US20040122222A1 - Instrument and method for collecting nucleic acids - Google Patents
Instrument and method for collecting nucleic acids Download PDFInfo
- Publication number
- US20040122222A1 US20040122222A1 US10/468,598 US46859804A US2004122222A1 US 20040122222 A1 US20040122222 A1 US 20040122222A1 US 46859804 A US46859804 A US 46859804A US 2004122222 A1 US2004122222 A1 US 2004122222A1
- Authority
- US
- United States
- Prior art keywords
- nucleic acid
- reagent
- solid phases
- tips
- acid capturing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M1/00—Apparatus for enzymology or microbiology
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1081—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices characterised by the means for relatively moving the transfer device and the containers in an horizontal plane
- G01N35/109—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices characterised by the means for relatively moving the transfer device and the containers in an horizontal plane with two horizontal degrees of freedom
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/0275—Interchangeable or disposable dispensing tips
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F2101/00—Mixing characterised by the nature of the mixed materials or by the application field
- B01F2101/23—Mixing of laboratory samples e.g. in preparation of analysing or testing properties of materials
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0631—Purification arrangements, e.g. solid phase extraction [SPE]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00178—Special arrangements of analysers
- G01N2035/00237—Handling microquantities of analyte, e.g. microvalves, capillary networks
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N2035/1027—General features of the devices
- G01N2035/103—General features of the devices using disposable tips
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N2035/1027—General features of the devices
- G01N2035/1048—General features of the devices using the transfer device for another function
- G01N2035/1058—General features of the devices using the transfer device for another function for mixing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/0099—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor comprising robots or similar manipulators
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/028—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having reaction cells in the form of microtitration plates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1004—Cleaning sample transfer devices
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
- Y10T436/255—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.] including use of a solid sorbent, semipermeable membrane, or liquid extraction
Definitions
- NAT nucleic-acid amplification testing
- PCR technique the polymerase chain reaction technique
- PCR technique allows nucleic acids in a solution to be amplified sequence-specifically, for example, the existence of virus, only a trace amount of which is contained in serum, may be indirectly proved by amplifying and detecting the nucleic acids, which are genes of the virus.
- JP-A No. 250681/1995 the method for purifying a DNA extraction liquid using a cartridge vessel having a quadruple-structured filtering member, wherein a glass powder layer is inserted between two glass fiber filters and membrane filters, is disclosed.
- the sample to be purified is extracted in such a manner that a prepared DNA-containing culture is pre-processed and pipetted on a trap filter, and then an elution reagent is added on it to elute plasmid DNA from a cell.
- any of substances, which can have action of dissolving the nucleic acids from the solid phase may be used, and the method, which uses a low concentration of salt solution or deionized water, is known.
- 10 mmol/L bicine (pH8.5) and 0.1 mmol/L EDTA are used.
- a third reagent bottle 19 used in Step 3a, a fifth reagent bottle 20 used in Step 5, a first reagent bottle 21 used in Step 1, a fourth reagent bottle 102 used in Step 4, a second reagent bottle 22 used in Steps 2a and 2b, and others are set.
- the arm 16 and the nozzle holders 17 automatically removed the used dispensing tips 15 by taking advantage of the action of the tip detaching device 27 .
- the arm 16 and the nozzle holders 17 attached new dispensing tips 15 , 100 ⁇ L of second reagent was aspirated from the second reagent bottle 22 , discharged into the processing vessel 24 with the mixture of the sample and the first reagent filled, the liquid was repeatedly aspirated and discharged five times, and then the whole amount of liquid was discharged into the processing vessel 24 .
