US20180282040A1 - Individual blister packs for optimized stacking - Google Patents

Individual blister packs for optimized stacking Download PDF

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Publication number
US20180282040A1
US20180282040A1 US15/761,737 US201615761737A US2018282040A1 US 20180282040 A1 US20180282040 A1 US 20180282040A1 US 201615761737 A US201615761737 A US 201615761737A US 2018282040 A1 US2018282040 A1 US 2018282040A1
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United States
Prior art keywords
individual
stack
bubble
main body
blister
Prior art date
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Abandoned
Application number
US15/761,737
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English (en)
Inventor
Stefan Bracht
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Bayer Pharma AG
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Bayer Pharma AG
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Publication date
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Assigned to BAYER PHARMA AKTIENGESELLSCHAFT reassignment BAYER PHARMA AKTIENGESELLSCHAFT ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: BRACHT, STEFAN
Publication of US20180282040A1 publication Critical patent/US20180282040A1/en
Abandoned legal-status Critical Current

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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/28—Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
    • B65D75/30—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • B65D75/32—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
    • B65D75/325—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet being recessed, and the other being a flat not- rigid sheet, e.g. puncturable or peelable foil
    • B65D75/326—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet being recessed, and the other being a flat not- rigid sheet, e.g. puncturable or peelable foil and forming one compartment
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/28—Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
    • B65D75/30—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • B65D75/32—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
    • B65D75/36—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet or blank being recessed and the other formed of relatively stiff flat sheet material, e.g. blister packages, the recess or recesses being preformed
    • B65D75/366—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet or blank being recessed and the other formed of relatively stiff flat sheet material, e.g. blister packages, the recess or recesses being preformed and forming one compartment
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00—Containers or packages with special means for dispensing contents
    • B65D83/04—Containers or packages with special means for dispensing contents for dispensing annular, disc-shaped, or spherical or like small articles, e.g. tablets or pills
    • B65D83/0445—Containers or packages with special means for dispensing contents for dispensing annular, disc-shaped, or spherical or like small articles, e.g. tablets or pills all the articles being stored in individual compartments
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D2575/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes or webs of flexible sheet material, e.g. in folded wrappers
    • B65D2575/28—Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by association or interconnecting two or more sheets or blanks
    • B65D2575/30—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • B65D2575/32—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
    • B65D2575/3209—Details
    • B65D2575/3263—Means or construction allowing stacking, bundling or interfitting of packages

