UA98969C2 - АНТИКОАГУЛЯНТНЫЕ СОЕДИНЕНИЯ, ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ НА ИХ ОСНОВЕ ДЛЯ ЛЕЧЕНИЯ тромботических состояний И ПЛАЗМОЗАМЕЩАЮЩИЙ РАСТВОР ДЛЯ КОРРЕКЦИИ ГИПЕРКОАГУЛЯНТНЫХ НАРУШЕНИЙ ПРИ ГЕМОДИЛЮЦИИ - Google Patents
АНТИКОАГУЛЯНТНЫЕ СОЕДИНЕНИЯ, ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ НА ИХ ОСНОВЕ ДЛЯ ЛЕЧЕНИЯ тромботических состояний И ПЛАЗМОЗАМЕЩАЮЩИЙ РАСТВОР ДЛЯ КОРРЕКЦИИ ГИПЕРКОАГУЛЯНТНЫХ НАРУШЕНИЙ ПРИ ГЕМОДИЛЮЦИИInfo
- Publication number
- UA98969C2 UA98969C2 UAA201000790A UAA201000790A UA98969C2 UA 98969 C2 UA98969 C2 UA 98969C2 UA A201000790 A UAA201000790 A UA A201000790A UA A201000790 A UAA201000790 A UA A201000790A UA 98969 C2 UA98969 C2 UA 98969C2
- Authority
- UA
- Ukraine
- Prior art keywords
- plasma
- hypercoagulation
- hemodilution
- defects
- correct
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 206010020608 Hypercoagulation Diseases 0.000 title abstract 2
- 239000003146 anticoagulant agent Substances 0.000 title abstract 2
- 229940127219 anticoagulant drug Drugs 0.000 title abstract 2
- 230000003027 hypercoagulation Effects 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 206010059484 Haemodilution Diseases 0.000 title 1
- 230000007547 defect Effects 0.000 title 1
- 230000001732 thrombotic effect Effects 0.000 title 1
- 206010040047 Sepsis Diseases 0.000 abstract 1
- 208000006011 Stroke Diseases 0.000 abstract 1
- 208000007536 Thrombosis Diseases 0.000 abstract 1
- 230000006378 damage Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 208000010125 myocardial infarction Diseases 0.000 abstract 1
- 230000007170 pathology Effects 0.000 abstract 1
- 210000001147 pulmonary artery Anatomy 0.000 abstract 1
- 238000001356 surgical procedure Methods 0.000 abstract 1
- 230000009424 thromboembolic effect Effects 0.000 abstract 1
- 210000003462 vein Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/40—Unsubstituted amino or imino radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2007124202/04A RU2353619C2 (ru) | 2007-06-28 | 2007-06-28 | Новые соединения, обладающие функцией антикоагулянтов, фармацевтические композиции на их основе для лечения тромботических состояний и плазмозамещающий раствор для коррекции гиперкоагуляционных нарушений при гемодилюции |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA98969C2 true UA98969C2 (ru) | 2012-07-10 |
Family
ID=40186196
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA201000790A UA98969C2 (ru) | 2007-06-28 | 2008-06-27 | АНТИКОАГУЛЯНТНЫЕ СОЕДИНЕНИЯ, ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ НА ИХ ОСНОВЕ ДЛЯ ЛЕЧЕНИЯ тромботических состояний И ПЛАЗМОЗАМЕЩАЮЩИЙ РАСТВОР ДЛЯ КОРРЕКЦИИ ГИПЕРКОАГУЛЯНТНЫХ НАРУШЕНИЙ ПРИ ГЕМОДИЛЮЦИИ |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US8426433B2 (enExample) |
| EP (1) | EP2178839A2 (enExample) |
| JP (1) | JP2010531353A (enExample) |
| KR (1) | KR20100028122A (enExample) |
| CN (1) | CN101848894B (enExample) |
| AU (1) | AU2008269258B2 (enExample) |