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Clinical Laboratory Science (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Sustainable Development (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Sampling And Sample Adjustment (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Devices For Use In Laboratory Experiments (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12/869,519 US8183054B2 (en) | 2001-03-28 | 2010-08-26 | Instrument and method for collecting nucleic acids |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
WOPCT/JP01/02577 | 2001-03-28 | ||
PCT/JP2001/002577 WO2002078847A1 (fr) | 2001-03-28 | 2001-03-28 | Instrument et procede permettant de recuperer de l'acide nucleique |
PCT/JP2001/011212 WO2002078846A1 (fr) | 2001-03-28 | 2001-12-20 | Instrument et procede de recolte d'acides nucleiques |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US12/869,519 Division US8183054B2 (en) | 2001-03-28 | 2010-08-26 | Instrument and method for collecting nucleic acids |
Publications (1)
Publication Number | Publication Date |
---|---|
US20040122222A1 true US20040122222A1 (en) | 2004-06-24 |
Family
ID=11737173
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10/468,598 Abandoned US20040122222A1 (en) | 2001-03-28 | 2001-12-20 | Instrument and method for collecting nucleic acids |
US12/869,519 Expired - Fee Related US8183054B2 (en) | 2001-03-28 | 2010-08-26 | Instrument and method for collecting nucleic acids |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US12/869,519 Expired - Fee Related US8183054B2 (en) | 2001-03-28 | 2010-08-26 | Instrument and method for collecting nucleic acids |
Country Status (6)
Country | Link |
---|---|
US (2) | US20040122222A1 (ja) |
EP (1) | EP1374997B1 (ja) |
JP (3) | JP3619514B2 (ja) |
KR (1) | KR100505380B1 (ja) |
DE (1) | DE60121477T2 (ja) |
WO (2) | WO2002078847A1 (ja) |
Cited By (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020127705A1 (en) * | 2000-05-31 | 2002-09-12 | Volker Lehmann | Method and arrangement for taking up a first medium, which is present in a first phase, into a capillary device |
US20050042138A1 (en) * | 2003-08-20 | 2005-02-24 | Sysmex Corporation | Sample analyzer, nucleic acid detector and nucleic acid detection method |
US20050175499A1 (en) * | 2004-02-06 | 2005-08-11 | Quest Diagnostics Investments Incorporated | Method of reducing cross sample contamination during filter sampling |
US20060019407A1 (en) * | 2004-07-23 | 2006-01-26 | Fulton Scott P | Immunoassay assembly and methods of use |
US20060252142A1 (en) * | 2005-05-06 | 2006-11-09 | Hitachi High-Technologies Corporation | Method for nucleic acid isolation and an instrument for nucleic acid isolation |
US20080038740A1 (en) * | 2006-06-26 | 2008-02-14 | Blood Cell Storage, Inc. | Device and method for extraction and analysis of nucleic acids from biological samples |
US20090029867A1 (en) * | 2005-01-26 | 2009-01-29 | Reed Michael W | DNA purification and analysis on nanoengineered surfaces |
US20090111193A1 (en) * | 2007-10-31 | 2009-04-30 | Cooney Christopher G | Sample preparation device |
WO2009058432A1 (en) * | 2007-10-31 | 2009-05-07 | Akonni Biosystems | Sample preparation device |
US20090215125A1 (en) * | 2006-06-26 | 2009-08-27 | Blood Cell Storage, Inc. | Devices and processes for nucleic acid extraction |
US20110203688A1 (en) * | 2008-11-04 | 2011-08-25 | Blood Cell Storage, Inc. | Nucleic acid extraction on curved glass surfaces |
US8012349B2 (en) | 2006-11-20 | 2011-09-06 | Orbital Biosciences, Llc | Small volume unitary molded filters and supports for adsorbent beds |
