UA97639C2 - ОКТАГИДРОПИРОЛО[3,4-b]ПИРРОЛЬНЫЕ ПРОИЗВОДНЫЕ, СПОСОБ ИХ ПОЛУЧЕНИЯ И ИХ ПРИМЕНЕНИЕ В КАЧЕСТВЕ РЕЦЕПТОРОВ ГИСТАМИНА-3 - Google Patents

ОКТАГИДРОПИРОЛО[3,4-b]ПИРРОЛЬНЫЕ ПРОИЗВОДНЫЕ, СПОСОБ ИХ ПОЛУЧЕНИЯ И ИХ ПРИМЕНЕНИЕ В КАЧЕСТВЕ РЕЦЕПТОРОВ ГИСТАМИНА-3

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Publication number
UA97639C2
UA97639C2 UAA200811465A UAA200811465A UA97639C2 UA 97639 C2 UA97639 C2 UA 97639C2 UA A200811465 A UAA200811465 A UA A200811465A UA A200811465 A UAA200811465 A UA A200811465A UA 97639 C2 UA97639 C2 UA 97639C2
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UA
Ukraine
Prior art keywords
alkyl
ccycloalkyl
alkoxy
ris
octahydro
Prior art date
Application number
UAA200811465A
Other languages
English (en)
Ukrainian (uk)
Inventor
Марлон Д. КАУЭРТ
Чень Чжао
Миньхуа Суй
Лоуренс А. Блек
Го Чжу Чжен
Роберт Дж. Грегг
Джефф Г.З. ЧЖАН
Ахмад Й. ШЕЙКХ
Сяочунь ЛОУ
Роджер Ф. ГЕНРИ
Девид М. Барнс
Лоуренс КОЛАЦКОВСКИ
Энтони Р. Хейт
Соу Джень Чан
Стивен Дж. ВИТТЕНБЕРГЕР
Майкл Г. ФИКС
Original Assignee
Эбботт Лабораториз
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38325247&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA97639(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Эбботт Лабораториз filed Critical Эбботт Лабораториз
Publication of UA97639C2 publication Critical patent/UA97639C2/ru

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
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    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
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    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
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    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
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  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Psychiatry (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Reproductive Health (AREA)
  • Otolaryngology (AREA)
  • Psychology (AREA)
  • Addiction (AREA)
  • Hospice & Palliative Care (AREA)
  • Communicable Diseases (AREA)
  • Anesthesiology (AREA)
  • Rheumatology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Oncology (AREA)
  • Emergency Medicine (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Nutrition Science (AREA)
  • Gynecology & Obstetrics (AREA)

Abstract

Раскрыты октагидропирроло[3,4-b]пиррольные производные формулы I и II, пригодные для лечения состояний или расстройств, которые предотвращаются или облегчаются с помощью лигандов рецептора гистамина-3.Раскрыты октагидропирроло[3,4-b]пиррольные соединения, применение таких соединений, композиции, содержащие эти соединения, и способы получения таких соединений.
UAA200811465A 2006-02-24 2007-02-16 ОКТАГИДРОПИРОЛО[3,4-b]ПИРРОЛЬНЫЕ ПРОИЗВОДНЫЕ, СПОСОБ ИХ ПОЛУЧЕНИЯ И ИХ ПРИМЕНЕНИЕ В КАЧЕСТВЕ РЕЦЕПТОРОВ ГИСТАМИНА-3 UA97639C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US77650906P 2006-02-24 2006-02-24
PCT/US2007/062329 WO2007100990A2 (en) 2006-02-24 2007-02-16 Octahydro-pyrrolo[3,4-b] pyrrole derivatives and their use as histamine-3 receptor ligands

Publications (1)

Publication Number Publication Date
UA97639C2 true UA97639C2 (ru) 2012-03-12

Family

ID=38325247

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200811465A UA97639C2 (ru) 2006-02-24 2007-02-16 ОКТАГИДРОПИРОЛО[3,4-b]ПИРРОЛЬНЫЕ ПРОИЗВОДНЫЕ, СПОСОБ ИХ ПОЛУЧЕНИЯ И ИХ ПРИМЕНЕНИЕ В КАЧЕСТВЕ РЕЦЕПТОРОВ ГИСТАМИНА-3

Country Status (21)

Country Link
US (2) US7728031B2 (ru)
EP (1) EP2001885A2 (ru)
JP (1) JP5463038B2 (ru)
KR (2) KR20140097612A (ru)
CN (2) CN102827167A (ru)
AU (1) AU2007220889B2 (ru)
BR (1) BRPI0708258A2 (ru)
CA (1) CA2641624A1 (ru)
CR (2) CR10287A (ru)
EC (1) ECSP088687A (ru)
GT (1) GT200800166A (ru)
IL (1) IL193270A0 (ru)
MX (1) MX2008010805A (ru)
MY (2) MY149513A (ru)
NO (1) NO20084056L (ru)
NZ (2) NZ570235A (ru)
RU (1) RU2492172C2 (ru)
SG (2) SG188878A1 (ru)
TW (1) TWI389910B (ru)
UA (1) UA97639C2 (ru)
WO (1) WO2007100990A2 (ru)

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US20070232612A1 (en) 2007-10-04
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