Definitions

  • the present invention relates to individual blister packs, methods for production thereof, stack-like arrangements containing individual blister packs of this type, and boxes containing stack-like arrangements of individual blister packs.
  • Blister packs have long been known.
  • Medicinal product portions such as tablets and capsules, are preferably supplied in blister packaging as primary packaging.
  • the tablets or capsules are present in an arrangement of individual indentations (bubbles).
  • the indentations are usually sealed by an aluminium foil.
  • the medicinal product portions can be removed individually and are protected against dirt and air moisture.
  • a further advantage of medicinal product portions in blister packs lies in the easy identification of the remaining number of available medicinal product portions.
  • FIG. 1a of the laid-open application GB2184086A 15 individual medicinal product portions are provided in a planar arrangement of approximately 6-8 cm ⁇ 4-6 cm.
  • Blister packs are typically introduced into yet a further packaging before being passed on to the patient.
  • This secondary packaging is typically a folding box which, besides a number of approximately 1 to 10 blister packs, usually also contains a package leaflet containing use and safety information.
  • the secondary packaging prevents a shifting of blister packs stacked on top of one another. It is required essentially only for transport and is accrued by the user as waste.
  • the secondary packaging is also comparatively voluminous.
  • DE 10044118 A1 discloses a blister pack, which, besides the indentations for receiving medicinal product portions, additionally has centring nubs, which extend beyond the underside of the indentations.
  • the blister pack additionally has supporting nubs, which likewise protrude beyond the underside of the indentations.
  • Perforations are disposed in the cover, in the region of each centring nub, such that, when the blister packs are stacked in alignment, each centring nub of a blister strip rests against a perforation of the blister strip disposed beneath. If a stack of blister packs of this type is pressed together, the centring nubs destroy the perforations disposed beneath, and the centring nubs protrude into the resultant openings.
  • the blister packs are thus centred relative to one another in the horizontal plane in an interlocking manner.
  • the supporting nubs rest against the cover film of the blister strip disposed beneath, such that the blister strips are supported against one another. Since the blister packs stacked above one another cannot shift relative to one another, it is possible to dispense with a complex surrounding packaging, or such packaging can be formed in a very simple manner.
  • it is disadvantageous that, as a result of the described stacking, there is no volume reduction of the surrounding packaging compared with a stacking of similar blister strips without centring nubs.
  • an individual blister strip cannot be easily removed from the surrounding packaging; it must first be removed from the stack, which is possible only in one direction.
  • DE 19680564 T1 discloses a foldable blister strip. It has two parallel rows of bubbles, which are offset relative to one another in such a way that the bubbles in one row enter the gaps between the bubbles in the other row when the blister strip is folded.
  • the folded blister strip thus takes up less space compared with when the rows of bubbles are stacked above one another in the conventional manner.
  • the folded blister strip must first be removed from the surrounding packaging and unfolded, which is comparatively laborious.
  • a similar foldable blister pack is also disclosed in DE 29780456 U1.
  • the previously described blister packs contain more than one medicinal product portion.
  • a patient generally takes just an individual medicinal product portion at the time at which said medicinal product portion is to be taken. If, for example, the patient must take a medicinal product portion every day, the patient will gradually empty the blister pack by removing an individual medicinal product portion each day.
  • a patient often carries with them a blister strip containing a plurality of medicinal product portions, for example in order to have ready a medicinal product portion as required and/or in order to be reminded to take said medicinal product portion regularly.
  • blister strips are offered which have perforations so as to be able to separate off individual bubbles containing medicinal product portions (see, for example, EP 679587 A1). It is thus possible for the patient to carry with them only the amount of medicinal product portions actually used. It is also possible to give packaged medicinal product portions to a patient in a hospital or a resident in a care home.
  • these blister units generally do not have the complete information concerning the content, since the labelling on the rear side of a blister strip is usually destroyed by separating off individual blister units.
  • the cover film can tear.
  • blister strips having a fixed number of a plurality of medicinal product portions limit flexibility.
  • a blister strip contains 10 medicinal product portions, only packs containing this number or a multiple thereof (20, 30, etc.) can be offered.
  • the problem forming the basis of the present invention is therefore that of providing medicinal product portions in packaged form that allows a greater degree of flexibility and reliability when it comes to provision and handling, and at the same time is space-saving and resource-saving.
  • a first subject of the invention is a stack-like arrangement of N individual blister packs, where N is an integer greater than 1,
  • each single individual blister pack comprising
  • a medicinal product portion is understood to mean a solid administration form of a medicinal product that can be taken by a patient as an individual unit.
  • Examples of medicinal product portions are tablets, pills, lozenges and capsules.
  • An individual blister pack is understood to mean a combination of an individual blister packaging and a medicinal product portion or a plurality of medicinal product portions.