US8629264B2 (en) | 2011-05-19 | 2014-01-14 | Blood Cell Storage, Inc. | Gravity flow fluidic device for nucleic acid extraction |
US20150105300A1 (en) * | 2003-02-05 | 2015-04-16 | Iquum, Inc. | Sample Processing Methods |
US9428746B2 (en) | 2007-10-31 | 2016-08-30 | Akonni Biosystems, Inc. | Method and kit for purifying nucleic acids |
US10125388B2 (en) | 2007-10-31 | 2018-11-13 | Akonni Biosystems, Inc. | Integrated sample processing system |
CN109073513A (zh) * | 2016-04-07 | 2018-12-21 | 田边工业株式会社 | 粉体采集器、粉体采集装置及自动粉体采集系统 |
US10429403B2 (en) | 2014-06-17 | 2019-10-01 | Yamaha Hatsudoki Kabushiki Kaisha | Head device for mounting dispensing tip thereon, and movement device using same |
US20210025910A1 (en) * | 2017-12-29 | 2021-01-28 | Beckman Coulter, Inc. | Probe Washing Arrangement With Multiple Configurations For Sample Analyzer And Method Of Using |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1564300A4 (en) * | 2002-11-13 | 2007-09-05 | Hitachi High Tech Corp | PROCESS FOR NUCLEIC ACID AMPLIFICATION AND DEVICE THEREFOR |
JP2004337108A (ja) * | 2003-05-16 | 2004-12-02 | Hitachi High-Technologies Corp | 核酸精製装置、核酸捕捉用チップ、及び核酸精製方法 |
JP4090443B2 (ja) * | 2004-02-24 | 2008-05-28 | 株式会社日立ハイテクノロジーズ | 核酸回収器具、その部品、及び核酸回収器具の生産方法 |
JP4699868B2 (ja) | 2005-11-04 | 2011-06-15 | 株式会社日立ハイテクノロジーズ | 核酸精製方法及び核酸精製器具 |
GB201010237D0 (en) * | 2010-06-18 | 2010-07-21 | Lgc Ltd | Methods and apparatuses |
WO2011158815A1 (ja) * | 2010-06-18 | 2011-12-22 | 東洋紡績株式会社 | 抗酸菌の溶菌とその核酸の分離を同時に行う方法 |
EP2455764A1 (en) * | 2010-11-18 | 2012-05-23 | BTP TECNO S.r.l. | Diagnostic apparatus for organic samples analysis |
KR20140066567A (ko) | 2012-11-23 | 2014-06-02 | 주식회사 엘지화학 | 리튬 이차전지용 전해액 및 이를 포함하는 리튬 이차전지 |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5188730A (en) * | 1990-05-07 | 1993-02-23 | Kronwald Separationstechnik Gmbh | Multipart chromatography column connection |
US5910246A (en) * | 1995-04-01 | 1999-06-08 | Boehringer Mannheim Gmbh | Device for isolating nucleic acids |
US6162356A (en) * | 1998-03-19 | 2000-12-19 | Hitachi, Ltd. | Chip for use in nucleic acid separation, structural element and process for forming the structural element |
US6168922B1 (en) * | 1997-04-09 | 2001-01-02 | Schleicher & Schuell, Inc. | Methods and devices for collecting and storing clinical samples for genetic analysis |
US6326189B1 (en) * | 1999-03-04 | 2001-12-04 | Hitachi, Ltd. | Nucleic acid separating vessel, a method of manufacturing the nucleic acid separating vessel, and a method for separating the nucleic acid |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3639949A1 (de) * | 1986-11-22 | 1988-06-09 | Diagen Inst Molekularbio | Verfahren zur trennung von langkettigen nukleinsaeuren |
NL8900725A (nl) * | 1989-03-23 | 1990-10-16 | Az Univ Amsterdam | Werkwijze en combinatie van middelen voor het isoleren van nucleinezuur. |
DE4321904B4 (de) * | 1993-07-01 | 2013-05-16 | Qiagen Gmbh | Verfahren zur chromatographischen Reinigung und Trennung von Nucleinsäuregemischen |
CN100365017C (zh) * | 1994-09-20 | 2008-01-30 | 日立化成工业株式会社 | 肺炎衣原体抗原多肽 |
JP4025399B2 (ja) * | 1997-10-28 | 2007-12-19 | 株式会社日立製作所 | 核酸の回収方法及び装置 |
JPH11266864A (ja) * | 1998-03-19 | 1999-10-05 | Hitachi Ltd | 核酸の精製方法および精製用装置 |
JP2000175683A (ja) | 1998-03-19 | 2000-06-27 | Hitachi Ltd | 核酸分離に用いるチップと構造体の形成方法 |
JP2000336098A (ja) * | 1999-05-28 | 2000-12-05 | Hitachi Ltd | 核酸精製装置 |
JP2000350577A (ja) * | 1999-06-09 | 2000-12-19 | Aloka Co Ltd | 核酸断片の分離方法及び核酸シークエンス前処理方法並びに装置 |
-
2001
- 2001-03-28 WO PCT/JP2001/002577 patent/WO2002078847A1/ja active Application Filing
- 2001-12-20 WO PCT/JP2001/011212 patent/WO2002078846A1/ja active IP Right Grant
- 2001-12-20 JP JP2002577100A patent/JP3619514B2/ja not_active Expired - Fee Related
