UA90763C2 - Производные пиразола, способ их получения, фармацевтический состав на их основе и их применение - Google Patents
Производные пиразола, способ их получения, фармацевтический состав на их основе и их применениеInfo
- Publication number
- UA90763C2 UA90763C2 UAA200805973A UAA200805973A UA90763C2 UA 90763 C2 UA90763 C2 UA 90763C2 UA A200805973 A UAA200805973 A UA A200805973A UA A200805973 A UAA200805973 A UA A200805973A UA 90763 C2 UA90763 C2 UA 90763C2
- Authority
- UA
- Ukraine
- Prior art keywords
- rrepresents
- calkyl
- rand
- preparation
- pharmaceutical composition
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/18—One oxygen or sulfur atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Gynecology & Obstetrics (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Pregnancy & Childbirth (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73509105P | 2005-11-08 | 2005-11-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA90763C2 true UA90763C2 (ru) | 2010-05-25 |
Family
ID=37909834
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200805973A UA90763C2 (ru) | 2005-11-08 | 2006-10-26 | Производные пиразола, способ их получения, фармацевтический состав на их основе и их применение |
Country Status (35)
| Country | Link |
|---|---|
| US (2) | US7309712B2 (ru) |
| EP (1) | EP1948615B1 (ru) |
| JP (1) | JP4234786B1 (ru) |
| KR (1) | KR100997595B1 (ru) |
| CN (1) | CN101304974A (ru) |
| AP (1) | AP2008004463A0 (ru) |
| AR (1) | AR056780A1 (ru) |
| AT (1) | ATE537150T1 (ru) |
| AU (1) | AU2006313478A1 (ru) |
| BR (1) | BRPI0618630A2 (ru) |
| CA (1) | CA2628844C (ru) |
| CR (1) | CR9959A (ru) |
| CY (1) | CY1112286T1 (ru) |
| DK (1) | DK1948615T3 (ru) |
| DO (1) | DOP2006000245A (ru) |
| EA (1) | EA014693B1 (ru) |
| EC (1) | ECSP088431A (ru) |
| ES (1) | ES2376252T3 (ru) |
| GT (1) | GT200600478A (ru) |
| HN (1) | HN2006037713A (ru) |
| IL (1) | IL190806A0 (ru) |
| MA (1) | MA29940B1 (ru) |
| NL (1) | NL2000299C2 (ru) |
| NO (1) | NO20082504L (ru) |
| PE (1) | PE20070642A1 (ru) |
| PL (1) | PL1948615T3 (ru) |
| PT (1) | PT1948615E (ru) |
| RS (1) | RS20080191A (ru) |
| SI (1) | SI1948615T1 (ru) |
| TN (1) | TNSN08202A1 (ru) |
| TW (1) | TWI321563B (ru) |
| UA (1) | UA90763C2 (ru) |
| UY (1) | UY29904A1 (ru) |
| WO (1) | WO2007054770A2 (ru) |
| ZA (1) | ZA200803670B (ru) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL126999A (en) | 1996-07-24 | 2002-03-10 | Warner Lambert Co | Pharmaceutical preparations containing isobutylgaba and its history for use in the treatment of pain |
| AU2006313478A1 (en) * | 2005-11-08 | 2007-05-18 | Pfizer Limited | Pyrazole derivatives and their medical use |
| CA2657247A1 (en) | 2006-07-28 | 2008-01-31 | Boehringer Ingelheim International Gmbh | Compounds which modulate the cb2 receptor |
| CA2664310A1 (en) | 2006-09-25 | 2008-04-03 | Boehringer Ingelheim International Gmbh | Compounds which modulate the cb2 receptor |
| WO2008135824A1 (en) * | 2007-05-02 | 2008-11-13 | Pfizer Limited | Oxyalkylpyrazole compounds useful in therapy |
| EP2217565B1 (en) | 2007-11-07 | 2013-05-22 | Boehringer Ingelheim International GmbH | Compounds which modulate the cb2 receptor |
| JP2010043063A (ja) | 2008-05-09 | 2010-02-25 | Agency For Science Technology & Research | 川崎病の診断及び治療 |
| WO2009140089A2 (en) * | 2008-05-13 | 2009-11-19 | Boehringer Ingelheim International Gmbh | Sulfone compounds which modulate the cb2 receptor |
| JP5749162B2 (ja) | 2008-07-10 | 2015-07-15 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Ｃｂ２受容体を調節するスルホン化合物 |
| US8372874B2 (en) | 2008-09-25 | 2013-02-12 | Boehringer Ingelheim International Gmbh | Compounds which selectively modulate the CB2 receptor |
| US8299103B2 (en) | 2009-06-15 | 2012-10-30 | Boehringer Ingelheim International Gmbh | Compounds which selectively modulate the CB2 receptor |