| CA (1) | CA2692363A1 (enExample) |
| EA (1) | EA020915B1 (enExample) |
| RU (1) | RU2353619C2 (enExample) |
| UA (1) | UA98969C2 (enExample) |
| WO (1) | WO2009002229A2 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2354647C2 (ru) * | 2007-06-28 | 2009-05-10 | Общество С Ограниченной Ответственностью "Бионика" | Новые соединения, обладающие функцией ингибиторов тромбина, и фармацевтические композиции на их основе |
| RU2353619C2 (ru) * | 2007-06-28 | 2009-04-27 | Общество С Ограниченной Ответственностью "Бионика" | Новые соединения, обладающие функцией антикоагулянтов, фармацевтические композиции на их основе для лечения тромботических состояний и плазмозамещающий раствор для коррекции гиперкоагуляционных нарушений при гемодилюции |
| EA021562B1 (ru) * | 2012-08-15 | 2015-07-30 | Общество С Ограниченной Ответственностью "Гематологическая Корпорация" | Устройство мониторинга пространственного свертывания крови и ее компонентов |
| CN116444506A (zh) * | 2014-02-07 | 2023-07-18 | 艾克赛特赫拉制药有限责任公司 | 治疗化合物和组合物 |
| RU2685261C1 (ru) * | 2018-04-05 | 2019-04-17 | Общество с ограниченной ответственностью "ФК ЛАБОРАТОРИЗ" | Вещество 4-амино-1-{ 2-[3-метил-5-(бензолсульфонилокси)фенокси] этил} -пиридиний хлорид, обладающее свойствами биологически активного агента, влияющими на естественно текущие процессы свертываемости крови млекопитающих, антикоагулянт на его основе и способ его получения путем химического синтеза |
| CN114080382B (zh) * | 2019-06-19 | 2024-05-24 | 株式会社Lg化学 | 制备吲哚或吲唑化合物的方法 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1245937B (enExample) * | 1964-09-09 | 1967-08-03 | ||
| US5089634A (en) * | 1984-08-20 | 1992-02-18 | Georgia Tech Research Corporation | Isocoumarins with cationic substituents |
| JPH0341065A (ja) * | 1989-07-06 | 1991-02-21 | Morishita Pharmaceut Co Ltd | アリールオキシアルキルイソチオウレア臭化水素酸塩類 |
| JP3084458B2 (ja) * | 1991-11-08 | 2000-09-04 | コニカ株式会社 | ハロゲン化銀写真感光材料 |
| TW257757B (enExample) * | 1993-03-03 | 1995-09-21 | Boehringer Mannheim Gmbh | |
| IL109319A0 (en) * | 1993-04-27 | 1994-07-31 | Du Pont Merck Pharma | Amidino and guanidino substituted boronic acid compounds |
| US5510369A (en) * | 1994-07-22 | 1996-04-23 | Merck & Co., Inc. | Pyrrolidine thrombin inhibitors |
| DE4430757A1 (de) * | 1994-08-30 | 1996-03-07 | Boehringer Mannheim Gmbh | Neue 4-Aminopyridazine, Verfahren zu ihrer Herstellung sowie diese Verbindungen enthaltende Arzneimittel |
| US5792769A (en) * | 1995-09-29 | 1998-08-11 | 3-Dimensional Pharmaceuticals, Inc. | Guanidino protease inhibitors |
| ATE341317T1 (de) * | 1996-03-29 | 2006-10-15 | Ortho Mcneil Pharm Inc | Amidinohydrazone als protease-inhibitoren |
| GB9613718D0 (en) * | 1996-06-29 | 1996-08-28 | Thrombosis Res Inst | Thrombin inhibitors |
| AU725403B2 (en) * | 1996-09-13 | 2000-10-12 | Merck & Co., Inc. | Thrombin inhibitors |
| US5792799A (en) * | 1996-10-10 | 1998-08-11 | Athena Neurosciences, Inc. | Parenteral delivery of MAO A inhibitors |