- 2001-12-20 DE DE60121477T patent/DE60121477T2/de not_active Expired - Lifetime
- 2001-12-20 EP EP01274056A patent/EP1374997B1/en not_active Expired - Lifetime
- 2001-12-20 US US10/468,598 patent/US20040122222A1/en not_active Abandoned
- 2001-12-20 KR KR10-2003-7009955A patent/KR100505380B1/ko not_active IP Right Cessation
-
2004
- 2004-07-23 JP JP2004215651A patent/JP3663207B2/ja not_active Expired - Fee Related
- 2004-11-22 JP JP2004337944A patent/JP4081468B2/ja not_active Expired - Fee Related
-
2010
- 2010-08-26 US US12/869,519 patent/US8183054B2/en not_active Expired - Fee Related
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5188730A (en) * | 1990-05-07 | 1993-02-23 | Kronwald Separationstechnik Gmbh | Multipart chromatography column connection |
US5910246A (en) * | 1995-04-01 | 1999-06-08 | Boehringer Mannheim Gmbh | Device for isolating nucleic acids |
US6168922B1 (en) * | 1997-04-09 | 2001-01-02 | Schleicher & Schuell, Inc. | Methods and devices for collecting and storing clinical samples for genetic analysis |
US6162356A (en) * | 1998-03-19 | 2000-12-19 | Hitachi, Ltd. | Chip for use in nucleic acid separation, structural element and process for forming the structural element |
US6326189B1 (en) * | 1999-03-04 | 2001-12-04 | Hitachi, Ltd. | Nucleic acid separating vessel, a method of manufacturing the nucleic acid separating vessel, and a method for separating the nucleic acid |
Cited By (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020127705A1 (en) * | 2000-05-31 | 2002-09-12 | Volker Lehmann | Method and arrangement for taking up a first medium, which is present in a first phase, into a capillary device |
US7470546B2 (en) * | 2000-05-31 | 2008-12-30 | Infineon Technologies Ag | Method and arrangement for taking up a first medium, which is present in a first phase, into a capillary device |
US9708599B2 (en) * | 2003-02-05 | 2017-07-18 | Roche Molecular Systems, Inc. | Sample processing methods |
US20150105300A1 (en) * | 2003-02-05 | 2015-04-16 | Iquum, Inc. | Sample Processing Methods |
US20050042138A1 (en) * | 2003-08-20 | 2005-02-24 | Sysmex Corporation | Sample analyzer, nucleic acid detector and nucleic acid detection method |
US20050175499A1 (en) * | 2004-02-06 | 2005-08-11 | Quest Diagnostics Investments Incorporated | Method of reducing cross sample contamination during filter sampling |
US20060019407A1 (en) * | 2004-07-23 | 2006-01-26 | Fulton Scott P | Immunoassay assembly and methods of use |
US8158064B2 (en) | 2004-07-23 | 2012-04-17 | Agilent Technologies, Inc. | Immunoassay assembly and methods of use |
US20100323372A1 (en) * | 2004-07-23 | 2010-12-23 | Fulton Scott P | Immunoassay assembly and methods of use |
US7799279B2 (en) | 2004-07-23 | 2010-09-21 | Biosystem Development, Llc | Immunoassay assembly and methods of use |
US8802026B2 (en) | 2004-07-23 | 2014-08-12 | Agilent Technologies, Inc. | Immunoassay assembly and methods of use |
US20100173330A1 (en) * | 2004-07-23 | 2010-07-08 | Fulton Scott P | Immunoassay assembly and methods of use |
US20090029867A1 (en) * | 2005-01-26 | 2009-01-29 | Reed Michael W | DNA purification and analysis on nanoengineered surfaces |
US20060252142A1 (en) * | 2005-05-06 | 2006-11-09 | Hitachi High-Technologies Corporation | Method for nucleic acid isolation and an instrument for nucleic acid isolation |
US20080038740A1 (en) * | 2006-06-26 | 2008-02-14 | Blood Cell Storage, Inc. | Device and method for extraction and analysis of nucleic acids from biological samples |
US20100047808A1 (en) * | 2006-06-26 | 2010-02-25 | Blood Cell Storage, Inc. | Device and method for extraction and analysis of nucleic acids from biological samples |
