US20090081208A1 - Optimized Fc variants and methods for their generation - Google Patents

Optimized Fc variants and methods for their generation Download PDF

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Publication number
US20090081208A1
US20090081208A1 US11/981,596 US98159607A US2009081208A1 US 20090081208 A1 US20090081208 A1 US 20090081208A1 US 98159607 A US98159607 A US 98159607A US 2009081208 A1 US2009081208 A1 US 2009081208A1
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US
United States
Prior art keywords
antibody
fc
i332e
immunoadhesin
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US11/981,596
Inventor
Gregory Alan Lazar
Arthur J. Chirino
Wei Dang
John Rudolph Desjarlais
Stephen Kohl Doberstein
Robert J. Hayes
Sher Bahadur Karki
Omid Vafa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Xencor Inc
Original Assignee
Xencor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US41443302P priority Critical
Priority to US44230103P priority
Priority to US46760603P priority
Priority to US47783903P priority
Priority to US10/672,280 priority patent/US20040132101A1/en
Application filed by Xencor Inc filed Critical Xencor Inc
Priority to US11/981,596 priority patent/US20090081208A1/en
Publication of US20090081208A1 publication Critical patent/US20090081208A1/en
Application status is Abandoned legal-status Critical

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