| JP5756800B2 (ja) | 2009-06-16 | 2015-07-29 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Ｃｂ２受容体を調節するアゼチジン２−カルボキサミド誘導体 |
| JP2013505295A (ja) | 2009-09-22 | 2013-02-14 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Ｃｂ２受容体を選択的に調節する化合物 |
| US10610528B2 (en) | 2009-12-08 | 2020-04-07 | Intelgenx Corp. | Solid oral film dosage forms and methods for making same |
| US20110136815A1 (en) * | 2009-12-08 | 2011-06-09 | Horst Zerbe | Solid oral film dosage forms and methods for making same |
| EP2523936A1 (en) | 2010-01-15 | 2012-11-21 | Boehringer Ingelheim International GmbH | Compounds which modulate the cb2 receptor |
| JP5746228B2 (ja) | 2010-03-05 | 2015-07-08 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Ｃｂ２受容体を選択的に調節するテトラゾール化合物 |
| US20110263606A1 (en) * | 2010-04-26 | 2011-10-27 | Horst Zerbe | Solid oral dosage forms comprising tadalafil |
| EP2595959B1 (en) | 2010-07-22 | 2015-11-04 | Boehringer Ingelheim International GmbH | Sulfonyl compounds which modulate the cb2 receptor |
| EP2803668A1 (en) | 2013-05-17 | 2014-11-19 | Boehringer Ingelheim International Gmbh | Novel (cyano-dimethyl-methyl)-isoxazoles and -[1,3,4]thiadiazoles |
| AU2019362242A1 (en) * | 2018-10-18 | 2021-05-27 | Nanjing Sanhome Pharmaceutical Co., Ltd. | Compound as TGF-β R1 inhibitor and application thereof |
| RU2711615C1 (ru) * | 2019-09-12 | 2020-01-17 | Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт акушерства, гинекологии и репродуктологии имени Д.О. Отта" | Способ лечения эндометриоза на основании экспериментальной модели у крыс |
| CN111269097B (zh) * | 2020-04-02 | 2023-02-17 | 苏州爱玛特生物科技有限公司 | 一种多元环双取代的1,3-丙二酮类化合物的合成方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6281638A (ja) * | 1985-10-07 | 1987-04-15 | Fuji Photo Film Co Ltd | ハロゲン化銀カラ−写真感光材料 |
| JPS63313784A (ja) * | 1987-03-12 | 1988-12-21 | Zeria Shinyaku Kogyo Kk | 新規ピラゾール誘導体およびその製造法ならびにこれを有効成分とする抗潰瘍剤 |
| DE4414792A1 (de) * | 1993-08-11 | 1995-02-16 | Bayer Ag | Arzneimittel enthaltend 1-Thiocarbamoyl-5-hydroxypyrazolen und deren Verwendung als Mittel zur Bekämpfung des septischen Schocks |
| RS51166B (sr) * | 2001-04-10 | 2010-10-31 | Pfizer Inc. | Derivati pirazola za tretiranje hiv |
| GB0229618D0 (en) * | 2002-12-19 | 2003-01-22 | Cancer Rec Tech Ltd | Pyrazole compounds |
| AU2006313478A1 (en) * | 2005-11-08 | 2007-05-18 | Pfizer Limited | Pyrazole derivatives and their medical use |
-
2006
- 2006-10-26 AU AU2006313478A patent/AU2006313478A1/en not_active Abandoned
- 2006-10-26 PT PT06809167T patent/PT1948615E/pt unknown
- 2006-10-26 WO PCT/IB2006/003080 patent/WO2007054770A2/en active Application Filing
- 2006-10-26 CA CA2628844A patent/CA2628844C/en not_active Expired - Fee Related
- 2006-10-26 EP EP06809167A patent/EP1948615B1/en active Active
- 2006-10-26 RS RSP-2008/0191A patent/RS20080191A/sr unknown
- 2006-10-26 KR KR1020087010982A patent/KR100997595B1/ko not_active IP Right Cessation
- 2006-10-26 UA UAA200805973A patent/UA90763C2/ru unknown
- 2006-10-26 PL PL06809167T patent/PL1948615T3/pl unknown
- 2006-10-26 DK DK06809167.7T patent/DK1948615T3/da active
- 2006-10-26 AT AT06809167T patent/ATE537150T1/de active
- 2006-10-26 JP JP2008539519A patent/JP4234786B1/ja not_active Expired - Fee Related
- 2006-10-26 SI SI200631237T patent/SI1948615T1/sl unknown
- 2006-10-26 EA EA200801053A patent/EA014693B1/ru not_active IP Right Cessation
- 2006-10-26 AP AP2008004463A patent/AP2008004463A0/xx unknown
- 2006-10-26 CN CNA2006800416684A patent/CN101304974A/zh active Pending
- 2006-10-26 ES ES06809167T patent/ES2376252T3/es active Active
- 2006-10-26 BR BRPI0618630-0A patent/BRPI0618630A2/pt not_active IP Right Cessation
- 2006-11-02 NL NL2000299A patent/NL2000299C2/nl not_active IP Right Cessation