  • One or more medicinal product portions is/are packaged in the individual blister packaging and together with this individual blister packaging form an individual blister pack containing one or more medicinal product portions, or an individual blister for short.
  • the term “individual” relates to the number of bubbles. An individual blister is therefore a unit having an individual bubble. Synonymous terms that are used in the prior art instead of the term bubble are cavity and indentation, for example.
  • the individual blister packaging comprises a planar main body.
  • the planar main body usually consists of a film layer.
  • a further film layer referred to here as the cover film serves to seal the bubble.
  • a planar body is understood to mean a body that, in two of the three spatial directions in a Cartesian coordinate system, has a greater extent than in the third spatial direction. If it is imagined that the bubble is not there and if it is assumed that the main body does not have any curvature, the extent in the third spatial direction (z-direction, thickness of the film layer) is only a fraction of the extent in the two other spatial directions (x- and y-direction).
  • the thickness of the film layer d G is preferably less than a tenth of the extent in the orthogonal spatial directions extending perpendicularly to the thickness (x- and y-direction), particularly preferably less than a twentieth.
  • the planar main body preferably has no curvature or only a slight curvature.
  • the radius of curvature is at least 10 times the extent in the x- and/or y-direction. In a particularly preferred embodiment the radius of curvature is at least 20 times the extent in the x- and/or y-direction. In an even more particularly preferred embodiment the radius of curvature is at least 50 times the extent in the x- and/or y-direction.
  • planar main body always has a certain curvature, even if the objective is to form the main body (with the exception of the bubble) as flat as possible.
  • the introduction of the bubble into the main body which is usually implemented by thermoforming, can cause stresses in the main body, which lead to a curvature.
  • curvatures can be introduced into the main body by the mechanical processing, such as printing, cutting, gripping (for example during transport), etc.
  • the application of the cover film also constitutes a mechanical loading, which can lead to a deformation.
  • an ideal, uncurved main body is assumed in the present description. However, this is only so as to be able to better present the invention and is not to be understood as a limitation of the invention.
  • the planar main body can assume a wide variety of forms. It can assume a circular, oval, triangular, quadrangular (for example rectangular or square), pentagonal, hexagonal and further basic forms in the xy plane, and the corners can be rounded in each case.
  • the planar main body preferably has a square, rectangular or angular basic form in the xy plane, however the corners can be rounded.
  • the term “angular” is explained in greater detail further below.
  • the corners of the planar main body are preferably rounded in order to avoid injury to the individuals handling the individual blisters and/or in order to avoid damage to materials with which the individual blisters come into contact.
  • the main body must at least be large enough for a bubble for receiving a medicinal product portion to be introduced and for the bubble to be closed by a cover film.
  • a typical size is, for example, an extent in the x- and y-direction from 0.6 cm to 6 cm and in the z-direction from 0.2 mm to 2 mm. However, the main body can also be larger or smaller.
  • Information regarding the medicinal product situated in the bubble is preferably applied to the cover film.
  • Information of this type can be, for example, the name of the active substance, the name of the manufacturer and/or distributor, a batch number, the expiry date, a dosage, and other information.
  • Some information is requested by authorities monitoring a circulation of medicinal products, and other information can be useful for the individuals encountering the packaged medicinal product, for example patients, doctors, care staff, transport and logistics companies, packers, etc.
  • Information regarding the time at which the medicinal product is to be taken is also useful.
  • specific colourings can be used; for example a red colour for taking the medicinal product in the morning and a blue colour for taking the medicinal product in the evening/at night is conceivable.
  • the belly side is the side on which the bubble protrudes from the main body and the side arranged opposite the side on which the cover film is applied.
  • the main body therefore has a minimum size, which makes it possible to apply at least the legally required information to the main body and/or the cover film.
  • a particular minimum size additionally offers the advantages that the individual blister will not be so quickly lost, and that it can be more easily handled and opened, in particular for older individuals.
  • information can also be introduced for example as an engraving into the main body and/or the cover film.
  • the bubble is formed in the main body. It usually serves to receive an individual medicinal product portion. However, it is also conceivable for a plurality of medicinal product portions to be situated in a bubble. For example, it is conceivable for the active substance quantity that must be taken by a patient at a defined moment in time to be too large for an individual medicinal product portion because problems can occur during swallowing. It can therefore be expedient to divide the active substance between a plurality of smaller medicinal product portions.
  • the bubble preferably contains at the most four medicinal product portions; it particularly preferably contains a single medicinal product portion.
  • the bubble can be formed in the main body centrally or in a decentralized manner.
  • the terms “centrally” and “decentralized” will be explained in greater detail further below.
