GB1489303A - Reagent and method for determining leukocytes and hemoglobin in the blood - Google Patents

Reagent and method for determining leukocytes and hemoglobin in the blood

Info

Publication number
GB1489303A
GB1489303A GB2184/75A GB218475A GB1489303A GB 1489303 A GB1489303 A GB 1489303A GB 2184/75 A GB2184/75 A GB 2184/75A GB 218475 A GB218475 A GB 218475A GB 1489303 A GB1489303 A GB 1489303A
Authority
GB
United Kingdom
Prior art keywords
reagent
blood
hemoglobin
leukocytes
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2184/75A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beckman Coulter Diagnostics Inc
Original Assignee
Coulter Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23929974&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GB1489303(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Coulter Diagnostics Inc filed Critical Coulter Diagnostics Inc
Publication of GB1489303A publication Critical patent/GB1489303A/en
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5094—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for blood cell populations
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/721—Haemoglobin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/101666—Particle count or volume standard or control [e.g., platelet count standards, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/107497—Preparation composition [e.g., lysing or precipitation, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Ecology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)

Abstract

1489303 Reagent for blood COULTER DIAGNOSTICS Inc 17 Jan 1975 [5 July 1974] 2184/75 Heading G1B A reagent for leukocytes and haemoglobin in blood comprises a ferricyanide free aqueous solution of 0À0006-0À005 M CN- and NR 4 + (3 short chain and one long chain alkyl groups) the latter being provided by dissolving 0À5-10 wt. per cent of a salt in the solution. The salt is preferably a halide, sulphate, phosphate, or nitrate and the cyanide an alkali metal cyanide. In use blood is diluted and mixed with reagent (blood: reagent # 1:8À6).
GB2184/75A 1974-07-05 1975-01-17 Reagent and method for determining leukocytes and hemoglobin in the blood Expired GB1489303A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US485931A US3874852A (en) 1974-07-05 1974-07-05 Reagent and method for determining leukocytes and hemoglobin in the blood

Publications (1)

Publication Number Publication Date
GB1489303A true GB1489303A (en) 1977-10-19

Family

ID=23929974

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2184/75A Expired GB1489303A (en) 1974-07-05 1975-01-17 Reagent and method for determining leukocytes and hemoglobin in the blood

Country Status (15)

