US20080206867A1 - Fc variants with optimized Fc receptor binding properties - Google Patents

Fc variants with optimized Fc receptor binding properties Download PDF

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Publication number
US20080206867A1
US20080206867A1 US11/981,647 US98164707A US2008206867A1 US 20080206867 A1 US20080206867 A1 US 20080206867A1 US 98164707 A US98164707 A US 98164707A US 2008206867 A1 US2008206867 A1 US 2008206867A1
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US
United States
Prior art keywords
fc
fc variant
antibody
affinity
group consisting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US11/981,647
Inventor
John R. Desjarlais
Sher Bahadur Karki
Gregory Alan Lazar
John O. Richards
Gregory L. Moore
David F. Carmichael
Original Assignee
Desjarlais John R
Sher Bahadur Karki
Gregory Alan Lazar
Richards John O
Moore Gregory L
Carmichael David F
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US72333505P priority Critical
Priority to US72329405P priority
Priority to US73969605P priority
Priority to US74196605P priority
Priority to US75069905P priority
Priority to US77435806P priority
Priority to US77996106P priority
Priority to US11/396,495 priority patent/US20060235208A1/en
Priority to US74507806P priority
Priority to US11538406A priority
Priority to US11/981,647 priority patent/US20080206867A1/en
Application filed by Desjarlais John R, Sher Bahadur Karki, Gregory Alan Lazar, Richards John O, Moore Gregory L, Carmichael David F filed Critical Desjarlais John R
Publication of US20080206867A1 publication Critical patent/US20080206867A1/en
Priority claimed from US14/210,236 external-priority patent/US20150071948A1/en
Priority claimed from US15/406,588 external-priority patent/US20170166655A1/en
Priority claimed from US15/883,006 external-priority patent/US20180360981A1/en
Application status is Abandoned legal-status Critical

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