  • the cover film is applied to what is referred to as the rear side of the main body and closes the bubble, which protrudes from the main body on the opposite belly side.
  • FIG. 1 illustrates this.
  • FIG. 1 shows an example of an individual blister 1 in plan view and from two sides.
  • the individual blister 1 comprises a planar main body 2 , in which a bubble 3 is formed.
  • a bubble 3 In the bubble 3 there is situated a single medicinal product portion (not illustrated in FIG. 1 ).
  • the bubble is closed by a cover film 4 .
  • the bubble 3 is formed centrally in the planar main body 2 .
  • the basic shape of the main body is rectangular—the corners being rounded.
  • the cover film extends usually, but not necessarily, over the entire rear side of the main body and terminates flush with the edges of the main body.
  • the cover film thus preferably likewise has the basic shape of the main body and in the ideal case is flat (without curvature).
  • the cover films preferably lie in planes extending parallel to one another.
  • cover films There are various possibilities for stacking which, in the case of cover films extending in parallel, are provided by the orientation of the cover films with respect to the direction of the force of gravity.
  • the cover films extend horizontally to the force of gravity and the individual blister packs are stacked “on top of one another”.
  • the cover films extend vertically to the force of gravity and the individual blister packs are stacked “adjacently”.
  • the cover films can be brought into any other orientation between “vertical” and “horizontal” by rotation of the stack.
  • the present invention is not limited to any orientation of the stack with respect to the force of gravity.
  • stack in the present description is interpreted more broadly than in colloquial language, in which case it is usually understood to mean only an “arrangement on top of one another”.
  • the term “height h S of the stack-like arrangement” also is not to be understood to mean that only individual blisters stacked “on top of one another” are the subject of the present invention.
  • the term “height” is thus interpreted here more broadly than is usually understood thereby.
  • an adjacent individual blister is to be understood to mean the individual blister that is in contact with the individual blister in question.
  • the adjacent individual blister can be situated above or below the individual blister in question.
  • the individual blister at the very bottom has only a single adjacent individual blister; this lies above the individual blister situated at the very bottom.
  • the individual blister at the very top also has just one adjacent individual blister; this lies below the individual blister situated at the very top. Should further individual blisters be provided between the individual blisters at the very bottom and at the very top, these each have two adjacent individual blisters, one of the adjacent individual blisters being situated above the individual blister in question, and the other of the adjacent individual blisters being situated below the individual blister in question. Similar considerations apply to a stack in which the individual blisters are arranged “adjacently”.
  • Typical numbers N of individual blisters in a stack-like arrangement are 2, 3, 4, 5, 6, 7, 8, 9, 10, 12, 14, 16, 18, 20, 21, 28, 30 and 31. However, other quantities are also conceivable.
  • N is an integer in the range from 2 to 31.
  • N 7.
  • N is 28.
  • the bubbles preferably point in the same direction.
  • the individual blisters it is also conceivable for the individual blisters to be arranged rear side to rear side and belly side to belly side in alternation. Mixed forms of the specified stack forms are also conceivable.
  • the height h S of the stack-like arrangement is N times the sum of the height h B of a bubble, the thickness d G of a flat main body and the thickness d D of a cover film:
  • the stack height is reduced in accordance with the invention:
  • h S ( N ⁇ 1) ⁇ ( d G +d D +h N )+( h B +d G +d D ), where h N ⁇ h B
  • h N denotes the height of the supporting structures, which will be described in greater detail further below.
  • the individual blisters are stacked such that the cover film of an individual blister rests on the main body of an adjacent individual blister in a region that lies beside the bubble.
  • FIG. 3 illustrates this embodiment.
  • FIG. 3 shows an example of an arrangement according to the invention in plan view (bottom) and from a side (top). Seven examples ( 1 - 1 , 1 - 2 , 1 - 3 , 1 - 4 , 1 - 5 , 1 - 6 , 1 - 7 ) of the individual blister 1 from FIG. 1 are arranged on top of one another in a stack-like manner. All bubbles point in the same direction.
  • the individual blister 1 - 1 is arranged at the very bottom in the stack.
  • the individual blister 1 - 2 rests on the individual blister 1 - 1 .
  • the cover film of the individual bubble 1 - 2 rests on the main body of the adjacent individual bubble 1 - 1 , more specifically in a region beside the bubble.
  • the belly side B is therefore the side on which the bubble 3 protrudes from the main body 2 .
  • the rear side R is the side on which the cover film 4 is applied that closes the bubble 3 .
  • the height of the stack-like arrangement shown in FIG. 3 is:
  • F E is, here, the area content of a single individual blister in the projection onto the plane disposed parallel to the basic shape of the planar main body (xy plane), and F O is the overlap region of two adjacent individual blisters in the same projection plane.
  • the area requirement of a stack-like arrangement according to the invention is smaller than the area requirement of adjacently arranged individual blisters, since the individual blisters of the stack-like arrangement overlap in the xy projection plane.
  • F O rel is from 0.3 to 1, particularly preferably from 0.5 to 1.
  • the size of the relative overlap region can be maximized in different ways, for example by a decentralized arrangement of the bubbles and/or by recesses in the main body, as will be explained in greater detail hereinafter.