- 2006-11-03 US US11/592,574 patent/US7309712B2/en not_active Expired - Fee Related
- 2006-11-06 PE PE2006001366A patent/PE20070642A1/es not_active Application Discontinuation
- 2006-11-07 HN HN2006037713A patent/HN2006037713A/es unknown
- 2006-11-07 AR ARP060104881A patent/AR056780A1/es unknown
- 2006-11-07 GT GT200600478A patent/GT200600478A/es unknown
- 2006-11-07 TW TW095141158A patent/TWI321563B/zh active
- 2006-11-08 DO DO2006000245A patent/DOP2006000245A/es unknown
- 2006-11-08 UY UY29904A patent/UY29904A1/es not_active Application Discontinuation
-
2007
- 2007-10-11 US US11/870,451 patent/US7425569B2/en not_active Expired - Fee Related
-
2008
- 2008-04-10 IL IL190806A patent/IL190806A0/en unknown
- 2008-04-25 ZA ZA200803670A patent/ZA200803670B/xx unknown
- 2008-05-06 EC EC2008008431A patent/ECSP088431A/es unknown
- 2008-05-07 TN TNP2008000202A patent/TNSN08202A1/fr unknown
- 2008-05-08 CR CR9959A patent/CR9959A/es not_active Application Discontinuation
- 2008-05-08 MA MA30910A patent/MA29940B1/fr unknown
- 2008-06-05 NO NO20082504A patent/NO20082504L/no not_active Application Discontinuation
-
2012
- 2012-01-27 CY CY20121100096T patent/CY1112286T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| UA90763C2 (ru) | Производные пиразола, способ их получения, фармацевтический состав на их основе и их применение | |
| EP1562949A4 (en) | METHOD FOR PRODUCING PYRROLOTRIAZIN COMPOUNDS SUITABLE AS KINASEINHIBITORS | |
| TW200612936A (en) | Indole derivatives | |
| AR061656A1 (es) | Compuesto de bencilpiperazina, su uso para preparar un medicamento, composicion farmaceutica que lo comprende y procesos para la preparacion de la composicion y del compuesto | |
| MY147442A (en) | Imidazoquinolines as lipid kinase inhibitors | |
| WO2010064875A3 (en) | Novel indazole derivatives or pharmaceutically acceptable salts thereof as protein kinase inhibitors for proliferative diseases treatment, and a pharmaceutical composition containing the same as an active ingredient | |
| GEP20104962B (en) | Fused heterocyclic compounds | |
| TW200806311A (en) | Neuropeptide-2 receptor-agonists | |
| NO20083427L (no) | Cystoksiske midler omfattende nye tomaymycinderivater og deres terapeutiske anvendelse | |
| ATE512961T1 (de) | Amorphes nebivolol hydrochlorid und seine herstellung | |
| EA201070167A1 (ru) | Замещенные производные индазола, активные как ингибиторы киназы | |
| NO20072371L (no) | Kinuklidinderivater og deres anvendelse som muskarine M3-reseptorantagonister | |
| NO20064522L (no) | Novel pharmaceutical compositions | |
| MX2010006230A (es) | Derivados de arilamida substituidos con triazol y su uso como antagonistas de receptor purinergico p2x3 y/o p2x2/3. | |
| NO20064706L (no) | Thyroid reseptor agonister | |
| EA200870302A1 (ru) | 1,3-диоксанкарбоновые кислоты | |
| MX2007006387A (es) | Derivados de piridina 3-substituidos como antagonistas h3. | |
| CY1108246T1 (el) | ΠΑΡΑΓΩΓΑ 1Η-ΘΕΙΕΝΟ[2,3-c] ΠΥΡΑΖΟΛΗΣ ΧΡΗΣΙΜΑ ΩΣ ΑΝΑΣΤΟΛΕΙΣ ΚΙΝΑΣΗΣ | |
| MXPA04002338A (es) | Derivados de carbazol y su uso como antagonistas receptores del npy5. | |
| TW200616952A (en) | Novel crystal form of (3-cyano-1h-indol-7-yl)-[4-(4-fluorophenethyl)piperazin-1-yl]-methanone, hydrochloride | |
| NO20076060L (no) | Piperidin-4-yl-amidderivater og deres anvendelse som SST-reseptor subtype 5-antagonister | |
| DE60217843D1 (de) | Ein dioxinoä2,3-güchinolin-9-carbonsäure derivat als nk3 rezeptor antagonist | |
| ATE399156T1 (de) | Neue indol- oder benzimidazol-derivate | |
| Luo et al. | Synthesis and Anti‐Hepatitis B Virus Activity of a Novel Class of Thiazolylbenzimidazole Derivatives | |
| ATE318266T1 (de) | 3-substituierte chinolin-4- carbonsäureamidderivate als nk-3- und nk-2- rezeptorantagonisten |