US7608399B2 (en) | 2006-06-26 | 2009-10-27 | Blood Cell Storage, Inc. | Device and method for extraction and analysis of nucleic acids from biological samples |
US20090215125A1 (en) * | 2006-06-26 | 2009-08-27 | Blood Cell Storage, Inc. | Devices and processes for nucleic acid extraction |
US8771955B2 (en) | 2006-06-26 | 2014-07-08 | Blood Cell Storage, Inc. | Device and method for extraction and analysis of nucleic acids from biological samples |
US8148115B2 (en) | 2006-06-26 | 2012-04-03 | Blood Cell Storage, Inc. | Device and method for extraction and analysis of nucleic acids from biological samples |
US8163535B2 (en) | 2006-06-26 | 2012-04-24 | Blood Cell Storage, Inc. | Devices and processes for nucleic acid extraction |
US8012349B2 (en) | 2006-11-20 | 2011-09-06 | Orbital Biosciences, Llc | Small volume unitary molded filters and supports for adsorbent beds |
WO2009058432A1 (en) * | 2007-10-31 | 2009-05-07 | Akonni Biosystems | Sample preparation device |
US10093919B2 (en) | 2007-10-31 | 2018-10-09 | Akonni Biosystems, Inc. | Method and kit for purifying nucleic acids |
US8236501B2 (en) | 2007-10-31 | 2012-08-07 | Akonni Biosystems, Inc. | Apparatus, system and method for purifying nucleic acids |
US8574923B2 (en) | 2007-10-31 | 2013-11-05 | Akonni Biosystems, Inc. | Sample preparation device |
US10125388B2 (en) | 2007-10-31 | 2018-11-13 | Akonni Biosystems, Inc. | Integrated sample processing system |
US8236553B2 (en) | 2007-10-31 | 2012-08-07 | Akonni Biosystems, Inc. | Apparatus, system and method for purifying nucleic acids |
US20100240123A1 (en) * | 2007-10-31 | 2010-09-23 | Akonni Biosystems | Apparatus, System and Method for Purifying Nucleic Acids |
US20100240882A1 (en) * | 2007-10-31 | 2010-09-23 | Akonni Biosystems | Apparatus, System and Method for Purifying Nucleic Acids |
US9428746B2 (en) | 2007-10-31 | 2016-08-30 | Akonni Biosystems, Inc. | Method and kit for purifying nucleic acids |
US20090111193A1 (en) * | 2007-10-31 | 2009-04-30 | Cooney Christopher G | Sample preparation device |
US20110203688A1 (en) * | 2008-11-04 | 2011-08-25 | Blood Cell Storage, Inc. | Nucleic acid extraction on curved glass surfaces |
US8629264B2 (en) | 2011-05-19 | 2014-01-14 | Blood Cell Storage, Inc. | Gravity flow fluidic device for nucleic acid extraction |
US10429403B2 (en) | 2014-06-17 | 2019-10-01 | Yamaha Hatsudoki Kabushiki Kaisha | Head device for mounting dispensing tip thereon, and movement device using same |
CN109073513A (zh) * | 2016-04-07 | 2018-12-21 | 田边工业株式会社 | 粉体采集器、粉体采集装置及自动粉体采集系统 |
US10942093B2 (en) * | 2016-04-07 | 2021-03-09 | Tanabe Engineering Corporation | Powder collector, powder collection device, and automatic powder collecting system |
US20210025910A1 (en) * | 2017-12-29 | 2021-01-28 | Beckman Coulter, Inc. | Probe Washing Arrangement With Multiple Configurations For Sample Analyzer And Method Of Using |
Also Published As
Publication number | Publication date |
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JP2004290211A (ja) | 2004-10-21 |
EP1374997B1 (en) | 2006-07-12 |
JP3619514B2 (ja) | 2005-02-09 |
EP1374997A4 (en) | 2004-05-12 |
KR20030078897A (ko) | 2003-10-08 |
JP3663207B2 (ja) | 2005-06-22 |
US20110015381A1 (en) | 2011-01-20 |
WO2002078846A1 (fr) | 2002-10-10 |
DE60121477D1 (de) | 2006-08-24 |
JP2005110687A (ja) | 2005-04-28 |
US8183054B2 (en) | 2012-05-22 |
WO2002078847A1 (fr) | 2002-10-10 |
JPWO2002078846A1 (ja) | 2004-07-22 |
KR100505380B1 (ko) | 2005-07-29 |
JP4081468B2 (ja) | 2008-04-23 |
EP1374997A1 (en) | 2004-01-02 |
DE60121477T2 (de) | 2007-02-15 |
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