Country Link
US (1) US3874852A (en)
JP (1) JPS616341B2 (en)
BE (1) BE824206A (en)
CA (1) CA1024868A (en)
CH (1) CH588078A5 (en)
DE (1) DE2501855C3 (en)
ES (1) ES433929A1 (en)
FR (1) FR2277344A1 (en)
GB (1) GB1489303A (en)
IL (1) IL46137A (en)
IT (1) IT1029631B (en)
MX (1) MX4259E (en)
NL (1) NL164669B (en)
SE (1) SE415609B (en)
ZA (1) ZA747574B (en)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3962125A (en) * 1975-01-13 1976-06-08 Coulter Diagnostics, Inc. Multi-purpose diluent for use in blood analysis by electronic instrumentation of the coulter type
US4141856A (en) * 1976-05-24 1979-02-27 Dorwart Jr William V Reference material for establishing anion concentrations in analytical chemistry tests
US4185964A (en) * 1977-02-08 1980-01-29 Central Laboratories of Associated Maryland Pathologists, Ltd. Lysing reagent
US4219440A (en) * 1979-06-06 1980-08-26 Coulter Electronics, Inc. Multiple analysis hematology reference control reagent and method of making the same
DE2905531A1 (en) * 1979-02-14 1981-01-08 Boehringer Mannheim Gmbh DIAGNOSTIC AGENT FOR DETECTING LEUCOCYTES IN BODY LIQUIDS
US4455376A (en) * 1979-09-17 1984-06-19 R. J. Harvey Instrument Corp. Photometric methods for counting the particulate components of blood
US4286963A (en) * 1979-11-23 1981-09-01 Coulter Electronics, Inc. Differential lymphoid-myeloid determination of leukocytes in whole blood
US4346018A (en) * 1980-06-16 1982-08-24 Coulter Electronics, Inc. Multi-purpose blood diluent and lysing agent for differential determination of lymphoid-myeloid population of leukocytes
US4962038A (en) * 1980-06-16 1990-10-09 Coulter Electronics, Inc. Multi-purpose blood diluent and lysing agent for differential determination of lymphoid-myeloid population of leukocytes
US4521518A (en) * 1980-06-16 1985-06-04 Coulter Electronics, Inc. Multi-purpose blood diluent and lysing agent for differential determination of lymphoid-myeloid population of leukocytes
DE3024835A1 (en) * 1980-07-01 1982-01-28 Bayer Ag, 5090 Leverkusen REAGENT FOR HEMOGLOBIN DETERMINATION
US4526869A (en) * 1980-09-24 1985-07-02 Regents Of The University Of Minnesota Method for quantitatively determining the concentration of hemoglobin in a biological sample
DE3204938C2 (en) * 1982-02-12 1985-01-17 Drägerwerk AG, 2400 Lübeck Indicator for the determination of sulfur dioxide
US4528274A (en) * 1982-07-06 1985-07-09 Coulter Electronics, Inc. Multi-purpose blood diluent and lysing agent for differential determination of lymphoid-myeloid population of leukocytes
US4485175A (en) * 1983-01-03 1984-11-27 Coulter Electronics, Inc. Method for three-volume differential determination of lymphocyte, monocyte and granulocyte populations of leukocytes
US4529705A (en) * 1983-06-06 1985-07-16 Coulter Electronics, Inc. Reagent for combined diluting and lysing whole blood
US4637986A (en) * 1983-08-22 1987-01-20 Ortho Diagnostic Systems, Inc. Flow cytometry lysing reagent with leukoprotective agent for producing a 3-part WBC count
JPS6073356A (en) * 1983-09-29 1985-04-25 Toa Medical Electronics Co Ltd Reagent for blood analysis
JPS61502280A (en) * 1984-05-31 1986-10-09 ク−ルタ−・エレクトロニクス・インコ−ポレ−テッド Methods for identifying, counting, and testing leukocyte classes and subclasses, and reagent systems used therefor
FR2582103B1 (en) * 1985-03-19 1989-05-05 Canavaggio Michel METHOD FOR DETERMINING A BIOLOGICAL SUBSTANCE IN A SAMPLE
US4745071A (en) * 1985-09-05 1988-05-17 Sequoia-Turner Corporation Method for the volumetric differentiation of blood cells types
US4725555A (en) * 1986-10-22 1988-02-16 Helena Laboratories Corporation Zinc protoporphyrin test system
IL85532A (en) * 1987-03-13 1992-03-29 Coulter Electronics Method and lytic reagent system for isolation,identification and/or analysis of leukocytes from whole blood samples
US5155044A (en) * 1987-03-13 1992-10-13 Coulter Electronics, Inc. Lysing reagent system for isolation, identification and/or analysis of leukocytes from whole blood samples
US4853338A (en) * 1987-05-20 1989-08-01 Technicon Instruments Corporation Cyanide-free hemoglobin reagent
US5045474A (en) * 1987-05-28 1991-09-03 Sequoia-Turner Corporation (Unipath) Semi-automatic process for white cell differential count
US5008202A (en) * 1988-11-29 1991-04-16 Sequoia Turner Corporation Blood diluent for red blood cell analysis
CA2016699C (en) * 1989-05-15 2003-11-18 Paul N. Marshall Lytic agents and uses thereof
US5654179A (en) * 1990-11-14 1997-08-05 Hri Research, Inc. Nucleic acid preparation methods
US5284940A (en) * 1990-11-14 1994-02-08 Hri Research, Inc. Preparation for nucleic acid samples
US5620852A (en) * 1990-11-14 1997-04-15 Hri Research, Inc. Nucleic acid preparation methods
AU3094695A (en) 1994-07-14 1996-02-16 Abbott Laboratories Methods and reagents for cyanide-free determination of hemoglobin and leukocytes in whole blood
US5834315A (en) * 1994-12-23 1998-11-10 Coulter Corporation Cyanide-free reagent and method for hemoglobin determination and leukocyte differentitation
US5858794A (en) * 1997-05-13 1999-01-12 Bayer Corporation Cyanide-containing hemoglobin reagent composition and method providing acceptable precision, accuracy and freedom from white cell interference on automated hematology analyzers
US20020098589A1 (en) * 2001-01-19 2002-07-25 Crews Harold Richardson Multi-purpose reagent system and method for enumeration of red blood cells, white blood cells and thrombocytes and differential determination of white blood cells
EP1670356A1 (en) 2003-09-03 2006-06-21 Life Patch International, Inc. Personal diagnostic devices and related methods
US9091677B2 (en) 2010-08-09 2015-07-28 Beckman Coulter, Inc. Isotonic buffered composition and method that enables counting of cells
JP5986089B2 (en) 2011-08-24 2016-09-06 栄研化学株式会社 Leukocyte measurement device and reagent kit
IN2012DE02074A (en) 2012-07-03 2015-08-14 Srivastava Ambar
CN113959911B (en) * 2020-07-20 2024-06-18 深圳迈瑞生物医疗电子股份有限公司 Detection method and reagent for resisting platelet aggregation interference and application of detection method and reagent

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3546131A (en) * 1968-07-05 1970-12-08 Uni Tech Chem Mfg Co Stabilized cyanmethemoglobin reagent containing ferricyanide,cyanide and polyvinylpyrrolidone
US3607695A (en) * 1969-02-14 1971-09-21 Pfizer & Co C Hemoglobinopathy controls
US3663175A (en) * 1970-10-05 1972-05-16 Bio Dynamics Inc Method of determining hemoglobin in blood
BE790042A (en) * 1971-10-14 1973-04-13 Coulter Electronics METHOD FOR CLASSIFYING PARTICLES

Also Published As

Publication number Publication date
DE2501855A1 (en) 1976-01-22
MX4259E (en) 1982-03-08
DE2501855B2 (en) 1980-02-07
IL46137A0 (en) 1975-02-10
US3874852B1 (en) 1989-07-11
IT1029631B (en) 1979-03-20
FR2277344B1 (en) 1977-11-18
JPS616341B2 (en) 1986-02-25
CH588078A5 (en) 1977-05-31
AU7572574A (en) 1976-05-27
SE415609B (en) 1980-10-13
DE2501855C3 (en) 1980-10-16
IL46137A (en) 1977-02-28
BE824206A (en) 1975-07-08
ES433929A1 (en) 1976-11-16
NL164669B (en) 1980-08-15
FR2277344A1 (en) 1976-01-30
US3874852A (en) 1975-04-01
ZA747574B (en) 1976-07-28
SE7500245L (en) 1976-01-07
JPS516788A (en) 1976-01-20
NL7415233A (en) 1976-01-07
CA1024868A (en) 1978-01-24

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PE20 Patent expired after termination of 20 years

Effective date: 19950116