  • the bubbles of the individual blisters are arranged in a decentralized manner with respect to the basic shape of the planar main body.
  • the centre of the basic shape of the planar main body is determined either by its centre of symmetry or, if the basic shape has no centre of symmetry, by the centre of gravity of the basic shape.
  • the bubble also has a centre, which is determined either by the centre of symmetry or, if the bubble has no centre of symmetry, by the centre of gravity of the bubble.
  • a decentralized arrangement of the bubble is to be understood to mean an arrangement in which the centre of the bubble does not coincide with the centre of the basic shape of the planar main body.
  • FIGS. 4 and 5 illustrate this embodiment.
  • FIG. 4 shows an example of an individual blister 1 in plan view and from two sides.
  • the individual blister 1 comprises a planar main body 2 , in which a bubble 3 is formed.
  • a bubble 3 In the bubble 3 there is situated an individual medicinal product portion (not illustrated in FIG. 4 ).
  • the bubble is closed by a cover film 4 .
  • the bubble 3 is formed in the planar main body 2 in a decentralized manner.
  • the basic shape of the main body is rectangular—the corners being rounded.
  • FIG. 5 shows an example of an arrangement according to the invention in a plan view (bottom) and from a side (top). Seven examples ( 1 - 1 , 1 - 2 , 1 - 3 , 1 - 4 , 1 - 5 , 1 - 6 , 1 - 7 ) of the individual blister 1 from FIG. 4 are arranged on top of one another in a stack-like manner. All bubbles point in the same direction.
  • each individual blister has a recess, within which the bubble of an adjacent individual blister can be placed. This also results in a denser packing both in the stack direction and perpendicularly thereto.
  • FIGS. 6 and 7 illustrate this embodiment.
  • the edges of the basic shape have a convex contour.
  • a circular, a square, and a rectangular basic shape always have a convex contour (see FIG. 6 , for example). If, by contrast, a semi-circular recess is punched out in the edge region of a square basic shape, the contour of the basic shape is no longer convex at all points, but is concave in the region of the recess.
  • basic areas with recess is to be understood to mean all basic areas where the contour, besides convex regions, also comprises at least one concave region.
  • the recess is preferably round, semi-circular, ellipsoidal, semi-ellipsoidal, or rectangular.
  • FIG. 6 shows an example.
  • the two individual blisters 1 and 1 ′ behave like an image and mirror image relative to one another.
  • Both have a planar main body 2 , in which a bubble 3 for receiving a medicinal product portion is formed.
  • the bubble is arranged in a decentralized manner with respect to the main body.
  • Both main bodies have a semi-circular recess 5 .
  • FIG. 7 shows how two of the individual blisters 1 and 1 ′ are arranged on top of one another in alternation in a stack-like manner.
  • the stack height is:
  • each individual blister has supporting structures.
  • the supporting structures can be formed in the main body, similarly to the bubble. It is also conceivable for the supporting structures to be applied to the main body. In accordance with the invention, the supporting structures have a lower height than the bubble: h N ⁇ h B .
  • the height of the stack-like arrangement is:
  • FIG. 8 shows an example.
  • a bubble 3 is arranged in a decentralized manner in the main body 2 of the individual blister 1 .
  • a circular recess 5 is formed in the main body 2 , in which recess a bubble of a further individual blister in a stack-like arrangement can be placed.
  • the main body also has supporting structures in the form of two supporting nubs 7 , of which the height h N is less than the height of the bubble h B .
  • FIG. 9 two of the individual blisters from FIG. 8 are stacked on top of one another.
  • the lower individual blister is rotated through 180° relative to the upper individual blister, such that the bubble of the lower individual blister falls precisely into the recess in the upper individual blister.
  • the main body of the upper individual blister rests on the supporting nubs of the lower individual blister.
  • the height of the stack-like arrangement is:
  • a special form of a “base area with recess” is the angular base area, which constitutes a particularly preferred embodiment.
  • the recess is rectangular.
  • An example of an angular base area is shown in FIG. 10 .
  • An angular base area is understood to mean an area in which two area elements extend in different directions starting from a common area and delimit a free region between the area elements.
  • the bubble of an individual blister falls into the free region between the area elements of the main body of an adjacent individual blister.
  • the area elements extending in different directions enclose an angle of less than 180°.
  • the angle preferably lies in a range from 120° to 60°, particularly preferably in a range from 100° to 80°; and the angle is most preferably 90°.
  • the area elements extending in different directions are preferably of the same shape; they are preferably rectangular. They can be the same size or different sizes. In a preferred embodiment they are the same size; in another preferred embodiment they are different sizes.
  • FIG. 10 an individual blister having an angular main body is illustrated.
  • the main body 2 comprises two rectangular area elements 6 and 6 ′, which are arranged at an angle of 90° to one another and delimit a free region, in which the bubble of a further individual blister in a stack-like arrangement can be placed.
  • the main body 2 has supporting structures in the form of supporting nubs 7 , of which the height h N is less than the height h B of the bubble 3 .
  • FIG. 11 shows, in a plan view (bottom) and in a side view (top), how two of the individual blisters from FIG. 10 are stacked on top of one another.
  • the stack height is:
  • the bubble of each individual blister of a stack according to the invention is arranged in a decentralized manner with respect to the basic shape of the main body, and the main body additionally has a recess, in which the bubble of an adjacent individual blister can be placed.
