27 Coulter Electronics Method and stromatolysing reagent for the volumetric determination of populations of leukocytes
US4529705A (en) * 1983-06-06 1985-07-16 Coulter Electronics, Inc. Reagent for combined diluting and lysing whole blood
WO1984004969A1 (en) * 1983-06-06 1984-12-20 Coulter Electronics Reagent for combined diluting and lysing whole blood
EP0136058A2 (en) * 1983-08-22 1985-04-03 Ortho Diagnostic Systems Inc. Flow cytometry lysing reagent with leukoprotective agent for producing a 3-part WBC count
US4637986A (en) * 1983-08-22 1987-01-20 Ortho Diagnostic Systems, Inc. Flow cytometry lysing reagent with leukoprotective agent for producing a 3-part WBC count
EP0136058A3 (en) * 1983-08-22 1987-04-22 Ortho Diagnostic Systems Inc. Flow cytometry lysing reagent with leukoprotective agent for producing a 3-part wbc count
US4656139A (en) * 1983-09-29 1987-04-07 Toa Medical Electronics Co., Ltd. Method for preparing cells for blood analysis
US4617275A (en) * 1983-09-29 1986-10-14 Toa Medical Electronics Co., Ltd. Reagent for blood analysis
WO1985005640A1 (en) * 1984-05-31 1985-12-19 Coulter Electronics, Inc. A reagent system and method for identification, enumeration and examination of classes and subclasses of blood leukocytes
FR2582103A1 (fr) * 1985-03-19 1986-11-21 Canavaggio Michel Procede de determination d'une substance biologique dans un echantillon
US4745071A (en) * 1985-09-05 1988-05-17 Sequoia-Turner Corporation Method for the volumetric differentiation of blood cells types
EP0268376A3 (en) * 1986-10-22 1990-07-11 Helena Laboratories Corporation Blood sample modification and reagent compositions therefor
EP0268376A2 (en) * 1986-10-22 1988-05-25 Helena Laboratories Corporation Blood sample modification and reagent compositions therefor
US4725555A (en) * 1986-10-22 1988-02-16 Helena Laboratories Corporation Zinc protoporphyrin test system
US5731206A (en) * 1987-03-13 1998-03-24 Coulter Electronics, Inc. Method and reagent system for isolation, identification and/or analysis of leukocytes from whole blood samples
WO1988007187A1 (en) * 1987-03-13 1988-09-22 Coulter Electronics, Inc. System for isolating and identifying leukocytes
US5155044A (en) * 1987-03-13 1992-10-13 Coulter Electronics, Inc. Lysing reagent system for isolation, identification and/or analysis of leukocytes from whole blood samples
US4853338A (en) * 1987-05-20 1989-08-01 Technicon Instruments Corporation Cyanide-free hemoglobin reagent
US5045474A (en) * 1987-05-28 1991-09-03 Sequoia-Turner Corporation (Unipath) Semi-automatic process for white cell differential count
US5008202A (en) * 1988-11-29 1991-04-16 Sequoia Turner Corporation Blood diluent for red blood cell analysis
US5510267A (en) * 1989-05-15 1996-04-23 Abbott Laboratories Flow cytometry lytic agent and method enabling 5-part leukocyte differential count
US5620852A (en) * 1990-11-14 1997-04-15 Hri Research, Inc. Nucleic acid preparation methods
US5654179A (en) * 1990-11-14 1997-08-05 Hri Research, Inc. Nucleic acid preparation methods
US5284940A (en) * 1990-11-14 1994-02-08 Hri Research, Inc. Preparation for nucleic acid samples
US5958781A (en) * 1994-07-14 1999-09-28 Abbott Laboratories Methods and reagents for cyanide-free determination of hemoglobin and leukocytes in whole blood
US6740527B1 (en) 1994-07-14 2004-05-25 Abbott Laboratories Methods and reagents for cyanide-free determination of hemoglobin and leukocytes in whole blood
US5834315A (en) * 1994-12-23 1998-11-10 Coulter Corporation Cyanide-free reagent and method for hemoglobin determination and leukocyte differentitation
EP0878715A1 (en) * 1997-05-13 1998-11-18 Bayer Corporation Cyanide-containing hemoglobin reagent composition and method providing acceptable precision, accuracy and freedom from white cell interference on automated hematology analyzers
US5858794A (en) * 1997-05-13 1999-01-12 Bayer Corporation Cyanide-containing hemoglobin reagent composition and method providing acceptable precision, accuracy and freedom from white cell interference on automated hematology analyzers
US20040241769A1 (en) * 1999-09-24 2004-12-02 Crews Harold Richardson Multi-purpose reagent system and method for enumeration of red blood cells, white blood cells and thrombocytes and differential determination of white blood cells
US20050106713A1 (en) * 2003-09-03 2005-05-19 Phan Brigitte C. Personal diagnostic devices and related methods
WO2005084534A1 (en) 2003-09-03 2005-09-15 Life Patch International, Inc. Personal diagnostic devices and related methods
US9133024B2 (en) 2003-09-03 2015-09-15 Brigitte Chau Phan Personal diagnostic devices including related methods and systems
US9993189B2 (en) 2003-09-03 2018-06-12 Life Patch International Personal diagnostic device having a fluidic circuit with a plurality of analysis chambers
US11737694B2 (en) 2003-09-03 2023-08-29 Life Patch International, Inc. Personal diagnostic device having a plurality of tubules
US9091677B2 (en) 2010-08-09 2015-07-28 Beckman Coulter, Inc. Isotonic buffered composition and method that enables counting of cells
US9567622B2 (en) 2010-08-09 2017-02-14 Beckman Coulter, Inc. Isotonic buffered composition and method that enables counting of cells
US9523676B2 (en) 2011-08-24 2016-12-20 Eiken Kagaku Kabushiki Kaisha Leukocyte measurement device and reagent kit
WO2014006638A1 (en) 2012-07-03 2014-01-09 Srivastava Ambar Device and method for blood hemoglobin measurement without carboxyhemoglobin interference
CN113959911A (zh) * 2020-07-20 2022-01-21 深圳迈瑞生物医疗电子股份有限公司 抗血小板聚集干扰的检测方法、试剂及其应用

Also Published As

Publication number Publication date
SE7500245L (sv) 1976-01-07
IT1029631B (it) 1979-03-20
BE824206A (nl) 1975-07-08
IL46137A0 (en) 1975-02-10
CA1024868A (en) 1978-01-24
AU7572574A (en) 1976-05-27
NL7415233A (nl) 1976-01-07
CH588078A5 (nl) 1977-05-31
ZA747574B (en) 1976-07-28
MX4259E (es) 1982-03-08
GB1489303A (en) 1977-10-19
DE2501855B2 (de) 1980-02-07
DE2501855C3 (de) 1980-10-16
JPS516788A (nl) 1976-01-20
JPS616341B2 (nl) 1986-02-25
ES433929A1 (es) 1976-11-16
US3874852B1 (nl) 1989-07-11
IL46137A (en) 1977-02-28
NL164669B (nl) 1980-08-15
FR2277344B1 (nl) 1977-11-18
DE2501855A1 (de) 1976-01-22
FR2277344A1 (fr) 1976-01-30
SE415609B (sv) 1980-10-13

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