| US5886191A (en) * | 1997-08-18 | 1999-03-23 | Dupont Pharmaceuticals Company | Amidinoindoles, amidinoazoles, and analogs thereof |
| UA75093C2 (en) * | 2000-10-06 | 2006-03-15 | Dimensional Pharm Inc | Aminopyridinyl-,aminoguanidinyl-, and alkoxyguanidinesubstituted phenylsubstituted phenylacetamides as protease inhibitors |
| JP4896387B2 (ja) * | 2003-09-30 | 2012-03-14 | 武田薬品工業株式会社 | チアゾリン誘導体およびその用途 |
| AU2005229505B2 (en) * | 2004-03-02 | 2010-07-15 | F. Hoffmann-La Roche Ag | 4- (sulfanyl-pyrimidin-4-ylmethyl) -morpholine derivatives and related compounds as GABA receptor ligands for the treatment of anxiety, depression and epilepsy |
| RU2300385C1 (ru) * | 2005-12-27 | 2007-06-10 | Елена Ивановна Синауридзе | Раствор для коррекции первичных нарушений гемостаза плазмозамещающими растворами нового состава |
| CA2647597A1 (en) * | 2006-05-31 | 2007-12-06 | Abbott Laboratories | Thiazole compounds as cannabinoid receptor ligands and uses thereof |
| RU2353619C2 (ru) * | 2007-06-28 | 2009-04-27 | Общество С Ограниченной Ответственностью "Бионика" | Новые соединения, обладающие функцией антикоагулянтов, фармацевтические композиции на их основе для лечения тромботических состояний и плазмозамещающий раствор для коррекции гиперкоагуляционных нарушений при гемодилюции |
| RU2354647C2 (ru) * | 2007-06-28 | 2009-05-10 | Общество С Ограниченной Ответственностью "Бионика" | Новые соединения, обладающие функцией ингибиторов тромбина, и фармацевтические композиции на их основе |
-
2007
- 2007-06-28 RU RU2007124202/04A patent/RU2353619C2/ru not_active IP Right Cessation
-
2008
- 2008-06-27 AU AU2008269258A patent/AU2008269258B2/en not_active Ceased
- 2008-06-27 EP EP08794029A patent/EP2178839A2/en not_active Withdrawn
- 2008-06-27 KR KR1020107002061A patent/KR20100028122A/ko not_active Abandoned
- 2008-06-27 US US12/666,250 patent/US8426433B2/en not_active Expired - Fee Related
- 2008-06-27 CA CA002692363A patent/CA2692363A1/en not_active Abandoned
- 2008-06-27 UA UAA201000790A patent/UA98969C2/ru unknown
- 2008-06-27 EA EA201000064A patent/EA020915B1/ru not_active IP Right Cessation
- 2008-06-27 JP JP2010514672A patent/JP2010531353A/ja active Pending
- 2008-06-27 WO PCT/RU2008/000401 patent/WO2009002229A2/en not_active Ceased
- 2008-06-27 CN CN200880104823.1A patent/CN101848894B/zh not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU2008269258B2 (en) | 2012-12-13 |
| RU2353619C2 (ru) | 2009-04-27 |
| JP2010531353A (ja) | 2010-09-24 |
| AU2008269258A1 (en) | 2008-12-31 |
| WO2009002229A3 (en) | 2009-03-12 |
| CN101848894B (zh) | 2014-08-20 |
| CA2692363A1 (en) | 2008-12-31 |
| EA020915B1 (ru) | 2015-02-27 |
| RU2007124202A (ru) | 2009-01-10 |
| CN101848894A (zh) | 2010-09-29 |
| EA201000064A1 (ru) | 2010-06-30 |
| KR20100028122A (ko) | 2010-03-11 |
| EP2178839A2 (en) | 2010-04-28 |
| WO2009002229A2 (en) | 2008-12-31 |
| US20110003826A1 (en) | 2011-01-06 |
| US8426433B2 (en) | 2013-04-23 |
| AU2008269258A8 (en) | 2010-03-25 |
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