  • FIGS. 12 and 13 illustrate this embodiment.
  • an individual blister 1 is illustrated, of which the main body 2 has two rectangular area elements 6 and 6 ′, which are arranged at an angle of 90° to one another and delimit a free region, in which the bubble of a further individual blister can be placed in a stack-like arrangement.
  • FIG. 13 shows how three of the individual blisters from FIG. 12 are stacked on top of one another in a spiraled manner.
  • the stack height is:
  • FIGS. 14, 15, 16 and 17 show further embodiments of the present invention, in which the medicinal product portion and accordingly also the bubble have an elongate form.
  • an individual blister 1 is illustrated, of which the main body 2 has two rectangular area elements 6 and 6 ′, which are arranged at an angle of 90° to one another and delimit a free region, in which the bubble of a further individual blister in a stack-like arrangement can be placed.
  • the area elements 6 and 6 ′ are of different sizes.
  • FIG. 15 three of the individual blisters from FIG. 15 are stacked on top of one another.
  • FIG. 16 shows an individual blister 1 , in the main body 2 of which a bubble 3 is arranged in a decentralized manner.
  • a recess 5 is introduced into the main body 2 , into which recess a bubble of a further individual blister in a stack-like arrangement can be placed.
  • the main body also has supporting structures in the form of four supporting nubs 7 , of which the height h N is less than the height of the bubble h B .
  • FIG. 17 two of the individual blisters from FIG. 16 are stacked on top of one another.
  • the lower individual blister is rotated through 180° relative to the upper individual blister, such that the bubble of the lower individual blister falls precisely into the recess in the upper individual blister.
  • the main body of the upper individual blister rests on the supporting nubs of the lower individual blister.
  • a further subject of the present invention is a box containing a stack-like arrangement according to the invention of individual blisters.
  • the box serves as secondary packaging. It usually also contains a package leaflet containing information regarding taking the medicinal product portions.
  • the box serves to stabilize the stack-like arrangement according to the invention. It consists for example of card, plastic, metal or also a composite material.
  • the box is a folding box made of card, as is also used for conventional blister strips.
  • the box contains a viewing window, via which the remaining amount of individual blisters provided in the box can be determined.
  • the box has a lateral opening in the lower region of the box, via which a single individual blister can be removed from the box.
  • the individual blisters remaining in the box move down when the lower individual blister is removed and can be individually removed in succession until the box is empty.
  • FIG. 18 three boxes according to the invention are illustrated.
  • the right-hand box contains seven individual blisters, the middle box contains fourteen individual blisters, and the left-hand box contains 28 individual blisters.
  • the left-hand box has a viewing window on its side, via which viewing window the remaining number of individual blisters can be determined.
  • the left-hand box also has an opening in the lower region, via which the individual blisters can be removed laterally.
  • a further subject of the present invention is constituted by individual blisters embodied in a particular manner in order to enable a stacking according to the invention.
  • the individual blisters are characterized in that the bubble is arranged in a decentralized manner with respect to the main body. Particularly preferred embodiments are illustrated in FIGS. 4, 6, 8, 12, 14 and 16 .
  • the individual blisters have a recess, in which the bubble of an adjacent individual blister in a stack-like arrangement according to the invention can be placed. Particularly preferred embodiments are illustrated in FIGS. 6, 8, 10, 12, 14 and 16 .
  • the individual blisters have supporting structures, of which the height h N is less than the height of the bubble h B .
  • the main body of the individual blister according to the invention has a rectangular or square basic shape, in which the corners are optionally rounded. Particularly preferred embodiments are illustrated in FIGS. 4, 6, 8 and 16 .
  • the main body of the individual blister according to the invention has an angular basic shape, in which the corners are optionally rounded. Particularly preferred embodiments are illustrated in FIGS. 10, 12 and 14 .
  • the individual blister exists in two different copies, which behave like an image and mirror image relative to one another.
  • a particularly preferred embodiment is illustrated in FIG. 6 .
  • planar main bodies have one or more basic shapes which, apart from optionally rounded corners, allows/allow a tesselation of a rectangular area.
  • Tesselation (also referred to as tiling, paving or scrap-free blanking) is understood to mean the covering of an area by smaller areas of identical shape, with no gaps and no overlaps.
  • the basic shapes of the planar main bodies form the sub-areas here.
  • the advantage of tesselation lies in the fact that the main body can be obtained by dividing a larger blister sheet, wherein division leftovers (cutting leftovers, waste) are reduced to a minimum.
  • FIGS. 1, 4, 8, 10, 12, 14 and 16 allow a tesselation.
  • a further subject of the present invention is a method for producing individual blisters according to the invention.
  • the method according to the invention is characterized in that the individual blisters are separated off from a sheet or a web comprising a multiplicity of individual blisters.
  • the separation can be implemented by conventional methods, such as laser cutting, mechanical cutting, punching, etching, electron beam machining, ultrasound and water jet. These and further methods are described, for example, in DIN standards 8588, 8589 and 8590.
  • the individual blisters are produced from a macro blister pack, which is described in greater detail in EP15182316.8.

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Chemical & Material Sciences (AREA)
  • Composite Materials (AREA)
  • Packages (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Stackable Containers (AREA)
  • Auxiliary Devices For And Details Of Packaging Control (AREA)
  • Auxiliary Apparatuses For Manual Packaging Operations (AREA)
US15/761,737 2015-09-22 2016-09-19 Individual blister packs for optimized stacking Abandoned US20180282040A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP15186159.8A EP3147233A1 (de) 2015-09-22 2015-09-22 Einzelblisterpackungen zur optimierten stapelung
EP15186159.8 2015-09-22
PCT/EP2016/072094 WO2017050665A1 (de) 2015-09-22 2016-09-19 Einzelblisterpackungen zur optimierten stapelung

Publications (1)

Publication Number Publication Date
US20180282040A1 true US20180282040A1 (en) 2018-10-04

Family

ID=54198972

Family Applications (1)

Application Number Title Priority Date Filing Date
US15/761,737 Abandoned US20180282040A1 (en) 2015-09-22 2016-09-19 Individual blister packs for optimized stacking

Country Status (20)

Country Link
US (1) US20180282040A1 (ko)
EP (2) EP3147233A1 (ko)
JP (1) JP2018527262A (ko)
KR (1) KR20180054790A (ko)
CN (1) CN108025847B (ko)
AU (1) AU2016328423A1 (ko)
CA (1) CA2999102A1 (ko)
CL (1) CL2018000758A1 (ko)
CO (1) CO2018003056A2 (ko)
CR (1) CR20180179A (ko)
EA (1) EA201890798A1 (ko)
HK (1) HK1250363A1 (ko)
IL (1) IL258028A (ko)
MA (1) MA42916A (ko)
MX (1) MX2018003577A (ko)
PE (1) PE20180644A1 (ko)
PH (1) PH12018500593A1 (ko)
SG (1) SG11201802095WA (ko)
SV (1) SV2018005658A (ko)
WO (1) WO2017050665A1 (ko)

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Also Published As

Publication number Publication date
PE20180644A1 (es) 2018-04-16
EP3353086A1 (de) 2018-08-01
WO2017050665A1 (de) 2017-03-30
MX2018003577A (es) 2018-06-19
CR20180179A (es) 2018-05-28
CO2018003056A2 (es) 2018-06-12
CA2999102A1 (en) 2017-03-30
JP2018527262A (ja) 2018-09-20
MA42916A (fr) 2018-08-01
SG11201802095WA (en) 2018-04-27
EP3147233A1 (de) 2017-03-29
CL2018000758A1 (es) 2018-08-17
PH12018500593A1 (en) 2018-10-01
AU2016328423A1 (en) 2018-04-12
KR20180054790A (ko) 2018-05-24
CN108025847A (zh) 2018-05-11
EA201890798A1 (ru) 2018-10-31
CN108025847B (zh) 2019-12-31
HK1250363A1 (zh) 2018-12-14
IL258028A (en) 2018-05-31
SV2018005658A (es) 2018-10-02

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